Gene Spur_PTPRB8
Spur_PTPRB8
Species: S.purpuratus
Alias: Spur_PTPRB8, hmm7097, Spur_hmm278640
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Spur_PTPRB8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Fn3 | Spur_PTPRB8.AA | FN3 | 710-787 | 22 | 2.1e-14 | 55.08 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 710-787 Range on HMM: 1-69/69 Sequence Identity: 22% (21 aa) PTPPQN---VTVTNVTEQ------SITIAWTPGAGYRTRYHLHAYATSYSEEVGVVHGDVTDFTFHNLLAG----TRYIITIRASAN--DTDG | ||.| ..||.||. |.|. |.| ...|. .|...| .| |.| ...|| . | PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | Spur_PTPRB8.AA | FN3 | 801-887 | 19 | 6.1e-09 | 36.94 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 801-887 Range on HMM: 1-69/69 Sequence Identity: 19% (20 aa) PGPVDR---LRLEPQIDHR-----QIRLAFLAPMLPNGVLEGYRVEYVGKRNGSRTCSSGQKYLPVVETSVIIEGLKGG----CYYTFTVKARNE--VGL |||. . ||... ... ...| .| .|.|. ....||| | |.|.|.|.|. .| PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE G | G |
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| Phosphatase | Spur_PTPRB8.AA | PTPc | 1066-1263 | 27 | 5.8e-55 | 189.83 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 1066-1263
Range on HMM: 1-308/308
Sequence Identity: 27% (86 aa)
KDVELTRAIRKVGRKM---------TTNTAVSPANV--GKNRYT-NILPYDRTRVKLSPVDDE----EGSDYINSNYIPGFTSPREYIACQGPLPGTTDD
. | ..... .. ....| .|.|. ||||. .|..||.|||||.| ..| ||||||| |||.|. .|..||..|||||.| .|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED
MWRMIWEQNVTTVVMVTQLVEK--------GKVKCDQYWPDDHMPVLYGDIQVTMNQTFEEN-DWNIKEFAVQLRD----------QRRYVRHWNFLSWP
|||.|.|.....|| ....|| |..||.|||||. |. ||.|.||. . . |.....| |. . . | |.|... .||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP
DHGVPESSQALLAFIRRIRSTKPPS-------------------SAPVAVH-------------------------------------------------
|||||||....|.|||..|.... | ..|. ||
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIENVDIFQIVKMMRNQRPGMVQTEEQYIF
---------C
CYRCILEYIK
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.RB.PD | 1070-1263 | 53 | 8.5e-87 | 281.7 | In-house | 5-200 (261) | Show / Hide |
Range on Protein: 1070-1263 Range on HMM: 5-200/261 Sequence Identity: 53% (104 aa) LTRAIRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLV .. ..|||.......| ...| |||.||||||| .||||. ..||...||||.|||||..|||||||.|||||.|.||.|||.||......||.||||| eyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlv EKGKVKCDQYWPDDHMPVLYGDIQVTMNQTFEENDWNIKEFAVQLRDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRST--KPPSSAPVAVHC |||.||..|||.|. |||||||.||.... |...| |.||... ....| ||...|.|||||||||....||.|.|..|..| .|..|. ||| EkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHC |
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| Phosphatase | Spur_PTPRB8.AA | Y_phosphatase | 1091-1263 | 44 | 4.4e-84 | 290.46 | Pfam | 1-185 (243) | Show / Hide |
Range on Protein: 1091-1263 Range on HMM: 1-185/243 Sequence Identity: 44% (83 aa) NVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPG-FTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGK-VK-CDQYWPD--DHM | ||||..|..||.|||||.|....|.||||| |||.| ...|..||..|||.| | .| |||.|.|..|..||.....|.|. .| |.||||| .. NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ PVLYGDIQVTMNQTFEENDWNIKEFAVQLRD----QRRYVRHWNFLSWPDHGVPES-SQALLAFIRRIRSTKP-PSSA--PVAVHC |. |||.|||. . ...|... .| |. . ..| |.|. ...||||||||| ....| |||..|. .| | . |. ||| PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.R_Anemone_2.PD | 1072-1263 | 43 | 4.6e-69 | 223.8 | In-house | 8-201 (262) | Show / Hide |
