• Phosphatome.Net

Gene Spur_PTPRB7

Spur_PTPRB7
Species: S.purpuratus
Alias: hmm91817, Spur_hmm270333, Spur_PTPRB7
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RB
Protein domain

Protein domains of Spur_PTPRB7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Spur_PTPRB7.AA PTPc 8-256 32 2e-95 324.21 SMART 1-308 (308) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-308/308
Sequence Identity: 32% (104 aa)

GFSDEYNSLPAMEKIR---------AVTVARNARND--DKNRFR-NILPYDYNRVQLKGEVG-------NDYINASYIADDQGNRKYIATQGPLPNTIDH
||..|...|..|.. .           |.|.   |   ||||.. .|..||..|| || . |       .|||||.||  . ....||.||||||.||..
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWEMVWETKASTIVMMTALVEG--------GKTKCEHYWPTGQKPHLHGNVTVTLVGSKQTE-HFIQRTLLIGKKG----------TELTVTHYQYLAWT
|| |||. | ..|||.. ..|.        |. ||..|||    |  .|. |||..  .... ... ||. . ..|           ..|||||.| .| 
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DHGVPASTAPLVALLYQVKMTSQEDGAL----------------TGPIIVHCSAGIGRTGTFIAADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQT
||||| |. .. ... ||. ...  .                  ||||.||||||.||||||.|.|.... |..      .|| ..| ..|.||  .|||
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN------VDIFQIVKMMRNQRPGMVQT

-------------LVR
             ...
EEQYIFCYRCILEYIK
Phosphatase Spur_PTPRB7.AA Subfamily.RB.PD 9-255 49 3.9e-103 335.9 In-house 2-247 (261) Show / Hide 
Range on Protein: 9-255
Range on HMM: 2-247/261
Sequence Identity: 49% (124 aa)

FSDEYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQL---KGEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMT
||.||..| ...| .||. |..| |..||||.||||||..||.|   | | ..|||||.|| . . .|.|||||||||.|.|.||.||||.|.|.|||.|
fseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

ALVEGGKTKCEHYWPTGQKPHLHGNVTVTLVGSKQTEHFIQRTLLIGKKGTELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDgALTGPIIVHC
 |||.||.|||.|||. ..|.|.|...|||. .|...... |.. | |. .. .|..|....|.||||| .|..|......|. . ... | ..||.|||
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekk-askkPivvHC

SAGIGRTGTFIAADMLMNAIQRstaTDYIDIAGTVAKLREQRTSLVQTLV
|||.|||||||| |.|..||..   .||.|..|.||.|||.|..||||..
saGvGRtGtfialdrllqaiee---ndyvdvfgvvaelReeRnllvqtek
Phosphatase Spur_PTPRB7.AA Y_phosphatase 33-254 38 2.8e-98 337.62 Pfam 1-231 (243) Show / Hide 
Range on Protein: 33-254
Range on HMM: 1-231/243
Sequence Identity: 38% (92 aa)

NDDKNRFRNILPYDYNRVQLK---GEVGNDYINASYIAD-DQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGK-TK-CEHYWPT--GQK
| .|||...|..||..|| |.   |. . |||||.||   .. ...||.||||.|.||..|| |||. | ..|||.. ..|.|.  | |..|||.   . 
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

PHLHGNVTVTLVGSKQTEHFIQRTLLIGKKGT----ELTVTHYQYLAWTDHGVPAS-TAPLVALLYQVKMTSQEDGALTG--PIIVHCSAGIGRTGTFIA
|  .|. .||.|  ....... ||. . . |.    ..|||||.|..|.||||| | . ... .. ||.  ..      |  ||.||||||.||||||.|
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP--NPDHGCPPIVVHCSAGCGRTGTFCA

ADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQTL
.|...  ....      || ..| ..|.||  .|||.
IDIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTE
Phosphatase Spur_PTPRB7.AA Subfamily.N_Choan_1.PD 8-255 38 3.6e-76 247.5 In-house 1-248 (262) Show / Hide 
Range on Protein: 8-255
Range on HMM: 1-248/262
Sequence Identity: 38% (97 aa)

GFSDEYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQL---KGEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMM
||  ||..| ....  . | ...  |  |||..||  ||  ||..   . .  .|||||....  .|...|||||||.|.....||.||||.|.|.|||.
GfieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmv

TALVEGGKTKCEHYWPTGQKPHLHGNVTVTLVGSKQTEHFIQRTLLI-GKKGTELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDGAltGPIIV
|. .|.|| || .||| ...    |.|||. . .......|.|.. .  ..| . .|.. .|.|| ||||||.|. |.    .|. .....     |...
treieagklkChryWPdenselklgdvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk--aplvi

HCSAGIGRTGTFIAADMLMNAIQrsTATDYIDIAGTVAKLREQRTSLVQTLV
|||||.|||||.|| | |..|..  . .. .|.  .||.||..|. .|||||
hCsaGvGrtGtyialDrlvkave--ekaealdvkavvaelrkernlmvqtlv
Phosphatase Spur_PTPRB7.AA Subfamily.R_Anemone_2.PD 9-253 43 8e-75 243.3 In-house 2-246 (262) Show / Hide 
Range on Protein: 9-253
Range on HMM: 2-246/262
Sequence Identity: 43% (108 aa)

FSDEYNSL-PAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQLK---GEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMM
.| ||. | .. |.   .. | .  |  |||. |||.||  ||.|.   ||.| |||||.||   . ...|||||.|||.||. || |||| ....|||.
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TALVEGGKTKCEHYWPTgQKPHLHGNVTVTLVGSKQTEHFIQRTLLIGKKGT--ELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDGAltGPII
| ..| ||.|...|||  .... .|...|.|  ........ |.. . ....  | .|  ..| .|.|.|||.|.| |..|. ||. . || ||  |||.
tqeeergkakvhryWPs-kgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesga--gpiv

