spur_CDC14
Species: S.purpuratus
Alias: spur_CDC14
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: CDC14
Protein domain

Protein domains of spur_CDC14.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase spur_CDC14.AA Subfamily.CDC14.PD 78-329 55 1e-105 344.5 In-house 7-258 (258) Show / Hide
Range on Protein: 78-329
Range on HMM: 7-258/258
Sequence Identity: 55% (140 aa)

KKIVHYTSFDSKKRTNAACLIGCYAVRYFHQTPNSSEISIYFVTADNLSIKDASFGACTYNLTLLDCLKGIDKAVTHGFLDFENFDVEEYEHYERVENGD
..|   |. | . |.|||.||| .||  .  | . .  ..  .      ..|||.    |.| .   . |  .|.  ||.|   ||.. |.|.|||||||
qriyfctgtdmqvrsnaaaliglfavwclnmtdeqaiacldtakppfapfrdasyapvlyklhvryvisgayqallngfidvhtfdldtydhfervengd

FNWIVPNKYLAFSGPHPKSKIENGYPYHAPEAYFPYFRKHNITSIVRLNKKIYDARRFTDAGFDHYDLFFIDGSTPSDSILQKFLAISESSEGSLAVHCK
|  |.|||..|..|||.|||.|.||...|||... ||||.|.|.|||||||.|||..||||||.|.|||||||..|||.||.||| |.|..||..|||||
fttiipnkfialagphnkskvedGytllaPeklleyfrknnvttivrLnkklYdakkftdaGfahlDlffiDGtvPsdailkkfleitekaeGaiavhCk

AGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPGSVIGPQQHYMEEKQAAM
|||||||||||||..||.||||||.|||.||.||||||||||.|..||||..
aGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtylvekqadl

Phosphatase spur_CDC14.AA Family.DSP.PD 79-327 30 1.4e-50 164.2 In-house 8-242 (387) Show / Hide
Range on Protein: 79-327
Range on HMM: 8-242/387
Sequence Identity: 30% (77 aa)

KIVHYTSFDSKKRTNAACLIGCYAVRYFHQTPNSSEISIYFVTADNLSIKDASFGACTYNLTLLDCLKGIDKAVTHGFLDFENFDVEEYEHYERVENGDF
.|   |  | . |.||| ||| .||    .| .   . .  |  ...  .||| .  ...|      .|   | ..||.|. .||...|.|.||||||..
riyfctGtdmqvrsnaaaliGlfavwclnmtdeqaiacldtvkpkfapfrdasyapvlaklhvryvisgakqaelngfidvhtfdldtydhfervengkp

NWIVPNKYlafsgphpkskieNGYPYHApeAYFPYFRKHNITSIVRLNkkiYDARRFTD-AGFDHYDLFFIDGSTPSDSI-LQKFLAISES---SEGSLA
. | |. |              |.. .|    .. ......| ||.|.   .|  .||  .|. .......|...|. .. ..|.. . |.|.|  .|||
seilphly-------------lgsllaa--knlewlkelgvtkivnlt---ddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVl

VHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPgSVIGPQQHYMEEKQA
|||.||.|||| .|.||. ..|. | ..|.|..|| .|| |.|..... ..   
VHCkaGkgRsgtliiaYlmksegltleealdwvrskRp-gvitpnqgflkqlkd

Phosphatase spur_CDC14.AA Subfamily.PRL.PD 209-326 25 1.9e-17 54.9 In-house 16-137 (140) Show / Hide
Range on Protein: 209-326
Range on HMM: 16-137/140
Sequence Identity: 25% (31 aa)

AYFPYFRKHNITSIVRLNKKIYDARRFTDAGFDHYDLFFIDGSTPSDSILQKFLAI-----SESSEGSLAVHCKAGLGRTGTLIGCYIMKHfRFTAAEVI
.   ..|.|....||  .  ||| .. ..| .  || | ||..|........|..     .|... ..|||| |||||.  |.   .. ...  . . ..
kfieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea-Gmkyedav

