Spur_PTPRB5
Species: S.purpuratus
Alias: hmm39492, Spur_PTPRB5, Spur_hmm182150
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RB
Protein domain

Protein domains of Spur_PTPRB5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Fn3 Spur_PTPRB5.AA FN3 85-161 20 2e-06 28.28 SMART 1-69 (69) Show / Hide
Range on Protein: 85-161
Range on HMM: 1-69/69
Sequence Identity: 20% (19 aa)

PREPGT---IDVEELTST------SISITWTEFAGITDYIVNLTLASNNTELFSGVIRSSLKASFSGLMPG----EEYIIKIGLQC---AGEV
|  |.    . |.. |||      |....|..   |. |.                      . ..|| ||     || ...       ||| 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 511-591 24 2.6e-09 38.18 SMART 1-69 (69) Show / Hide
Range on Protein: 511-591
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PLPPVN---IETADSQLT------SLLIAWSDPGNETMFDRYYVAYERADELGNFTEVGYLYPNVTSIFLEGLTPR----TEYLFNVSTV----VGEG
| || |   ..  |   |      |. . |. |                       .|||         ..||.|     ||| | |. |    .|||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-----------------------IVGYR------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 1087-1166 21 3.9e-14 54.19 SMART 1-69 (69) Show / Hide
Range on Protein: 1087-1166
Range on HMM: 1-69/69
Sequence Identity: 21% (20 aa)

PSPPSS---VTITAVSSR------LIEIRWTPPPNIAEMVLEYFDTESPSNTWEARIDNDGMYDIHGLDAD----TSYTVRLSSVGRTGAGDG
|.||.    ...|.|.|.       ....|.||      ...|                   | ..|| ..    | |..|.. | ...|| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 1271-1348 21 5.4e-09 37.12 SMART 1-69 (69) Show / Hide
Range on Protein: 1271-1348
Range on HMM: 1-69/69
Sequence Identity: 21% (20 aa)

PSPPES---LRVVDETIT------TLRIEWDSPASGLYRGFEVDISPPTALQELPRIVGSDIRGFTFVGLMHN----SEYTVSVTTI----MGEE
|.||.    |||.| | |      .....|. |      |..                      .|. ||  .    .||...|. .     || 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 1433-1514 19 4.6e-08 34.04 SMART 1-69 (69) Show / Hide
Range on Protein: 1433-1514
Range on HMM: 1-69/69
Sequence Identity: 19% (19 aa)

PERPDG---LELESVGPY------SLD--WKVDTSLNDLNYERLEVSYSPESSQTDSPFDISRCTDGTFTLEGLQPD----TEYSVSVTAISG--DTRS
|  | .   |....|..       |.   ||             .|.|.                   .|..||.|.    |||...|.|..|  . ..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-----------IVGYR-------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 1613-1691 17 6.4e-10 40.19 SMART 1-69 (69) Show / Hide
Range on Protein: 1613-1691
Range on HMM: 1-69/69
Sequence Identity: 17% (17 aa)

PAPPGP---ITLQSSTQT------RLSFTWTPATSNFDSYELSISGGDMPEPRPVGVVYPNEGNEFEVGGLLPD----TTYNVRIYSV----FFES
| ||.    ... . | |       .. .|.|      .|.                        . | || |.    |.|..|.. |      |.
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 2266-2345 21 3.7e-09 37.68 SMART 1-69 (69) Show / Hide
Range on Protein: 2266-2345
Range on HMM: 1-69/69
Sequence Identity: 21% (21 aa)

PLPVNN---VTLDDSTIF------TLTISWENPIDGSFNMFLVEYAPVRSPDSVMALDPINMGTNTAIIPNLQPG----TLYNIMVYAL----AGEE
| |. |   ... | |        ..|.||. |         |.|                     .....|.||    | |.. |.|     ||| 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR--------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 2815-2888 23 2.9e-09 38.01 SMART 1-69 (69) Show / Hide
Range on Protein: 2815-2888
Range on HMM: 1-69/69
Sequence Identity: 23% (21 aa)

PDKPTD---IMLSDLTTT------SLTIDWKAPLTSYQGFRLCWAYGETNSLELGPAVMERTLSDLEAG----AEYLVSLAAV----VGTG
|. |..   . ..| |.|      |.|. ||.|     |.|                    |...|..|     || ....||    .| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR-------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 2905-2985 19 9e-06 26.41 SMART 1-69 (69) Show / Hide
Range on Protein: 2905-2985
Range on HMM: 1-69/69
Sequence Identity: 19% (19 aa)

PPAELH---VNITSFNTT------AVSIVWGTDIPLLDVSSYVVSYWETANNGSVQDISVDDPSQTDYTIDGLVPG----TRYSFMVDAL----GTVQ
|..  .   . .|. ..|       |.. |    |       .|.|.                    ||..||.||    |.|.| | |     .   
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWK--PP-------IVGYR--------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 3195-3276 14 2e-06 28.77 SMART 1-69 (69) Show / Hide
Range on Protein: 3195-3276
Range on HMM: 1-69/69
Sequence Identity: 14% (14 aa)

PESAVD---LQFTSIGRN------YVVLTWDNPAGMIDSYNISYYPVNDITKLMFEVVQAAAESNVLRVDDLNEG----MNYSFTVVSLLE--VEAD
| .  .   |..|.....       |.|.|. |        ..|                       .|..| .|     .|.|.|.   .  .   
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 3373-3452 23 2.6e-11 44.83 SMART 1-69 (69) Show / Hide
Range on Protein: 3373-3452
Range on HMM: 1-69/69
Sequence Identity: 23% (22 aa)

PNPPTN---LRTTMVAAQ------SITVSWDPPSEGGSDTYNITYNVTGGQPPSPHTVSTSETSVTFSNLTPL----TEYFFTIVNIWK--SLPS
| ||.|   || | | .       |.|.||.||         ..|                   .|...|.|     ||| |... . .    ..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 3655-3730 18 4.8e-11 43.94 SMART 1-69 (69) Show / Hide
Range on Protein: 3655-3730
Range on HMM: 1-69/69
Sequence Identity: 18% (17 aa)

PDPPQN---LVISEIGED------TATLSWADPAEMNFDILEVVMTTMPATKTTILKLNTNTVELTNLVPG----QTYTVQLASV----IRPD
|.||.|   |........      ..||||  |      |.. .                  . .|.|.||    ..|..... |      . 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Fn3 Spur_PTPRB5.AA FN3 3752-3830 20 8.5e-12 46.43 SMART 1-69 (69) Show / Hide
Range on Protein: 3752-3830
Range on HMM: 1-69/69
Sequence Identity: 20% (19 aa)