VHCSAGIGRTGTFIAADMLmnaIQRSTATDYIDIAGTVAKLREQRTSLVQT
||||||.||||.||| |.|   ..|  |   .|. .|| .|||||  .|||
vhcsaGvGrtGvfiavdil---lerikaealvdvfqtvkqlreqrnlmvqt
Phosphatase Spur_PTPRB7.AA Subfamily.N12.PD 19-253 41 1.7e-73 238.6 In-house 18-254 (270) Show / Hide 
Range on Protein: 19-253
Range on HMM: 18-254/270
Sequence Identity: 41% (98 aa)

MEKIRAVTVARNARNDDKNRFRNILPYDYNRVQLKG---EVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKC
.||. . ..... .|  |||...|||||..||.|.    | |.|||||..|   .|. .|||.|||||.|.| || |.||.. . .||.  .|| ||.||
aekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkC

EHYWPTGQKPHL-HGNVTVTLVGSKQTE-HFIQRTLLIGKKGTELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQedgALTGPIIVHCSAGIGRTG
|.|||  .. .| .|...|||   |...  |. ||| . ..... .|. ..| || |||||.|. .|..|. .|. . .   .|..||||||.||||| |
eryWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqe---sedaPlvvhCsaGvGrtG

TFIAADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQT
| |.  ..... . .. .|.   |..||.||..||||   
tiiaidyvrellkaekipeeldvfdlvlelrkqraalvqt
Phosphatase Spur_PTPRB7.AA Subfamily.R_Sponge_2.PD 10-255 38 5.9e-73 237.1 In-house 3-248 (262) Show / Hide 
Range on Protein: 10-255
Range on HMM: 3-248/262
Sequence Identity: 38% (96 aa)

SDEYNSLPAMEKIrAVTVARNARNDDKNRFRNILPYDYNRVQLKG--EVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTAL
.|..|..  ...  .. |..  |  ||||..||||| .||.|.   . . ||||||..   . .  ||||||||..|.. || |||| | |||||.| |.
eeeeksveketef-slsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnl

VEGGKTKCEHYWPTG-QKPHLHGNVTVTLVGSKQTEHFIQRTLLIGKK---GTELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDGAltGPIIV
| || ||..|||.  ..    |...|||. .......| |.| . |.   . |..||.....||..|.||.....|..|. .|. . ...|   ..|.|.
eengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgn--kaitv

HCSAGIGRTGTFIAADMLMNAIqrsTATDYIDIAGTVAKLREQRTSLVQTLV
||.|.|||||||| |.... .    | . ||.  ....|| .|. |||. . 
vCsdgvgrtGtfialdsvlerl---kaeeeidvfevlktlrtkriglvqdaa
Phosphatase Spur_PTPRB7.AA Subfamily.N6.PD 8-254 38 1.2e-72 236.3 In-house 13-280 (295) Show / Hide 
Range on Protein: 8-254
Range on HMM: 13-280/295
Sequence Identity: 38% (102 aa)

GFSDEYNSLP--AMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQLKGE----VGNDYINASYI---------ADDQG----NRKYIATQGPLPNTIDH
||..|...|   ..||    . .. ..| .|||..||||.| .|| ||      .|.|||||.||         .. ..     ..||||||.|..|.  
gfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsd

FWEMVWETKASTIVMMTALVEGGKTKCEHYWPTGQKPHLHGNVTVTLVGSKQTEHFIQRTLLIGKK---GTELTVTHYQYLAWTDHGVPASTAPLVALLY
||.|||. ..  |||.|  || || || .|||. .. . .|..||| .  |.|.... |.... .|    .. .. .|.. || |||||...  .. .| 
FWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfle

QVKMTSQEDgALTGPIIVHCSAGIGRTGTFIAADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQTL
.|.....|    .|||.||||||||||||||  |.... |..| .   |||  .. ..|.||. |||| 
dvnkkqeel-ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqte
Phosphatase Spur_PTPRB7.AA Subfamily.N13.PD 10-253 41 1.2e-72 236.0 In-house 3-243 (259) Show / Hide 
Range on Protein: 10-253
Range on HMM: 3-243/259
Sequence Identity: 41% (101 aa)

SDEYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQLKGEVGndYINASYIADD--QGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTAL
..|.. |  .  .  ..|.....| ||||.||.||||  ||.|..| |  |||||.|     . . .|||.|||||.|.. || |||| ||.|.|.|  .
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtle

VEGGKTKCEHYWPTGQ--KPHLHGNVTVTLVGSKQTEHFIQRTLLIGKKGT--ELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQeDgalTGPIIV
|.|| ||. |||  .  | .... ..|.|.. .. . | .|.| . .. .     |.| .. .| |||||.|.|.|| .. .|.. |   .|||.|||||
kekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-d---agPivv

HCSAGIGRTGTFIAADMLMNAIQRSTatdYIDIAGTVAKLREQRTSLVQT
||||.|..|. |.... |.| .    .|.  .| |||||| ..|||    
hcsaGiGrsGvlitidvvlglierdk---efdvkeivrklreqrqgvvqt
Phosphatase Spur_PTPRB7.AA Subfamily.R_Anemone_1.PD 9-254 36 5.4e-71 230.8 In-house 2-243 (258) Show / Hide 
Range on Protein: 9-254
Range on HMM: 2-243/258
Sequence Identity: 36% (90 aa)

FSDEYNSLPAMEKiRAVTVARNARNDDKNRFRNILPYDYNRVQLKG---EVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMT
...|.. |  ...   . |||.|.| .|||. .|...|  || |.    .   |||||||.   .. |..||||.||..|.. |||||. |...|||.| 
yaaefqrlkeike-eekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLt

ALVEGGKTKCEHYWPTgqKPHLHGNVTVTLVGSKQTEHFIQRTLLIGKKGTE--LTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDgalTGPIIV
|.|| |.||..|||.  ... .|...|.|  ...  ..| |||.. ||...   .|..|... |.|.|||  .. ...|. .|. .|...   . |..||
nliegekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslag---arpvvv

HCSAGIGRTGTFIAADMLMNAIQRStatDYIDIAGTVAKLREQRTSLVQTL
||||.||||.|.. | ... ....     .||  .| ..||.|. .|||  
hCsaGvgRtGaflvidamleqakke---kvvDifnyvkairedrphmvqtk
Phosphatase Spur_PTPRB7.AA Subfamily.N3.PD 23-254 40 2.4e-69 225.0 In-house 16-246 (261) Show / Hide 
Range on Protein: 23-254
Range on HMM: 16-246/261
Sequence Identity: 40% (95 aa)

RAVTVARNARNDDKNRFRNILPYDYNRVQLKGEVGnDYINASYIADDQGN----RKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHY
|...|| ..| .|||.|.|||||  ||.|| .   |||||.|.  .        .||||||||..|  .||.|||| |...|||.| ||| |..|| .||
laisaarkpenlaknryrdilpydatrvklkeset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqy

WPTGQKPHLHGNVTVTLVGSKQTEHFIQRTLLIGKKG--TELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSqedGALTGPIIVHCSAGIGRTGTFI
|. ..   .|...|..  ...|. .. | |.. .|    | .... |||||.||||| ..| .. .. .|. .     . . |..||||||||||| .|.
WPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr---sgkeePvvvhCsaGigrtGvli

AADMLMNAIQRSTATDYIDIagtVAKLREQRTSLVQTL
 .. .  |... .   .||   | ..|.||..||||  
lletalalieaaepvypldi---vrtmrdqramlvqtv
Phosphatase Spur_PTPRB7.AA Subfamily.N_Choan_2.PD 20-255 35 2.2e-67 218.5 In-house 8-252 (266) Show / Hide 
Range on Protein: 20-255
Range on HMM: 8-252/266
Sequence Identity: 35% (89 aa)

EKIRAVTVARNARNDDKNRFRNILPYDYNRVQLKGEVG---NDYINASYIA-DDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKC
..    ..   |||   ||...|||    ||.|. .       |||| |..  |. ..||||..||||.|. .|| |.||.|...|||.| |.| |..||
qevseeaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkC

EHYWPTGQKPHL---HGNVTVTLVGSKQTEHFIQRTLLIGKKGTELTVTHYQYLAWTDHGVPASTA------PLVALLYQVKMTSQEDGALTgPIIVHCS
| |||. .| ..   .|...|. . ....| .|.. | . |||.. ...|..| .| ||||| ..        |...| .|. ...|    . |..||||
erYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkae-PllvHcs

AGIGRTGTFIAADMLMNAIQRSTATDYIDIagtVAKLREQRTSLVQTLV
||.|||||.|| |. ........  | . |   ...||..|. |||. .
aGvgRtGtliaiDiavrlLeetkkvdvlai---ieelRkdRmalvqhpe
Phosphatase Spur_PTPRB7.AA Subfamily.RA.PD 9-255 35 7.2e-67 217.1 In-house 2-252 (266) Show / Hide 
Range on Protein: 9-255
Range on HMM: 2-252/266
Sequence Identity: 35% (92 aa)

FSDEYNSLPAMEKI-RAVTVARNARNDDKNRFRNILPYDYNRVQL---KGEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMM
. .|...|....     . .|    | .|||. .|||||..|| |   .||   ||||||.|   .   |.||.|||. .|.. || |.|| |..||||.
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

TALVEGGKTKCEHYWPTgQKPHLHGNVTVTLVGSKQTEHFIQRTLLIGKKG------TELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDGAlt
| | | ...||  |||. .    .|...|..  .. .|..  | .|. ...      ..  |. . . .| . ||||..  .. || .|| . |. ..  
telkerkeekcaqywpd-eGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsan--

GPIIVHCSAGIGRTGTFIAADMLMNAIQrstATDYIDIAGTVAKLREQRTSLVQTLV
 ||.||||||.|||||||. | ... ..   | . .|. ..| .|| ||. .|||| 
hpivvhcsaGvGrtGtfivldavlervk---aerkldvfeavkrlrlqrpqmvqtle
Phosphatase Spur_PTPRB7.AA Subfamily.N5_RR.PD 11-253 33 1.6e-65 212.6 In-house 4-249 (265) Show / Hide 
Range on Protein: 11-253
Range on HMM: 4-249/265
Sequence Identity: 33% (85 aa)

DEYNSLPAMEKIRAVTVARnarNDDKNRFRNILPYDYNRVQLKGEVG----NDYINASYIADDQG-NRKYIATQGPLPNTIDHFWEMVWETKASTIVMMT
.|. .||.  . . ..|..   .  |||...||| .  || |. | .     .|||| ||   .. .. |.||||||||||. ||.|....... |||.|
keflelPlnfsqeelevfg---sqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmlt

ALVEGGKTKCEHYWPTGQKP---HLHGNVTVTLVGSKQTEHFIQRTLLIGKKGT-ELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDGALTGPI
 | |  ..||..|.|. ..    . .|.| .. .. ......  |.|.. .    | .|.|| | .| || .| .. .|. |. .|. . .|. | ..|.
klkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPv

IVHCSAGIGRTGTFIAADMLMNAIQRstaTDYIDIAGTVAKLREQRTSLVQT
.||||||||||| |||... .. ...   .  .|. ..|..|| .|  .|||
vvhcsaGiGrtGcfiaisiavrqlre---eivvdvlkivcnlrldrGGmvqt
Phosphatase Spur_PTPRB7.AA Subfamily.N9.PD 8-253 38 1.4e-64 209.7 In-house 1-259 (275) Show / Hide 
Range on Protein: 8-253
Range on HMM: 1-259/275
Sequence Identity: 38% (97 aa)

GFSDEYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQLK---GEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMM
| | || .. ...    .....   | .|||. ..| ||  ||.|.   ..   |||||...   . .. .|||||||..|.. || |||| ...|||.|
GlskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmt

TALVEGGKTKCEHYWPTG-QKPHLHGNVTVTLVGSKQTEHFIQRTLLIG--KKGTELTVTHYQYLAWTDHGVPASTAPLVALLYQVK---------MTSQ
 .|| |. || .|||.. .. . .|...|. |. ...|.. .|.| |   |.. . .|||.|.|.| |.||| |.| |. .| .|...... | |.| ||
trvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde

EDGALTG-PIIVHCSAGIGRTGTFIAADMLMNAIQrstATDYIDIAGTVAKLREQRTSLVQT
.||||||||||||||. |. .. ..    .. .|.  || .||.||.  .||          
skghlsgPPivvhcsaGiGrtGtfitldiclarle---evgtvdvvetvkllrtqrafsiqt
Phosphatase Spur_PTPRB7.AA Subfamily.RG.PD 9-253 33 6.6e-64 207.4 In-house 2-248 (264) Show / Hide 
Range on Protein: 9-253
Range on HMM: 2-248/264
Sequence Identity: 33% (83 aa)

FSDEYNSLPAMEKIR-AVTVARNARNDDKNRFRNILPYDYNRVQLKGEVG---NDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMM
...... .  ...    .. ... .|  |||  ||....  ||.|..  |   .||||||||   . ...||.|||||..||. || |.|| .|..|||.
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TALVEGGKTKCEHYWPTGQKPHLHGNVTVTLVGSKQTEHFIQRTLLIGK----KGTELTVTHYQYLAWTDHGVPASTAPLvalLYQVKMTSQEDGALTGP
| |.| |. ... |||. ..|   ....|||.  ....... |.... .    |..| .|..|.|  | |.|.| ||..    | .||..   . .|||.
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfv---lifvkkeeaankeeaGP

IIVHCSAGIGRTGTFIAADMLMNAIQRStatDYIDIAGTVAKLREQRTSLVQT
||.||| ||.||.|| | |.. ...    . ... ... ..| .|  ||.|  
ivvhdsaGvgragtyialdtllqqleke---eavnvyqvlklirakRpglvtt
Phosphatase Spur_PTPRB7.AA Subfamily.R_Ecdysozoa.PD 9-254 36 2e-63 205.6 In-house 2-254 (269) Show / Hide 
Range on Protein: 9-254
Range on HMM: 2-254/269
Sequence Identity: 36% (94 aa)

FSDEYNSLPAM-EKIRAVTVARNARNDDKNRFRNILPYDYNRVQLKG---EVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMM
.  ||..|.|  |  .  .|. .  |  |||...| ..| .||.||    .   ||||||.|   . ..|.|| |.|. .||. || |..| .  .|||.
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TALVEGGKTkCEHYWPTGQKPHlHGNVTVTLVGSKQTEHFIQRTLLIGKKG-----TELTVTHYQYLAWT-DHGVPASTAPLVALLYQVKMTSQED--GA
. | |  .  |..|||  .. . .|.. |.|| .......|.|.| . ||.      .  |. |.| .||  || ..  |. |..||.   . .      
snlteknrk-cakyWpiedevq-ygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

LTGPIIVHCSAGIGRTGTFIAADMLMnaiQRSTATDYIDIAGTVAKLREQRTSLVQTL
.||.|||||| ||.|.|.| |.|.   |.  | | .||  || |||.||. ||| |  
srsPivvhCsaGvgrsgifvaldlll---qqlkaedkvdifetvkkLrsqrnllvqsl
Phosphatase Spur_PTPRB7.AA Subfamily.RK.PD 9-254 33 3.7e-63 204.7 In-house 2-252 (267) Show / Hide 
Range on Protein: 9-254
Range on HMM: 2-252/267
Sequence Identity: 33% (86 aa)

FSDEYNSL---PAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQLK---GEvGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIV
. .|...|       .   . .| . || .|||. .||.||  .|.|.   |.  .|||||..|   .  ...|.|||||..|.  || .|......|||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MMTAL-VEGGKTKCEHYWPTGQKpHLHGNVTVTLVGSKQTEHFIQRTLLIGK--KG--TELTVTHYQYLAWTDH-GVPASTAPLVALLYQVKMTSQEdgA
.| | || |. || .|||   . . .|.. |.|| ..  . ...|.. . |  .|     .| ..|.|.|... .|| |   |..|..||....|  .  
mlteldvevgrvkClkyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee--e

LTGPIIVHCSAGIGRTGTFIAADMLMNAIQRStatDYIDIAGTVAKLREQRTSLVQTL
|.|.|||.|| ||.||||| |.... |.|    . .|.  .| .||.... .|.|   
eeGrivvhClaGaGrsGtfiaidivlemiere---gvvdvfnavktlrnrkvnmvete
Phosphatase Spur_PTPRB7.AA Subfamily.N1.PD 24-253 34 1.3e-62 203.2 In-house 19-252 (268) Show / Hide 
Range on Protein: 24-253
Range on HMM: 19-252/268
Sequence Identity: 34% (82 aa)