AWMRICRPGSVIGPQQHYMEEKQ
|  | |..   | ...|. .   
efirekrrgainskqlkflekyk

Phosphatase spur_CDC14.AA Subfamily.PTPDC1.PD 230-317 39 4.7e-16 50.4 In-house 125-214 (229) Show / Hide
Range on Protein: 230-317
Range on HMM: 125-214/229
Sequence Identity: 39% (35 aa)

YDARRFTDAGFDHYDLFFIDGSTPS-DSILQ--KFLAISEsSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPGSVIGP
||   .  .|  .|   . | ...| ..||.  | .. .  .|| .|||| ||||||| || ||.. . |.||.| |  .|  || |.   
YdpeelmrqgiyfynfglkDygvasleriLdivkvvdfal-eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtr

Phosphatase spur_CDC14.AA Subfamily.DSP23.PD 260-319 40 1.1e-15 49.3 In-house 57-116 (128) Show / Hide
Range on Protein: 260-319
Range on HMM: 57-116/128
Sequence Identity: 40% (24 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPGSVIGPQQ
. .  .| .|....|||  ||||||||. ||..|. ...|.. || .|  |.||.   .|
riveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsietveq

Phosphatase spur_CDC14.AA Subfamily.PTPMT1.PD 215-315 27 1e-13 42.9 In-house 22-132 (146) Show / Hide
Range on Protein: 215-315
Range on HMM: 22-132/146
Sequence Identity: 27% (30 aa)

RKHNITSIVRLNKKIY------DARRFTDAGFDHYDLFFIDGST-PSDSILQK---FLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIA
.|.|. ..| ||.           . ... | ... |  .|    ||   |..   |.    | . |. |||||| .| .||..||.||..... | .  
ekenvkavvslneeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavk

WMRICRPGSVI
.. .||   . 
flkkkRpqirl

Phosphatase spur_CDC14.AA Subfamily.PTEN.PD 264-309 41 2.8e-11 34.8 In-house 89-135 (305) Show / Hide
Range on Protein: 264-309
Range on HMM: 89-135/305
Sequence Identity: 41% (18 aa)

ISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAA-EVIAWMRIC
..|...   ||||||| ||||..| .|..|.  .. | | .|.    
LkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydek

Phosphatase spur_CDC14.AA Subfamily.DSP11.PD 227-324 22 3.1e-09 28.2 In-house 32-134 (141) Show / Hide
Range on Protein: 227-324
Range on HMM: 32-134/141
Sequence Identity: 22% (23 aa)

KKIYDARRFTDAGFDHYDLFFIDGSTPSDSILQKFLA-------ISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRpGSVIGpQQ
.. |. . .|| |  .. |.    ..|.. ...|| .        .. ..  ..|||  |. ||| ||  |....  . . . |  .  .||  .  ...
dryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeear-Ghsle-re

HYMEE
|.|. 
nyled

Phosphatase spur_CDC14.AA Subfamily.RNGTT.PD 217-324 20 7.9e-09 26.8 In-house 19-132 (140) Show / Hide
Range on Protein: 217-324
Range on HMM: 19-132/140
Sequence Identity: 20% (23 aa)

HNITSIVRLN--KKIYDARRFTDAGFDHYDLFF-IDGSTPSDSILQKFLAISES-----SEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRI
...  .. |   .. ||.. ... |  .  |     | .|.    ..|. . ..      .  ..|||  |  ||| || .|....  ... .| .  .|
vklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalfak

CRPGSVIgpQQHYMEE
|  .   ...|..|  
arppGiy--kedylke

Phosphatase spur_CDC14.AA Subfamily.DSP19.PD 259-322 26 1.8e-08 25.8 In-house 69-130 (139) Show / Hide
Range on Protein: 259-322
Range on HMM: 69-130/139
Sequence Identity: 26% (17 aa)

QKFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPgsVIGPQQHYM
..|.  . |..| . |||.||  |. ...  |.||. . .  . .  .|  ||   | | . ..
ldFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearp--cikPneGFi

