• Phosphatome.Net

Gene Spur_PTPRD2

Spur_PTPRD2
Species: S.purpuratus
Alias: Spur_PTPRD2, Spur_hmm87353, hmm56190
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RD
Protein domain

Protein domains of Spur_PTPRD2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Spur_PTPRD2.AA Subfamily.N6.PD 23-280 40 1.9e-77 252.1 In-house 10-291 (295) Show / Hide 
Range on Protein: 23-280
Range on HMM: 10-291/295
Sequence Identity: 40% (115 aa)

DAMLFSQEYESIE---PGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPM-EGLPGSDYTNANYCD--------GYR-----KQNAYIATQGPLLET
... |..|.|...     .... ....  .|| |||| |.. .||.||||.   . .||||| |||| .        |       .|. ||||||.| .|
qtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdt

MADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRD-QEKYGFIQVTLLDTTELATYTVRSFALV-KNRSMEKREVKQFQFTAWPDHGVPEHATSVLA
..|||||||.. .. |||.||  ||.. || .|||..  ....| |.|| .. .. |.||.| | .  |.   |.||. |..|.||||||||...  || 
vsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvln

FISRVKSCN--PPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEK---TVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
|.. |.. .    .|||||||||||.||||..|||| .|. |....    .||.  .. .|.||  .||||.||.|.  |. 
fledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq
Phosphatase Spur_PTPRD2.AA Y_phosphatase 50-281 48 1.2e-133 455.05 Pfam 1-243 (243) Show / Hide 
Range on Protein: 50-281
Range on HMM: 1-243/243
Sequence Identity: 48% (119 aa)

NKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDG-YRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNR-VK-CDQYWPT---RD
||.|||| ....|||.||.|.|..| ..||| |||| || |....|||.||||. .|..|||||||.|.. .|||.....|..| .| |.||||.    .
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

QEKYGFIQVTLLDTTELATYTVRSFALVKNRS--MEKREVKQFQFTAWPDHGVPEH-ATSVLAFISRVKSCNP-PDAG--PIVVHCSAGVGRTGAYIVID
 ..|| .|||. ...... |||| | . .  .   |.|.|.....|.||||||||. ..|.| || .|....| ||.|  |||||||||.||||....||
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

SMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
 |.....||.||||.. | ..|.||..||||||||||..... |
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase Spur_PTPRD2.AA PTPc 26-284 37 1.2e-129 437.88 SMART 1-308 (308) Show / Hide 
Range on Protein: 26-284
Range on HMM: 1-308/308
Sequence Identity: 37% (116 aa)

LFSQEYESIEPGQQF----------TWDHSNLETNK--PKNRYA-NVIAYDHSRVILSPMEGL----PGSDYTNANYCDGYRKQNAYIATQGPLLETMAD
 |..|.|...  ..           ........ |.   ||||  ....|||.||.|.| .|     .|||| |||| |||.....||.||||| .| .|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMVWEQRTNTIVMMTKLEER--------NRVKCDQYWPTRDQEKYGFIQVTLLDTTELA-TYTVRSFALVKNRS--------MEKREVKQFQFTAWPD
||||||.|.. .|||.....|.        .|.||.||||    ..|| |.||..... ..  ||.| | . .            |.|.|.....|.|||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

HGVPEHATSVLAFISRVKSCNPPD-------------------AGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQY
|||||...|.|.|| .|.....                     .||||||||||.||||....|| |...|..   |||.. |  .| ||..||||||||
HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY

IFIHEALYEAVA
||..... | . 
IFCYRCILEYIK
Phosphatase Spur_PTPRD2.AA Subfamily.R_Anemone_2.PD 27-283 50 8.60000000001e-116 377.7 In-house 2-261 (262) Show / Hide 
Range on Protein: 27-283
Range on HMM: 2-261/262
Sequence Identity: 50% (132 aa)

FSQEYESIEPGQQ--FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMM
.|.||| ... ..  .|..... ..|| ||||||..|||..|| |...|| .|||| |||| ||||...||||||.|| ||. ||||||||| . .|||.
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TKLEERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCN-PPDAGPIVVHC
|..||| ..|...||| .. ..|| ..|.| ...||..|..||| . .... |.|.|.||..|.|||.||||...|.|... .|.. . ...||||||||
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhc

SAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
|||||||| .|..|..|||||.|..||... |. || ||| ||||..||.||...| ||.
saGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase Spur_PTPRD2.AA Subfamily.R_Anemone_1.PD 27-283 47 3.6e-105 343.0 In-house 2-257 (258) Show / Hide 
Range on Protein: 27-283
Range on HMM: 2-257/258
Sequence Identity: 47% (122 aa)

FSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTK
...|.. .. ....... .. ..|| |||||...|.|||||.|. ... . ||| || | ....|..|.||||.|| ||..|||||||.... .|||.| 
yaaefqrlkeikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtn

LEERNRVKCDQYWPTrDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAG
|.| .  || ||||.  .|||| ..|.|  . . | |..|...| |... |.||| |..|| |||.|||..||.||.. ..|.. . ..| |.|||||||
liegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaG

VGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
||||||..|||.|||..|.||.|||.  |. .| .| .||||.|||.|||.|..||.
vgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal
Phosphatase Spur_PTPRD2.AA Subfamily.RG.PD 27-283 44 7.50000000001e-101 328.7 In-house 2-263 (264) Show / Hide 
Range on Protein: 27-283
Range on HMM: 2-263/264
Sequence Identity: 44% (116 aa)

FSQEYESIEP--GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMM
.....| |     .... ..|. |.|| |||..|..|...||| |||. |  |.|| ||.| ||||....||.||||| ||. |||||.||.....|||.
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TKLEERNRVKCDQYWPT-RDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKRE--VKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVV
|.|.|. | ..|.|||.  . .... ..||||....|..||||.| | ...  ...|  |.|...| |||.|.||... || |. . ..|. .|||||||
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivv

HCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
.||||||.| ||..|..|.....|..|..|. .  .||.|...|.|||||.||..|| |.| 
hdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallelv
Phosphatase Spur_PTPRD2.AA Subfamily.R_Sponge_2.PD 27-283 45 1.3e-99 324.6 In-house 2-261 (262) Show / Hide 
Range on Protein: 27-283
Range on HMM: 2-261/262
Sequence Identity: 45% (118 aa)

FSQEYESIEPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPmEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTK
. .|..|.|  ..|. . ..|..|..|||......||.||| |.. .| ..||| ||.. |||....||||||||| ||..||||||||....||||.|.
leeeeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltn

LEERNRVKCDQYWPTR--DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSME-KREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNP-PDAGPIVVH
|||... || .|||..  .. .|| ..||| ....|| |..| . | |..| | ...|.||.|.|||.|.||..|||.|..|.||.  .     ..|.|.
leengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvv

CSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
||.||||||..|..||.|||.|.|...|..  .  || .|...||...|| |||.|||.. 
CsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi
Phosphatase Spur_PTPRD2.AA Subfamily.RB.PD 27-282 48 2.8e-98 320.2 In-house 2-259 (261) Show / Hide 
Range on Protein: 27-282
Range on HMM: 2-259/261
Sequence Identity: 48% (123 aa)

FSQEYESIEP-GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMT
||.|||...  |.. . .......|. |||. |...|||||| |. ..  ...|| |||| .||.... |||||||| ||. ||||||||.....|||.|
fseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

KLEERNRVKCDQYWPTRD-QEKYGFIQVTLLDTTELATYTVRSFALVKnrSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPD--AGPIVVH
.| |. ..||..|||. . .  || |.|||| ..|| ....|.|.. |   .|||.|.|..||.||||||||.....|.|. .|...  ..|||||||||
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvH

CSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
|||||..| .| .|..|... .||..| |. || .||..||||.|||||||.| .     
CsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl
Phosphatase Spur_PTPRD2.AA Subfamily.RA.PD 40-281 49 3.9e-98 319.7 In-house 17-263 (266) Show / Hide 
Range on Protein: 40-281
Range on HMM: 17-263/266
Sequence Identity: 49% (122 aa)

FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYW
. . .|.| || |||. ... ||.|||||| .|| . ||| || . ||||... .||.|||. ||. |||||.|||.. ||||.|.|.||..|| ||||.
eklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqyw

PTRDQEKYGFIQVTLLDTTELATYTVRSFALV----KNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAG-PIVVHCSAGVGRTGAYI
     || |.|.. |.|.| .|||| | .     . |  ..| |.|| ||.||. ||| ..  .| .. .||....  |. ||||||||||||||..||.
pdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfi

VIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
|..|||.| |. .|... |  ||.||  ||||.||| ||...| |  
vldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle
Phosphatase Spur_PTPRD2.AA Subfamily.RK.PD 27-283 41 8.5e-97 315.2 In-house 2-266 (267) Show / Hide 
Range on Protein: 27-283
Range on HMM: 2-266/267
Sequence Identity: 41% (110 aa)

FSQEYESI----EPGQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLpGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIV
. .|.|..      .|.  .| . .. |. |||. ...|||.|.|.| ...|   ||| ||.. |.|.. .|.|.||||| ||..||||.|..... .||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MMTKL-EERNRVKCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVK--NRSMEKREVKQFQFTAWPDH-GVPEHATSVLAFISRVKSCNPP-DAG
|.|.|  |. |||| .|||   . .|| |.|.|.... .| . || |.. |      |.|||.||||..||.. .||....|.|..||||. ... ..|.
mlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeG

PIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
|||||.|| ||.|..|.||..|| |..|..||..  |  ||...  ||.|||||.|....  ||. 
rivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal
Phosphatase Spur_PTPRD2.AA Subfamily.N_Choan_1.PD 27-282 41 4.9e-87 283.3 In-house 2-260 (262) Show / Hide 
Range on Protein: 27-282
Range on HMM: 2-260/262
Sequence Identity: 41% (109 aa)

FSQEYESIEP-GQQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMT
| .|||...  |.. |   |. . |. ||||.|..|||..|| ..| |    .|| |||...||.....|||||||. .....||.|||||. ..|||.|
fieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvt

KLEERNRVKCDQYWPTRD-QEKYGFIQVTLLDTTELATYTVRSFALvKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDA-GPIVVHC
.  | ...|| .|||  . . |.| ..|. | ..| .||  | | | ...| |.|||.|...|||||||||. .. .| | . |.... ..   |.|.||
reieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihC

SAGVGRTGAYIVIDSMLERIKHEKTV-DIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
||||||||.|| .| ........... |.   |. || .||.||||  || |.. |. .|
saGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda
Phosphatase Spur_PTPRD2.AA Subfamily.N9.PD 29-281 43 5.8e-87 283.3 In-house 4-272 (275) Show / Hide 
Range on Protein: 29-281
Range on HMM: 4-272/275
Sequence Identity: 43% (111 aa)

QEYESIEPG-QQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKL
.||..|     . | ..|.| .|  ||||..|. ||..|| |. ... . ||| |||..|||....|.||||||| .|. |||||||||.. .|||.|..
keyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrv

EERNRVKCDQYWP--TRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSC-------------N
.||.|.|| ||||  . .....|...|. ... .   |.||.. . . .. |.|.|  |||..|||.|||. |.|.| ....|.....  |||||||||.
vergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskg

PPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
||||..| .|  |.|.... |||.   |  ||.|| ...||.||| | . |. |               
hlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
Phosphatase Spur_PTPRD2.AA Subfamily.R_Ecdysozoa.PD 27-281 38 7.6e-83 269.4 In-house 2-266 (269) Show / Hide 
Range on Protein: 27-281
Range on HMM: 2-266/269
Sequence Identity: 38% (103 aa)

FSQEYESIEPG--QQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMM
. .|||..|     . .   |. . |. |||| ...|.|. ||.|....|   ||| ||..  ||.... .|| |.|. .|. |||||..||  ..|||.
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TKLEERNRVkCDQYWPTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNR--S-MEKREVKQFQFTAWP-DHGVPEHATSVLAFISRVKSCNPPD-----
..|.| ||  |..|||  |. .|| | |.| .. .   |. |.. . |.   |  ..|.| |...|.|.|  |||.|...| .|..|.. .  .      
snlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgs

AGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
.||||||||||||.| .. .|..|...| |..|||.  |  || ||| .||  |||.|.. || . 
rsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad
Phosphatase Spur_PTPRD2.AA Subfamily.N12.PD 38-283 41 4.2e-78 253.9 In-house 20-269 (270) Show / Hide 
Range on Protein: 38-283
Range on HMM: 20-269/270
Sequence Identity: 41% (105 aa)

QQFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQ
.... .... |.|. |||| ... ||.|||.|| .|. .|||| |||.  | ... .|||.|||| .|. |||||.||.... .||. .. |.. ||..|
kvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer

YWPTRDQEK--YGFIQVTLLDTTELA-TYTVRSFALVKNrsMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYI
|| . .|.  .| ..||| .   .   ...|.... ..   |.|.|.||..|||||||||. |.|.|..|. |.. .  .. |.||||||||||||. |.
yWpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtii

VIDSMLERIKHEKT---VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
|| . | .|.||.   .|..  |. || ||. .|||.||| ....|. | | 
aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
Phosphatase Spur_PTPRD2.AA Subfamily.N5_RR.PD 42-281 39 5.2e-76 247.2 In-house 15-262 (265) Show / Hide 
Range on Protein: 42-281
Range on HMM: 15-262/265
Sequence Identity: 39% (95 aa)

WDHSNLETNKPKNRYANVIAYDHSRVILSPMEGL-PGSDYTNANYCDGYRK-QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYW
.. ..  .. |||| ...  ..|||.|.. ..  . |.| ||||  ||.. ..||.|||||| .|.||||||....... |||.|||.|.|| || .|.|
qeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyf

PTRD----QEKYGFIQVTLLDTTELATYTVRSFALVKNRSmEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCN---PPDAGPIVVHCSAGVGRTGA
..     .|.|| ....  ...|   |.||.. | . ..  .|.|| . .|.|||| .|......| ..  |.. ...|.|||||||.||||..| |.  
Pdaedyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGc

YIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
. ....|..||. . |. || .|  ||||.||| .||.||..       
fiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
Phosphatase Spur_PTPRD2.AA Subfamily.N6.PD 309-574 39 1.4e-75 246.0 In-house 9-294 (295) Show / Hide 
Range on Protein: 309-574
Range on HMM: 9-294/295
Sequence Identity: 39% (111 aa)

ETITGMENEFKRLASQKAQPS-RFVSANIPANKFKNRLLNIQPYEGNRVCLQPI-RGVEGSDYINASHI--------DGYRQ-----RNAYIATQGPLAE
|...||..|  |...      ... . || |||  || |.. .|| |.   . | |||||||..|        .|  .      . ||||||.| .| .|
sqtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkd

TTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAER-SARYQYFVVDPMSEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKSGEGFI
|||| |..||..|||. |  | |..|| .|||.|. . ..    |  .|| .. .|.||||.|.    | ..|.|.|..|. ||..||||. . ...|. 
tvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvl

DFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGI---VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
.|.|..|.. ..||| ||||||.|||| || . .||. .. .|.   .|. ...|..|.||  .||||.||.| |.|.|.      
nfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi
Phosphatase Spur_PTPRD2.AA Subfamily.N3.PD 40-282 41 4e-75 244.1 In-house 16-259 (261) Show / Hide 
Range on Protein: 40-282
Range on HMM: 16-259/261
Sequence Identity: 41% (102 aa)

FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEglPgsDYTNANYCD----GYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKC
.. .....  | .|||| ....||. ||.|.  |     || |||| .    .    | |||||||| .|..|||.|||||....|||.| | || ||||
laisaarkpenlaknryrdilpydatrvklkese--t--dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkC

DQYWPTR-DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYI
 ||||.  |. ..| ..|..  . |  .| .| . | .... |.|.. |.|..||||||||......| |..||...   .  |.|||||||.|||| .|
hqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvli

VIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
...  |  | ... | .   |  .| ||  .|||..|| |. ||. .|
lletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka
Phosphatase Spur_PTPRD2.AA Subfamily.N13.PD 43-282 42 4.5e-75 244.2 In-house 19-257 (259) Show / Hide 
Range on Protein: 43-282
Range on HMM: 19-257/259
Sequence Identity: 42% (105 aa)

DHSNLETNKPKNRYANVIAYDHSRVILSPMEGlpgsdYTNANYCDGYRK--QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWP
. .. . || |||| ||. ||..||.|.   |     | ||..        .  |||.|||| ||..|||.|||||... |.|.|.  |...|||..|||
evgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywP

TRDQEK---YGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPpDAGPIVVHCSAGVGRTGAYIVID
 | ..|   .. ..|.||....| ...||..|. ...| | ||| ...|..||||||| .|.... |...|.. .  ||||||||||||.||.|..|.||
erknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvhcsaGiGrsGvlitid

SMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEA
 .|. |...| .|.   | .|| ||. .|||..||||...|. |.
vvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailev
Phosphatase Spur_PTPRD2.AA Subfamily.RC.PD 39-281 35 7.3e-73 237.0 In-house 15-285 (288) Show / Hide 
Range on Protein: 39-281
Range on HMM: 15-285/288
Sequence Identity: 35% (97 aa)

QFTWDHSNLETNKPKNRYANVIAYDHSRVIL-------------------SPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTN
..|   .. | || ||||..|. ||. || |                   . ...  ||.| || . |.|.| . |||.|||| ||. |||||..|....
krtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvk

TIVMMTKLEERNRVKCDQYWpTRDQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRV----------K
 |||.|.|.| .| || .||    .. || ..| | ||   ..|..| . ||...  . ||| |.|.|.|.....||.   .| .||          .. 
vivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsse

SCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
.   ..|..|||..|..||| .| ....|| .. |. ||... |  || .|  ||..|||||.....| |  
afknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve
Phosphatase Spur_PTPRD2.AA Subfamily.N_Choan_2.PD 46-281 36 1.1e-65 213.1 In-house 17-263 (266) Show / Hide 
Range on Protein: 46-281
Range on HMM: 17-263/266
Sequence Identity: 36% (91 aa)

NLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQ-NAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ
.  .||  |||....   ..||.|...|  . . | ||||  |. .. ..|||..|||  |. .||||.||.....|||.|.|||..| ||..|||.. .
eyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepk

EKY----GFIQVTLLDTTELATYTVRSFALVKnrSMEKREVKQFQFTAWPDHGVPEHAT------SVLAFISRVKSCNP--PDAGPIVVHCSAGVGRTGA
||     |.|.|. | ..    | ..   | |  . |.|... |....|||||||...       ..|. .  |.  .    .|.|..||||||||||| 
ekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGt

YIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
 |.|| ... ....| ||.   .. || .|  .||. ||| ....|. |
liaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavve
Phosphatase Spur_PTPRD2.AA Subfamily.RN.PD 41-283 44 3.1e-63 205.2 In-house 18-263 (264) Show / Hide 
Range on Protein: 41-283
Range on HMM: 18-263/264
Sequence Identity: 44% (109 aa)

TWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANY-CDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYW
| . .. | |  |||...|..|||||| |.       ||| ||    |   .. ||||||||| .|.||||.||||| .  ||..|.||| ..|..||| 
tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckryw

PTRDQEKYGFIQVTLLDTT-ELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDS
  .| |.. .| |.        | |||| |   .. | | | || | .||..|||  | |.| |  .|  .    . |||||||.|.||||.||.|| .|
pdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidl

MLERI-KHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYEAV
||. |  | .||   .  || ||. .|.|..|. |.  |. | |  
vlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev
Phosphatase Spur_PTPRD2.AA Subfamily.N14.PD 29-280 35 2.1e-61 199.3 In-house 4-271 (275) Show / Hide 
Range on Protein: 29-280
Range on HMM: 4-271/275
Sequence Identity: 35% (94 aa)

QEYESIEPGQQ-FTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLpGSDYTNANYCDG--YRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMT
.||| | . ..  . . ..|. |..|||. .|. |...|| ||| .    ..| ||         |.  ||..|||| .|. |||.||||| .. |||.|
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

KLEERNRVKCDQYWPTR----DQEKYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCN-------PP
. ||  . |. .|.|      .. ..|  .||   ...  ... ... |    | |.|.|  .|.| ||||||||  .. | |. .|.|         ..
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseves

---DAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
      |..|||||||||||  |. | ... ..|....||   .. || || ..|||  || |....| 
vkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvli
Phosphatase Spur_PTPRD2.AA Subfamily.N1.PD 39-281 35 1.5e-58 190.0 In-house 17-265 (268) Show / Hide 
Range on Protein: 39-281
Range on HMM: 17-265/268
Sequence Identity: 35% (89 aa)

QFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGlpgsDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQY
..   ...|..|...||| .|  |||||..|   .     || ||.  .  . .  || ||||| .|.  ||.||||| . ...|. |. |.|..|| ||
eletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy

WPTRDQE---KYGF--IQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKS--CNPPDAGPIVVHCSAGVGRTG
||. ..|   ..    ..|.|. . .   ..|| . |   .. | ||. .|..| ||| ||||  ...| |. .|..  .  .| ||.|.|||||.||.|
wpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsg

AYIVIDSMLERIKHEKT---VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
.. ..|..| .| ...    |||  ..  || .|  ..|| .|  |   |. |
tlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile
Phosphatase Spur_PTPRD2.AA Subfamily.N23.PD 63-281 35 1e-56 184.1 In-house 115-347 (350) Show / Hide 
Range on Protein: 63-281
Range on HMM: 115-347/350
Sequence Identity: 35% (83 aa)

DHSRVILSP-MEGLPGSDYTNANYCDGYRK-QNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ--EKYGFIQVTLLDTT
|..|| |    .    .|| || |          .||||||. .|.|||| |||||....|||.|| .|.|. |||||||..    ...| ..|.| ...
dpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslr

ELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCN----PPDA-----GPIVVHCSAGVGRTGAYIVIDSMLERIKHE-KT
.  ..  | . | .|    .|.|.....|.|...|||.   ..|||.  |...       ..      ||..||||||||||.. |. | .. ....   
ssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngi

VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
..|   |  ||.|| ||||..... .. ||  |
iniprvvrrlrqqRkymvqkkvilkklyeavle
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_1.PD 48-280 35 4.8e-55 178.4 In-house 24-261 (265) Show / Hide 
Range on Protein: 48-280
Range on HMM: 24-261/265
Sequence Identity: 35% (87 aa)

ETNKPKNRYANVIAYDHSRVILSpMEGLPgSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKY
.... ||||..|   |..||.|.  |.|| |||  |||     . . .| .|.|| .|.|||| ||  .. ..|||. || |...|| .|.|....||  
aqeadknrykdvgcldknrvkla-eeplp-sdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegekl

GFIQV----TL-----LDTTELATYTVRSFALV-KNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKscnpPDAGPIVVHCSAGVGRTGAYIVID
| .     |.      ...| .  ...   |  .    ..|.|...|.| |||.|||.   ..| ....|.    .. ||||||||||.||||. ..|. 
efkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavr----gskgPivvhCsaGiGrtGtivaie

SMLERIKHEKTVD-IYGHVTCLRAQRNYMVQTEEQYIFIHEALY
.|... ..|... .   |  .| |||| .||. ||.|.|  |  
yildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvll
Phosphatase Spur_PTPRD2.AA Subfamily.N20.PD 43-281 37 1.7e-51 166.9 In-house 19-254 (257) Show / Hide 
Range on Protein: 43-281
Range on HMM: 19-254/257
Sequence Identity: 37% (92 aa)

DHSNLETNKPKNRYANVIAYDHSRVILSPmeglpGSDYTNANYCDGY--RKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWP
.  |  .|. |||| ... || .|| |         || ||.|       ..  ||||||||| |. |||.|| |. .| | |.|.  |   .|| .|||
nsgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywp

TRDQE--KYGFIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppDAGPIVVHCSAGVGRTGAYIVIDS
   ..  .  ...| | .   |  . .| | .|.. .   . |||.||| ||||| |  | |.. .|   . .    .||.|||||||.|||| ....| 
islkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh--ltgpmvvhcsagigrtgvflcvdv

MLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
..  | .. ...|   |. .| ||. ||||.||| | .. . |
vfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivle
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_4.PD 45-281 34 2e-50 163.3 In-house 21-261 (264) Show / Hide 
Range on Protein: 45-281
Range on HMM: 21-261/264
Sequence Identity: 34% (84 aa)

SNLETNKPKNRYANVIAYDHSRVILSPMEglPGSDYTNANYCDGYrKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQ
|  | |. |||||...  |..||.|   .  |  ||  |..      .  ||.||||| ||..||| ||........||. .|.| .  || .|.| ...
saseknsdknryadilcidetrvvlknrd--pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypekse

E--KYGFIQVTLLDTTEL--ATYTVRSFALVK-----NRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKScnPPDAGPIVVHCSAGVGRTGAYIV
.  |.|  ..||....|   |   ..|. ...     . . |.  || .|.. |.|.  |. |..|...  ||   ..  .||||||||||||| ... |
kvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvG

IDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
|    ||.    ...   |  ||| |   ||.. |..|.   | | 
idyatirirenseievldivrelramrlkavqshlqflfllvvlie
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_6.PD 48-281 33 1.7e-46 150.4 In-house 22-250 (253) Show / Hide 
Range on Protein: 48-281
Range on HMM: 22-250/253
Sequence Identity: 33% (77 aa)

ETNKPKNRYANVIAYDHSRVILSPMEGLpgsdYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTR--DQE
..| .|||.|.  .| .|. |.  | .    |  ||. .   |.. .| ||.|| .|. .||.|.  . .. |||. .| |.. |. .| . .  |. |.
lkfkdrnrytniqCcdagrlkladdedf----yihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdar

KYG-FIQVTLLDTTELATYTVRSFALVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppdaGPIVVHCSAGVGRTGAYIVIDSMLERIK
. . .|. .. ..    .|||   .   . |.  || ... .|||||||.  .| | ..| ||...||||||||||||||. ..| ..|| ... .  ..
kitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdk----kPivvhCsaGvGrtGtlaliliilealr

HEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEALYE
   .. || .|   |||| ||.. .  . |       
lpdfqgvkdllvklreerfravqtevqylyalrcvle
Phosphatase Spur_PTPRD2.AA Subfamily.R_Nematode_2.PD 44-278 27 4.7e-46 148.8 In-house 23-255 (261) Show / Hide 
Range on Protein: 44-278
Range on HMM: 23-255/261
Sequence Identity: 27% (66 aa)

HSNLETNKPKNRYANVIAYDHSRVILSpMEGLpGSDyTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRD
.|.   .| |.|| .|   ....|    ..|   ..   ||. .   ... .||||||| .|. ||| ||  .  ..|||...|... ||..|.|.. ..
esaaylpkdkhRypdvPCkpetavevi-vdgk-rvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfplet

QEK--YGFIQVTLLDTTELATYTVR--SFALVKNRS-MEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppdaGPIVVHCSAGVGRTGAYIVIDS
|   | .... ... ....  .   ..  ...   .. | |. .|.. |||.|||.  . .   ..||  .     |||||||||.|||.|.| .. . .
sqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkkse----kPivvhCsaGiGRtmafigtey

MLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEA
......|. .   .  || .|   .|||.|. ... .   
lareveadptieltealkelrehRwkgiqtesqlywltlg
Phosphatase Spur_PTPRD2.AA PTPc_motif 180-281 45 4.3e-45 157.04 SMART 1-92 (92) Show / Hide 
Range on Protein: 180-281
Range on HMM: 1-92/92
Sequence Identity: 45% (49 aa)

EVKQFQFTAWPDH-----GVPEHATSVLAFISRVKSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIF
.|.....|.||||     ||||   |.| || .|..       |||||||||.|||| ...||.|...      |||.. |  .| ||. ||||||||||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

IHEALYE
..... |
CYRCILE
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_5.PD 38-279 25 1.2e-36 118.0 In-house 13-253 (258) Show / Hide 
Range on Protein: 38-279
Range on HMM: 13-253/258
Sequence Identity: 25% (63 aa)