AVTVARNARNDDKNRFRNILPYDYNRVQLKGEvGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWPTGQ
...|.  .| ..||.|.. |||. |..|. .  .|||||| .  .. .|.|| ||||||.|.||||.|||| .. ...|.  .|| ...|| .|||....
etreaklpenrglnryrdvspydhsriklera-dvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqee

KP-H--LHG-NVTVTLVGSKQTEHFIQRTLLIGKKGT--ELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEdGALTGPIIVHCSAGIGRTGTFIA
     |.  . .|.|.  .....|..|.| .  . |    ...|..|  |.| ||| | | .. .|..|. .        ||...||||||||.||.   
eeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsL-ssdvgpavihCsagigrsgtlsl

ADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQT
| ..  |..   .. .||   . .||..|  |.|| 
vdtclveiektgdlnavdikkvLlelRkyRvGLiqt
Phosphatase Spur_PTPRB7.AA Subfamily.RC.PD 9-254 33 3.1e-60 195.4 In-house 2-273 (288) Show / Hide 
Range on Protein: 9-254
Range on HMM: 2-273/288
Sequence Identity: 33% (92 aa)

FSDEYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQL----------------------KGEVGNDYINASYIADDQGNRKYIATQGPLPNTI
.  |...|| .   |.. .||.  | .|||. ..||||||||.|                      ..| | .|||||.|   .  .||||.|||| .|.
leaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketv

DHFWEMVWETKASTIVMMTALVEGGKTKCEHYWPTGQKphLHGNVTVTLVGSKQTEHFIQRTLLIG--KKGTELTVTHYQYLAWTDHGVPASTAPLVAL-
| ||.|..| |.  |||.| | || . || .||  |..   .|.| | |   ...  .| | | .   |.    .||..|| .|.....|.    |. | 
ddfwrmiferkvkvivmltelkeGdrekcaeyweeGkr--ayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkli

------LYQVKMTSQEDGALTGPIIVHCSAGIGRTGTFIAADMLMNAIQrstATDYIDIAGTVAKLREQRTSLVQTL
      | | . .   .   ..|..|||..| .|||.||| . |.....   | . .|. . | ||| .|. .|.. 
qvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesle---aeekvdvfqvvkklrkarplmvsve
Phosphatase Spur_PTPRB7.AA Subfamily.N14.PD 12-255 37 1.6e-58 189.6 In-house 5-261 (275) Show / Hide 
Range on Protein: 12-255
Range on HMM: 5-261/275
Sequence Identity: 37% (95 aa)

EYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQLKG--EVGNDYINASYIADDQG--NRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTAL
||. .| ...   ...|..  | .||||...|||. |||.|.   |  ..||||| |    |  .|.||..||||..|.  ||.||||.. .|||.|.  
eyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmltee

VEGGKTKCEHYWPTGQKP---HLHGNVTVTLVGSKQTEHFIQRTLLIGK--KGTELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEDG-------
|.||.|. .|.|  ..      .|.  ||   |.... .| ..| .     . | || | ||  |.|||||    ...  | .|...             
eedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvk

ALTGPIIVHCSAGIGRTGTFIAADMLMNAIQRStatDYIDIAGTVAKLREQRTSLVQTLV
|..||||||.||||  | .|.|.....     . |||  ..|.||.|| .|||||     
eskPPvlvhCsaGvGrtGvlilsdlliatlehn---eeidikkvlarLrkqrmllvqtla
Phosphatase Spur_PTPRB7.AA Subfamily.N23.PD 45-254 38 4.8e-55 178.5 In-house 114-335 (350) Show / Hide 
Range on Protein: 45-254
Range on HMM: 114-335/350
Sequence Identity: 38% (85 aa)

YDYNRVQLK----GEVGNDYINASYIADDQ-GNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWPTGQ-KPHLHGNVTVTLVGS
| |||.|.     .  .|||||.|. .   .  ..||||||...|.  || |||| ..|.|||.|  |||.|.||..|||. . ...|.|...|.|   .
hdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslksl

KQTEHFIQRTLLIGKKGTE--LTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTS------QEDGALTGPIIVHCSAGIGRTGTFIaadMLMNAIQRSTA
..|..|.|.| . .. ..   .|.| .. .|...|||.|   |.|.| .|. .       . .|.   |||.|||||.||||||... ||.  ||    |
rssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfc---vvysairelta

T-DYIDIAGTVAKLREQRTSLVQTL
.|   | .||.||   ||.      
gngiiniprvvrrlrqqRkymvqkk
Phosphatase Spur_PTPRB7.AA Subfamily.RN.PD 13-253 38 5.2e-55 178.0 In-house 6-248 (264) Show / Hide 
Range on Protein: 13-253
Range on HMM: 6-248/264
Sequence Identity: 38% (95 aa)

YNSLPAMEKI-RAVTVARNARNDDKNRFRNILPYDYNRVQLKGEV---GNDYINASYIADD-QGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTAL
...| | |   .. .||.. .| .||| ...|||| .||.|| |     .|||||| | |.   .  ||||||||..|| .||.||||  .  ||..| |
wealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrl

VEGGKTKCEHYWPTGQkPHLHGNVTVTLVGSK-QTEHFIQRTLLIGKKGTE--LTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQedGaLTGPIIVH
 | | ..|..|||     ....   | ||  .  .. .. |.. .    |.   ||| . .|.|...|||||. .|. .  .|  . .|  . ||.||||
eeegvkqckrywpdeG-sevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyr--G-rscpivvh

CSAGIGRTGTFIAADMLMNAIQRSTatDYIDIAGTVAKLREQRTSLVQT
.| ||||..|. |.... ...      |||| |. .||.||. ||.|  
csdGaGrtGvyilidlvlerllkGv--keidiaatlehlrdqrpglvkt
Phosphatase Spur_PTPRB7.AA Subfamily.N20.PD 30-253 43 1.1e-53 174.0 In-house 23-241 (257) Show / Hide 
Range on Protein: 30-253
Range on HMM: 23-241/257
Sequence Identity: 43% (98 aa)