Phosphatase spur_CDC14.AA Subfamily.DSP10.PD 266-322 30 2.4e-08 25.4 In-house 78-132 (141) Show / Hide
Range on Protein: 266-322
Range on HMM: 78-132/141
Sequence Identity: 30% (17 aa)

ESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPgsVIGPQQHYM
. .... |||.||. |. |..  |.|||.. .  |   ...  ||  .| |   .| 
rkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekrP--iisPnlnfm

Phosphatase spur_CDC14.AA Subfamily.DSP1.PD 259-323 26 2.8e-08 25.4 In-house 69-131 (139) Show / Hide
Range on Protein: 259-323
Range on HMM: 69-131/139
Sequence Identity: 26% (17 aa)

QKFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRpgSVIGPQQHYME
.|.   ....|   |||.||. |. |..  |.||. ...  |   ...  |  |.| |   ... 
idfidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrr--siisPnfgfvg

Phosphatase spur_CDC14.AA DSPc 260-301 30 9e-08 28.95 Pfam 76-117 (151) Show / Hide
Range on Protein: 260-301
Range on HMM: 76-117/151
Sequence Identity: 30% (13 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAE
.|..  ... |   |||.||. |...|. .|.|| ..... |
DFIDDCRQKGGKVLVHCQAGISRSACLCIAYLMKYRNMSYNE

Phosphatase spur_CDC14.AA Subfamily.DSP14.PD 266-318 30 1.5e-07 23.0 In-house 75-125 (138) Show / Hide
Range on Protein: 266-318
Range on HMM: 75-125/138
Sequence Identity: 30% (16 aa)

ESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPgsVIGPQ
....|   |||.||  |  .|.  |.||. . . .|   ... .||  .| | 
kkkgGktlvhCvaGvsRsAslvlaylmkyeklsLreayklvksaRp--iirPn

Phosphatase spur_CDC14.AA Subfamily.DSP12.PD 261-323 25 2.1e-07 22.6 In-house 73-133 (143) Show / Hide
Range on Protein: 261-323
Range on HMM: 73-133/143
Sequence Identity: 25% (16 aa)

FLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRpgSVIGPQQHYME
|.  . . ||.. |||.||. |  |..  |.||. ..   . .  ..  .  . | | . ..|
FieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekk--keiepNegFle

Phosphatase spur_CDC14.AA Subfamily.DSP15.PD 260-317 29 2.5e-07 22.2 In-house 69-124 (138) Show / Hide
Range on Protein: 260-317
Range on HMM: 69-124/138
Sequence Identity: 29% (17 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRpgSVIGP
.|.  .   .|.  ||| ||. |. ||.  |||    ..  ...  .. .|  || .|
dfihkcrleggnvlvhclaGisrsvtlvvayimtvtelswedalkavkaar--svanP

Phosphatase spur_CDC14.AA Subfamily.Slingshot.PD 260-324 25 2.8e-07 21.9 In-house 70-132 (139) Show / Hide
Range on Protein: 260-324
Range on HMM: 70-132/139
Sequence Identity: 25% (16 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRpgSVIGPQQHYMEE
||.  . ... .. |||| |. |. . .  | ||.....  | .....  |  |.| | . ... 
kfiekakekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerr--siikpnkgflkq

Phosphatase spur_CDC14.AA Subfamily.N13.PD 264-322 27 2.9e-07 21.7 In-house 186-248 (259) Show / Hide
Range on Protein: 264-322
Range on HMM: 186-248/259
Sequence Identity: 27% (17 aa)

ISESSEGSLAVHCKAGLGRTGTLIGCYIM-----KHFRFTAAEVIAWMRICRPgSVIGPQQHYM
....| ..||| ||.||.|.||  ...     ..  |   |..  .|  |  .|.  .. |.  
llqtdagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrq-gvvqtkdqyi

Phosphatase spur_CDC14.AA Subfamily.N_Nematode_4.PD 257-293 34 4.2e-07 21.1 In-house 183-220 (264) Show / Hide
Range on Protein: 257-293
Range on HMM: 183-220/264
Sequence Identity: 34% (13 aa)