PASPSD---ISVSNNELT------RVTVTWQPSEGVVARYSYTYGLPGSTVTASETTTTTDTSIQLSNLTPS----TRYEFRLWAESD--QTEG
| .|..   ..|..   |       ||..|.|    . .|.                        ...|.|     |.||||..|...  . ||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Phosphatase Spur_PTPRB5.AA Subfamily.N23.PD 4039-4515 31 1.7e-55 179.8 In-house 18-347 (350) Show / Hide
Range on Protein: 4039-4515
Range on HMM: 18-347/350
Sequence Identity: 31% (100 aa)

ARRTRPVPSYQTTPDDYNPFADGAGVTtfrvgsqscdpddltaycngalypgtsyrfairaygvdgkfvdtefsspfrtdpdrgifvipaivlaimvvii
.| |   | | | | . ||  .   .. ..    .  ...  . ..||.   .|. |. . ..      . .||. .|. ...   . ..      | .|
srptaskpeyltrppeinpqgpvetlw-------------------------------------------------------------------------

liifmamgfgccgkpddgmysddsngygndysngngysngngngimkralindgvntyayqqpqimehsftnipdystippnrgttaqVHQPSTThTRPT
|.|.|||||.|.|.   .  ..||||||...|.  || ||||.|.|.|||.|  |||.|.||..|||. | |..|.|...|.|   ......|||.| |.
----------------------------------------------------------------------------------------seledyq-gqea

KKNMFAQHVAKMSARNNAGFSDEYNNL-PAMEKTRAVTAARQARNDDKNRYRN--ILPYDYTRVQLK----GVAGTDYINASYIKDDH-GQKKYIATQGP
.. ..  |.|.| .. .|...|||.|   |. .| .|. .       . .|..  ||..||||||||||||      . ....    |..   . ..|.|
iaadqsiasakrmsnknrqfnpdllpyhlqpttitavpqprhlqtegsGqqqgtpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgP

LPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWPAGE-EPQLHGNVTVTLVGSNQTDNFIERTLLLEKEGTE--RTVTHYQYLAWTDHGVPESTA
|   ||.  ..  | . ||                                                                                 
iastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPe

PLVGLLRQVKVTN------QEDGAATGPIVVHCSAGVGRTGTFIAADMLMDAIQrsTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
                                                                                              
dllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelt--agngiiniprvvrrlrqqRkymvqkkvilkklyeavle

Phosphatase Spur_PTPRB5.AA PTPc 4257-4518 36 3.4e-122 413.18 SMART 1-308 (308) Show / Hide
Range on Protein: 4257-4518
Range on HMM: 1-308/308
Sequence Identity: 36% (115 aa)

GFSDEYNNLPAMEKTR---------AVTAARQARND--DKNRYR-NILPYDYTRVQLKGV-------AGTDYINASYIKDDHGQKKYIATQGPLPNTIEH
||..|...|..|....           | |.   |   |||||. .|..||.||| ||          |.|||||.||. ....|.||.||||||.|||.
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWEMVWENQTSTIVMMTALVEG--------GKTKCEHYWPAGEEPQLHGNVTVTLVGSNQTD-NFIERTLLLEKEG----------TERTVTHYQYLAWT
|| |||......|||.. ..|.        |. ||..|||    |. .|. |||..  .... ... ||. ... |           .||||||.| .| 
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DHGVPESTAPLVGLLRQVKVTNQEDGAA----------------TGPIVVHCSAGVGRTGTFIAADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQT
|||||||. ..  ..|||. ...  . .                |||||||||||.||||||.|.|.... |..      .|. ... ..|.||. .|||
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN------VDIFQIVKMMRNQRPGMVQT

LYQYIYLHRTVLSLIE
. |||...| .| .|.
EEQYIFCYRCILEYIK

Phosphatase Spur_PTPRB5.AA Y_phosphatase 4282-4515 40 6.2e-115 392.92 Pfam 1-243 (243) Show / Hide
Range on Protein: 4282-4515
Range on HMM: 1-243/243
Sequence Identity: 40% (101 aa)

NDDKNRYRNILPYDYTRVQLK---GVAGTDYINASYIKD-DHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGK-TK-CEHYWPA--GEE
| .||||..|..||.||| |.   |  ..|||||.||.  .. .|.||.||||.|.|||.|| |||......|||.. ..|.|.  | |..|||    ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

PQLHGNVTVTLVGSNQTDNFIERTLLLEKEGT----ERTVTHYQYLAWTDHGVPES-TAPLVGLLRQVKVTNQEDGAATG--PIVVHCSAGVGRTGTFIA
|. .|. .||.|  ....... ||. ... |.    .||||||.|..|.||||||| . ... ..|||.  ..      |  |||||||||.||||||.|
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP--NPDHGCPPIVVHCSAGCGRTGTFCA

ADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
.|.... ....      |. ... ..|.||. .|||. |||......| 
IDIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Spur_PTPRB5.AA Subfamily.RB.PD 4258-4517 51 3.1e-108 352.5 In-house 2-260 (261) Show / Hide
Range on Protein: 4258-4517
Range on HMM: 2-260/261
Sequence Identity: 51% (135 aa)

FSDEYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQL---KGVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMT
||.||..| ...|..||.||..| |..|||..||||||..||.|   |  ..||||||.||.. . ...|||||||||.|...||.||||...|.|||.|
fseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

ALVEGGKTKCEHYWPAGEEPQLHGNVTVTLVGSNQTDNFIERTLLLEKEGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEDgAATGPIVVHC
 |||.||.|||.|||| |||.|.|...|||. ....|... |.. .||. ..|.|..|....|.||||||.|..|. ..|.|.. ... |...|||||||
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekk-askkPivvHC

SAGVGRTGTFIAADMLMDAIQRstaTDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
||||||||||| |.|..||..   .||.||.|..|..||.|.|||||. |||..|...|.|. 
saGvGRtGtfialdrllqaiee---ndyvdvfgvvaelReeRnllvqtekqyifiheclldll

Phosphatase Spur_PTPRB5.AA Subfamily.N_Choan_1.PD 4257-4517 40 2.2e-83 271.1 In-house 1-261 (262) Show / Hide
Range on Protein: 4257-4517
Range on HMM: 1-261/262
Sequence Identity: 40% (108 aa)

GFSDEYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQL---KGVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMM
||  ||..| ....  . ||...  |  ||||.||  || |||..   .    ||||||....  .|.|.|||||||.|.....||.||||.. |.|||.
GfieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmv

TALVEGGKTKCEHYWPAGEEPQLHGNVTVTLVGSNQTDNFIERTLLL-EKEGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEDGAatGPIVV
|. .|.|| || .||| ...    |.|||. . .... ..|||.. | ...| .|.|.. .|.|| |||||..|. |..  ..|. .....     |.|.
treieagklkChryWPdenselklgdvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk--aplvi

HCSAGVGRTGTFIAADMLMDAIQrsTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
|||||||||||.|| | |..|..  . .. .||  ..|..|..| |.|||| ||.....||  . 
hCsaGvGrtGtyialDrlvkave--ekaealdvkavvaelrkernlmvqtlvqyefvykavldal

Phosphatase Spur_PTPRB5.AA Subfamily.R_Anemone_2.PD 4258-4517 44 2.5e-82 267.7 In-house 2-261 (262) Show / Hide
Range on Protein: 4258-4517
Range on HMM: 2-261/262
Sequence Identity: 44% (119 aa)

FSDEYNNL-PAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLK---GVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMM
.| ||..| .. |..  ...| .  |  |||| |||.|| |||.|.   |. |.|||||.||   . .|.|||||.|||.||||| |||| ....|||.|
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TALVEGGKTKCEHYWPaGEEPQLHGNVTVTLVGSNQTDNFIERTLLLEKEG--TERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEDGAatGPIV
 ..| ||.|...||| ..... .|...|.|  . ...... |.. .....   ||.|  ..| .|.|.|||||.| |. |.|||. ..|| ||  |||||
tqeeergkakvhryWP-skgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesga--gpiv

VHCSAGVGRTGTFIAADMLmdaIQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
||||||||||.||| |.|   ..|  |   .|| .|. ..|||| |.|||  ||.... ..|  . 
vhcsaGvGrtGvfiavdil---lerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase Spur_PTPRB5.AA Subfamily.N12.PD 4268-4517 43 3e-78 254.0 In-house 18-269 (270) Show / Hide
Range on Protein: 4268-4517
Range on HMM: 18-269/270
Sequence Identity: 43% (108 aa)

MEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLK---GVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKC
.||. . .|... .|  ||||..|||||..||.|.   .. | |||||..||  .|...|||.|||||.|.. || |.|| ... .||..|| ||.|||.
aekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkC

EHYWPAGEEPQL-HGNVTVTLVGSNQTD-NFIERTLLLEKEGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQedgAATGPIVVHCSAGVGRTG
|||   | .| .|...|||   ...| .|. ||| .|.....|.|. ..| || |||||.|. .|. |...|. ....   |.||||||||||||| || 
eryWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqe---sedaPlvvhCsaGvGrtG

TFIAADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
|.  ..... . .. .||   ....|.||| ||||  || .....|..|.     
tiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv

Phosphatase Spur_PTPRB5.AA Subfamily.N6.PD 4254-4517 39 6.9e-78 253.3 In-house 10-294 (295) Show / Hide
Range on Protein: 4254-4517
Range on HMM: 10-294/295
Sequence Identity: 39% (112 aa)

NNAGFSDEYNNLP--AMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKG----VAGTDYINASYIK-----------DDH--GQKKYIATQGPLPNT
.  ||..|...|   ..||.   . .....| .||||.||||.| ||| ||     |.|.|||||.||.            .    ||.||||||.|..|
qtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdt

IEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWPAGEEPQLHGNVTVTLVGSNQTDNFIERTLLLE---KEGTERTVTHYQYLAWTDHGVPESTAPLVG
.. ||.|||....  |||.|  || || || .|||. |. . .|..||| .  ..|.... |.....   |. ..|.. .|..|| |||||...  .. .
vsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvln

LLRQVKVTNQEDgAATGPIVVHCSAGVGRTGTFIAADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
|..|. ...|    .||||||||||.|||||||  |.... |..| .   ||.  .| ..|.||. ||||  ||... ..|  .| 
fledvnkkqeel-ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi

Phosphatase Spur_PTPRB5.AA Subfamily.R_Sponge_2.PD 4261-4517 40 2.3e-77 251.4 In-house 5-261 (262) Show / Hide
Range on Protein: 4261-4517
Range on HMM: 5-261/262
Sequence Identity: 40% (105 aa)

EYNNLPaMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKG--VAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVE
|..... .|.   ...|..  |  |||...||||| .||.|.   . ..||||||..   . .| ||||||||..|.| || |||| ..|||||.| |.|
eeksve-ketefslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnlee

GGKTKCEHYWPAG-EEPQLHGNVTVTLVGSNQTDNFIERTLLLEKEGT---ERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEDGAatGPIVVHC
 || ||..|||   .| .  |...|||. .... ..| |.| | || .   |..||.....||..|.||.....|. |...|. .....|   ..|.|.|
ngkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgn--kaitvvC

SAGVGRTGTFIAADMLMDAIqrsTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
|.|||||||||| |.... .    | . |||  .....| .|  |||.  ||..|  .|..| 
sdgvgrtGtfialdsvlerl---kaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi

Phosphatase Spur_PTPRB5.AA Subfamily.R_Anemone_1.PD 4258-4515 38 1.6e-76 248.8 In-house 2-255 (258) Show / Hide
Range on Protein: 4258-4515
Range on HMM: 2-255/258
Sequence Identity: 38% (100 aa)

FSDEYNNLPaMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGV---AGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMT
...|...|   .|.  . .||.|.| .|||| .|...| .|| |. .     .|||||||..  ......||||.||..|.||| |||......|||.| 
yaaefqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLt

ALVEGGKTKCEHYWPAgeEPQLHGNVTVTLVGSNQTDNFIERTLLLEKEGT--ERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTnQEDGaaTGPIVV
|.|| |.||..|||   ... .|...|.|  ...  ..| |||.|.|...  ||.|..|... |.|.|||. .. ..||.|.|. . .. |  . |.|||
nliegekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-slag--arpvvv

HCSAGVGRTGTFIAADMLMDAIQRStatDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
|||||||||.|.. | ... ....     .|.  .. .|||.|. .|||  ||...|..||  
hCsaGvgRtGaflvidamleqakke---kvvDifnyvkairedrphmvqtkeqyvfihlavle

Phosphatase Spur_PTPRB5.AA Subfamily.N13.PD 4259-4517 39 7.5e-76 246.4 In-house 3-258 (259) Show / Hide
Range on Protein: 4259-4517
Range on HMM: 3-258/259
Sequence Identity: 39% (105 aa)

SDEYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVAGtdYINASYIKDDHGQK--KYIATQGPLPNTIEHFWEMVWENQTSTIVMMTAL
..|...|  .  .  .. .....| |||||||.|||| |||.|.. .|  |||||.||   |..  .|||.|||||.|.. || |||| ... |.|.|  
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtle

VEGGKTKCEHYWPAGEEPQL--HGNVTVTLVGSNQTDNFIERTLLLEKEGT--ERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQedgaATGPIVV
.|.|| ||. |||  .. .|  .. ..|.|.. .. |.|  |.| ...  .   | |.| .. .| ||||| |.|.|| ....|.  ..     .|||||
kekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt----dagPivv

HCSAGVGRTGTFIAADMLMDAIQRSTatdYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
|||||.||.|..|. |.... |.| .    .||  .. |.||||  .|||  |||. ....| ..
hcsaGiGrsGvlitidvvlglierdk---efdvkeivrklreqrqgvvqtkdqyifvykailevl

Phosphatase Spur_PTPRB5.AA Subfamily.N3.PD 4264-4515 40 7.8e-74 239.5 In-house 8-258 (261) Show / Hide
Range on Protein: 4264-4515
Range on HMM: 8-258/261
Sequence Identity: 40% (102 aa)

NLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVAGtDYINASYIKDDHGQ----KKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEG
.|   .   |..|||...| .|||||.||||| |||.||     |||||.|.. .       ..||||||||..| ..||.||||.....|||.| ||| 
elyrkkpglaisaarkpenlaknryrdilpydatrvklkeset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlver

GKTKCEHYWPAGEEPQLHGNVTVTLVGSNQTDNFIERTLLLEKEG--TERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNqedGAATGPIVVHCSAG
|..|| .|||  |. . .|...|..  ...| ... | |.|...    ||.... |||||.|||||...| .. ....|. .... |.|||||||.||||
GrvkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr---sgkeePvvvhCsaG

VGRTGTFIAADMLMDAIQRSTATDYIDVagtIAKIREQRALLVQTLYQYIYLHRTVLS
 .|. .. .  |... .   .|.   . ..|.||| ||||  || ..  ..|      
igrtGvlilletalalieaaepvypldi---vrtmrdqramlvqtvsqykfvCeailk

Phosphatase Spur_PTPRB5.AA Subfamily.N_Choan_2.PD 4270-4516 39 2.5e-72 234.6 In-house 9-264 (266) Show / Hide
Range on Protein: 4270-4516
Range on HMM: 9-264/266
Sequence Identity: 39% (100 aa)

KTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVAG---TDYINASYIK-DDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCE
..   .    |||   |||..|||   |||.|. .     | |||| |..  |. .|||||..||||.|...|| |.||.....|||.| |.| |..|||
evseeaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCe

HYWPAGEEPQL---HGNVTVTLVGSNQTDNFIERTLLLEKEGTERTVTHYQYLAWTDHGVPESTA------PLVGLLRQVKVTNQEDGAATgPIVVHCSA
 ||||  . ..   .|...|. . ..... .| . | |||.|..|...|..| .| |||||...|. .||.|. ...|   |. |..||||||||||||.
rYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkae-PllvHcsa

GVGRTGTFIAADMLMDAIQRSTAtdyIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSL
|| |. . ......    .||.  |...|..|  |||.  || .|...|..         
GvgRtGtliaiDiavrlLeetkk---vdvlaiieelRkdRmalvqhpeqyellykavvey

Phosphatase Spur_PTPRB5.AA Subfamily.RG.PD 4258-4517 35 3.5e-71 231.1 In-house 2-263 (264) Show / Hide
Range on Protein: 4258-4517
Range on HMM: 2-263/264
Sequence Identity: 35% (94 aa)

FSDEYNNLPAMEKTR-AVTAARQARNDDKNRYRNILPYDYTRVQLKGVAG---TDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMM
........  ....   ...... .|  |||. ||.... .||.|....|   .||||||||.  . .|.||.|||||..||| || |.||.....|||.
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TALVEGGKTKCEHYWPAGEEPQLHGNVTVTLVGSNQTDNFIERTLLLEK----EGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEdgaATGP
| |.| |. ... |||. .||   ....|||.  ....... |...|..    ...||.|..|.|  | |.|.||||.. ... . .|.|   ..|||||
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaanke---eaGP

IVVHCSAGVGRTGTFIAADMLMDAIQRStatDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
|.||||||.||.|| | |.  ...    . ..| ... .|| .|  ||.|  ||.... ..|.|.   
ivvhdsaGvgragtyialdtllqqleke---eavnvyqvlklirakRpglvtteEqyvfiydallelv

Phosphatase Spur_PTPRB5.AA Subfamily.N9.PD 4257-4515 38 9.9e-71 229.8 In-house 1-272 (275) Show / Hide
Range on Protein: 4257-4515
Range on HMM: 1-272/275
Sequence Identity: 38% (105 aa)

GFSDEYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVA---GTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMM
| | || .. ... .  ..|...  | .|||| ..| || |||.|. .     .|||||....  . .| .|||||||..|.. || ||||... .|||.
GlskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmt

TALVEGGKTKCEHYWPAGEE-PQLHGNVTVTLVGSNQTDNFIERTLLLE--KEGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVK---------VTNQ
| .|| |. || .||| .||  . .|...|. |. ...... .|.| ..  |.. .|.|||.|.|.| |.|||.|.| |. .|..|.         ....
trvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde

EDGAATG-PIVVHCSAGVGRTGTFIAADMLMDAIQRstaTDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
. | ..| |||||||||.|||||||. |. .. ...   .. .||  |. ..|.|||  .||  || . . .|| 
skghlsgPPivvhcsaGiGrtGtfitldiclarlee---vgtvdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase Spur_PTPRB5.AA Subfamily.RA.PD 4258-4516 36 3.5e-70 227.8 In-house 2-264 (266) Show / Hide
Range on Protein: 4258-4516
Range on HMM: 2-264/266
Sequence Identity: 36% (96 aa)

FSDEYNNLPAMEKT-RAVTAARQARNDDKNRYRNILPYDYTRVQL---KGVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMM
. .|...|....     . .| .  | .|||. .|||||..|| |   .|.  .||||||.|.  . ..|.||.|||. .|.| || |.||...||||.|
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

TALVEGGKTKCEHYWPAgEEPQLHGNVTVTLVGSNQTDNFIERTLLLE------KEGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEDGaaT
 | | ...||  |||  |    .|...|..  .. . ..  | .|..      .| ..| |. . . .| . ||| ..  ..||..|| ..|. .    |
telkerkeekcaqywpd-eGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsa--n