Range on Protein: 1072-1263 Range on HMM: 8-201/262 Sequence Identity: 43% (85 aa) RAIRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEK | |. .|...|..|.| ||||.|||.||.|||||.....||||||||.|||.|... ..|||.|.||| | .|.|||.|||| ...||.||..|. rlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeer GKVKCDQYWPDDHmPVLYGDIQVTMNQTFEENDWNIKEFAVQLR--DQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTK-PPSSAPVAVHC ||.|...|||.. . ||...|......| .|. ...| |. .. | || ... ||||.|||||. ||...|...... ... |..||| gkakvhryWPskg-srsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Choan_1.PD | 1073-1263 | 38 | 1.3e-64 | 209.1 | In-house | 8-200 (262) | Show / Hide |
Range on Protein: 1073-1263 Range on HMM: 8-200/262 Sequence Identity: 38% (74 aa) AIRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKG .....|.. |.. . ...|| ||||.|| || ||||..| .... .||||.|..||.....||||.|||.| . ...|.|.|||.|...||||. .|.| klaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieag KVKCDQYWPDDHMPVLYGDIQVTMNQTFEENDWNIKEFAV-QLRDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRI-RSTKPPSSAPVAVHC |.|| .||||.. . .||..|..... |.. . ..| . . . | |.. ....|||||||.....|| | . . . ||. . ||. .|| klkChryWPdenselklgdvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.R_Sponge_2.PD | 1079-1263 | 37 | 7.2e-62 | 200.1 | In-house | 13-201 (262) | Show / Hide |
Range on Protein: 1079-1263 Range on HMM: 13-201/262 Sequence Identity: 37% (71 aa) RKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPvDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQ ......| .. ||||||...||||| .||.|.. |....||||| ... |. .. ||| ||||. | .|.|||.||..|.|.||.|.|.|.|| || .| tefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcak YWPDD-HMPVLYGDIQVTMNQTFEENDWNIKEFAVQL---RDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPPSSA-PVAVHC ||. . | ||...||.... . .|. |... .. ..... |....|..||.|.||... .||..|.|.. .. | .. |.| YWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N12.PD | 1073-1263 | 44 | 1.9e-60 | 195.2 | In-house | 14-206 (270) | Show / Hide |
Range on Protein: 1073-1263 Range on HMM: 14-206/270 Sequence Identity: 44% (85 aa) AIRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKG . | ....|... .. || |||| .||||| .||.|| ..||||||||.|.| | ... ||||.||||| | || ||||||.||. |||. ..|| | ekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelg KVKCDQYWPDD-HMPVLYGDIQVTMNQ-TFEENDWNIKEFAVQLRDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPPSSAPVAVHC | ||..|||. .... .|...||... ..|. |. ..|. ....| |. ... .|||||||.| . ||..|. .|.....||..||| kkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N9.PD | 1073-1253 | 40 | 4.2e-60 | 194.5 | In-house | 8-191 (275) | Show / Hide |
Range on Protein: 1073-1253 Range on HMM: 8-191/275 Sequence Identity: 40% (75 aa) AIRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKG .||. . | ... ..||. |||||..| ||.|||||. .|..| |||||.|.. |. .. .|| ||||. |..| |||.|||.| ..||.|..||.| dirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvverg KVKCDQYWP-DDHMPVLYGDIQVTMNQTFEENDWNIKEFAVQ--LRDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKP ..|| |||| ... .||..|. .. .|.|.... . .. .. | | |. ||||||.|||.|...|| .....|... rlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqa |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N3.PD | 1079-1263 | 41 | 3.1e-58 | 188.0 | In-house | 14-200 (261) | Show / Hide |
Range on Protein: 1079-1263 Range on HMM: 14-200/261 Sequence Identity: 41% (78 aa) RKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSpvdDEEGsDYINSNY----IPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKV .....| |.|. |||| .||||| |||||. ..| ||||.|| ||... |||.||||. |. |.|.|.|||..|..||.|.|||.|.||| pglaisaarkpenlaknryrdilpydatrvklk---eset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrv KCDQYWPDDHMPVLYGDIQVTMNQTFEENDWNIKEFAVQLRD--QRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPPSSAPVAVHC ||||. . . .|...|..... |.. . ..|. .. .. ..| . . .|.|||||||..|. .| |..|.|... ..|| ||| kChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.RG.PD | 1077-1263 | 35 | 5.1e-58 | 187.5 | In-house | 13-203 (264) | Show / Hide |