QQFTWDHSNLETNKPKNRYANVIAYDHSRVilspMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCdQ
.  . . .. | |. |||. .|  .|..||    . . . ..| ||.. .    .. .| || || .| .|||||| ... ...|.... || .. .. .
kpnketckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-s

YWPTR--DQEKYG--FIQVTLLDTTELA--TYTVRsfaLVKNRSMEKREVKQFQFTAWPDHGVPEHATSVLA-FISRVKSCNPPDAGPIVVHCSAGVGRT
..|..  |  ..|  ||...  .. |     |||    .. .   |.  .|  ..| |... ||.. .|..  | .| | .  .  |.||....|.||.|
ffpletgdylnlgkmfinnrkvevkedekkeytve---vlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRa

GAYIVIDSMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEEQYIFIHEAL
  .... . | ....|...|   .  .| ||  .|..  || ....|. 
gtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaav
Phosphatase Spur_PTPRD2.AA Subfamily.R_Nematode_3.PD 46-276 22 3.5e-36 116.6 In-house 19-259 (267) Show / Hide 
Range on Protein: 46-276
Range on HMM: 19-259/267
Sequence Identity: 22% (54 aa)

NLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDgYRKQNAYIATQGPL--------LETMADFWRMVWEQRTNTIVMMTKLEE---RNRVK
.|. .  ..|...|. . ..||.|        .|. .||.     ...  | ||.|.         .|.  || |. ..... .||. .  |   ..  |
slskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeek

CDQYWPTRDQEKYGFIQVTL----LDTTELATYTVRSFALvKNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppdaGPIVVHCSAGVGRT
| .|.|.  ...  | .|..     ..   .    |.. . .    ..  |.  ....|.....||....|. |  |....     |.|||||.|..|..
cseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsdGisRs

GAYIVIDSMLERIKHEK-TVDIYGHVTCLRAQRNYMVQTEEQYIFIH
.  .|.   . | ..| ..|.   .. ||.||   .|||....|.  
atlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvi
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_egg.PD 39-278 24 1.5e-28 91.7 In-house 15-251 (257) Show / Hide 
Range on Protein: 39-278
Range on HMM: 15-251/257
Sequence Identity: 24% (58 aa)

QFTWDHSNLETNKPKNRYANVIAYDHSRVILSPMEGLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRvkCDQY
. .  ..  . .. | |   |   . ||| |   .|    |.  ||. .|    | .| .| || .|. ||||||.... .|||.|   | .|  |. ||
eislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakeser--ceyy

WPTRDQEKYGF----IQVTLLDTTE--LATYTVRSFALVKNRsMEKREVKQFQFtawpDHGVPEHATSVLAFISRVKSCnppdAGPIVVHCSAGVGRTGA
|  ..|   .    .... |.  .     ..|  . ||     |.. .. .|     |.  | |  . ...      . |.||..  || .... . |. 
wpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd-deelflehwqg----dvnylsdvysplrvlrklrnl----skpvvvqdilGvskaat

YIVIDSMLERIKHEKT--VDIYGHVTCLRAQRNYMVQTEEQYIFIHEA
 | ..    .    .   |  || .|.. |..  .|.|..        
lvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrl
Phosphatase Spur_PTPRD2.AA Subfamily.N_Fungi_PTP1.PD 52-146 34 1.5e-24 78.3 In-house 47-155 (343) Show / Hide 
Range on Protein: 52-146
Range on HMM: 47-155/343
Sequence Identity: 34% (37 aa)

PKNRYANVIAYDHSRVILS----P----MEGLPGSDYTNANYCDGY---RKQN---AYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQ
|||| |.. |.||||.|     .       | ..|| ||||        ..|    |||||.|| .|. ||.... .   . |...|.. | |. ||..|
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr

YWPTRDQEK
|.  . .. 
YWqegsydd
Phosphatase Spur_PTPRD2.AA Subfamily.N_Fungi_PTP1.PD 176-279 35 5.1e-17 53.5 In-house 210-338 (343) Show / Hide 
Range on Protein: 176-279
Range on HMM: 210-338/343
Sequence Identity: 35% (44 aa)

MEKREVKQFQFTAWPDHGVPEHATSVLAFIS-------RV---KSCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLE------RI----KH----EKTVD-
|  || |.|.  |.| ..  .  |.|  .             .  .   . ||.||||||||||| .. .||.|.       ...     || | |   |
sepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDl

IYGHVTCLRAQRNYMVQTEEQYIFIHEAL
  || ||  |||. .|.|||.|||     
isiivnelrkqrismvqnldqfifiYeal
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_eak.PD 52-208 24 2.9e-15 48.0 In-house 28-182 (281) Show / Hide 
Range on Protein: 52-208
Range on HMM: 28-182/281
Sequence Identity: 24% (38 aa)

PKNRYANVIAYDHSRVILSPMEgLPGSDYTNANYCDGYRKQNAYIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTR-DQEKYGFI
.||  ... .|.  | |..   |    | ||   .     . || |  .  . .  ||.|| ||.. .||.. .  | .| |.|.| . .. |||...|.
nrnrvvkivpqdrylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlkyGil

QVTLLDT-TELATYTVRSFALVKnrSMEKREVKQFQFTAWPDHGVPEHaTSVLAFISRV
  .   . . . .| . | |    |  .|. ...  | .  .|      ||.   .   
dverkeyavkrniletrllilrk--GnethrvlhykvfGwtettlpky-edflalrkvm
Phosphatase Spur_PTPRD2.AA Family.DSP.PD 159-270 17 3.9e-11 34.5 In-house 148-242 (387) Show / Hide 
Range on Protein: 159-270
Range on HMM: 148-242/387
Sequence Identity: 17% (20 aa)

ElatytvrsfalvknrsmeKREVKQFQFtAWPDHGVPEHAT---SVLAFISRVKScnppDAGPIVVHCSAGVGRTGAYIVIDSMLE-RIKHEKTVDIYGH
.                  . ..|  .. ...||..|  .    ... ||. ...    . | ..||| ||.||.|  |..  |   ... |...|.  .
k------------------elgikylri-pidDhnapplenlfekaidfieegnd----skgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrs

VT--CLRAQRNYMVQTEE
   ... . ....| .. 
kRpgvitpnqgflkqlkd
Phosphatase Spur_PTPRD2.AA Subfamily.PTPDC1.PD 175-277 26 3.3e-09 28.2 In-house 129-222 (229) Show / Hide 
Range on Protein: 175-277
Range on HMM: 129-222/229
Sequence Identity: 26% (26 aa)

SMEKREVKQFQFtAWPDHGVPEhATSVLAFISRVKSCNppDAGPIVVHCSAGVGRTGAYIVIDSMlerikHEKTVDIYGHVTCLRAQRNYMVQTEEQYIF
.. ....  ..| ...|.||.   ...|  .  |..      | | ||| || ||||  |    .     . | ..    .. .|..|.|| ||  ...|
elmrqgiyfynf-glkDygvas-leriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylv-----yakrltaeeaiklvrskrpksiqtreqvel

IHE
   
vee
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_eak.PD 210-280 26 2.5e-08 25.2 In-house 206-277 (281) Show / Hide 
Range on Protein: 210-280
Range on HMM: 206-277/281
Sequence Identity: 26% (18 aa)

SCNPPDAGPIVvHCSAGVGRTGAYIVIDSMLERIKHEKT--VDIYGHVTCLRAQRNYMVQTEEQYIFIHEALY
||   ||.  .. |  |.|...||| ... |   |.    .   .   . .|.. | .. |. ||.|..    
ihtppsfapii-qsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivl
Phosphatase Spur_PTPRD2.AA Subfamily.PTEN.PD 152-254 24 2.5e-06 18.7 In-house 31-134 (305) Show / Hide 
Range on Protein: 152-254
Range on HMM: 31-134/305
Sequence Identity: 24% (26 aa)

VTLLDTTELATYTVRSFALVK--NRSMEKREVKQFQFTawpDHGVPEhATSVLAFISRVKSCNPPDAG-PIVVHCSAGVGRTGAYIVIDSMLERIKHEK-
. ||.|.  . . .| ..  .  . |  .  |... |.   ||  |.    .  ... |..    |    ..||| || ||||  |.   .. ||...  
lillltvykgkgklrilnargekedsdfdgrvavypfd---Dhnppt-leLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksad

-TVDIYGH
...||.. 
ealaiyde
Phosphatase Spur_PTPRD2.AA Subfamily.CDC14.PD 193-236 38 2.9e-06 18.8 In-house 180-218 (258) Show / Hide 
Range on Protein: 193-236
Range on HMM: 180-218/258
Sequence Identity: 38% (16 aa)

GVPEHATsVLAFISRVKSCnppdAGPIVVHCSAGVGRTGAYIVI
.||..|  .  |.. . ..     | |.||| ||.||||. |  
tvPsdai-lkkfleiteka----eGaiavhCkaGLGrtgtligc
Phosphatase Spur_PTPRD2.AA Subfamily.DSP19.PD 177-244 23 3.5e-06 18.6 In-house 44-106 (139) Show / Hide 
Range on Protein: 177-244
Range on HMM: 44-106/139
Sequence Identity: 23% (16 aa)

