• Phosphatome.Net

Gene spur_DUSP14

spur_DUSP14
Species: S.purpuratus
Alias: spur_DUSP14
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP14
Protein domain

Protein domains of spur_DUSP14.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase spur_DUSP14.AA Family.DSP.PD 10-164 35 2.2e-37 119.8 In-house 105-259 (387) Show / Hide 
Range on Protein: 10-164
Range on HMM: 105-259/387
Sequence Identity: 35% (56 aa)

HLINEITNSLYLTSAYGASSPTALRAKGITCIINISLSfQTPTPKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSV
....||. .||| |.  |.. ..|. .|.| |.|..   ..   |  .|...||..|| .. .|  .|... | |..... .|. .|||.||..||.. .
gkpseilphlylgsllaaknlewlkelgvtkivnltdd-kpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtli

MAYLMKYEHLTLKQAHVHVKSRRP-VIRPNPGFWKQLITYEHRLYGKNSVKMMYTH
.|||||.|.|||..|  .|.|.|| ||.|| ||.|||  .|...   .| .|.. .
iaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrf
Phosphatase spur_DUSP14.AA Subfamily.DSP14.PD 12-151 55 9.3e-62 197.7 In-house 2-138 (138) Show / Hide 
Range on Protein: 12-151
Range on HMM: 2-138/138
Sequence Identity: 55% (78 aa)

INEITNSLYLTsAYGASSPTALRAKGITCIINISLsfQTPTPKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMA
..|||.||||. ...|.....|..|.||.|.|..   ..|..||.|.. |.|.|.| |.|.|  |||..||||..||| ||||.|||.||.||||| |.|
lseitesLyls-gaaalkkeklkkkkitlivnvtt--elpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvla

YLMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEHR
||||||.|.|..|. .|||.||.||||.|||||||.||..
ylmkyeklsLreayklvksaRpiirPnvGFwkqlidyEkk
Phosphatase spur_DUSP14.AA DSPc 11-151 29 4.3e-41 143.74 SMART 1-172 (172) Show / Hide 
Range on Protein: 11-151
Range on HMM: 1-172/172
Sequence Identity: 29% (51 aa)

LINEITNSLYLTSAYGAS--SPTALRAKGITCIINISLSFQTP---------------TPKLRDIEFVRIA-VDD-------IPTAQLGVHFDRIADKIN
 . |||. ||| |.....  .|  | ...|| .|| . ..  .               ...  ......|  .||        .....  .|.. .| |.
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

SVKKGGGKTVVHCYAGRSRSASSVMAYLMKYEHLTLKQAHVHV-----KSRR-PVIRPNPGFWKQLITYEHR
.... |||  |||.|| ||||. ..||||||.....  |  .|     |.|| | |.|| .||.||. .| .
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase spur_DUSP14.AA Subfamily.DSP1.PD 13-150 41 8.7e-40 126.6 In-house 3-138 (139) Show / Hide 
Range on Protein: 13-150
Range on HMM: 3-138/139
Sequence Identity: 41% (57 aa)

NEITNSLYLTSAYGASSPTALRAKGITCIINISLSFQTPTPKLrdIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMAY
.|| . ||| ||. ||.   |.. .|| ..|.| . .   ..|   .. .| |.| ..|..  .|. ..| |.|||| ||. .||| || ||||. |.||
veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeel--fkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlay

LMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
||| ....|..|. .||.|| .| || || .||...|.
LmkekkvrleeafefvkqrrsiisPnfgfvgqLlefek
Phosphatase spur_DUSP14.AA DSPc 19-151 33 1.3e-37 132.74 Pfam 1-151 (151) Show / Hide 
Range on Protein: 19-151
Range on HMM: 1-151/151
Sequence Identity: 33% (50 aa)

LYLTSAYGAS-SPTALRAKGITCIINISLSFQ-TPTPKLRDIEFVRIA-VDD---------IPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSA
||| |..... .|  | ..||| .|| . .   . ...  .... .|  |.|          .....  .|... | |..... |||  |||.|| ||||
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA

SSVMAYLMKYEHLTLKQAHVHV-----KSRR-PVIRPNPGFWKQLITYEHR
. ..|||||| ..... |  .|     |.|| |.|.||..||.||. || .
CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase spur_DUSP14.AA Subfamily.DSP19.PD 12-150 37 6.6e-36 113.8 In-house 2-138 (139) Show / Hide 
Range on Protein: 12-150
Range on HMM: 2-138/139
Sequence Identity: 37% (52 aa)

INEITNSLYLTSAYGASSPTALRAKGITCIINISLSFQTPtpKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMA
. |... |||.|   |.. ..|. ..|| |.|..   ..     .|.... | . | | ..|  ..... | |..... .|  .||| ||.||||| |.|
vaevkprlylgsqdvaadkeilkklkitHilnvavgvpnv--fpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvvia

YLMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
|||| |.|.|..|  .|.. || |.|| ||.||| .||.
ylmkdeelslekalekvrearpcikPneGFikqLkeyea
Phosphatase spur_DUSP14.AA Subfamily.Slingshot.PD 14-149 38 7.4e-33 103.9 In-house 4-137 (139) Show / Hide 
Range on Protein: 14-149
Range on HMM: 4-137/139
Sequence Identity: 38% (52 aa)

EITNSLYLTSAYGASSPTALRAKGITCIINISLSFQTPTPKlrDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMAYL
.| . ||| | . ||    |. .|.. |.|..   .   |.  ......| | | ....|  |...  . |. .|. | | .|||| |||||.|.|| ||
kifdhlylGsewnasnleelkengveyilnvtkeidnffpe--kfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviaya

MKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYE
  .|.|..|. .||.|| .|.|| ||.||| .||  
mkeyelsleealeyvkerrsiikpnkgflkqlkvye
Phosphatase spur_DUSP14.AA Subfamily.DSP8.PD 12-152 36 8.5e-33 103.9 In-house 2-142 (143) Show / Hide 
Range on Protein: 12-152
Range on HMM: 2-142/143
Sequence Identity: 36% (52 aa)

INEITNSLYLTSAYGASSPTALRAKGITCIINISLSFQTPTPKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMA
...|.. ||| |   . . ..|...||. ..||| | .     |.. .|.|| | |  . .|  .||.  . |. ...  || .|||.||.||||. ..|
ptrilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaia

YLMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEHRL
|.||. ...| .|. .||..|| | ||  |  ||. ||..|
yimktlemsldeayrfvkekrptispnlnflgqLleyekel
Phosphatase spur_DUSP14.AA Subfamily.DSP10.PD 14-150 34 2.6e-32 102.2 In-house 4-140 (141) Show / Hide 
Range on Protein: 14-150
Range on HMM: 4-140/141
Sequence Identity: 34% (47 aa)

EITNSLYLTSAYGASSPTALRAKGITCIINISLSFQTPTPKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMAYL
.|   |.| .  .|..  ||.  ||....|.  |  .   .  .... || | | .. .|  .|.   . |. ..| |.. .||| || ||||  |.||.
silpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviayv

MKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
||. .|.|..|.  ||..||.| || .|  ||. .|.
mkhlslslseaykfvkekrPiisPnlnfmGqllefek
Phosphatase spur_DUSP14.AA Subfamily.DSP3.PD 12-150 33 1.7e-30 96.4 In-house 2-147 (148) Show / Hide 
Range on Protein: 12-150
Range on HMM: 2-147/148
Sequence Identity: 33% (49 aa)

INEITNSLYLTSAYGASSPTALRAKGITCIINISLS-----FQTPTPKLRD--IEFVRIAVDDIPTAQLGVHFDRIADKINS-VKKGGGKTVVHCYAGRS
..|... .|.. .  |.  . |.. ||| ..| . .      .| .   .|  |... . |.|.|...|  .|.. || |.. ... .|| .||| .| |
vdevypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGis

RSASSVMAYLMKYEHLTLKQAHVHVKSRRPvIRPNPGFWKQLITYEH
|||  |.|||| ...||||.|  .|...|  | || || |||.....
RsatlvlayLmirrkltlkeaiktvrkkre-ilPneGflkqLlelde
Phosphatase spur_DUSP14.AA Subfamily.DSP12.PD 12-150 32 1.7e-29 93.3 In-house 2-140 (143) Show / Hide 
Range on Protein: 12-150
Range on HMM: 2-140/143
Sequence Identity: 32% (45 aa)

INEITNSLYLTSAYGASSPTALRAKGITCIINISLSFQTPTPKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMA
..||.. ||| ..  . ... |.   || .. .    ..   | .. .   | ..| |.. |  |.|.. . |..  . .|. .|||.|||||.. |.||
vseilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviA

YLMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
|||.|.| |..|.  ||. .. |.|| || .||  .|. 
YlmkkeklslekAlklvkekkkeiepNegFleQLklfek
Phosphatase spur_DUSP14.AA Subfamily.LRR-DSP.PD 13-150 34 6.6e-28 87.8 In-house 3-136 (137) Show / Hide 
Range on Protein: 13-150
Range on HMM: 3-136/137
Sequence Identity: 34% (47 aa)

NEITNSLYLTSAYGASSPTALRAKGITCIINISlSFQTPTPKLrdIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGkTVVHCYAGRSRSASSVMAY
..| . ||| .   |   . |. ...| |. ..  |.   |.|  . .. | ..|.. |..  ||...   |.. .. ||  ..|| ||||||. |.|||
dliidklylgcresamnksilkdnnvthilava-dfkplypdl--fkyliidiedvdeadiyqhfkemnafidegrekgg-vlihcragvsrsatlviay

LMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
||...|..|.|   |...|| |.||.|| .||  .|. 
lmkknslkfkealdlvikkrpriypnrgfldqlkkfek
Phosphatase spur_DUSP14.AA Subfamily.DSP6.PD 14-150 31 1e-27 87.1 In-house 4-140 (141) Show / Hide 
Range on Protein: 14-150
Range on HMM: 4-140/141
Sequence Identity: 31% (43 aa)