Range on Protein: 1077-1263 Range on HMM: 13-203/264 Sequence Identity: 35% (67 aa) VGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKC . ........ .. | |||..||....|.||||||. ...|.|||| .|| |. .|||. ||||. |..| ||||||.|....||.|.|.|||. .. kpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrde DQYWPDDHMPVLYGDIQVTMNQTFEENDWNIKEFAVQLR----DQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPPSSAPVAVHC |.|||... |. .....||. .. . .. ...| .. . ...| ||.... .|||.|.|||. | |... ... ..|. ||. dvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhd |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.RK.PD | 1079-1263 | 37 | 7.3e-58 | 186.7 | In-house | 17-206 (267) | Show / Hide |
Range on Protein: 1079-1263 Range on HMM: 17-206/267 Sequence Identity: 37% (72 aa) RKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEeGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQL-VEKGKVKCD . ..|. . | |||...||.|||..|.| .||.. |||||...| ... |...|. ||||. |. |.||.....| ...||.|.| ||.|.||| qsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkCl QYWPDDHMpVLYGDIQVTMNQTFEENDWNIKEFAVQL----RDQRRYVRHWNFLSWPDH-GVPESSQALLAFIRRIRSTKPP-SSAPVAVHC .|||.| . | ||||.|.. .. ..| .. |.|. ...| ||...||.||.. .||.| ..||..|||. ..... ... ||| kyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.R_Anemone_1.PD | 1078-1263 | 34 | 3.5e-57 | 184.9 | In-house | 12-197 (258) | Show / Hide |
Range on Protein: 1078-1263 Range on HMM: 12-197/258 Sequence Identity: 34% (65 aa) GRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCD ........| ..| ||||..|...| .|| |. ....| |||||. |. .. |..||.|.||. |..| |||.|.......||.|.|.|. | || ikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkch QYWPDdhMPVLYGDIQVTMNQTFEENDWNIKEFAVQLRDQR--RYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPPSSAPVAVHC ||||| . ||...|..... . |. |...... .... |.|....|..|||.|||. ..|.|.. |...... . ..|| ||| qYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.RA.PD | 1080-1263 | 40 | 1.6e-56 | 182.5 | In-house | 16-205 (266) | Show / Hide |
Range on Protein: 1080-1263 Range on HMM: 16-205/266 Sequence Identity: 40% (76 aa) KMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQY | . .|| ..| |||. .||||| .|| || .. || |||||. .| |. ..||.|||. | .|.|||||||. .|.||.|.| |... || || keklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqy WPDDHMpVLYGDIQVTMNQTFEENDWNIKEFAVQ------LRDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPPSSA-PVAVHC |||. . | ||.|.|..... . .|. ...| |. ... | || . | |||. ||| ... .| .......... |..|..||| wpdeGl-vtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N13.PD | 1074-1263 | 39 | 9e-54 | 173.6 | In-house | 9-198 (259) | Show / Hide |
Range on Protein: 1074-1263 Range on HMM: 9-198/259 Sequence Identity: 39% (77 aa) IRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSpvdDEEGsdYINSNYIPGF--TSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEK .|.. . |.... . .| |||| |.||||.|||||. || | |||...| |||||||||| |..|.|.|.|||... ..|||. .|| lrelkpldtcevgkkkenkdknryrnvlPydetrvklg---degg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekek GKVKCDQYWPDDHM-PV-LYGDIQVTMNQTFEENDWNIKEFAVQLRD--QRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPpSSAPVAVHC |||||..|||. . .. ... ..|.. .. . ........||. . . | | | || .||||||| |.. |. |....|. . ...|..||| gkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.R_Ecdysozoa.PD | 1077-1263 | 34 | 4.1e-53 | 171.2 | In-house | 13-208 (269) | Show / Hide |
