Gene Spur_PTPRB6
Spur_PTPRB6
Species: S.purpuratus
Alias: hmm91036, Spur_hmm256819, Spur_PTPRB6
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Spur_PTPRB6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Nematode_4.PD | 83-185 | 26 | 7.1e-16 | 49.3 | In-house | 5-104 (264) | Show / Hide |
Range on Protein: 83-185 Range on HMM: 5-104/264 Sequence Identity: 26% (27 aa) LKAEKIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAAlaDDSDTDYINANYIPGYnSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLV |. ...| . . . |... ... ...|| | | | ||| |... .....||||. |..|.| |... |....||| .|. ltrdfvkgkappnvtasaseknsdknryadilcidetrvvlkn--rdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdli EKG |.| eeg |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.RB.PD | 103-188 | 70 | 6.3e-44 | 141.2 | In-house | 25-110 (261) | Show / Hide |
Range on Protein: 103-188 Range on HMM: 25-110/261 Sequence Identity: 70% (61 aa) EKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR .. | . ... .|||||||||.|.|||||||||||||||||||..|.|||||.||||.|||.||||.||||||||||||||.. vnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkek |
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| Phosphatase | Spur_PTPRB6.AA | Y_phosphatase | 113-187 | 45 | 6.8e-34 | 120.35 | Pfam | 10-86 (243) | Show / Hide |
Range on Protein: 113-187 Range on HMM: 10-86/243 Sequence Identity: 45% (35 aa) VILNEHSRVKLAALADDSDTDYINANYIPG-YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK-V .. ..|.|||| . .| |.||||||||.| |..|... ..|||.| |..| |||.|. |...||||....|.|. . IPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDE |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.RG.PD | 95-186 | 45 | 2.3e-31 | 100.1 | In-house | 18-109 (264) | Show / Hide |
Range on Protein: 95-186 Range on HMM: 18-109/264 Sequence Identity: 45% (41 aa) IMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK .. ..|| . ... |.|||||. |.. ..|||||.|| ||. .|... ||||. |..| ||||||....||||||.|.|||. eaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgr |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.R_Anemone_2.PD | 113-187 | 48 | 2.4e-31 | 100.2 | In-house | 36-110 (262) | Show / Hide |
Range on Protein: 113-187 Range on HMM: 36-110/262 Sequence Identity: 48% (36 aa) VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV .. ...|||| |... ..||||||||.||.. ....|.|.||| |..|.|||.||.....||||||..|.||. ilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergka |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.R_Sponge_2.PD | 112-186 | 48 | 1.4e-29 | 94.3 | In-house | 33-106 (262) | Show / Hide |
Range on Protein: 112-186 Range on HMM: 33-106/262 Sequence Identity: 48% (36 aa) KVILNEHSRVKLAAlADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK ... ..|||.| . . .|.|||||... ||... ..| ||||. ||.|.|||.|| |.|.|||||.|.|.|| eilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Choan_1.PD | 113-188 | 42 | 4e-29 | 92.7 | In-house | 35-110 (262) | Show / Hide |
Range on Protein: 113-188 Range on HMM: 35-110/262 Sequence Identity: 42% (32 aa) VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR .. ...|||.. ....|||||||..|||....|..|.|||.| .....|.|.||.| |.|||.|. .|.||.. ivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N9.PD | 112-187 | 49 | 2.5e-28 | 90.2 | In-house | 34-109 (275) | Show / Hide |
Range on Protein: 112-187 Range on HMM: 34-109/275 Sequence Identity: 49% (37 aa) KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV |. ...||||| | .|. .||||||.. ||. .. |.| ||||. ||.| |||.||... .||| |..||.|.. dvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrl |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.RA.PD | 96-186 | 39 | 9.9e-28 | 88.2 | In-house | 19-109 (266) | Show / Hide |
Range on Protein: 96-186 Range on HMM: 19-109/266 Sequence Identity: 39% (36 aa) MKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK .. ..|| . ... ...||| |. . ..||||| .| ||. .|.|.|||. ||.|.||||||.|.. |||||.| |... lrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerke |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.R_Anemone_1.PD | 101-186 | 42 | 5.4e-26 | 82.7 | In-house | 22-107 (258) | Show / Hide |
Range on Protein: 101-186 Range on HMM: 22-107/258 Sequence Identity: 42% (36 aa) HEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK ..| . . . ... .|||| | .| .|...||||| |. ... |.|.|.|.||. ||.| |||.|..|...|||||.|.|.| kaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegek |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Choan_2.PD | 113-187 | 46 | 9.9e-26 | 81.4 | In-house | 30-105 (266) | Show / Hide |