ILQKFLAIS-ESSEGSLAVHCKAGLGRTGTLIGCYIMK
... . |.  ...|. . ||| ||.||| ||.| .. .
viklykavkkkkkekPivvhcsaGvGrtatlvGidyat

Phosphatase spur_CDC14.AA Subfamily.DSP8.PD 260-320 30 6e-07 21.0 In-house 72-130 (143) Show / Hide
Range on Protein: 260-320
Range on HMM: 72-130/143
Sequence Identity: 30% (18 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRpgSVIGPQQH
.|.   .|..|.  ||| ||  |. |.. .||||.....  |   ...  |  . | |.  
efidkarsangkvlvhclaGisrsatvaiayimktlemsldeayrfvkekr--ptispnln

Phosphatase spur_CDC14.AA Subfamily.R_Nematode_3.PD 260-319 19 7.5e-07 20.2 In-house 189-254 (267) Show / Hide
Range on Protein: 260-319
Range on HMM: 189-254/267
Sequence Identity: 19% (13 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIG----CYIMKHF--RFTAAEVIAWMRICRPGSVIGPQQ
. . . |.|. .. |||..| .|..||      .  . .    .. ...|  .| .|.| .  ...
elikfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtele

Phosphatase spur_CDC14.AA Subfamily.DSP3.PD 226-322 23 1e-06 20.2 In-house 46-139 (148) Show / Hide
Range on Protein: 226-322
Range on HMM: 46-139/148
Sequence Identity: 23% (23 aa)

NKKIYDARRFTDAGFDHYDLFFIDGSTPSDSIlQKFLAIS-ESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRpgsVIGPQQHYM
....|.    .  |..  |.. .| |.  ..   .|.. . ....| . |||..|. |. ||.  |.| . ..|. | |  .|  |    |.| . ..
daefYkdleikylGvevsDvpefdlskyfeea-adfidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkr---eilPneGfl

Phosphatase spur_CDC14.AA Subfamily.N20.PD 264-320 33 1.3e-06 19.6 In-house 182-245 (257) Show / Hide
Range on Protein: 264-320
Range on HMM: 182-245/257
Sequence Identity: 33% (21 aa)

ISE--SSEGSLAVHCKAGLGRTGTL-----IGCYIMKHFRFTAAEVIAWMRICRPGSVIGPQQH
.      | . ||| ||.|||| .     . | |.|   |   ...| ||  | | |   .|. 
yarkshltgpmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqy

Phosphatase spur_CDC14.AA Subfamily.TPIP.PD 268-301 42 2.1e-06 19.0 In-house 36-69 (245) Show / Hide
Range on Protein: 268-301
Range on HMM: 36-69/245
Sequence Identity: 42% (14 aa)

SEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAE
|  .|.||| | |||||.. .....   |. || 
lenvvaihckGGkgrtGtivcalliaseifltae

Phosphatase spur_CDC14.AA Subfamily.N_Choan_2.PD 266-324 28 2.7e-06 18.2 In-house 190-258 (266) Show / Hide
Range on Protein: 266-324
Range on HMM: 190-258/266
Sequence Identity: 28% (19 aa)

ESSE-----GSLAVHCKAGLGRTGTLIGC-----YIMKHFRFTAAEVIAWMRICRPGSVIGPQQHYMEE
....     . | ||| ||.|||||||        . .. .   ...|. .|  |.  |  |.|. .  
rvrkeldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyelly

Phosphatase spur_CDC14.AA Subfamily.N12.PD 258-292 40 2.8e-06 18.1 In-house 188-222 (270) Show / Hide
Range on Protein: 258-292
Range on HMM: 188-222/270
Sequence Identity: 40% (14 aa)

LQKFLAISESSEGSLAVHCKAGLGRTGTLIGCYIM
....  . ||..  |.||| || |||||.|   ..
ielvrelqesedaPlvvhCsaGvGrtGtiiaidyv

