• Phosphatome.Net

Gene spur_DUSP1

spur_DUSP1
Species: S.purpuratus
Alias: spur_DUSP1
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP1
Protein domain

Protein domains of spur_DUSP1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Rhodanese spur_DUSP1.AA RHOD 12-139 17 1e-06 29.18 SMART 1-94 (94) Show / Hide 
Range on Protein: 12-139
Range on HMM: 1-94/94
Sequence Identity: 17% (22 aa)

GSRLKSWFSTEEFRVLLLDCRSFVCYNSLHIVDALNVHCPLLLKRRSNGPLPVDHLVTCADARSRLLAGFYQAVLVYDEESVQTASEVSQGNMTWVLETL
   .. ..  .  .....|||..  |.  ||  |.|.... ||.|                    |  .  . | ||. .|  ..    .. ..|.|. .
V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR--------------------LGIDKDKPVIVYC-RSGNRS----APRAAWWLREA

FQEPLLQLSVKIFSLVGGFNQFSVEFPS
  .       ... | ||.. .. ..| 
GYK-------NVYILDGGWKEWKRACPP
Phosphatase spur_DUSP1.AA Family.DSP.PD 172-313 43 1.9e-40 130.6 In-house 102-246 (387) Show / Hide 
Range on Protein: 172-313
Range on HMM: 102-246/387
Sequence Identity: 43% (62 aa)

YECNAPVRLLPHLYLGSNFHASRLAVLEEHGITAVLNVSRLPNYFPT--CFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSAT
|.. |.. ||||||||  .|. |  |.|.|.|...|..  .. |     ..|..| .||..  .|  .||.| .||.. ...||.|||||.||..||.|.
vengkpseilphlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgt

ICLAYLMKVRQIRLEEAFEFVRSERT-VISPNLAFMLQLLRFENE
. ||||| ... ||||...||| |  || ||  |. || ..|.| 
liiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdleke
Phosphatase spur_DUSP1.AA Subfamily.DSP1.PD 177-312 60 9.2e-66 211.4 In-house 2-138 (139) Show / Hide 
Range on Protein: 177-312
Range on HMM: 2-138/139
Sequence Identity: 60% (83 aa)

PVRLLPHLYLGSNFHASRLAVLEEHGITAVLNVSR-LPNYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAYL
||..|..|||||..|||.|..|.|..|||.||||. |||.|...|.|..| |.||..||.. .||||..||||.....|||||||.|||||||||.||||
pveildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayL

MKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
|| ...|||||||||...|..||||..|. |||.||.
mkekkvrleeafefvkqrrsiisPnfgfvgqLlefek
Phosphatase spur_DUSP1.AA DSPc 176-313 34 1.9e-54 188.13 SMART 1-172 (172) Show / Hide 
Range on Protein: 176-313
Range on HMM: 1-172/172
Sequence Identity: 34% (60 aa)

APVRLLPHLYLGSNFHAS--RLAVLEEHGITAVLNVSR-LPN-----------------YFPTCFRYMQIL-VDD-------NTDADLLPWFEEANNFID
.|.. .|||||||. |..  ... |..|.||.|.||..  |.                 |..  |.||.|  .||       |. ......|.|...||.
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

SIERCKGRVLVHCHAGISRSATICLAYLMKVRQIRLEEAFEFV-----RSER-TVISPNLAFMLQLLRFENE
. .. .|.||||| ||||||||.| ||||| ... ...|..||     .. |   |.||. |. ||. .|. 
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase spur_DUSP1.AA DSPc 184-313 41 3.3e-54 190.42 Pfam 1-151 (151) Show / Hide 
Range on Protein: 184-313
Range on HMM: 1-151/151
Sequence Identity: 41% (62 aa)

LYLGSNFHAS-RLAVLEEHGITAVLNVS-RLPN---YFPTCFRYMQIL-VDD---------NTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSA
|||||. |.. ..| |..||||.|.|..  .||   | .  |.||.|  |.|         |..... ..|..| .|||. .. .|.||||| |||||||
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA

TICLAYLMKVRQIRLEEAFEFV-----RSER-TVISPNLAFMLQLLRFENE
..|.||||| |.....||..||     .. |  .||||  |. ||. .|. 
CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase spur_DUSP1.AA Subfamily.DSP10.PD 178-312 47 5.7e-45 143.9 In-house 3-140 (141) Show / Hide 
Range on Protein: 178-312
Range on HMM: 3-140/141
Sequence Identity: 47% (65 aa)