NARNDDKNRFRNILPYDYNRVQLKGevGNDYINASYIADDQ--GNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWPTGQK-PH
.  | .|||.|.|||||  || |     .||||||||   .   .  |||||||| .||| ||.|| | ..  | |.|  .|||  || ||||| |    
qpsnreknryrdilpydstrvplgk--skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkpl

LHGNVTVTLVGSKQTEHFIQRTLLIGKK--GTELTVTHYQYLAWTDHGVPASTAPLVALLYQVKmtsqeDGALTGPIIVHCSAGIGRTGTFIAADMLMNA
 . | |   .  ..|| | . . .|  ||  .| . |.  | ||| |||.  ..  .   .        ||||..||||||||||| |.. |... || .
elkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryar-----kshltgpmvvhcsagigrtgvflcvdvvfca

IQRSTATDYIDIagtVAKLREQRTSLVQT
  . . .||   ||..||||. .|||   
ivkncsfnimdi---vaqmreqrsgmvqt
Phosphatase Spur_PTPRB7.AA Subfamily.N_Nematode_1.PD 10-253 35 1.9e-52 169.7 In-house 3-249 (265) Show / Hide 
Range on Protein: 10-253
Range on HMM: 3-249/265
Sequence Identity: 35% (89 aa)

SDEYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQL-KGEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALV
||...|  ...   |.. ..|...||||....   | |||.| .. . .||| | |..     ...| .|.|| .||..|| ||   |  .|||.  |.|
rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckli

EGGKTKCEHYWPTGQKPHL--HGN---VTV-TLVGSK---QTEHFIQRTLLIGKK-G-TELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTsqedgal
 ||.||..|.|. ....|  . .   .|| . .|.|   ..|..|. | |  .  | ....|||||.| |.|||.     . || .|..        .||
ekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs-------

TGPIIVHCSAGIGRTGTFIAADMLMNAIQRSTATDyiDIAGTVAKLREQRTSLVQT
|.|||||||||||| .| ..... .  ..  .  |.   | |.||||..||     
kgPivvhCsaGiGrtGtivaieyildkllegkqie--dmeklvkkireqrnysiqt
Phosphatase Spur_PTPRB7.AA Subfamily.R_Nematode_2.PD 25-253 34 7e-49 157.9 In-house 21-245 (261) Show / Hide 
Range on Protein: 25-253
Range on HMM: 21-245/261
Sequence Identity: 34% (80 aa)

VTVARNARNDDKNRFRNILPYDYNRVQLKGEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWPTGQK
||   .  ..||.|. ..   .  .|. . .     | | ... .. ....||||||| || . || ||   |  .|||..  ||  |.|||.|.|. ..
vtesaaylpkdkhRypdvPCkpetavevivdgkrvpihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfplets

PHLH-GNVTVTLVGSKQ--TEHFIQRTLLIGKKGT---ELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQedgaltgPIIVHCSAGIGRTGTFIAA
 .|. |..... |. ..  ...  .||| . ..       |||||||  |.|.||| | | |  ||||   .       ||.||||||||||..||....
qkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek-------PivvhCsaGiGRtmafigt

DMLMNAIQRstaTDYIDIAGTVAKLREQRTSLVQT
| ....     . | .. ....|||.|.  .||  
eylarevea---dptieltealkelrehRwkgiqt
Phosphatase Spur_PTPRB7.AA Subfamily.N_Nematode_4.PD 24-253 35 6.3e-48 154.9 In-house 17-248 (264) Show / Hide 
Range on Protein: 24-253
Range on HMM: 17-248/264
Sequence Identity: 35% (84 aa)

AVTVARNARNDDKNRFRNILPYDYNRVQLKGE-VGNDYINASYIADDqGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWPTG
.||.    .| ||||...||  | .|| ||     |||| ||..     . .||.|||||..|.. || ||.. |....||.|.|.|  ||. |.|  ..
nvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypek

QKP-HLHGNVTVTLVGSKQT--EHFIQRTLLIGKKG-------TELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQEdgaltGPIIVHCSAGIGRT
  . .|.  .|||  |.      | ..| . .          .| | |.|.  | |.  |  .||.. |.  ||  ..|     .||.||||||.||| |
sekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkke-----kPivvhcsaGvGrt

GTFIAADMLMNAIQRSTATDYIDIagtVAKLREQRTSLVQT
..  |.    |.  .  . .||   | .||. |   ||.  
atlvGidyatirirenseievldi---vrelramrlkavqs
Phosphatase Spur_PTPRB7.AA Subfamily.N_Nematode_6.PD 10-255 34 2.9e-47 152.8 In-house 3-239 (253) Show / Hide 
Range on Protein: 10-255
Range on HMM: 3-239/253
Sequence Identity: 34% (84 aa)

SDEYNSLPAMEKIRAVTVArnARNDDKNRFRNILPYDYNRVQLKGEvGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVE
||.. | .  .. .|.    ...|.||..||  .|  |..|...  . || |...   . .|..| ||.|| .||..||.|..    |||.  ||| || 
kkeykdspneaseseataf--lkfkdrnrytniqCcdagrlkladd-edfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelve

GGKTKCEHYWPT--GQKPHLHGNVTVTLVGSKQTEHFIQRTLL-IGKKGT-ELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQedgaltgPIIVHC
|. .| .   |.. ..    ||. .| |. .  ..|.|. | |.|  |  | |... .| ||||| |    . ||  || . .       ||.||||||.
kgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk-------PivvhC