Range on Protein: 1077-1263 Range on HMM: 13-208/269 Sequence Identity: 34% (69 aa) VGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVkC . . .|... | |||| .| ..|.|||||... .| |||||...| |. ...|| |.|. .| .|.||||.||.||..||...| || . | leiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-c DQYWPDDhMPVLYGDIQVTMNQTFEENDWNIKEFAVQLRD-----QRRYVRHWNFLSWP-DHGVPESSQALLAFIRRIRSTKPPS-----SAPVAVHC ..|||.. | |||| |.. .. . .|. |.|. | . ..| | ... .|. | |||....|| .|...|. . . .|. ||| akyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N6.PD | 1079-1263 | 35 | 6e-51 | 164.4 | In-house | 28-231 (295) | Show / Hide |
Range on Protein: 1079-1263 Range on HMM: 28-231/295 Sequence Identity: 35% (73 aa) RKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPV-DDEEGSDYINSNYI----------PGFTSP---REYIACQGPLPGTTDDMWRMIWEQNVTTVVM .... . . . | |||| ||||.| |||.|. . .. ||||||.||| . | ..||| ||.|. | | |||.|..| . .|| klysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivm VTQLVEKGKVKCDQYWPDDHMPVLYGDIQVTMNQTFEENDWNIKEFAVQLR---DQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTK--PPSSAPV .|. ||.|| || .|||| . .|.|.||. . ...|....|| |. . .. |......| .|||||||......| |.. ..... .. |. ttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpi AVHC ||| vvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N5_RR.PD | 1088-1263 | 36 | 4.2e-50 | 161.5 | In-house | 20-204 (265) | Show / Hide |
Range on Protein: 1088-1263 Range on HMM: 20-204/265 Sequence Identity: 36% (65 aa) SPANVGKNRYTNILPYDRTRVKLS-PVDDEEGSDYINSNYIPGFTS-PREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQYWPDDH- . . ||||..||| ...|| |. ..| |.|||.||| |. . |.| ||||| | .|.||||....|. .||.|.| |. .|| .|.||.. vfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaed --MPVLYGDIQVTMNQTFEENDWNIKEFAVQLRDQ-RRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTK---PPSSAPVAVHC . |||........ |.||...... .. . .| | |. . .|||| .|.. ..|| ... .....||| ||| yeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Choan_2.PD | 1086-1263 | 35 | 1.4e-49 | 159.6 | In-house | 14-205 (266) | Show / Hide |
Range on Protein: 1086-1263 Range on HMM: 14-205/266 Sequence Identity: 35% (67 aa) AVSPANVG--KNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFT-SPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQYWPD |. .. . |||..||| .|||.|....... . ||| ||..||. ....||| .|||| |. . ||||||..||..||.|.|.|||. ||..||| aiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa ---DHMPVLYGDIQVTMNQTFEENDWNIKEFAVQLRDQRRYVRHWNFLSWPDHGVPESSQ------ALLAFIRRIRSTKP-PSS-APVAVHC ... . .|.|.|. .. |. . ... .. ... | ..|. . .|||||||.... ||..| .| .. . |. ||| epkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.RC.PD | 1074-1253 | 34 | 4e-44 | 141.9 | In-house | 9-207 (288) | Show / Hide |
Range on Protein: 1074-1253 Range on HMM: 9-207/288 Sequence Identity: 34% (68 aa) IRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKL-------------------SPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMI . .| |.| . | . | ||||...|||| ||.| . .| ||||.|||. .| .. |. ||| |||| |||.||||. lpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmi WEQNVTTVVMVTQLVEKGKVKCDQYWpdDHMPVLYGDIQVTMNQTFEENDWNIKEFAVQL--RDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTK |. |. .||.|.| | . || .|| . |||..| ...| .|. .. . .. | . | | .... ||.....||. || .|. .. | ferkvkvivmltelkeGdrekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqkl P p |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N14.PD | 1074-1252 | 33 | 8e-42 | 134.3 | In-house | 9-193 (275) | Show / Hide |