VRLLPHLYLGSNFHASRLAVLEEHGITAVLNVS-RLPNYFP--TCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAY
...||.|.||..  |.   .|. .||. ||||  ..||.|     .||..| | |..  .|   |||| .||. . .. .|||||||||||||||. .||
ssilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviay

LMKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
.||  .. |.||..||...| .||||| || |||.||.
vmkhlslslseaykfvkekrPiisPnlnfmGqllefek
Phosphatase spur_DUSP1.AA Subfamily.DSP6.PD 177-312 47 9.7e-45 143.0 In-house 2-140 (141) Show / Hide 
Range on Protein: 177-312
Range on HMM: 2-140/141
Sequence Identity: 47% (66 aa)

PVRLLPHLYLGSNFHASRLAVLEEHGITAVLNVS-RLPNYFPT--CFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLA
||..||.|||||. .|| | ||....|  ||||.  ||| |     ..|.|| ..|.  ..|  .| || .|||   . |  |||||.||.||| |..||
pveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtla

YLMKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
|||| ... |..|...|.. .. ||||. || ||| ||.
ylmkklalslndaydlvkkkksnisPnfnfmgqlldfer
Phosphatase spur_DUSP1.AA Subfamily.DSP8.PD 177-313 45 5.5e-43 137.6 In-house 2-141 (143) Show / Hide 
Range on Protein: 177-313
Range on HMM: 2-141/143
Sequence Identity: 45% (64 aa)

PVRLLPHLYLGSNFHASRLAVLEEHGITAVLNVSRLPNY---FPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLA
| |.||.|||||. ..    .|.. ||. |||.|.  .    . .  |...| | |. . .|||||..| .||| ... .|.|||||.||||||||. .|
ptrilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaia

YLMKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFENE
|.||  .. |.||..||.. |. ||||| |. ||| .|.|
yimktlemsldeayrfvkekrptispnlnflgqLleyeke
Phosphatase spur_DUSP1.AA Subfamily.DSP19.PD 180-312 44 1.9e-41 132.4 In-house 5-138 (139) Show / Hide 
Range on Protein: 180-312
Range on HMM: 5-138/139
Sequence Identity: 44% (59 aa)

LLPHLYLGSNFHASRLAVLEEHGITAVLNVS-RLPNYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAYLMKV
. |.|||||   |. . .|....|| .|||.  .|| ||. |.|..| . |. ...|| ...|| .||..  . .|||||||.||.||||.. .||||| 
vkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkd

RQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
....||.|.| ||..|  |.||  |. || ..|.
eelslekalekvrearpcikPneGFikqLkeyea
Phosphatase spur_DUSP1.AA Subfamily.Slingshot.PD 177-311 42 1.2e-39 126.6 In-house 2-137 (139) Show / Hide 
Range on Protein: 177-311
Range on HMM: 2-137/139
Sequence Identity: 42% (57 aa)

PVRLLPHLYLGSNFHASRLAVLEEHGITAVLNVSR-LPNYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAYL
. ..  ||||||.. || |  |.|.|.. .|||.. . |.||  |.|..| | |....|||....|. .||. . . . .||||||.||||.. .|| ||
askifdhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviaya

MKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFE
  .. ||||.|.|...|..| || .|. ||  .|  
mkeyelsleealeyvkerrsiikpnkgflkqlkvye
Phosphatase spur_DUSP1.AA Subfamily.DSP14.PD 179-312 36 6.2e-38 121.2 In-house 4-137 (138) Show / Hide 
Range on Protein: 179-312
Range on HMM: 4-137/138
Sequence Identity: 36% (49 aa)

RLLPHLYLGsNFHASRLAVLEEHGITAVLNVS-RLPNYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAYLMK
.. ..|||.    |.. ..|....||...||. .||.   . .....| |.|. .|.| ..|.|. . |..... .|..|||| ||.||||...||||||
eitesLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylmk

VRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
 ... |.||...|.|.| .| ||  |  || ..|.
yeklsLreayklvksaRpiirPnvGFwkqlidyEk
Phosphatase spur_DUSP1.AA Subfamily.LRR-DSP.PD 177-312 39 4.9e-37 118.1 In-house 2-136 (137) Show / Hide 
Range on Protein: 177-312
Range on HMM: 2-136/137
Sequence Identity: 39% (54 aa)