SAGIGRTGTFIAADMLMNAIQRstaTDYIDIAGTVAKLREQRTSLVQTLV
|||||..   ....|..    .|....   ..||||.|   ||| |    
saGvGrtGtlaliliilealrl---pdfqgvkdllvklreerfravqtev
Phosphatase Spur_PTPRB7.AA Subfamily.R_Nematode_3.PD 32-253 27 2.6e-39 126.7 In-house 22-251 (267) Show / Hide 
Range on Protein: 32-253
Range on HMM: 22-251/267
Sequence Identity: 27% (66 aa)

RNDDKNRFRNILPYDYNRVQLKG---EVGNDYINASYIADDQGNrKYIATQGPL--------PNTIDHFWEMVWETKASTIVMMTALVE---GGKTKCEH
.. ...|  ... .  .|| |||      .|.|.|...   .|. | | ||.|.         .||. || |. ..|.  .||.||   ... || .|.|
kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpngl-klIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcse

YWPTGQKPHLH-GNVTVTL--VGSKQTEHFIQRTLLIG-KKGTELTVTHYQYLAWTDHGVPASTAPLVALLYQVKMTSQedgaltgPIIVHCSAGIGRTG
. .. .|. ..|.|.   . ..  | . .||| .  .|. | ||||..| .|.....| .. ....|.  |.   .       |..||||.||.|..|. 
YypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfvekskt-------pvvVHCsdGisRsa

TFIAADMLMNAIQRSTAtdYIDIAGTVAKLREQRTSLVQT
|... .. | .|.    .|..  . .||.||   .||   
tlaaielgyqliikskg--kldllslikelrkqRagaiqt
Phosphatase Spur_PTPRB7.AA Subfamily.N_Nematode_5.PD 24-254 25 4.8e-37 119.1 In-house 16-243 (258) Show / Hide 
Range on Protein: 24-254
Range on HMM: 16-243/258
Sequence Identity: 25% (58 aa)

AVTVARNARNDDKNRFRNILPYDYNRVQLKGEVgNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWPTGQ
.|     .| .|||  ..  .| .||.|. |  ..|||||.|  |. ..|.| || |||.|.  ||.|| ..|  ..|...|  .|... .  . ..   
ketckafeknlkknrskdvkilDetrVkltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletg

KPHLHGNVTVT--LVGSKQTE--HFIQRTLLIGKKGTeLTVTHYQYLAWTDHGVPASTAPLVAllYQVKMTSQEDGALTGPIIVHCSAGIGRTGTFIAAD
.|.....   | .|..|  ..   .|  |.    . ...|..  |... ||........   ...  .... .   |..|....|.||.|||..... ..
dylnlgkmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagtfllls

MLMNAIQRSTATDyidIAGTVAKLREQRTSLVQTL
 ...  . .   |. .. |.|.||   |..|    
vaieqlnngkepn---ideilkkirsqRpgavesl
Phosphatase Spur_PTPRB7.AA Subfamily.N_Nematode_egg.PD 9-253 23 5.7e-29 92.8 In-house 2-241 (257) Show / Hide 
Range on Protein: 9-253
Range on HMM: 2-241/257
Sequence Identity: 23% (58 aa)

FSDEYNSLPAMEKIRAVTVARNARNDDKNRFRNILPYDYNRVQL---KGEVGNDYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMT
.  ... |  . .  ..| | .. . .| | . .   .. ||.|   .|   .|.| | ..  .    ..| .| || || .|| ||.. |   |||.|.
lerrfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmlt

ALVEGgkTKCEHYWPTGQKPHLH---GNVTVTLVGSKQTEH--F-IQRTLLIGKKGTELTVTHYQYlAWTDHGvpASTAPLVaLLYQVKMTSQedgaltg
 .|    .||.|||  ..  |    |.. .. .. ..     | . .  |.| .  || . |.|.  .   .      ||  .| ...  |.       |
sakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg-dvnyls--dvysplr-vlrklrnlsk-------

PIIVHCSAGIGRTGTFIAADMLMNAIQRSTATDYIdIAGTVAKLREQRTSLVQT
..|..  |. ...|..|... .  . |   | .. .  .|  ||.|   |..  
pvvvqdilGvskaatlvaieiallsllrGpitksl-vlravvflrlrrrlsves
Phosphatase Spur_PTPRB7.AA Subfamily.N_Fungi_PTP1.PD 34-127 40 1.8e-27 87.8 In-house 46-156 (343) Show / Hide 
Range on Protein: 34-127
Range on HMM: 46-156/343
Sequence Identity: 40% (41 aa)

DDKNRFRNILPYDYNRVQLK-----------GEVGNDYINASYIADD------QGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCE
|||..|||||. .||.||              .||||||.|.         . . ||||||.|||.|.| |.... . ||...|..|| .  ||..||. 
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy

HYWPTGQKPHL
|.         
rYWqegsyddi
Phosphatase Spur_PTPRB7.AA PTPc_motif 159-257 35 3.9e-27 97.38 SMART 1-92 (92) Show / Hide 
Range on Protein: 159-257
Range on HMM: 1-92/92
Sequence Identity: 35% (40 aa)

TVTHYQYLAWTDH-----GVPASTAPLVALLYQVKMTSQEDGALTGPIIVHCSAGIGRTGTFIAADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQT
||.||.|..| ||     |||    ... ....|.           ||.||||||.||||||.|.||.|.          .|| .|| ..|.||  .|||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK----------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQRPGMVQT

L---------VRD
.         . .
EEQYIFCYRCILE
Phosphatase Spur_PTPRB7.AA Subfamily.N_Nematode_eak.PD 20-177 28 1.2e-22 72.1 In-house 13-173 (281) Show / Hide 
Range on Protein: 20-177
Range on HMM: 13-173/281
Sequence Identity: 28% (45 aa)