Range on Protein: 1074-1252 Range on HMM: 9-193/275 Sequence Identity: 33% (63 aa) IRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEeGSDYINSNYIPG--FTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEK | | . ...|| | |. |||. ..|||. .||.||| .. ..|||. | .. |.||..||||. | |.|.|.|||.|. .||.|. |. ipkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeed GKVKCDQYWPDD---HMPVLYGDIQVTMNQTFEENDWNIKEFAVQ--LRDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTK || |. .|.|.. . | .| .|| . . . . . . .. . ..| | | . |||||||| . .| |.....| . gkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvr |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N1.PD | 1080-1263 | 35 | 2.2e-40 | 129.8 | In-house | 17-204 (268) | Show / Hide |
Range on Protein: 1080-1263 Range on HMM: 17-204/268 Sequence Identity: 35% (68 aa) KMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDeegsDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQY .. |..| |.| |.||| .. ||| .|.|| | ||||.. . |.|| ||||| |.| |.|.|||| .|.|. ..|||...|| || eletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy WPDDHMP--VLYGDIQVTMNQTFEENDWNIKEFAVQLRD----QRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKP--PSSAPVAVHC || .. .|. ... ... ||. . ..|.| . | . |. . ||| ||||| .|.| |. ..|.. ...|. .|| wpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.RN.PD | 1081-1263 | 40 | 8.9e-39 | 124.2 | In-house | 17-202 (264) | Show / Hide |
Range on Protein: 1081-1263 Range on HMM: 17-202/264 Sequence Identity: 40% (75 aa) MTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGfTSPRE--YIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQ |...| .. || |||....|||| .||||. .| |||||. | . ||. |||.||||. | |.|.|.||| |. .|..|.| |.| .|..| stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaild-hdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckr YWPDDHMPVlYGDIQVTM-NQTFEENDWNIKEFAVQ-LR-DQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKPPSSAPVAVHC |||. | |. .| . . .|. .. | .. |. .. | | . |||||..||| |...|| | |.. . |.|.||| ywpdeGsev-yhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N23.PD | 1091-1252 | 35 | 7.5e-38 | 121.4 | In-house | 102-268 (350) | Show / Hide |
Range on Protein: 1091-1252 Range on HMM: 102-268/350 Sequence Identity: 35% (58 aa) NVGKNRYTNILPYDRTRVKLS-PVDDEEGSDYINSNYIPGFTSP-REYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQYWPDDH-MPV |... |. |..|||| . .. .||||. |. |. ..|| |||.. | | | |.||| . ..||.|. ||..| ||||||| |. ..|. gsGqqqgtpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetn LYGDIQVTMNQTFEENDWNIKEFAVQLRDQR--RYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTK ||..|..... . . | . . .| .|.. | | | .. .|...|||.| . ||||. .... lfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetay |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Nematode_1.PD | 1072-1263 | 31 | 2.4e-36 | 116.3 | In-house | 7-203 (265) | Show / Hide |
Range on Protein: 1072-1263 Range on HMM: 7-203/265 Sequence Identity: 31% (63 aa) RAIRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSpvDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEK ||..| .. .... . . .||||... |..||||. .. |||| .||. | |. .| .|.|| |..|.| |. ..| ..||. .|.|| ralkkfndeekvkafkeaqeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliek GKVKCDQYWPDDHMPVL---YGDIQVTM----NQTFEEND-WNIKEFAVQLR---DQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKppssAPVA ||.|| .|.| . ..| .. ..|. . . |.| .||. ... .. | |.|... |||.|||. | | .. ..|. | .|.. gkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk----gPiv VHC ||| vhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.R_Nematode_2.PD | 1080-1263 | 27 | 8.7e-32 | 101.3 | In-house | 20-200 (261) | Show / Hide |