PVRLLPHLYLGSNFHASRLAVLEEHGITAVLNVSRLPNYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSiERCKGRVLVHCHAGISRSATICLAYLM
|  ....||||.   |   ..|.. ..| .| |. .  ..|  |.|. | ..|  .||.  .|.| | |||.  | || ||.|| ||.|||||. .||||
pdliidklylgcresamnksilkdnnvthilavadfkplypdlfkyliidiedvdeadiyqhfkemnafide-grekggvlihcragvsrsatlviaylm

KVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
| ......||...| ..|. | ||  |. ||..||.
kknslkfkealdlvikkrpriypnrgfldqlkkfek
Phosphatase spur_DUSP1.AA Subfamily.DSP12.PD 179-312 37 4.5e-35 112.1 In-house 4-140 (143) Show / Hide 
Range on Protein: 179-312
Range on HMM: 4-140/143
Sequence Identity: 37% (52 aa)

RLLPHLYLGSNFHASRLAVLEEHGITAVLNVSRLP--NYFPT-CFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAYL
..|| ||||.  ..   . |.|  ||.|| | . .  ..  .    . .| ..|. ..||| ...||..||..    .| |||||.||.|||.||..|||
eilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAYl

MKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
|| ... ||.|...|.. .  |.||  |. ||  ||.
mkkeklslekAlklvkekkkeiepNegFleQLklfek
Phosphatase spur_DUSP1.AA Subfamily.DSP15.PD 180-312 38 1e-31 101.0 In-house 5-137 (138) Show / Hide 
Range on Protein: 180-312
Range on HMM: 5-137/138
Sequence Identity: 38% (51 aa)

LLPHLYLGSNFHASRLAVLEEHGITAVLNVSRLPNYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAYLMKVR
.|| ||.|.   |.  . |||. || .| .   .. .   ..|. | ..|  | ||  .|.|...|| .    .| ||||| |||||| |.. ||.| | 
vlpGlyvGnfrdakdkeqleenkithilsihdsakplledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimtvt

QIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
..  |.|.. |.. |.|  ||. |  ||  ||.
elswedalkavkaarsvanPnvGfrrqlqefek
Phosphatase spur_DUSP1.AA Subfamily.DSP3.PD 181-312 38 1.7e-30 97.1 In-house 6-147 (148) Show / Hide 
Range on Protein: 181-312
Range on HMM: 6-147/148
Sequence Identity: 38% (55 aa)

LPHLYLGSNFHASRLAVLEEHGITAVLNVSRL---------PNYFPT-CFRYMQILVDDNTDADLLPWFEEANNFIDS-IERCKGRVLVHCHAGISRSAT
|..|.| .  |.    |.. ||| ||| ..          ....     .|. . |.|  ..||  .|||| .|||. ... .|.|||||..|||||||.
ypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsat

ICLAYLMKVRQIRLEEAFEFVRSERTvISPNLAFMLQLLRFEN
 |||||  |.. |.|| . ||..|. | ||  |. |||.... 
lvlayLmirrkltlkeaiktvrkkre-ilPneGflkqLlelde
Phosphatase spur_DUSP1.AA Subfamily.STYX.PD 180-311 37 3.7e-27 86.3 In-house 5-144 (146) Show / Hide 
Range on Protein: 180-311
Range on HMM: 5-144/146
Sequence Identity: 37% (53 aa)

LLPHLYLGSN--FHASRLAVLEEHGITAVLNVSRLP------NYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATIC
.|| |.||       |.| ||.||||| .. . . .        ||  |||. . | |||  ... .. ....|||.  .  |.||||  |||||||.. 
ilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalv

LAYLMKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFE
.||.|.   ..  ||| .|.  | .|.||  |. ||  .|
iayimetyglkyreafayvqerrfcinpnegfvsqlkeye
Phosphatase spur_DUSP1.AA Subfamily.STYXL1.PD 177-312 33 9.9e-25 78.7 In-house 2-142 (143) Show / Hide 
Range on Protein: 177-312
Range on HMM: 2-142/143
Sequence Identity: 33% (47 aa)

PVRLLPH-LYLGSNFHASRLAVLEEHGITAVLNVSRLPNYF----PTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATIC
|| .||. ||||   .|   |. ..  . |..|||   . .    . . . ..| |.|. .||||. ..|. .||.. .. .  |||  .||||||.. .
PvevlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaavi

LAYLMKVRQIRLEEAFEFVRSERTVISPNLAFMLQLLRFEN
||||  ..| |..|.....  .  . || ||. || ..|. 
iaylmyskkitlkkaykylkkckenvkPnrafveqlseWek
Phosphatase spur_DUSP1.AA Subfamily.PTPMT1.PD 197-300 32 1.6e-17 54.9 In-house 32-133 (146) Show / Hide 
Range on Protein: 197-300
Range on HMM: 32-133/146
Sequence Identity: 32% (33 aa)

VLEEHGITAVLNVSRlpNYFPTCFRYMQILVDDNTDADLLPWFEEANNFIDSIERCKGRVLVHCHAGISRSATICLAYLMKVRQIRLEEAFEFVRSERTV
. ||. ..|. | ..  ..  .  ...|. . | |.|  |   ||. .||...   . .| ||| || .||||.  .|||| ...  |||.|... |  |
lneeyelkalanste--ewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpq

ISPN
  . 
irlk
Phosphatase spur_DUSP1.AA Subfamily.CDC14.PD 243-304 29 5.4e-12 37.2 In-house 188-251 (258) Show / Hide 
Range on Protein: 243-304
Range on HMM: 188-251/258
Sequence Identity: 29% (19 aa)

NNFIDSIERCKGRVLVHCHAGISRSATICLAYLMKVRQIRLEEAFEFVRSER--TVISPNLAFM
..|.. .|...| . |||.||. | .|.  .||.|  ..  .|.  ..|  |  .||.|   ..
kkfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtyl
Phosphatase spur_DUSP1.AA Subfamily.PTPDC1.PD 253-295 39 7e-10 30.0 In-house 166-208 (229) Show / Hide 
Range on Protein: 253-295
Range on HMM: 166-208/229
Sequence Identity: 39% (17 aa)

KGRVLVHCHAGISRSATICLAYLMKVRQIRLEEAFEFVRSERT
.|.. ||||||  |   .  .||. ....  ||| ..|||.|.
egkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp
Phosphatase spur_DUSP1.AA Subfamily.R_Nematode_3.PD 241-273 48 4.1e-09 27.4 In-house 186-218 (267) Show / Hide 
Range on Protein: 241-273
Range on HMM: 186-218/267
Sequence Identity: 48% (16 aa)

EANNFIDSIERCKGRVLVHCHAGISRSATICLA
|| . |. .| .|  |.|||..|||||||.  .
ealelikfveksktpvvVHCsdGisRsatlaai
Phosphatase spur_DUSP1.AA Subfamily.PTEN.PD 255-295 36 2e-07 21.9 In-house 96-137 (305) Show / Hide 
Range on Protein: 255-295
Range on HMM: 96-137/305
Sequence Identity: 36% (15 aa)

RVLVHCHAGISRSATICLAYLMKVRQIRLE-EAFEFVRSERT
| |||.||  |. ..  |||.|  . . . || ..  ..|| 
VvavHCkaGkGRtGvmicayLlksgikksadealaiydekRt
Phosphatase spur_DUSP1.AA Subfamily.DSP23.PD 245-294 30 9.9e-07 20.2 In-house 58-107 (128) Show / Hide 
Range on Protein: 245-294
Range on HMM: 58-107/128
Sequence Identity: 30% (15 aa)

FIDSIERCKGRVLVHCHAGISRSATICLAYLMKVRQIRLEEAFEFVRSER
..  |. .. | |||  |. |. |.   ||.| ...  ..|   || .| 
iveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrr
Phosphatase spur_DUSP1.AA Subfamily.Laforin.PD 254-297 34 5.4e-06 17.4 In-house 105-148 (165) Show / Hide 
Range on Protein: 254-297
Range on HMM: 105-148/165
Sequence Identity: 34% (15 aa)

GRVLVHCHAGISRSATICLAYLMKVRQIRLEEAFEFVRSERTVI
.| ||| ||. ||..|   .|. | .  |     |. . | |. 
hivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv
Sequence
Name Sequence Type Origin Length Description Download
spur_DUSP1.AA Protein None 314 None Fasta, JSON
spur_DUSP1.NA RNA None 942 None Fasta, JSON
spur_DUSP1.AA.PD2_176-313 Protein Phosphatase Domain None 138 None Fasta, JSON