Phosphatase spur_CDC14.AA Subfamily.N_Nematode_1.PD 260-293 44 2.8e-06 18.3 In-house 187-221 (265) Show / Hide
Range on Protein: 260-293
Range on HMM: 187-221/265
Sequence Identity: 44% (15 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIGC-YIMK
..|.  ..|.| ..||| ||.|||||...  ||. 
elleavrgskgPivvhCsaGiGrtGtivaieyild

Phosphatase spur_CDC14.AA PTPc_motif 236-329 22 3e-06 20.93 SMART 1-92 (92) Show / Hide
Range on Protein: 236-329
Range on HMM: 1-92/92
Sequence Identity: 22% (22 aa)

TDAGFDHYDLFFI---DGSTPSDSILQKFLAISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICRPGSVIGPQQHYMEEKQAAM
|   . ...       | ..|. . . .|..  ..   .. ||| || |||||... ..| .  .   ...  || .|||.|   .|     .  . 
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK---PIVVHCSAGCGRTGTFCAIDMMMQQ-VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE

Phosphatase spur_CDC14.AA Subfamily.RK.PD 263-293 45 3.1e-06 18.0 In-house 192-223 (267) Show / Hide
Range on Protein: 263-293
Range on HMM: 192-223/267
Sequence Identity: 45% (14 aa)

AIS-ESSEGSLAVHCKAGLGRTGTLIGCYIMK
. . |..|| . ||| || ||.|| | . |. 
ksqeeeeeGrivvhClaGaGrsGtfiaidivl

Phosphatase spur_CDC14.AA Subfamily.R_Nematode_2.PD 260-322 26 3.6e-06 17.9 In-house 184-251 (261) Show / Hide
Range on Protein: 260-322
Range on HMM: 184-251/261
Sequence Identity: 26% (18 aa)

KFLAISESSEGSLAVHCKAGLGRTGTLIGCY-----IMKHFRFTAAEVIAWMRICRPGSVIGPQQHYM
. | .   ||  . ||| ||.|||...||       ....   . .| .. .|  |. ..   .| | 
eLlelvkksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtesqlyw

Phosphatase spur_CDC14.AA Subfamily.DSP6.PD 264-323 25 3.8e-06 18.1 In-house 76-133 (141) Show / Hide
Range on Protein: 264-323
Range on HMM: 76-133/141
Sequence Identity: 25% (15 aa)

ISESSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRicRPGSVIGPQQHYME
. |.. .. ||| ||. |. |.. .|.||.  ..  .  ....  .  | | |  ..|. 
earskkskvlvhclaGvsrsvtvtlaylmkklalslndaydlvk--kkksnisPnfnfmg

Phosphatase spur_CDC14.AA Subfamily.LRR-DSP.PD 267-310 30 4e-06 18.2 In-house 75-118 (137) Show / Hide
Range on Protein: 267-310
Range on HMM: 75-118/137
Sequence Identity: 30% (13 aa)

SSEGSLAVHCKAGLGRTGTLIGCYIMKHFRFTAAEVIAWMRICR
.| . .||.||. |. ||. .|.||. ...  | .  .   |  
rekggvlihcragvsrsatlviaylmkknslkfkealdlvikkr

Phosphatase spur_CDC14.AA Subfamily.RB.PD 267-296 38 4.8e-06 17.7 In-house 191-221 (261) Show / Hide
Range on Protein: 267-296
Range on HMM: 191-221/261
Sequence Identity: 38% (12 aa)

SSEGSLAVHCKAGLGRTGTLIGCY-IMKHFR
.|.. . ||| ||.||||| |    .... .
askkPivvHCsaGvGRtGtfialdrllqaie

Sequence
Name Sequence Type Origin Length Description Download
spur_CDC14.AA Protein None 534 None Fasta, JSON
spur_CDC14.NA RNA None 1602 None Fasta, JSON
spur_CDC14.AA.PD_193-329 Protein Phosphatase Domain None 137 None Fasta, JSON