Range on Protein: 1080-1263 Range on HMM: 20-200/261 Sequence Identity: 27% (52 aa) KMTTNTAVspANVGKNRYTNILPYDRTRVKLspVDDEEGSDyINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQY ..|...| .. |.|| .. ..|.|. . |.. .. | .|..| . |. .|| |||| |..| | |. ..| ..||..| ||| | ||..| svtesaay--lpkdkhRypdvPCkpetavev--ivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeY WPDDHM-PVLYGDIQVTMNQT--FEENDWNIKEFAVQLRDQ---RRYVRHWNFLSWPDHGVPESSQALLAFIRRIRStkppSSAPVAVHC .| .. . | ..... .. ... . . . |. . | |.|. . .|||.|||.|. | . .. | |. ||| fpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkk----sekPivvhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Nematode_4.PD | 1069-1263 | 27 | 5.1e-31 | 98.9 | In-house | 4-203 (264) | Show / Hide |
Range on Protein: 1069-1263 Range on HMM: 4-203/264 Sequence Identity: 27% (57 aa) ELTRAIRKVGRKMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEegSDYINSNYIPGFtSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQL .||| .| . . . .| .| ||||..|| | ||| | | . ||| .... .||..||||. | .|.| |.... ...|||. .| kltrdfvkgkappnvtasaseknsdknryadilcidetrvvlknrdpd--ndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdl VEKGKVKCDQYWPDDHMP-VLYGDIQVTMNQTFEE--NDWNIKEFAVQLRD-------QRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRStkPPSSAP .|.| || .|.|... | .|. ..|. .. || | .. . | . .. .|.|... |.|. |. ..... ... .. .... | ieegvekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekP VAVHC . ||| ivvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N20.PD | 1084-1263 | 36 | 8.1e-31 | 98.4 | In-house | 19-196 (257) | Show / Hide |
Range on Protein: 1084-1263 Range on HMM: 19-196/257 Sequence Identity: 36% (67 aa) NTAVSPANVGKNRYTNILPYDRTRVKLSpvddeEGSDYINSNYIPGFTSPRE--YIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQYWP |. |.| |||| .||||| ||| | . ||||..|| | ||| |||| | ||.|.|. |.| . |.|. .| |.|| .||| nsgnqpsnreknryrdilpydstrvplg-----kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywp DD-HMPVLYGDIQVTMNQTFEENDWNIKEFAVQLRD--QRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKppSSAPVAVHC . |. ..| ... . . |. | | . . |.. .| ||||| | |..... .|| | .. . |.||| islkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh--ltgpmvvhc |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Nematode_6.PD | 1075-1263 | 31 | 3.3e-29 | 93.0 | In-house | 7-192 (253) | Show / Hide |
Range on Protein: 1075-1263 Range on HMM: 7-192/253 Sequence Identity: 31% (60 aa) RKVGRKMTTNTAVS-PANVGKNRYTNILPYDRTRVKLSpvDDEEgsDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGK .... . ....| . .. .|||||| .|..|.||. |||. || .|.. | || .| .|.|| || ...|.||. |. .||. .|||||| | kdspneaseseataflkfkdrnrytniqCcdagrlkla--dded--fyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgk VKCDQYWPDDHM-PVLYGDIQVTMNQTFEENDWNIKEF---AVQLRDQRRYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKppssAPVAVHC . .| .| .... .. . .. | .. |. |. |.| .. .|||||||.| .. | .. ....| |. ||| eksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdk----kPivvhC |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Fungi_PTP1.PD | 1092-1209 | 35 | 1.4e-26 | 84.2 | In-house | 46-172 (343) | Show / Hide |
Range on Protein: 1092-1209 Range on HMM: 46-172/343 Sequence Identity: 35% (46 aa) VGKNRYTNILPYDRTRVKLS----PVD----DEEGSDYINSNYIPGF------TSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCD ||||.|||||...|||| . | ...||||.||. . ||| |.||| | ||....| . .|. ....|..|| . ||..| faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy QYWPDDHmpvlYGDIQVTMNQTFeENDWNIKE |.. | ||.| .... || .|.. rYWqegs----ydditvklaskw-enimgind |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.R_Nematode_3.PD | 1075-1263 | 22 | 8e-22 | 68.8 | In-house | 10-205 (267) | Show / Hide |
Range on Protein: 1075-1263
Range on HMM: 10-205/267
Sequence Identity: 22% (45 aa)
RKVGRKMTTNTAvspANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPgFTSPREYIACQGPL--------PGTTDDMWRMIWEQNVTTVVMVT
.|...|..|.. ..| ..|..... . |||.| .|.|. |.. . . . | |.|. | .| || ...|. |||. .