EKREVKQFQFTAWPDHGVPEHATSVLAFISRVKSCNppdaGPIVVHCSAGVGRTGAyIVIDSMLERIK
.. ..|. .    |.. . ..  ..| ||  ..| .    | ..|||.||| |. . .||  .... .
kdftyksieilDlpetkllsylkealdFieearskd----grvlvHCnAGvSRsas-vviaylmkdee
Phosphatase Spur_PTPRD2.AA Subfamily.DSP11.PD 173-251 25 6.2e-06 17.8 In-house 37-117 (141) Show / Hide 
Range on Protein: 173-251
Range on HMM: 37-117/141
Sequence Identity: 25% (21 aa)

NRSMEKREVKqFQFTAWPDHGVPEHATsVLAFISRVKSCN---PPDAGPIVVHCSAGVGRTGaYIVIDSMLERIKHE--KTVDI
........|| ..    | | |||. . |  |...||.       .   | |||  || ||| |..   ....   .  . .. 
kkeltdegvk-ykklncpGhevpeked-vkkfkeavkefleknkdndkligvhCthGvnrtG-yliCrylidvegyspedaiea
Phosphatase Spur_PTPRD2.AA PTPc 313-575 40 3.7e-136 459.54 SMART 1-308 (308) Show / Hide 
Range on Protein: 313-575
Range on HMM: 1-308/308
Sequence Identity: 40% (126 aa)

GMENEFKRLASQKAQPS--------RFVSANIPANK--FKNRLL-NIQPYEGNRVCLQPIRGV----EGSDYINASHIDGYRQRNAYIATQGPLAETTED
| ..||.|| ... ...        .. .|. |.|.   |||   .| .|. .||.|.|. |     ||||||||..||||.....||.||||| .| ||
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMLWEQNSTIIVMLSKLREM--------GREKCHQYWPAERSARYQYFVVDPMSEYNMP-QYILREFKVTDARD--------GQSRTIRQFQFTDWPE
|||| |.|...||||| .. |.        |||||||||| | .  |  . |  .||...|  |..|.|.||.  .        ...||......|.||.
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

QGVPKSGEGFIDFIGQVHKTKEQFGQ-----------------EGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQY
.|||.| ..|.||| ||.........                 .||| ||||||.||||.|...........    ||.||.|||.|.||| |||||.||
HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY

QFCYHAALEYLG
.|||...|||. 
IFCYRCILEYIK
Phosphatase Spur_PTPRD2.AA Y_phosphatase 339-572 50 1e-123 422.13 Pfam 1-243 (243) Show / Hide 
Range on Protein: 339-572
Range on HMM: 1-243/243
Sequence Identity: 50% (124 aa)

NKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDG-YRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGR-EK-CHQYWPA---ER
|| |||  .| .|. .||.||||.| |.||||||..||| |.. .|||.||||. .| |||||| |.|..|.|||| .. |||| || ||||||    ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

SARYQYFVVDPMSEYNMPQYILREFKVTDARD--GQSRTIRQFQFTDWPEQGVPKSG-EGFIDFIGQVHKTKEQFGQEG--PISVHCSAGVGRTGVFITL
. .|  | |  .||. .| |..|.|.||.  |  ...||......|.||..|||.|.  ...||| ||.| ..  .. |  || ||||||.||||.|...
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-NPDHGCPPIVVHCSAGCGRTGTFCAI

SVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
......|. ||.||.||.||..|.||| |||||.||.|||.. ||
DIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase Spur_PTPRD2.AA Subfamily.R_Anemone_2.PD 314-574 52 1.4e-112 367.3 In-house 2-261 (262) Show / Hide 
Range on Protein: 314-574
Range on HMM: 2-261/262
Sequence Identity: 52% (136 aa)

MENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
...|..||. ........ ||. |.||.|||  || .|.  || ||.. |.||||||||..|||||...||||||.||.|| ||||||.|||||..||||
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

SKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGqEGPISVH
....| |. |.|.||| . |  |.  ||. ..| .. .|.||.|||.  .  ..|..|||..|.||..|||.|| ...|...||.|.... | .||| ||
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesg-agpivvh

CSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
||||||||||||.....|||.. |..||.|||||.||.||..||||.|||.|.|.. ||.|
csaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase Spur_PTPRD2.AA Subfamily.RA.PD 314-574 50 4.2e-100 326.2 In-house 2-265 (266) Show / Hide 
Range on Protein: 314-574
Range on HMM: 2-265/266
Sequence Identity: 50% (134 aa)

MENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
.|.|||.|.| | | ...  || ..|| |||...| ||. .|| |. ..|.| |||||||.|||||... .||.|||..|| ||||||.|||.|. ||||
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

SKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVT----DARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEgP
..|.| ..|||.|||| | .  |    |    |  . .| .|.| ||     .|. .|| .||| || ||| ||| .| | .... .|.|...| ..  |
telkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh-p

ISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
| ||||||||||| ||.|. ||||.. |...|.|..|| ||.||| ||||. ||.|.|.. |||.
ivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi
Phosphatase Spur_PTPRD2.AA Subfamily.R_Sponge_2.PD 325-574 43 3.1e-91 297.2 In-house 11-261 (262) Show / Hide 
Range on Protein: 325-574
Range on HMM: 11-261/262
Sequence Identity: 43% (110 aa)

KAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPiRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKC
| .   .  |. . |. |||  .| ||. .|| |..  |...|||||||..|||..|.||||||||| || ||||||.||.....||||..|.| |.|||
ketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekc

HQYWPAE--RSARYQYFVVDPMSEYNMPQYILREFKVTDARD-GQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGqEGPISVHCSAGVGRT
..||| .   ...| .|.|   .| ....||.|..|.....  .......||.|. |||..|||.   ....| .|...... | ...|.|.||.|||||
akYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksg-nkaitvvCsdgvgrt

GVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
| ||.| .||||.. |. .|.|...| |||.|. .||...||.|...|.|||.
GtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi
Phosphatase Spur_PTPRD2.AA Subfamily.R_Anemone_1.PD 314-574 39 3e-87 284.2 In-house 2-257 (258) Show / Hide 
Range on Protein: 314-574
Range on HMM: 2-257/258
Sequence Identity: 39% (103 aa)

MENEFKRLASQKAQpsRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
...||.|| ..|..  .  .|. ..|| |||  .| ...  || |.   . | |||||||.........|.||||.|| ||.||||||.|......||||
yaaefqrlkeikee--ekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmL

SKLREMGREKCHQYWPAeRSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTkeQFGQEGPISVH
  | |.  .|||||||  ....|  . |  ... .. .||.|..... ..  ..|...|..|| ||..|||.     ...  .|.|.  .  .. |. ||
tnliegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks--slagarpvvvh

CSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|||||||||.|. .. .||... | .||.|..||..|..|| ||||..|| |...| ||.|
CsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal
Phosphatase Spur_PTPRD2.AA Subfamily.RB.PD 318-573 41 9.9e-87 282.3 In-house 6-259 (261) Show / Hide 
Range on Protein: 318-573
Range on HMM: 6-259/261
Sequence Identity: 41% (107 aa)

FKRLASQKAqPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLR
...|.. .   .  ..|. ..|. |||  ||.||. .|| |. ..  ...|||||..|.||.... |||||||| ||..|||||.||..|.||||| .| 
yeelkkvgk-dqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlv

EMGREKCHQYWPAER-SARYQYFVVDPMSEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHCSA
| |.|||..||||.. .  |    |. ..| .. ....||||..   . ..|..||..|| ||. |||.. .  .||. .|... |....|| |||||||
EkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsa

GVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||||.||.|  .|.... . .||.| .|  ||..|  .||||.|| | ... |..  
GvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl
Phosphatase Spur_PTPRD2.AA Subfamily.RG.PD 314-572 40 2.1e-86 281.3 In-house 2-261 (264) Show / Hide 
Range on Protein: 314-572
Range on HMM: 2-261/264
Sequence Identity: 40% (106 aa)

MENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
.|..|. . . |..  .  |.. . || ||| .|| ..|  || |.|. |..|.||||||.|||||. ..||.|||||.||.||||||.||.|..|||||
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

SKLREMGREKCHQYWPA-ERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRT--IRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQfgQEGPI
..| | ||.....|||. . . ... . |  .|. .. .|..|.| . . .| ....  .||...|.||..|.|.|   .. |. ......  . ||| |
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaanke--eaGPi

SVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
|.||||||.|..| |. .|.....| .|...|..|..|..|| .|.||.||.| |.| ||  
vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle
Phosphatase Spur_PTPRD2.AA Subfamily.RK.PD 314-574 41 4.4e-86 280.0 In-house 2-266 (267) Show / Hide 
Range on Protein: 314-574
Range on HMM: 2-266/267
Sequence Identity: 41% (110 aa)

MENEFKRL--ASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVeGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
. .||. |   . . |   . .|  . |. |||  .| .|.  .| |... |   ||||||. ||.|.. .|.|.||||| ||..||||.....|.. ||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MLSKL-REMGREKCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTD-AR-DGQSRTIRQFQFTDWPEQ-GVPKSGEGFIDFIGQVHKTKEQfGQE
||..|  | || || .||| . . ||. . |  ..     ... | |.|.  ||   . |..|||||. |||  .||.| ......|.|.|..|. ..||
mlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-eee

GPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
.| |||.|| ||.|.||....||| .. ||.||.|..|| ||.... ||.||.||.|.| ..||.| 
GrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal
Phosphatase Spur_PTPRD2.AA Subfamily.N9.PD 314-573 40 2.2e-84 274.9 In-house 2-273 (275) Show / Hide 
Range on Protein: 314-573
Range on HMM: 2-273/275
Sequence Identity: 40% (110 aa)

MENEFKRLASQkAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
. .|.. . .. .   .|  ....||  |||  ..  |.  || |. . . | ||||||...|||.|..|.||||||| .|..|||||.|||..||| ..
lskeyadirne-pveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmt

SKLREMGREKCHQYWPA--ERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFG------
. |.|| || ||||   | ||..  . |  ..  .. .|  | ..........||..  |||. ||. |||.|.. ..|.. .| ... ..         
trvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde

-----QEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
   .. || ||||||.|||| |||| . |.|.. .| ||...|||.|||||  ..||..||.||| | |||  
skghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
Phosphatase Spur_PTPRD2.AA Subfamily.R_Ecdysozoa.PD 314-573 39 2.3e-84 274.4 In-house 2-267 (269) Show / Hide 
Range on Protein: 314-573
Range on HMM: 2-267/269
Sequence Identity: 39% (105 aa)

MENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
.|.|...| ..   .   . ..   |..|||  .|.... .|| |..| | | |||||||.| ||.... .|| |.|. .| .|||||..||..|.||||
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

SKLREMGREkCHQYWPAERSARYQYFVVDPMSEYNMPQYILREFKVTDAR---DGQSRTIRQFQFTDWP-EQGVPKSGEGFIDFIGQVHKT---KEQFGQ
|.| |. |. |..||| |   .|.  .|...|| ....|| ||..|.        .|| . |...| |... ||.. .| ...| ||..    ... | .
snlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgs

EGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
.|| |||||||||.|.|..|...|.... |  ||.|.||| || ||. .||  .||.|.|.| ..| 
rsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady
Phosphatase Spur_PTPRD2.AA Subfamily.N12.PD 329-573 40 3.8e-78 254.0 In-house 22-268 (270) Show / Hide 
Range on Protein: 329-573
Range on HMM: 22-268/270
Sequence Identity: 40% (101 aa)

SRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYW
.  ... . |. |||  .| ||. .|| |. |...||||||||..| | ... .|||.||||..| .|||||.||.| .|.||. .. |.|.||..||| 
ysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryW

PAE--RSARYQYFVVDPMSEYNMP-QYILREFKVTDArdGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPISVHCSAGVGRTGVFI
|  .. ... | |. ..| ..  ....| .||.    ..||...||..|.||..|||.| .  ...| .|....|   .. |.|||||||||||. |.. 
peegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaGvGrtGtii

TLSVVLERMRYEGI---VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
 | | .. | |   .|.|. |  ||.||.|.|||..||.. |.| .|.   
aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
Phosphatase Spur_PTPRD2.AA Subfamily.N_Choan_1.PD 313-574 35 4.5e-75 244.1 In-house 1-261 (262) Show / Hide 
Range on Protein: 313-574
Range on HMM: 1-261/262
Sequence Identity: 35% (95 aa)

GMENEFKRLAS-QKAQPSrfVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIV
|. .|.. ||. .. ...  .... ..|. |||  ||  |.  || ..|    . .|||||....||.. ..|||||||. .. ..||.|.|||. ..||
Gfieeyeklaeigvdnta--taskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaiv

MLSKLREMGREKCHQYWPAER-SARYQYFVVDPMSEYNMPQYILREFKVtDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQeGPI
|. .  | |. |||.||| |. . ..  ..|  .|| . ..|| |.||. ....|..|...|...| ||..|||.. . ...|  .|.|....  .  |.
mvtreieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-apl

SVHCSAGVGRTGVFITLSVVLERMRYEGIV-DMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
 .||||||||||..|.|  ...... .  . |. ..|. || .|  ||||  ||.| |.||..| 
vihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal
Phosphatase Spur_PTPRD2.AA Subfamily.N3.PD 330-570 42 3.1e-73 237.9 In-house 17-256 (261) Show / Hide 
Range on Protein: 330-570
Range on HMM: 17-256/261
Sequence Identity: 42% (103 aa)

RFVSANIPANKFKNRLLNIQPYEGNRVCLQpirGVEGsDYINASHI----DGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCH
|. |.|  |||  .| ||.  || |.     |  |||||...    ..  . | |||||||||.|..|||.|.|||.||.||||  | ||| ||||||| 
aisaarkpenlaknryrdilpydatrvklk---eset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkCh

QYWPAE-RSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPISVHCSAGVGRTGVF
.  . ..  | |   .| .  .|.|||. ..|..  ..|.| |.|...||..|||.. . |..|. .|.|...  |.| |. ||||||.|||||.|.| .
qyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrs--gkeePvvvhCsaGigrtGvl

ITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAA
 |  .  .  | . . |...| || ..|||..||.|  .|      
illetalalieaaepvypldivrtmrdqramlvqtvsqykfvCeai
Phosphatase Spur_PTPRD2.AA Subfamily.N13.PD 315-574 38 2.5e-70 228.6 In-house 3-258 (259) Show / Hide 
Range on Protein: 315-574
Range on HMM: 3-258/259
Sequence Identity: 38% (102 aa)

ENEFKRLASQKAQPSRFvSANIPANKFKNRLLNIQPYEGNRVCLQpirgVEGSdYINASHIDGY--RQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVM
..||| |   |.. .   ...  .|| |||  |. ||.  || |.     ||. |||||.|      ..  |||.|||| ||..|||.|.|||....|.|
aeefkelrelkpldtce-vgkkkenkdknryrnvlPydetrvklg----degg-yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviam

LSKLREMGREKCHQYWPAERSAR---YQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgQEGP
... .| |. |||.||| ... .   .. . |. .   .. .. .|...|.| . |.|| . ...|..||. |||.| . .. |..|.. ..   ..|||
vtlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt---dagP

ISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
 ||||||.||.||.||. |||. .  .  .|. ..|. || || ..|||.||| |.|.|.|| | 
ivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
Phosphatase Spur_PTPRD2.AA Subfamily.N5_RR.PD 334-574 35 5.1e-70 227.5 In-house 18-264 (265) Show / Hide 
Range on Protein: 334-574
Range on HMM: 18-264/265
Sequence Identity: 35% (87 aa)

ANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEG-SDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAE
... .. |||  .| | |  ||.|..  . .  |.|||| .| ||..  .||.||||||..| .|||||........|||| ||.|. |.||..|.| ..
levfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPda

RSA----RYQYFVVDPMSEYNMPQYILREFKVTDARDgQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQE-GPISVHCSAGVGRTGVFIT
..    ||. . .   .  .  .| .|.. .. ...  .|..  . .||||.. .|.. . ..|.. .|....|.  .. .|. ||||||.||||.||. 
edyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfia

LSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
|. . ..| |..||....|  || .|  ||||..||.. ..|  .|| 
isiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl
Phosphatase Spur_PTPRD2.AA Subfamily.RC.PD 314-573 37 4.4e-68 221.3 In-house 2-286 (288) Show / Hide 
Range on Protein: 314-573
Range on HMM: 2-286/288
Sequence Identity: 37% (107 aa)

MENEFKRLASQKAQPSRfVSANIPANKFKNRLLNIQPYEGNRVCL-------------------QPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAET
.| ||.|| | ... .    |. . || |||  .. ||. ||| |                   . | . |||.|||||.||.|.. . |||.|||| ||
leaefqrlpsvrskrti-kiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplket

TEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWpAERSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFI
 .|||||..|.  ..||||..|.|  |||| .||  |    |   .||   . . ..|||| ... . .. .||.. |.|.|.|.....|.  . ....|
vddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkli

GQVHK------TKEQF--GQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
  |..      . | |   . .|. |||..|..|||.||.|  .|| .  |  ||.|| || || .|| ||..|.||.. |..  |.
qvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet
Phosphatase Spur_PTPRD2.AA Subfamily.N14.PD 317-574 34 7.2e-67 217.1 In-house 5-274 (275) Show / Hide 
Range on Protein: 317-574
Range on HMM: 5-274/275
Sequence Identity: 34% (93 aa)

EFKRLASQKAqPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVeGSDYINASHIDGY--RQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLS
|. |.. ...  . . .|..| |. |||  .. ||| ||| |.| .    ..|||||.|      ..  ||..|||| .| .|||.|.|||...||||..
eyeripkkre-dallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

KLREMGREKCHQYWPAE----RSARYQYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQE---
 .| |.||...|.| .    ...... | |      . ...| . .|.     .. ||.  .|.||||..|||.  .||..|. .|.  .... .|    
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseves

-----GPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
     |. |||||||||||| |.  .... .  .  .|. .....||.||  .|||  ||.| |.. ..|| 
vkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl
Phosphatase Spur_PTPRD2.AA Subfamily.N_Choan_2.PD 318-573 33 1.4e-66 216.1 In-house 2-264 (266) Show / Hide 
Range on Protein: 318-573
Range on HMM: 2-264/266
Sequence Identity: 33% (89 aa)

FKRLASQKAQPSRFVsaNIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKL
||||  |. . ..    ..  ||  ||  .| |    ||.|....  . . |||| .. |. . ...|||..|||. |...||||.||...| |||...|
fkrldkqevseeaiP--eyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgl

REMGREKCHQYWPAERSARYQY----FVVDPMSEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKSGE------GFIDFIGQVHKTKEQFGQ
 | ||.|| .|||||.  . ..      |  .|| ..  |||.. ...   .|..|... |....||..|||...        .. . .|....... ..
eEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldk

EGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
.|. |||||||||||..|..  ... .  .. ||. . .. || .|.|.||. .||.. |.| .|| 
aePllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey
Phosphatase Spur_PTPRD2.AA Subfamily.RN.PD 314-571 42 8.1e-65 210.4 In-house 2-260 (264) Show / Hide 
Range on Protein: 314-571
Range on HMM: 2-260/264
Sequence Identity: 42% (109 aa)

MENEFKRLASQKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQR-NAYIATQGPLAETTEDFWRMLWEQNSTIIVM
.|.|.. |.. .|.||    |. . |  |||  .. ||. .|| |.     | ||||||| |     |  |||||||||..|  |||.|.|||...||.|
lekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivn

LSKLREMGREKCHQYWPAERSARYQYFVVDPMSEYNM-PQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfGQEGPIS
..|.| | ..|..||| | |. |. . |. .||.    .|..| | . . .  ..||. || |  |||.||| |   ...|  .| |.    |.  || |
ltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyr--Grscpiv

VHCSAGVGRTGVFITLSVVLERMRyEGI--VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAAL
|||.|.|||||.| . .||||.   |.  .|.  |.. || ||| .|.|.||..|.. |   
vhcsdGaGrtGvyilidlvlerll-kGvkeidiaatlehlrdqrpglvktkdqfefaltava
Phosphatase Spur_PTPRD2.AA Subfamily.N23.PD 353-573 37 6.1e-61 198.1 In-house 116-348 (350) Show / Hide 
Range on Protein: 353-573
Range on HMM: 116-348/350
Sequence Identity: 37% (84 aa)

GNRVCLQ-PIRGVEGSDYINASHIDGYRQ-RNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSA--RYQYFVVDPMSEYN
|||.||   .  . .|||||...         .||||||.|.|  ||| |.||| | .|||| |  |... ||.||||... .   .. . ||. . ...
pnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrs

MPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTK-----EQF--GQEGPISVHCSAGVGRTGVF-ITLSVVLERMRYEGIV
| | ....     . |.. ....| |.| ||||| | ...|.|.|...       .     . || .||||||||||.| .|.. |    .||... . |
segwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngii

DMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
. || ||  |||........|.| ||.      
niprvvrrlrqqRkymvqkkvilkklyeavlea
Phosphatase Spur_PTPRD2.AA Subfamily.N20.PD 324-574 41 3.6e-57 185.6 In-house 11-256 (257) Show / Hide 
Range on Protein: 324-574
Range on HMM: 11-256/257
Sequence Identity: 41% (104 aa)

QKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQpirgvEGSDYINASHIDGY--RQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGR
|  |  | | | |.|. |||  .| ||.  || |      .  ||||||.|      .   ||||||||  | .|||.|. |.|| .| |...  | |  
lknlpgefnsgnqpsnreknryrdilpydstrvplg-----kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggi

EKCHQYWPAE--RSARYQYFVVDpMSEYNMPQY-ILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqfgQEGPISVHCSAGV
||..|||    .    ..| |  . .|.. || |.| |.| .   | |....|.||| ||..| | | . || .|   .|..||. ||||||.||||||.
ikcyhywpislkkplelkhfrvf-lenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh----ltgpmvvhcsagi

GRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
 . ||.  .  .  ..... |  .| ||  ||||..||.|||   || |       
grtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl
Phosphatase Spur_PTPRD2.AA Subfamily.N1.PD 331-572 34 4.9e-55 178.5 In-house 20-265 (268) Show / Hide 
Range on Protein: 331-572
Range on HMM: 20-265/268
Sequence Identity: 34% (86 aa)

FVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGvegsDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPA
.|. |.|. .||  ...||.  |. |.        |||||| ..  . .  || |||||..|.. ||.| |||||  ..|| |. | .. ||.|||| |.
treaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpq

ERSA---RYQY--FVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFI
..    ..   . |  .|| .  ....| ....| .. ..|.| .|..| ||. |||.|   |..|. .|...     . ||. .|||||.||.| .  .
eeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtls

TLSVVLERMRYEGI---VDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
. .| ..  .|    ||. . .  || .|  ..|| || .| | | ||  
lvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_1.PD 315-574 29 4e-48 155.7 In-house 3-264 (265) Show / Hide 
Range on Protein: 315-574
Range on HMM: 3-264/265
Sequence Identity: 29% (79 aa)

ENEFKRLASQKAQPsRFVSANIPANKFKNRLLNIQPYEGNRVCLQpiRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLS
.||. |.  . .  .  . .   .. |||  ...  . ||| |.  ..   |||| | ..    . . .| .|.|| .|..||| |.  ..   |||| |
rdefralkkfndee-kvkafkeaqeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlc

KLREMGREKCHQYWPAERSARYQY------FVVDPMSEYNMP---QYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqf
| |.|. ||..|.||..  . ..       .|. ......    . .... ...    | ..|.....|.||||..|||.   . .... .|.. |    
kliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk---

gqeGPISVHCSAGVGRTGVFITLSVVLERMRY-EGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
  ||| ||||||.||||  .... .|...   . | || . || .| ||.||. || | ..  |.|.    
---gPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf
Phosphatase Spur_PTPRD2.AA PTPc_motif 469-572 43 1.1e-46 162.34 SMART 1-92 (92) Show / Hide 
Range on Protein: 469-572
Range on HMM: 1-92/92
Sequence Identity: 43% (47 aa)

TIRQFQFTDWPEQ-----GVPKSGEGFIDFIGQVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQY
|......|.||..     |||.  .....|| .|.|         || ||||||.||||.|.........      ||.|||||..|.||| |||||.||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY

QFCYHAALE
.|||.. ||
IFCYRCILE
Phosphatase Spur_PTPRD2.AA Subfamily.R_Nematode_2.PD 367-574 32 4.5e-44 142.3 In-house 55-260 (261) Show / Hide 
Range on Protein: 367-574
Range on HMM: 55-260/261
Sequence Identity: 32% (69 aa)

SDyINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERSARY--QYFVVDPMSEYNMP-Q-YILREFKVTDA
.. | | ...   . . .||||||| .|.|||| |.  ..   ||||..  |  .|||..|.| | | .   . | .  .|. ..  .    | .||.|.
vp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkveds

RD-GQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgqegPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTED
    ..||.. .|...||..|||||     . .  |.| ..      || ||||||.|||. ||.  .. ...  .  . . ...| || .|.  .||| 
tgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek------PivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtes

QYQFCYHAALEYL
|. .   .|| .|
qlywltlgalyrl
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_4.PD 324-573 31 3.9e-43 139.4 In-house 11-262 (264) Show / Hide 
Range on Protein: 324-573
Range on HMM: 11-262/264
Sequence Identity: 31% (80 aa)

QKAQPSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRgvEGSDYINASHIDGYrQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREK
.. .|.  .   . .|. |||  .|   . .|| |.        ||| || .     .  ||.||||| || .||| |.......||| .| | | ||| 
kgkappnvtasaseknsdknryadilcidetrvvlknrd--pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvek

CHQYWPAERSA-----RYQYFVVDPMSEyNMPQYILREFKVTDAR---DGQS--RTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqfgQEGPISVH
.|.| .        .|.  .|. . |  . . ||. .|||      |  |    .. .|.. |..||.     |...  |.| |    .|.|| ||||||
caryypeksekvvkfGkyritlvekkee-viadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkk----kekPivvh

CSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
||||  .. .     |.|  . ... . |. ||. |   ||.. |. |.   .|.     
csaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvliel
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_6.PD 334-574 29 8.3e-37 118.7 In-house 19-252 (253) Show / Hide 
Range on Protein: 334-574
Range on HMM: 19-252/253
Sequence Identity: 29% (72 aa)

ANIPANKFKNRLLNIQPYEGNRVCLQPirgvEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERS
. ..| .||  ||| ..  |. |.     .   || |. ..   . . .| ||.|| .| |.||.|.  . .. |||| .|| |.||. .| . .     
taflkfkdrnrytniqCcdagrlklad----dedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvG

--ARY-QYFVVDPMSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgqegPISVHCSAGVGRTGVFITLSVV
.. ..  |  ... .. . . |  |.     ...  .. ... .||. ||| |    . ..  |.|.|       || ||||||||||| .. . ..|| 
darkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk------PivvhCsaGvGrtGtlalilii

LERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
.|     .. . .  || .|   |||| || . ..  ||||   
lealrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_5.PD 314-574 26 1e-36 118.2 In-house 2-257 (258) Show / Hide 
Range on Protein: 314-574
Range on HMM: 2-257/258
Sequence Identity: 26% (70 aa)

MENEFKRLASQKAQPSrfVSANIPANKFKNRLLNIQPYEGNRVclqpIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVML
...||. ||| |..     . .  .|. |||  ... .. .||    ... | ..|||||.|.    .. .| || || .|.||||||  ... | .|.|
lktefeklaslkpnke--tckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvll

SKLREMGREKChQYWPAER--SARYQYFVVD-PMSEYNMPQYilREFK--VTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDfIGQVHKTKEQFGQEG
 .  |. . .. ...| |      .. ...     | .  ..   |..  |    ...|  ..  ..||... ||.. .  |  .   . .... |.. |
vedeelketav-sffpletgdylnlgkmfinnrkvevkedek--keytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik-raiekvlskkqgkna

PISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEYL
. |....|.||.| |..|||. | .  .  ... ...|..|.||| .|...|| . | |.|.|.  
pvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldyi
Phosphatase Spur_PTPRD2.AA Subfamily.R_Nematode_3.PD 338-572 22 8.1e-32 102.3 In-house 22-264 (267) Show / Hide 
Range on Protein: 338-572
Range on HMM: 22-264/267
Sequence Identity: 22% (56 aa)

ANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDgYRQRNAYIATQGPL--------AETTEDFWRMLWEQNSTIIVMLSKLRE---MGREKCHQ
..  ..|  ... .| .|| |.       .|.|.|. .    . .  | ||.|.        ..| | || |  .......|||.  |    . ||| .|
kkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcse

YWPAERSA--RYQYFVVDP--MSEYNMPQYILREFKVtDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEqfgqegPISVHCSAGVGRTG
.| .     . . . |    ...    .   |...|    ...  |..  ....|.|...|.. . ... |  |.| |       |. ||||.|..|...
Yypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfvekskt------pvvVHCsdGisRsa

VFITLSVVLERMRYE-GIVDMFQTVKMLRTQRPAMVQTEDQYQFCYHAALE
.    .. . .  . | .|. . .| || ||.  .||| .. |     |. 
tlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilk
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_egg.PD 313-573 22 1.4e-26 85.2 In-house 1-255 (257) Show / Hide 
Range on Protein: 313-573
Range on HMM: 1-255/257
Sequence Identity: 22% (61 aa)

GMENEFKRLASQKAQpSRFVSANIPANKFKNRLLNIQPYEGNRVCLQPIRGVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVM
..|..|..|     .   .  |    .. | |   ..  |  || |.  ||    |.| | ...|    | .| .| || .|||||||.....   ||||
elerrfeilersvde-islttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivm

LSKLREMgrEKCHQYWPAERSARYQY----FVVDPMSEYNMPQYIlreFKVTDARD-GQSrtiRQFQFTDWPEQGVPKSGEGFIDFigQVHKTKEQFGQe
.  .|   |.|. |||   |   ..    . .. .  .. .. .   |.||  .  |     .. .| .  .  | .... .  .  .| .   .  .  
ltsakes--erceyywpkaeseslvtvpGslrienlkvdskadpl---frvtklklvGgd---deelflehwqgdvnylsdvyspl--rvlrklrnlsk-

gPISVHCSAGVGRTGVFITLSVVLERMRYEGIV--DMFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
|. |..  || ........ . | ..    |.   . ..|..||.|.  |..  .| | |   | .  
-pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff
Phosphatase Spur_PTPRD2.AA Subfamily.N_Fungi_PTP1.PD 341-430 33 3.7e-23 73.7 In-house 47-150 (343) Show / Hide 
Range on Protein: 341-430
Range on HMM: 47-150/343
Sequence Identity: 33% (34 aa)

FKNRLLNIQPYEGNRVCLQ----P----IRGVEGSDYINASHIDGY----RQRNA--YIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQ
|||  || ||| .|| |.    .       ....|||||...       ..     |||||.|| .| .||.... . . ..|..|... |...|||..|
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr

YWPA
|.  
YWqe
Phosphatase Spur_PTPRD2.AA Subfamily.N_Fungi_PTP1.PD 461-573 31 2.3e-18 57.9 In-house 206-341 (343) Show / Hide 
Range on Protein: 461-573
Range on HMM: 206-341/343
Sequence Identity: 31% (37 aa)

DARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIG--------QVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLE-RMR-------------YEG
.|  ..  .. |.|.  |.. ..    | ..  .          . ..  .  .  || |||||||||||...||  .|.  .. | ....|. || || 
taavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaak

IVD-MFQTVKMLRTQRPAMVQTEDQYQFCYHAALEY
 |||. ||. |.|.|.| |                 
trDlisiivnelrkqrismvqnldqfifiYeallfy
Phosphatase Spur_PTPRD2.AA Subfamily.N_Nematode_eak.PD 339-493 25 2.5e-15 48.2 In-house 26-178 (281) Show / Hide 
Range on Protein: 339-493
Range on HMM: 26-178/281
Sequence Identity: 25% (40 aa)

NKFKNRLLNIQPYEGNRVCLQPIRgVEGSDYINASHIDGYRQRNAYIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWPAERsARYQY
.  .||...| |.. . | | . .  .   ||||| ..     . || |  .  .    ||.|. ||.|  ||.| .  |..||  .|.| .    ..| 
avnrnrvvkivpqdrylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdkt-evlky

FVVDP-MSEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSgEGFIDF
..|    || . . ||.  ..   .  ..  .  ...  | |  .||  | |. . 
GildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpky-edflal
Phosphatase Spur_PTPRD2.AA Subfamily.PTPDC1.PD 502-568 34 3.5e-11 34.7 In-house 161-222 (229) Show / Hide 
Range on Protein: 502-568
Range on HMM: 161-222/229
Sequence Identity: 34% (23 aa)

EQFGQEGPISVHCSAGVGRTGVFITLSVVlermrYEGIVDMFQTVKMLRTQRPAMVQTEDQYQFCYH
..  .|| |.||| || ||||| |.  .|     |   ..  . .|..| .||  .|| .| ... .
dfaleegkiavHCHAGlGRtGvliacylv-----yakrltaeeaiklvrskrpksiqtreqvelvee
Phosphatase Spur_PTPRD2.AA Family.DSP.PD 477-565 21 4.1e-09 27.9 In-house 158-238 (387) Show / Hide 
Range on Protein: 477-565
Range on HMM: 158-238/387
Sequence Identity: 21% (19 aa)

DWPEQGVPKSGE---GFIDFIGQVHKtkeqfgQEGPISVHCSAGVGRTGVFITLSVVLE-RMRYEgivdmfQTVKMLRTQRPAMVQTEDQYQF
..  ..|.  .    .|||| ....      ..| . ||| ||.||.|. |    .   .. .|      ......| .|| ... ....   
pidDhnapplenlfekaidfieegnd------skgvVlVHCkaGkgRsgtliiaYlmksegltle------ealdwvrskRpgvitpnqgflk
Phosphatase Spur_PTPRD2.AA Subfamily.PRL.PD 496-545 30 4e-08 24.9 In-house 70-119 (140) Show / Hide 
Range on Protein: 496-545
Range on HMM: 70-119/140
Sequence Identity: 30% (15 aa)

QVHKTKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERMRYEGIVDMFQT
.. |.| .  ..  ..||| ||.||. |...|... . |.||  |.. ..
ellkekfkeepkstvavhcvaGlGraPvlvalalieaGmkyedavefire
Phosphatase Spur_PTPRD2.AA Subfamily.CDC14.PD 507-567 34 1.2e-07 23.3 In-house 198-252 (258) Show / Hide 
Range on Protein: 507-567
Range on HMM: 198-252/258
Sequence Identity: 34% (21 aa)

EGPISVHCSAGVGRTGVFITLSVvLERMRYegivDMFQTVKMLRTQRPAMVQTEdQYQFCY
|| | ||| ||.||||..|.  . . . |.       .|.  ||  || .| .  | ....
eGaiavhCkaGLGrtgtligcyl-ikhyrf----taaetiawlriarPGsvigp-qqtylv
Phosphatase Spur_PTPRD2.AA Subfamily.DSP23.PD 500-565 26 2.9e-07 22.3 In-house 59-119 (128) Show / Hide 
Range on Protein: 500-565
Range on HMM: 59-119/128
Sequence Identity: 26% (17 aa)

TKEQFGQEGPISVHCSAGVGRTGVFITLSVVLERmryeGIvDMFQTVKMLRTQRPAMVQTEDQYQF
.|   .|....|||  |.|||| ...  .| |.    |.    ...  .| .|.  ..| .| .  
veeaekkeeavgvhcalGlGrtGtllacylvkee----gl-aaddaiaevrkrrkGsietveqeka
Phosphatase Spur_PTPRD2.AA Subfamily.DSP19.PD 470-555 19 2.9e-06 18.9 In-house 48-122 (139) Show / Hide 
Range on Protein: 470-555
Range on HMM: 48-122/139
Sequence Identity: 19% (17 aa)

IRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKeqfgqeGPISVHCSAGVGRTGVfITLSVVLERMRyegiVDMFQTVKMLRTQRPA
. . .  | ||. . .  .  .||| ......      | . |||.||| |.   . .. .... .    ... ......|..||.
yksieilDlpetkllsylkealdFieearskd------grvlvHCnAGvSRsas-vviaylmkdee----lslekalekvrearpc
Phosphatase Spur_PTPRD2.AA Subfamily.DSP12.PD 459-526 22 6.4e-06 18.0 In-house 39-100 (143) Show / Hide 
Range on Protein: 459-526
Range on HMM: 39-100/143
Sequence Identity: 22% (15 aa)

VTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKtkeqfgQEGPISVHCSAGVGRTGVFIT
... .. .. . .. | .| ||. . .  .  ..|| .  .      .|| . ||| ||| |   ...
lpelqkekgvkskliqilDepeedlLshldeavrFieegle------kegavlvHClagvSRSvtivi
Sequence
Name Sequence Type Origin Length Description Download
Spur_PTPRD2.AA Protein None 581 None Fasta, JSON
Spur_PTPRD2.NA RNA None 1743 None Fasta, JSON
Spur_PTPRD2.AA.PD2_313-575 Protein Phosphatase Domain None 263 None Fasta, JSON
Spur_PTPRD2.AA.PD1_26-284 Protein Phosphatase Domain None 259 None Fasta, JSON