• Phosphatome.Net

Gene Spur_PTPRB10

Spur_PTPRB10
Species: S.purpuratus
Alias: Spur_hmm56155, Spur_PTPRB10, hmm145625
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RB
Protein domain

Protein domains of Spur_PTPRB10.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Spur_PTPRB10.AA Subfamily.RB.PD 1-59 62 6.7e-31 98.6 In-house 202-260 (261) Show / Hide 
Range on Protein: 1-59
Range on HMM: 202-260/261
Sequence Identity: 62% (37 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
|||||||||| ||..||..|. |.|||.|||. .|..||..||||.||.|||.||.|..
aGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll
Phosphatase Spur_PTPRB10.AA Y_phosphatase 1-57 47 2.6e-25 90.11 Pfam 187-243 (243) Show / Hide 
Range on Protein: 1-57
Range on HMM: 187-243/243
Sequence Identity: 47% (27 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMD
||.||||||...| ..|.||. . ||....|. || .|..|||||.||.|...|...
AGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase Spur_PTPRB10.AA Subfamily.R_Anemone_2.PD 1-59 45 1.6e-21 68.0 In-house 203-261 (262) Show / Hide 
Range on Protein: 1-59
Range on HMM: 203-261/262
Sequence Identity: 45% (27 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
|||||||.||..| .|.....   |||...|  .| .|| ||||..||.||.  |.. .
aGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase Spur_PTPRB10.AA Subfamily.N5_RR.PD 1-56 44 3.5e-20 63.4 In-house 206-261 (265) Show / Hide 
Range on Protein: 1-56
Range on HMM: 206-261/265
Sequence Identity: 44% (25 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLM
||.|||| ||  .. ......  .|||...|| .|..|  ||||..|| .||| |.
aGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc
Phosphatase Spur_PTPRB10.AA Subfamily.N_Choan_1.PD 1-59 45 6.9e-20 62.5 In-house 202-261 (262) Show / Hide 
Range on Protein: 1-59
Range on HMM: 202-261/262
Sequence Identity: 45% (27 aa)

AGVGRTGTFIVLDNILQHMEQ-YDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
||||||||.| || .....|.  . .||  ||  .| .||.||||  || |......|..
aGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal
Phosphatase Spur_PTPRB10.AA Subfamily.RA.PD 1-59 49 3.2e-19 60.3 In-house 207-265 (266) Show / Hide 
Range on Protein: 1-59
Range on HMM: 207-265/266
Sequence Identity: 49% (29 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
|||||||||||||..|. ..  . .||...|  .|. |  ||||..||.||.. |.. |
aGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi
Phosphatase Spur_PTPRB10.AA Subfamily.R_Ecdysozoa.PD 1-59 45 1e-18 58.4 In-house 210-268 (269) Show / Hide 
Range on Protein: 1-59
Range on HMM: 210-268/269
Sequence Identity: 45% (27 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
|||||.|.|. || .||.... | ||.. .|...| .||..||  .||||..| |.| .
aGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyraladys
Phosphatase Spur_PTPRB10.AA Subfamily.R_Sponge_2.PD 1-59 45 3e-18 57.2 In-house 203-261 (262) Show / Hide 
Range on Protein: 1-59
Range on HMM: 203-261/262
Sequence Identity: 45% (27 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
.|||||||||.|| .|..... . .||  |. ..|..|...||...||||||  | ..|
dgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi
Phosphatase Spur_PTPRB10.AA Subfamily.R_Anemone_1.PD 1-57 45 4.4e-18 56.8 In-house 199-255 (258) Show / Hide 
Range on Protein: 1-57
Range on HMM: 199-255/258
Sequence Identity: 45% (26 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMD
|||||||.|.|.| .|... .   ||.. .|  .| .|  ||||..||||||. ...
aGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavle
Phosphatase Spur_PTPRB10.AA Subfamily.RG.PD 1-59 45 2.8e-17 54.0 In-house 205-263 (264) Show / Hide 
Range on Protein: 1-59
Range on HMM: 205-263/264
Sequence Identity: 45% (27 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
|||||.||.|.|| .||..|. . |.| .|.  .|..|...|.|| |||||.  |....
aGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallelv
Phosphatase Spur_PTPRB10.AA Subfamily.N9.PD 1-57 43 5.4e-17 53.1 In-house 216-272 (275) Show / Hide 
Range on Protein: 1-57
Range on HMM: 216-272/275
Sequence Identity: 43% (25 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMD
||.||||||| ||  |...|. . |||. .|  .|  | |..||..||.| . ....
aGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
Phosphatase Spur_PTPRB10.AA Subfamily.RC.PD 1-57 38 1.6e-16 51.3 In-house 229-285 (288) Show / Hide 
Range on Protein: 1-57
Range on HMM: 229-285/288
Sequence Identity: 38% (22 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMD
.|..|||.|| |...|. .|  . ||| .||  .|  |  ||..|.||....  |..
dGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve
Phosphatase Spur_PTPRB10.AA Subfamily.N12.PD 1-59 32 1.6e-16 51.2 In-house 208-269 (270) Show / Hide 
Range on Protein: 1-59
Range on HMM: 208-269/270
Sequence Identity: 32% (20 aa)