Range on Protein: 113-187 Range on HMM: 30-105/266 Sequence Identity: 46% (35 aa) VILNEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV .. . ..||.|. | .|| | ||||||..|.. ......| .|||| |. . ||||||.|.. |||.|.|.|||. iLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N12.PD | 110-188 | 47 | 1.2e-25 | 81.1 | In-house | 38-116 (270) | Show / Hide |
Range on Protein: 110-188 Range on HMM: 38-116/270 Sequence Identity: 47% (36 aa) TGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR .. ..|||.| .. . ||||||.| | ... |..|.||||| |.|| |||||||...|.||. ..|| || . ykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.RK.PD | 102-187 | 36 | 1.4e-25 | 80.9 | In-house | 27-112 (267) | Show / Hide |
Range on Protein: 102-187 Range on HMM: 27-112/267 Sequence Identity: 36% (32 aa) EEKPAAQCTGKVILNEHSRVKLAALADDsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQL-VEKGKV ... . . ..... ..|.|.| .. .| ..|||||..| .|. |..|.. ||||. || |.||........ |||||.| ||.|.| drnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrv |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N5_RR.PD | 112-186 | 46 | 1.4e-25 | 81.1 | In-house | 31-107 (265) | Show / Hide |
Range on Protein: 112-186 Range on HMM: 31-107/265 Sequence Identity: 46% (36 aa) KVILNEHSRVKL-AALADDSDTDYINANYIPGYNS-PREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK ... ||.||| | .. ..|.|..||||||| ||. . ..| ||||| |..|.||||.......|||||.| |. . tilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanr |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.R_Ecdysozoa.PD | 98-186 | 37 | 4.8e-25 | 79.1 | In-house | 21-109 (269) | Show / Hide |
Range on Protein: 98-186 Range on HMM: 21-109/269 Sequence Identity: 37% (32 aa) CDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK ...| ... .. ||||. . . |.|||||..| ||. ..|.| |.|. .|..|.||||.|.. .||||..||| . vsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknr |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N13.PD | 99-188 | 38 | 1.2e-21 | 68.4 | In-house | 21-107 (259) | Show / Hide |
Range on Protein: 99-188 Range on HMM: 21-107/259 Sequence Identity: 38% (35 aa) DQHEEKPAAQCTGKVILNEHSRVKLAALADdsdtdYINANYIPG--YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR ...|. .. .|. ...|||| . . ||||..| . |..||||||| ||.|.|.|.||.|...|.|.|. .|||||. gkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.RC.PD | 128-183 | 52 | 1.6e-21 | 67.8 | In-house | 69-124 (288) | Show / Hide |
Range on Protein: 128-183 Range on HMM: 69-124/288 Sequence Identity: 52% (29 aa) DDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE . ..|||| .| .| |. ..| |||| ||||.||||.|.|. .|||||.| | seegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelke |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N3.PD | 117-187 | 48 | 2.9e-21 | 66.8 | In-house | 39-109 (261) | Show / Hide |
Range on Protein: 117-187 Range on HMM: 39-109/261 Sequence Identity: 48% (36 aa) EHSRVKLaalaDDSDTDYINANYI----PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV .. |||| ..|.||||||||. |. . ..|.||||. |. |.|.|.||.|...|||||.|||.|.| datrvkl----kesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrv |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N14.PD | 90-187 | 34 | 3e-20 | 63.5 | In-house | 12-110 (275) | Show / Hide |
Range on Protein: 90-187 Range on HMM: 12-110/275 Sequence Identity: 34% (33 aa) AMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDsDTDYINANYIPGY--NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV .| .... . .| . . .|. |..||.|.. .. .|.|||| | . |.....||||. || |.|.|.||.....|||||.|.|| kredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgke |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N6.PD | 113-186 | 38 | 7.4e-20 | 62.3 | In-house | 49-136 (295) | Show / Hide |
Range on Protein: 113-186 Range on HMM: 49-136/295 Sequence Identity: 38% (34 aa) VILNEHSRVKLAAL-ADDSDTDYINANYI--------PGYN--SP---REFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK .. .|.||.| . ...|||||||| | | | ....| ||.|. || | |||.|.... .|||.|. ||.|| ilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N1.PD | 112-187 | 38 | 7.5e-20 | 62.4 | In-house | 36-107 (268) | Show / Hide |
Range on Protein: 112-187 Range on HMM: 36-107/268 Sequence Identity: 38% (29 aa) KVILNEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV | .|||.|| ..|.|||||. . . |... ||||| |.| |.|.||... ..|| ..|||... dvspydhsrikle----radvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqi |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N23.PD | 102-187 | 39 | 6.7e-19 | 59.0 | In-house | 101-187 (350) | Show / Hide |