aklakknatsls---kkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlc
QLVE---KGKVKCDQYWPDDHMPV-LYGDIQVT--MNQTFEENDWNIKEFAVQLRDQR-RYVRHWNFLSWPDHGVPESSQALLAFIRRIRSTKppssAPV
|| ... || .|.|.. . ....|. ... ..| . ... |.. .. |.|. .|.....||... .|. |. ... | .|| |||
dfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveksk----tpv
AVHC
vVHC
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Nematode_5.PD | 1090-1263 | 23 | 1.1e-19 | 61.6 | In-house | 24-197 (258) | Show / Hide |
Range on Protein: 1090-1263 Range on HMM: 24-197/258 Sequence Identity: 23% (41 aa) ANVGKNRYTNILPYDRTRVklsPVDDEEgSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCdQYWPDDHMP-VL .|. |||.... .| ||| . ||. ..||| ..| . ...| | ||| |. |.|||. ....|.||.... |. .. ...|. . .| knlkknrskdvkilDetrV---kltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdyln YGDIQVTMNQTFE---E-NDWNIKEFAVQLRDQrRYVRHWNFLSWPDHGVPESSQALLA-FIRRIRSTKPPSSAPVAVHC .. ... .. . | . .... .. . .. ... .. |... ||........ | .. |.| ..||| |.. lgkmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvs |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Nematode_eak.PD | 1082-1251 | 21 | 6e-19 | 59.3 | In-house | 17-185 (281) | Show / Hide |
Range on Protein: 1082-1251 Range on HMM: 17-185/281 Sequence Identity: 21% (37 aa) TTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEeGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQYWP . . . .| .|| .|.|.|| |.|.. . |||. . |.|| . .|.|. ||. ..|.. . ||.. | |.|.| sirvtarleavnrnrvvkivpqdrylvrltssqln-rdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfp DDHMPVLYGDIQVTMNQT-FEENDWNIKEFAVQLRDQRRYVRHWNFLSWPDHGVPESsQALLAFIRRIRST |. . || ..|. . ..| . . . .. .. | |... | . .| ..||. . .. . dktevlkyGildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpky-edflalrkvmkev |
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| Phosphatase | Spur_PTPRB8.AA | Subfamily.N_Nematode_egg.PD | 1080-1226 | 24 | 7.5e-19 | 59.1 | In-house | 15-165 (257) | Show / Hide |
Range on Protein: 1080-1226
Range on HMM: 15-165/257
Sequence Identity: 24% (37 aa)
KMTTNTAVSPANVGKNRYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPGFTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKgkVKCDQY
... .||.| . | | . . .|||| |.| .|.. | |.| .| || | .|.|||.....|.||.| .| .|. |||
eislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyy
WPD---DHMPVLYGDIQVTMNQTFEENDW--NIKEFAV-QLRDQRRYVRHWNF
. . .. | .... . .. | .. .. . |. ... ||.
wpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Spur_PTPRB8.AA | Protein | None | 1263 | None | Fasta, JSON |
| Spur_PTPRB8.NA | RNA | None | 3789 | None | Fasta, JSON |
| Spur_PTPRB8.AA.PD_1066-1263 | Protein Phosphatase Domain | None | 198 | None | Fasta, JSON |