EKIRAVTVARNARNDDKNRFRNILPYDYNRVQLKGEVGN--DYINASYIADDQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEH
.......|..   . ..||  .|.|.|.. |.|     |   ||||| .   .  |||| |  .  . .  ||.|| | |..||..   || .  | . |
qrllsirvtarleavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdk

YWPTGQKPHLHGNVTVTLVGS-KQTEHFIQRTLLIgKKGTE-LTVTHYQYLAWTDHGVPAST
.|   .   .| . |.      . . .  | | . .|| |   | ||..  ||.  .|    
yfpdktevlkyGildverkeyavkrniletrllil-rkGnethrvlhykvfGwtettlpkye
Phosphatase Spur_PTPRB7.AA Subfamily.N_Fungi_PTP1.PD 157-254 32 4.3e-15 47.0 In-house 212-328 (343) Show / Hide 
Range on Protein: 157-254
Range on HMM: 212-328/343
Sequence Identity: 32% (37 aa)

ELTVTHYQYLAWTDHGV---PASTAPLVA----LLYQVKMTSQEDGALTGPIIVHCSAGIGRTGTFIAADMLMN-------AIQRSTATDYID-----IA
.| . |.  | | ..   | |  . .     |. .    |  | | . ||.||||||.|||||... |.|..         ..|.  |.       |  .
pyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlis

GTVAKLREQRTSLVQTL
| .||.|| |.||.|  
iivnelrkqrismvqnl
Phosphatase Spur_PTPRB7.AA Family.DSP.PD 95-235 16 1.6e-11 35.7 In-house 130-223 (387) Show / Hide 
Range on Protein: 95-235
Range on HMM: 130-223/387
Sequence Identity: 16% (24 aa)

ETKASTIVMMTalveggktkcehywptgqkphlhgnvtvtlV------GskqtehfiqrtlligkkgtELTVTHYQYlAWTDHGVPASTApLvaLLYQVK
| . . || .|                                                         || ...... .. ||..|     |  ... ..
elgvtkivnlt------------------------------ddkpqftk-------------------elgikylri-pidDhnapplen-l--fekaid

MTSQEDgALTGPIIVHCSAGIGRTGTFIAADMLMN-AIQRSTATDYID
. .   .| . ||| ||.||.|| |.| .. .  .  . | |...   
fieegn-dskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvr
Phosphatase Spur_PTPRB7.AA Subfamily.PTPDC1.PD 160-253 30 1.3e-10 32.6 In-house 135-213 (229) Show / Hide 
Range on Protein: 160-253
Range on HMM: 135-213/229
Sequence Identity: 30% (28 aa)

VTHYQYlAWTDHGVPAstapLVALLYQVKMTSQEDgaLTGPIIVHCSAGIGRTGTFIAADMLMNaiQRSTATDyidiagTVAKLREQRTSLVQT
...|.. ...|.||..    |  .|  ||. ..    . | | ||| || ||||  ||. .. .  .| || .       . ..|..|..||  
iyfynf-glkDygvas----leriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylvya--krltaee------aiklvrskrpksiqt
Phosphatase Spur_PTPRB7.AA Subfamily.CDC14.PD 197-233 45 7.4e-09 27.1 In-house 197-231 (258) Show / Hide 
Range on Protein: 197-233
Range on HMM: 197-231/258
Sequence Identity: 45% (16 aa)

LTGPIIVHCSAGIGRTGTFIAADMLMNaiQRSTATDY
.| |.||| ||.|||||.|.. .. .  .| ||..  
aeGaiavhCkaGLGrtgtligcylikh--yrftaaet
Phosphatase Spur_PTPRB7.AA Subfamily.DSP23.PD 181-253 28 9.9e-08 23.7 In-house 52-113 (128) Show / Hide 
Range on Protein: 181-253
Range on HMM: 52-113/128
Sequence Identity: 28% (21 aa)

VALLYQVKMtsqEDGALTGPIIVHCSAGIGRTGTFIAADMLmnAIQRSTATDYIdiagtvAKLREQRTSLVQT
|| |...     |  .  ... |||  |.|||||..|  ..  . .. .| | |      | .|..|   ..|
varlvrive---eaekkeeavgvhcalGlGrtGtllacylv--keeglaaddai------aevrkrrkGsiet
Phosphatase Spur_PTPRB7.AA Subfamily.PTEN.PD 201-229 48 2.3e-07 21.9 In-house 97-125 (305) Show / Hide 
Range on Protein: 201-229
Range on HMM: 97-125/305
Sequence Identity: 48% (14 aa)

IIVHCSAGIGRTGTFIAADMLMNAIQRST
..||| || ||||. |.| .|.. |..|.
vavHCkaGkGRtGvmicayLlksgikksa
Phosphatase Spur_PTPRB7.AA Subfamily.PTPMT1.PD 160-252 20 5.6e-06 17.8 In-house 53-141 (146) Show / Hide 
Range on Protein: 160-252
Range on HMM: 53-141/146
Sequence Identity: 20% (19 aa)

VTHYQyLAWTDHGVPASTAPLVallYQVKMTSQEdGALTGPIIVHCSAGIGRTGTFIAADML-MNAIQRSTATDYIDIAGTVAKLREQRTSLVQ
|...| || .|..  .|.. |      |.. ...   .   . ||| || .| .| .|. .. .. ..   |....       .|..... .| 
veqlq-latvDfteapslekle---egvefiekv-askgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralq
Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPRB7.AA Protein None 258 None Fasta, JSON
Spur_PTPRB7.NA RNA None 774 None Fasta, JSON
Spur_PTPRB7.AA.PD_8-257 Protein Phosphatase Domain None 250 None Fasta, JSON