GPIVVHCSAGVGRTGTFIAADMLMDAIQrstATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSL
||||||||||||||||. | ... ..   | . .|| ... ..| ||. .|||| || ......|    
hpivvhcsaGvGrtGtfivldavlervk---aerkldvfeavkrlrlqrpqmvqtleqyefiykvlley

Phosphatase Spur_PTPRB5.AA Subfamily.N5_RR.PD 4260-4514 34 1.2e-69 226.0 In-house 4-261 (265) Show / Hide
Range on Protein: 4260-4514
Range on HMM: 4-261/265
Sequence Identity: 34% (92 aa)

DEYNNLPAMEKTRAvtaARQARNDDKNRYRNILPYDYTRVQLKGVAG----TDYINASYIKDDHG-QKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMT
.|. .||.  ...     . ...  ||||..||| . .|| |.   .    ..|||| |||  .. .| |.||||||||||. ||.|....... |||.|
keflelPlnfsqee---levfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmlt

ALVEGGKTKCEHYWPAGEEP---QLHGNVTVTLVGSNQTDNFIERTLLLEKEGT-ERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEDGAATGPI
 | |  ..||..|.|  |.    . .|.| .. .. ......  |.|.|..    ||.|.|| | .| || .|... .|. |...|. ...|. | ..|.
klkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPv

VVHCSAGVGRTGTFIAADMLMDAIQRstaTDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVL
|||||||.|||| |||... .  ...   .  .|| ......| .|  .|||  || ..||.. 
vvhcsaGiGrtGcfiaisiavrqlre---eivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase Spur_PTPRB5.AA Subfamily.R_Ecdysozoa.PD 4258-4515 39 3.1e-69 224.5 In-house 2-266 (269) Show / Hide
Range on Protein: 4258-4515
Range on HMM: 2-266/269
Sequence Identity: 39% (105 aa)

FSDEYNNLPAM-EKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVAG---TDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMM
.  ||..|.|  |  .  ... .  |  ||||..| ..| |||.|| . |   .||||||.||  . .||.|| |.|. .||.|| |..| .  .|||..
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TALVEGGKTkCEHYWPAGEEPQlHGNVTVTLVGSNQTDNFIERTLLLEKEG-----TERTVTHYQYLAWT-DHGVPESTAPLVGLLRQVKVTNQED--GA
 | |  .  |..|||  .| | .|.. |.|| .......|.|.| . | .      .| |. |.|.|  |  |||..  |. |..||.  .. .    . 
snlteknrk-cakyWpiedevq-ygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

ATGPIVVHCSAGVGRTGTFIAADMLMdaiQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
.||||||||||||.|.|.| |.|.   |.  | | .|.  |. |.|.||.|||| | ||..|.| ..   
srsPivvhCsaGvgrsgifvaldlll---qqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase Spur_PTPRB5.AA Subfamily.RK.PD 4258-4516 34 4.1e-67 217.5 In-house 2-265 (267) Show / Hide
Range on Protein: 4258-4516
Range on HMM: 2-265/267
Sequence Identity: 34% (93 aa)

FSDEYNNL---PAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVAG--TDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVM
. .|.. |       ..  . .| . || .|||. .||.|| ..|.|. | |  .|||||..|   .  ...|.|||||..|.. || .|.......|||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivm

MTAL-VEGGKTKCEHYWPAGEEpQLHGNVTVTLVGSNQTDNFIERTLLLEK----EGTERTVTHYQYLAWTDH-GVPESTAPLVGLLRQVKVTNQEdgAA
.| | || |. || .|||   | . .|.. |.|| ..   ... |.. .||        |.| ..|.|.|... .||.|   |.|.|.|| ...|  .  
lteldvevgrvkClkyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee--ee

TGPIVVHCSAGVGRTGTFIAADMLMDAIQRStatDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSL
|.|||||.|| ||.||||| |.... |.|    . .||  .. ..|.... .|.|  ||....  .|   
eGrivvhClaGaGrsGtfiaidivlemiere---gvvdvfnavktlrnrkvnmveteeqykfvydvilea

Phosphatase Spur_PTPRB5.AA Subfamily.N1.PD 4270-4508 36 1.6e-63 206.1 In-house 16-258 (268) Show / Hide
Range on Protein: 4270-4508
Range on HMM: 16-258/268
Sequence Identity: 36% (86 aa)

KTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVaGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWP
|   ...|.. .| ..||||.. |||..|..|.    .|||||| .. .. ...|| ||||||.|..|||.||||... ...|.  .|| ...|| .|||
keletreaklpenrglnryrdvspydhsriklera-dvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp

AGEEP-QL--HG-NVTVTLVGSNQTDNFIERTLLLEK--EGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEdGAATGPIVVHCSAGVGRTGT
 .||  .|  .  . .|.|.  .....|. |.| ||   .   |...|..|  |.| ||||| | .. .| .|. .||.|.|||||.||.||.   | ..
qeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsL-ssdvgpavihCsagigrsgt

FIAADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIY
  |..   .. .|.   . ..|..|  |.||  |  .        
lslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrF

Phosphatase Spur_PTPRB5.AA Subfamily.N14.PD 4261-4517 36 3e-63 205.0 In-house 5-274 (275) Show / Hide
Range on Protein: 4261-4517
Range on HMM: 5-274/275
Sequence Identity: 36% (100 aa)

EYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVA--GTDYINASYIKDDHG--QKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTAL
||...| ...   ...|.   | .|||....|||. .||.|.      |.||||| ||   |  ...||..||||..|.. ||.||||.... |||.|. 
eyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmltee

VEGGKTKCEHYWPAGEEP---QLHGNVTVTLVGSNQTDNFIERTLLLEK--EGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEDG-------
 |.||.|. .|.|  |.      .|.  ||   |...| .| ..| |.    . |||| | ||  |.||||||   ...  |..|.   ..         
eedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvk

AATGPIVVHCSAGVGRTGTFIAADMLMDAIQRStatDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
 .  |..|||||||||||  | .|.|. ...     . ||.  ..|..|.|| |||||| || .......  .
eskPPvlvhCsaGvGrtGvlilsdlliatlehn---eeidikkvlarLrkqrmllvqtlaqykfvykvlikyl

Phosphatase Spur_PTPRB5.AA Subfamily.RC.PD 4258-4515 33 1.4e-61 199.6 In-house 2-285 (288) Show / Hide
Range on Protein: 4258-4515
Range on HMM: 2-285/288
Sequence Identity: 33% (96 aa)

FSDEYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQL----------------------KGVAGTDYINASYIKDDHGQKKYIATQGPLPNTI
.  |...|| .   |..  ||.  | .|||| ..||||| ||.|                      .. .|..|||||.|.  .  .||||.|||| .|.
leaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketv

EHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWpaGEEPQLHGNVTVTLVGSNQTDNFIERTLLL--EKEGTERTVTHYQYLAWTDHGVPESTAPLVGL-
. ||.|..|...  |||.| | || . || .||  .|  . .|.| | |   ... ..| | | |  .|.   |.||..|| .|.....||    |. | 
ddfwrmiferkvkvivmltelkeGdrekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkli

------LRQVKVTNQEDGAATGPIVVHCSAGVGRTGTFIAADMLMDAIQrstATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
      | | . ..  .   ..|..|||..|..|||.||| . |.....   | . .|| . . |.| .|.|.|..|||.|. .. .  
qvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesle---aeekvdvfqvvkklrkarplmvsveeqyillydvlve

Phosphatase Spur_PTPRB5.AA Subfamily.N_Nematode_1.PD 4259-4516 36 6.6e-58 187.5 In-house 3-263 (265) Show / Hide
Range on Protein: 4259-4516
Range on HMM: 3-263/265
Sequence Identity: 36% (98 aa)

SDEYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQL-KGVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALV
||...|  ....  |.| ..|...|||||...   | .||.| .. . .||| | |.      |..| .|.|| .||..||||  ..  .|||.  |.| 
rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckli

EGGKTKCEHYWPAGEEPQL--HGN---VTV-TLVG---SNQTDNFIERTLL-LEKEG-TERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTnqedgaa
||.||..|.|| |...|  . .   .|| . .|    ......|. | | .|  | ..|.|||||.  | |.|||.     . || .|..        .|
ekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs-------

TGPIVVHCSAGVGRTGTFIAADMLMDAIQRSTATDyiDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSL
|||||||||.||||| .| ....| .  ..  .  |.   . ||||||.  .||  ||...|| .|.   
kgPivvhCsaGiGrtGtivaieyildkllegkqie--dmeklvkkireqrnysiqtdaqylfvhrvllny

Phosphatase Spur_PTPRB5.AA Subfamily.RN.PD 4262-4513 38 1.1e-56 183.4 In-house 6-259 (264) Show / Hide
Range on Protein: 4262-4513
Range on HMM: 6-259/264
Sequence Identity: 38% (98 aa)

YNNLPAMEKTR-AVTAARQARNDDKNRYRNILPYDYTRVQLKGVA---GTDYINASYIKDD-HGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTAL
.. | | |    . ..|.. .| .|||....|||| .||.||  |    .|||||| | |.   .  ||||||||..|| .||.||||. .||..| | |
wealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrl

VEGGKTKCEHYWPAgEEPQLHGNVTVTLVGSN-QTDNFIERTLLLEKEG--TERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQedGaATGPIVVH
 | ..|..|||  |  ....   | ||     .|... |.. |        |||| . .|.|...||| |. .|. . |.|. .  |  . |||||||.|
eeegvkqckrywpd-eGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyr--G-rscpivvh

CSAGVGRTGTFIAADMLMDAIQRSTatDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTV
.||||..|. |.... ...      ||.| |. ..|.||. ||.|  |. .   .|    
csdGaGrtGvyilidlvlerllkGv--keidiaatlehlrdqrpglvktkdqfefaltav

Phosphatase Spur_PTPRB5.AA Subfamily.N20.PD 4274-4516 41 8.8e-53 170.9 In-house 18-255 (257) Show / Hide
Range on Protein: 4274-4516
Range on HMM: 18-255/257
Sequence Identity: 41% (103 aa)

VTAARQARNDDKNRYRNILPYDYTRVQLKgvAGTDYINASYIKDDH-G-QKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWPAG
. .  |  | .|||||.||||| ||| |      ||||||||.    | .  |||||||| .||. ||.|| ||..  | |.|  .||||| ||||   .
fnsgnqpsnreknryrdilpydstrvplg--kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpis

EEPQL-HGNVTVTLVGSNQTDNFIERTL-LLEK-EGTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTnqedgAATGPIVVHCSAGVGRTGTFIAAD
  |    . | |   .  . || | . ..||  || ..| . |.  | ||| | |.  ..  .|  . .       |||.|||||||.|||| |.. |..
lkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarks-----hltgpmvvhcsagigrtgvflcvd

MLMDAIQRSTATDYIDVagtIAKIREQRALLVQTLYQYIYLHRTVLSL
. || .  . . .|.   .|..||||. .|||  || . .  || .  
vvfcaivkncsfnimdi---vaqmreqrsgmvqtkeqyhfcydivlev

Phosphatase Spur_PTPRB5.AA Subfamily.R_Nematode_2.PD 4271-4515 35 1.2e-52 170.2 In-house 18-258 (261) Show / Hide
Range on Protein: 4271-4515
Range on HMM: 18-258/261
Sequence Identity: 35% (88 aa)

TRAVTAARQARNDDKNRYRNILPYDYTRVQLKGVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWPA
||   .  ..||.|| ..   . |.|. .       | | ..  .  .|..||||||| || | || ||  ..  .|||..  ||  |.|||.|.|  ..
kesvtesaaylpkdkhRypdvPCkpetavevivdgkrvpihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpl

GEEPQLH-GNVTVTLVGSNQ--TDNFIERTLLLEKEGT---ERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQedgaatgPIVVHCSAGVGRTGTF
 .|. |..... |. ..  .|.  .|||  |..      ||||||||  |.|.|||.| ||  ||  ||  ..       |||||||||.|||..||...
etsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek-------PivvhCsaGiGRtmaf

IAADMLMDAIQRstaTDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
.| ....     . | .. .....||.|   .||  |. .|... |.    
igteylarevea---dptieltealkelrehRwkgiqtesqlywltlgaly

Phosphatase Spur_PTPRB5.AA Subfamily.N_Nematode_6.PD 4259-4515 36 1.8e-52 169.7 In-house 3-250 (253) Show / Hide
Range on Protein: 4259-4515
Range on HMM: 3-250/253
Sequence Identity: 36% (93 aa)

SDEYNNLPAMEKTRAVTAarQARNDDKNRYRNILPYDYTRVQLKGVAgTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVE
||.. | .  .. .||    ...|.|||.||  .| .|..|..     || |...|    ....| ||.|| .|||.||.|.    .  |||.  ||| |
kkeykdspneaseseata--flkfkdrnrytniqCcdagrlkladde-dfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelve

GGKTKCEHYWPA--GEEPQLHGNVTVTLVGSNQTDNFIERTLL-LEKEGT-ERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKvtnqedgAATGPIVVHC
| |. .| .   |.. ..    ||. .| .. |  . |.|. . |.|  |  | |... .||||||.|    . ||  ||         . |||||||||
kgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvk-------kdkkPivvhC

SAGVGRTGTFIAADMLMDAIQRstaTDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLS
||||||..   ....|..    .|...|   ..|.||.|.  |||  ||.| .| ||    
saGvGrtGtlaliliilealrl---pdfqgvkdllvklreerfravqtevqylyalrcvle

Phosphatase Spur_PTPRB5.AA Subfamily.N_Nematode_4.PD 4271-4513 33 2.4e-48 156.2 In-house 15-259 (264) Show / Hide
Range on Protein: 4271-4513
Range on HMM: 15-259/264
Sequence Identity: 33% (84 aa)

TRAVTAARQARNDDKNRYRNILPYDYTRVQLKGV-AGTDYINASYIKDDhGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWP
.|||  . .| |||||..||  | ||| ||      ||| ||...    . .||.|||||..|.. || ||........||.  |.|.|  ||. |.|  
ppnvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryyp

AGEEP-QLHGNVTVTLVGSNQT---DNFIERTLLLEK----EGTE--RTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQEdgaatGPIVVHCSAGVG
.|  . .|.  .|||  ..    |  ..   . .     . .     | |.|.  | |.  |. .||.. |.. ||  ..|     .|||||||||||||
eksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkke-----kPivvhcsaGvG

RTGTFIAADMLMDAIQRSTATDYIDVagtIAKIREQRALLVQTLYQYIYLHRTV
 |..  |.    |.  .  . .|.   . ..|. |   ||. .|...|   .  
rtatlvGidyatirirenseievldi---vrelramrlkavqshlqflfllvvl

Phosphatase Spur_PTPRB5.AA PTPc_motif 4408-4515 40 9e-43 149.34 SMART 1-92 (92) Show / Hide
Range on Protein: 4408-4515
Range on HMM: 1-92/92
Sequence Identity: 40% (46 aa)

TVTHYQYLAWTDH-----GVPESTAPLVGLLRQVKVTNQEDGAATGPIVVHCSAGVGRTGTFIAADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQT
||.||.|..| ||     ||||   ... ..|.|.           |||||||||.||||||.|.||.|.          .|. .|. ..|.||. .|||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK----------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQRPGMVQT

LYQYIYLHRTVLS
. |||...| .|.
EEQYIFCYRCILE

Phosphatase Spur_PTPRB5.AA Subfamily.N_Nematode_5.PD 4260-4517 25 2.3e-40 129.8 In-house 4-257 (258) Show / Hide
Range on Protein: 4260-4517
Range on HMM: 4-257/258
Sequence Identity: 25% (67 aa)

DEYNNLPAMEKTRAvTAARQARNDDKNRYRNILPYDYTRVQLKGVAgTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEG
.|...| ..  .   |     .| .|||. ..  .| |||.|.  .  .|||||.|| |. .||.| || |||.|.| ||.|| ...  ..|...   | 
tefeklaslkpnke-tckafeknlkknrskdvkilDetrVkltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeel

GKTKCEHYWPAGEEPQLHGNVTVTL--VGSNQTD-NFIERTLLLEKEGTERTVTHYQYLAWTDHGVPESTAPLVGllRQVKVTNQEDGAATGPIVVHCSA
 .|... .    .. . .|.....   | ..... .     .| |. . .  ...|..  |...||.......   |...   ... ..  |.||....|
ketavsffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdl

GVGRTGTFIAADMLMDAIQRSTATDyidVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
.||.|||..... .. ...  . .   .. .. |||.||.  |..| || .....||  | 
GlgRagtflllsvaieqlnngkepn---ideilkkirsqRpgavesliqyasvyaavldyi

Phosphatase Spur_PTPRB5.AA Subfamily.R_Nematode_3.PD 4277-4516 28 3.3e-40 129.5 In-house 21-265 (267) Show / Hide
Range on Protein: 4277-4516
Range on HMM: 21-265/267
Sequence Identity: 28% (70 aa)

ArqaRNDDKNRYRNILPYDYTRVQLKG---VAGTDYINASYIKDDHGQkKYIATQGPL--------PNTIEHFWEMVWENQTSTIVMMTALVE---GGKT
.. ...|. ... .  ||| |||       |.|.|....  .|  | | ||.|.         .||| || |. .....||.   ||   ... || .|.
s---kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpngl-klIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeee

KCEHYWPAGEEPQLH-GNVTVT--LVGSNQTDNFIERTLLLEKE-GTERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKVTNQedgaatgPIVVHCSAGV
|  .. .|. ..|.|.   . ..  ... .||| .. | . | ||||..| .|.....||.. ... |.. |.  ..       |.|||||.|..|..|.
kcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfvekskt-------pvvVHCsdGi

GRTGTFIAADMLMDAIQRSTAtdYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSL
 |... .. | .|.    .|..  | ..|.|||  .||.....   .| |        
sRsatlaaielgyqliikskg--kldllslikelrkqRagaiqtelelafvilgilkl

Phosphatase Spur_PTPRB5.AA Subfamily.N_Nematode_egg.PD 4258-4517 24 2.1e-33 107.2 In-house 2-256 (257) Show / Hide
Range on Protein: 4258-4517
Range on HMM: 2-256/257
Sequence Identity: 24% (63 aa)

FSDEYNNLPAMEKTRAVTAARQARNDDKNRYRNILPYDYTRVQLK---GVAGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMT
.  ... |  . .  ..| | .. . .| | . .   ...||.|.   |    |.| | ..| .    ..| .| || ||| || ||....   |||.|.
lerrfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmlt

ALVEGgkTKCEHYWPAGE-EPQLH--GNVTVTLVGSNQTDNFIERTLLLEKEGTERTVTHYQYLAWTDHGVPESTAPLvGLLRQVKvtnQedgaATGPIV
 .|    .||.|||  | |.     |.. .. .. ..  . . |   |   |...   ...  .  . . .   ||  .||...   .    .. |.||.
sakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqgdvnylsdvyspl-rvlrklr---n----lskpvv

VHCSAGVGRTGTFIAADMLMDAIQRSTATDYIdVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
.  || ...|..|... .  . |   | .. |  ...| .| | |..  .|....| ||  |    
vqdilGvskaatlvaieiallsllrGpitksl-vlravvflrlrrrlsvesvllylfvyrlvlffi