AGVGRTGTFIVLDNILQHMEQYDF---VDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
|||||||| |..| . . ...      .||  .|  .| .|. .|||..||...........
aGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
Phosphatase Spur_PTPRB10.AA Subfamily.N_Choan_2.PD 1-59 33 3.4e-16 50.1 In-house 207-265 (266) Show / Hide 
Range on Protein: 1-59
Range on HMM: 207-265/266
Sequence Identity: 33% (20 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
||||||||.|..| ... .|.   |||. ..  .| .|  .||. .|| .... ... .
aGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya
Phosphatase Spur_PTPRB10.AA Subfamily.N13.PD 1-59 35 5.7e-16 49.7 In-house 200-258 (259) Show / Hide 
Range on Protein: 1-59
Range on HMM: 200-258/259
Sequence Identity: 35% (21 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
||.||.|..|..| .|. .|.   .||  .|  .|  |. .|||..||.|... ...|.
aGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
Phosphatase Spur_PTPRB10.AA Subfamily.RK.PD 1-58 40 5.7e-15 46.1 In-house 208-265 (267) Show / Hide 
Range on Protein: 1-58
Range on HMM: 208-265/267
Sequence Identity: 40% (23 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDV
|| ||.||||..| .|. .|. . |||  .|  .| ..  ||.||.||.|..   .. 
aGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea
Phosphatase Spur_PTPRB10.AA Subfamily.N_Nematode_6.PD 1-58 40 1.5e-14 45.0 In-house 194-251 (253) Show / Hide 
Range on Protein: 1-58
Range on HMM: 194-251/253
Sequence Identity: 40% (23 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDV
||||||||....  ||. . . || .|  ..  .|  |   |||| ||.. .||... 
aGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvley
Phosphatase Spur_PTPRB10.AA Subfamily.N_Nematode_1.PD 1-58 37 1.9e-14 44.5 In-house 205-263 (265) Show / Hide 
Range on Protein: 1-58
Range on HMM: 205-263/265
Sequence Identity: 37% (22 aa)

AGVGRTGTFIVLDNILQHMEQYDFV-DVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDV
||.||||| .... ||... . . . |.  .|  .| .||. .||..||.|.|| |.. 
aGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny
Phosphatase Spur_PTPRB10.AA Subfamily.N6.PD 1-59 40 6.3e-14 42.9 In-house 233-294 (295) Show / Hide 
Range on Protein: 1-59
Range on HMM: 233-294/295
Sequence Identity: 40% (25 aa)

AGVGRTGTFIVLDNILQHMEQYDF---VDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
||.||||||||.| .|. .||  .   .|.  ..  .|..|  .||||.|| |. ....  |
aGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi
Phosphatase Spur_PTPRB10.AA Subfamily.N3.PD 1-58 36 8e-14 42.4 In-house 202-259 (261) Show / Hide 
Range on Protein: 1-58
Range on HMM: 202-259/261
Sequence Identity: 36% (21 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDV
||.|||| .|.|.  |. .|. . | .. .|  ||  |  .|||..|| |.  ... .
aGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka
Phosphatase Spur_PTPRB10.AA Subfamily.N14.PD 1-59 35 1.9e-11 34.6 In-house 216-274 (275) Show / Hide 
Range on Protein: 1-59
Range on HMM: 216-274/275
Sequence Identity: 35% (21 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
|||||||  |. | ... .|. . .|.  |.  .|  | ..|||  || |... |.  .
aGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl
Phosphatase Spur_PTPRB10.AA Subfamily.N_Nematode_4.PD 1-58 29 4e-11 33.7 In-house 205-262 (264) Show / Hide 
Range on Protein: 1-58
Range on HMM: 205-262/264
Sequence Identity: 29% (17 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDV
|||||| |.. .|   ... .   ..|. .|  .|  |   ||.. |..|.  .|.. 
aGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvliel
Phosphatase Spur_PTPRB10.AA Subfamily.RN.PD 1-57 25 2.4e-10 31.0 In-house 204-261 (264) Show / Hide 
Range on Protein: 1-57
Range on HMM: 204-261/264
Sequence Identity: 25% (15 aa)