Range on Protein: 102-187 Range on HMM: 101-187/350 Sequence Identity: 39% (35 aa) EEKPAAQCTgKVILNEHSRVKLAALA-DDSDTDYINANYIPGYN--SPrEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV | | | . ....|||| .. . ||||| |. || .|.| |||.. |. | | |.||...|.|||||. ||..| egsGqqqgt-pdsrhdpnrvklqqstqpgqqddyinatylkeltpmsP-pfiatqgPiastlaDFWlmvweqqssviVmltkevegnkl |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.RN.PD | 101-186 | 40 | 8.5e-18 | 55.4 | In-house | 24-110 (264) | Show / Hide |
Range on Protein: 101-186 Range on HMM: 24-110/264 Sequence Identity: 40% (35 aa) HEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYnSPRE--FMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK .|. . . .|. .|||||| . | ....||||| | ||. ..|.||||. |. |.|.|.||. . .||.||.| |.| aeknvkknrskavlpydhsrvklkeeasaeksdyinasaildh-dprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegv |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Nematode_1.PD | 113-187 | 41 | 9.4e-17 | 52.1 | In-house | 35-107 (265) | Show / Hide |
Range on Protein: 113-187 Range on HMM: 35-107/265 Sequence Identity: 41% (31 aa) VILNEHSRVKLAAlaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV | ...||||| . . .||| |||. |. |. .|.|| |..|.| |. .| |||| .|.||||. vgcldknrvklae--eplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Nematode_egg.PD | 108-184 | 38 | 2e-16 | 51.1 | In-house | 29-106 (257) | Show / Hide |
Range on Protein: 108-184 Range on HMM: 29-106/257 Sequence Identity: 38% (30 aa) QCT-GKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK .. .| .| ||||| |.| ||.. | ||. .| || ||.|.|||....| ||||| .| karskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.R_Nematode_2.PD | 125-186 | 42 | 3.1e-16 | 50.3 | In-house | 48-108 (261) | Show / Hide |
Range on Protein: 125-186 Range on HMM: 48-108/261 Sequence Identity: 42% (26 aa) ALADDSDTDyINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK . |. .. | ||..| . |. |.| |||| |..| | |. .| ||||.| ||| | vivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekek |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Fungi_PTP1.PD | 116-185 | 38 | 7.1e-15 | 45.7 | In-house | 57-140 (343) | Show / Hide |
Range on Protein: 116-185 Range on HMM: 57-140/343 Sequence Identity: 38% (32 aa) NEHSRVKLA--------ALADDSDTDYINANYIPGY------NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG ||||||| | |||||||. |. ..| |.||| ||||....| . | .|..||..|| . YehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdveln |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Nematode_5.PD | 87-180 | 26 | 1.5e-14 | 44.8 | In-house | 8-97 (258) | Show / Hide |
Range on Protein: 87-180 Range on HMM: 8-97/258 Sequence Identity: 26% (25 aa) KIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVklaaLADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ |..... ...|.. |. . .| .....|| | | .||||..| .. .... | ||| |. |.|||. ..| .|.|.. klaslkpnketckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllve |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N_Nematode_6.PD | 125-186 | 47 | 1.9e-13 | 41.4 | In-house | 42-102 (253) | Show / Hide |
Range on Protein: 125-186 Range on HMM: 42-102/253 Sequence Identity: 47% (29 aa) ALADDSDtDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK |||| | || ||.. || .. .|.|| ||....|.|| . . |||| .|||||| kladded-fyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgk |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.N20.PD | 131-187 | 43 | 2e-12 | 38.2 | In-house | 48-106 (257) | Show / Hide |
Range on Protein: 131-187 Range on HMM: 48-106/257 Sequence Identity: 43% (25 aa) DTDYINANYIPGYNSPREF--MACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV |||||.|| | |. .| |||| |.||.|.|. |... .| |.|. .| | . skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggii |
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| Phosphatase | Spur_PTPRB6.AA | Subfamily.R_Nematode_3.PD | 96-183 | 25 | 4e-10 | 30.4 | In-house | 14-109 (267) | Show / Hide |
Range on Protein: 96-183 Range on HMM: 14-109/267 Sequence Identity: 25% (25 aa) MKCDQHE-EKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSpREFMACQGPL--------PGTVDDMWRMIWEKKTSIIVMLTQLVE .| .... .| . . .|.|.|..||.| |.|.||.. |. .. |.|. |.. | || ..|. ..||| . || kknatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpng-lklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfve |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Spur_PTPRB6.AA | Protein | None | 188 | None | Fasta, JSON |
| Spur_PTPRB6.NA | RNA | None | 564 | None | Fasta, JSON |
| Spur_PTPRB6.AA.PD_87-188 | Protein Phosphatase Domain | None | 102 | None | Fasta, JSON |