Phosphatase Spur_PTPRB5.AA Subfamily.N_Fungi_PTP1.PD 4284-4380 37 1e-26 85.1 In-house 47-160 (343) Show / Hide
Range on Protein: 4284-4380
Range on HMM: 47-160/343
Sequence Identity: 37% (41 aa)

DKNRYRNILPYDYTRVQLK-----------GVAGTDYINASYIKDD------HGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEH
||||.|||||. .||.||            . . |||||.|.|          . ||||||.|||.|.. |.... .|.|...|..|| .  ||..||. 
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr

YWPAGEEPQLHGNV
|.  . .  .    
YWqegsydditvkl

Phosphatase Spur_PTPRB5.AA Subfamily.N_Nematode_eak.PD 4270-4516 24 5.1e-22 69.9 In-house 14-279 (281) Show / Hide
Range on Protein: 4270-4516
Range on HMM: 14-279/281
Sequence Identity: 24% (62 aa)

KTRAVTAARQARNDDKNRYRNILPYDYTRVQLKGV--AGTDYINASYIKDDHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHY
. .... ...  . ..||  .|.|.|.  |.|         ||||| ..  .  .||| |  .  . .  ||.|| |....||..   || .  | . |.
rllsirvtarleavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdky

WPAGEEPQLHGNVTVTLVGS-NQTDNFIERTLLLEKEGTERTVTHYQYLAWTDHGVPESTAP--L------VGLLRQVKVTNQ----------EDGAATG
|   |   .| . |.      . ...  | | |.|      | ||..  ||.  .||      || |  ... ..              .  | .. .. 
fpdktevlkyGildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallrstlkkyihtppsfa

PiVVHCSAGVGRTGTFIAADMLMDAIQRSTATDYiDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSL
|  |.|.|.  |.|.  |.      |  || |....|   | .  |. ...  ||             
p-iiqsarGsaraGvfvvidllirlidnkkknly-svedlilkvkskrihsvlvalqhsfiyeivldy

Phosphatase Spur_PTPRB5.AA Subfamily.N_Fungi_PTP1.PD 4406-4514 32 2.1e-15 47.9 In-house 212-339 (343) Show / Hide
Range on Protein: 4406-4514
Range on HMM: 212-339/343
Sequence Identity: 32% (38 aa)

ERTVTHYQYLAWTDHG---VPESTAPLVG----LLRQVKVTNQEDGAATGPIVVHCSAGVGRTGTFIAADMLMD------A-IQRSTATDYI----D-VA
.| . |.  | | .    |||  . .     |. .    .  | | . ||.||||||||||||... |.|...|.  |.     | .  .. ..|.||  
pyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlis

GTIAKIREQRALLVQTLYQYIYLHRTVL
.||.| |.|... ..|            
iivnelrkqrismvqnldqfifiYeall

Phosphatase Spur_PTPRB5.AA Family.DSP.PD 4343-4472 16 5.5e-11 33.8 In-house 129-210 (387) Show / Hide
Range on Protein: 4343-4472
Range on HMM: 129-210/387
Sequence Identity: 16% (21 aa)

WENQTSTIVMMTalveggktkcehywpageepqlhgnvtvtlvgsN------QtdnfiertlllekegtERTVTHYQYlAWTDHGVPESTApLvgLLRQV
|.. . || .|                                        .                |  ...... .. ||..|     |. . ....
kelgvtkivnlt---------------------------------ddkpqftk----------------elgikylri-pidDhnapplen-l--fekai

KVTNQEDgAATGPIVVHCSAGVGRTGTFIAADMLMD
.. .  ..| ..||| ||.||.|| |.| ..     
dfieegn-dskgvVlVHCkaGkgRsgtliiaYlmks

Phosphatase Spur_PTPRB5.AA Subfamily.PTPDC1.PD 4406-4505 31 2e-10 31.9 In-house 132-216 (229) Show / Hide
Range on Protein: 4406-4505
Range on HMM: 132-216/229
Sequence Identity: 31% (31 aa)

ERTVTHYQYlAWTDHGVPestaPLVGLLRQVKVTNQEDgaATGPIVVHCSAGVGRTGTFIAADMLMDaiQRSTATDyidvagTIAKIREQRALLVQTLYQ
.. ...|.. ...|.||.    .|  .|  ||| ..      | | ||| || ||||  ||. ..    .| || .       | ..|..|.  .||  |
rqgiyfynf-glkDygva----sleriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylvya--krltaee------aiklvrskrpksiqtreq





Phosphatase Spur_PTPRB5.AA Subfamily.CDC14.PD 4436-4482 36 7.6e-08 23.7 In-house 191-231 (258) Show / Hide
Range on Protein: 4436-4482
Range on HMM: 191-231/258
Sequence Identity: 36% (17 aa)

VKVTNQEdgaaTGPIVVHCSAGVGRTGTFIAADMLMDaiQRSTATDY
...|..     .| |.||| ||.|||||.|.. ..    .| ||.. 
leiteka----eGaiavhCkaGLGrtgtligcylikh--yrftaaet

Phosphatase Spur_PTPRB5.AA Subfamily.DSP23.PD 4416-4505 25 3.7e-07 21.7 In-house 35-116 (128) Show / Hide
Range on Protein: 4416-4505
Range on HMM: 35-116/128
Sequence Identity: 25% (23 aa)

AWTDHGVPESTAPLVGLL-RQVKVTnQEDGAATGPIVVHCSAGVGRTGTFIAADMLmdAIQRSTATDyidvagTIAKIREQRALLVQTLYQ
...  ..|. . | .  . | |..  .|  .  ... |||  |.|||||..|  ..  . .. .| |      .|| .|..|   ..||  
tlrridipdfcPPaleqvarlvriv-eeaekkeeavgvhcalGlGrtGtllacylv--keeglaadd------aiaevrkrrkGsietveq

Phosphatase Spur_PTPRB5.AA Subfamily.PTEN.PD 4450-4478 48 8.1e-06 16.8 In-house 97-125 (305) Show / Hide
Range on Protein: 4450-4478
Range on HMM: 97-125/305
Sequence Identity: 48% (14 aa)

IVVHCSAGVGRTGTFIAADMLMDAIQRST
..||| || ||||. |.| .|.  |..|.
vavHCkaGkGRtGvmicayLlksgikksa

Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPRB5.AA Protein None 4520 None Fasta, JSON
Spur_PTPRB5.NA RNA None 13560 None Fasta, JSON
Spur_PTPRB5.AA.PD_4257-4518 Protein Phosphatase Domain None 262 None Fasta, JSON