AGVGRTGTFIVLDNILQHMEQ-YDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMD
.|.||||..|..| .|... .    .|..  .  .|  |. .|.|..|. |.  .. .
dGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
Phosphatase Spur_PTPRB10.AA Subfamily.N20.PD 1-59 35 2.5e-10 31.3 In-house 198-256 (257) Show / Hide 
Range on Protein: 1-59
Range on HMM: 198-256/257
Sequence Identity: 35% (21 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
||.|||| |...| ..  . .   ...| .|. || .|. ||||..|| | .  ...|.
agigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl
Phosphatase Spur_PTPRB10.AA Subfamily.R_Nematode_2.PD 1-56 26 4.8e-10 30.1 In-house 202-257 (261) Show / Hide 
Range on Protein: 1-56
Range on HMM: 202-257/261
Sequence Identity: 26% (15 aa)

AGVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLM
||.|||..||  . . ...|. . . .   .  .| ||   .|||.|. .... ..
aGiGRtmafigteylareveadptieltealkelrehRwkgiqtesqlywltlgal
Phosphatase Spur_PTPRB10.AA Subfamily.N1.PD 1-55 31 5e-10 30.2 In-house 206-263 (268) Show / Hide 
Range on Protein: 1-55
Range on HMM: 206-263/268
Sequence Identity: 31% (18 aa)

AGVGRTGTFIVLDNILQHMEQYDF---VDVMGVVCGMRMHRNFMVQTEQQYVFIHRCL
||.||.||. ..|..| ..|...    ||.  |.. .| .|  ..|| .|  |    .
agigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiai
Phosphatase Spur_PTPRB10.AA Subfamily.N23.PD 1-55 31 9.3e-10 29.0 In-house 290-345 (350) Show / Hide 
Range on Protein: 1-55
Range on HMM: 290-345/350
Sequence Identity: 31% (17 aa)

AGVGRTGTFIVLDNILQHME-QYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCL
||||||||| |.  ... .. .   .... ||  .|  | .|||..... .. .  
aGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeav
Phosphatase Spur_PTPRB10.AA Subfamily.R_Nematode_3.PD 1-58 18 1.2e-09 28.8 In-house 207-265 (267) Show / Hide 
Range on Protein: 1-58
Range on HMM: 207-265/267
Sequence Identity: 18% (11 aa)

AGVGRTGTFIVLDNILQHMEQYD-FVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDV
.|..|..|. . .   | . . .  .|.. ... .| .|   .|||... |.  .....
dGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkl
Phosphatase Spur_PTPRB10.AA Subfamily.N_Nematode_5.PD 2-58 23 3.9e-09 27.0 In-house 200-256 (258) Show / Hide 
Range on Protein: 2-58
Range on HMM: 200-256/258
Sequence Identity: 23% (13 aa)

GVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDV
|.||.|||..|. . . ...   ...  ..  .|  |  .|.. .||........| 
GlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldy
Phosphatase Spur_PTPRB10.AA Subfamily.N_Fungi_PTP1.PD 1-56 33 5.8e-09 26.3 In-house 269-339 (343) Show / Hide 
Range on Protein: 1-56
Range on HMM: 269-339/343
Sequence Identity: 33% (24 aa)

AGVGRTGTFIVLDNILQHMEQY----------DFV----D-VMGVVCGMRMHRNFMVQTEQQYVFIHRCLM
||||||||.. || .|...| .          |      | .  .|  .| .|  |||. .|..||. .|.
aGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall
Phosphatase Spur_PTPRB10.AA PTPc_motif 1-57 29 6e-06 18.05 SMART 13-92 (92) Show / Hide 
Range on Protein: 1-57
Range on HMM: 13-92/92
Sequence Identity: 29% (25 aa)

A-----------------------------GVGRTGTFIVLDNILQHMEQYDFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMD
                              |.||||||...| ..|.      ||. ..|. ||..|..|||||.||.|..||...
HVEKDSGVPEDSILEFIRHVRKPIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE
Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPRB10.AA Protein None 75 None Fasta, JSON
Spur_PTPRB10.NA RNA None 225 None Fasta, JSON
Spur_PTPRB10.AA.PD_1-57 Protein Phosphatase Domain None 57 None Fasta, JSON