EITNSLYLTSAYGASSPTALRAKGITCIINISLSFQTPTPKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMAYL
||.. ||| ||  ||   .|.  .|  ..|..   .    .  ......|...|  ...|  .|    . |.  ..   | .|||.|| |||. ..||||
eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl

MKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
|...|.|..|.  ||.... | ||  | .||. .|. 
mkklalslndaydlvkkkksnisPnfnfmgqlldfer
Phosphatase spur_DUSP14.AA Subfamily.DSP15.PD 12-150 34 3.2e-27 85.7 In-house 2-137 (138) Show / Hide 
Range on Protein: 12-150
Range on HMM: 2-137/138
Sequence Identity: 34% (47 aa)

INEITNSLYLTSAYGASSPTALRAKGITCIINIslsFQTPTPKLRDIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMA
.|.. . ||. .  .|.  . |. . || |. |   .... | |.||.. .| ..| |  .|  .|.   | | ...  ||. .||| ||||| . |.||
mnkvlpGlyvGnfrdakdkeqleenkithilsi---hdsakplledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvva

YLMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
.|   .|. ..|   ||. |.|  || || .||  .|. 
yimtvtelswedalkavkaarsvanPnvGfrrqlqefek
Phosphatase spur_DUSP14.AA Subfamily.STYX.PD 13-149 32 1.2e-19 61.2 In-house 3-144 (146) Show / Hide 
Range on Protein: 13-149
Range on HMM: 3-144/146
Sequence Identity: 32% (45 aa)

NEITNSLYLTS--AYGASSPTALRAKGITCIINISLSFQTP--TPKLR-DIEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSAS
.||   |.|    |   |    |. .||| |. |  . ..    |... .. .. . | | .. ..  .. .. . |..  . ||| .|||| ||||. |
qeilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaa

SVMAYLMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYE
.||.|.   |  ..|. .|. || .| || || .||  ||  
lviayimetyglkyreafayvqerrfcinpnegfvsqlkeye
Phosphatase spur_DUSP14.AA Subfamily.STYXL1.PD 17-150 29 6.8e-19 59.1 In-house 8-142 (143) Show / Hide 
Range on Protein: 17-150
Range on HMM: 8-142/143
Sequence Identity: 29% (40 aa)

NSLYLTSAYGASSPTALRAKGITCIINISLSFQTPTPKLRD-IEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMAYLMK
. |||     | .|.  .   .   .|.|   .     | |  . ..|||.| . |.|  ..... . |.. || |   .|    | ||||. ..|||| 
gklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmy

YEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYEH
....|||.|. ..|  .. ..|| .| .||  .|.
skkitlkkaykylkkckenvkPnrafveqlseWek
Phosphatase spur_DUSP14.AA Subfamily.PTPMT1.PD 58-149 33 4.6e-17 52.8 In-house 53-144 (146) Show / Hide 
Range on Protein: 58-149
Range on HMM: 53-144/146
Sequence Identity: 33% (30 aa)

IEFVRIAVDDIPTAQLGVHFDRIADKINSVKKGGGKTVVHCYAGRSRSASSVMAYLMKYEHLTLKQAHVHVKSRRPVIRPNPGFWKQLITYE
.|....|. |.  |    .  .  . |..|.. | .  ||| |||.|||. | .|||| ..|. ..|. ..|..|| || .   |. |..  
veqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefk
Phosphatase spur_DUSP14.AA Subfamily.DSP23.PD 33-133 23 8e-10 29.5 In-house 9-108 (128) Show / Hide 
Range on Protein: 33-133
Range on HMM: 9-108/128
Sequence Identity: 23% (24 aa)

LRAKGITCIINISLSFQTPTPKLRDIEFVRIAVDDI--PTAQLGVHFDRIADKinsVKKGGGKTVVHCYAGRSRSASSVMAYLMKYEHLTLKQAHVHVKS
|  .||  .....   ....    .. ..|| ..|   |. .  ... || ..    .| ..   |||  |. |. . .  ||.| | |...| . |. |
ladqGirvlvslttegapyseaapsltlrridipdfcPPaleqvarlvrivee---aekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrk

RRP
|. 
rrk
Phosphatase spur_DUSP14.AA Subfamily.PTPDC1.PD 57-133 31 6.4e-09 26.1 In-house 134-208 (229) Show / Hide 
Range on Protein: 57-133
Range on HMM: 134-208/229
Sequence Identity: 31% (24 aa)

DIEFVRIAVDDIPTAQLGVHFDRIadKINSVKKGGGKTVVHCYAGRSRSASSVMAYLMKYEHLTLKQAHVHVKSRRP
.| |  .. .|  .| |    | .  |. .     ||. |||.||. |  . . .||.  ..|| ..|   |.|.||
giyfynfglkDygvasleriLdiv--kvvdfaleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp
Phosphatase spur_DUSP14.AA Subfamily.CDC14.PD 72-133 25 2.2e-08 24.7 In-house 185-240 (258) Show / Hide 
Range on Protein: 72-133
Range on HMM: 185-240/258
Sequence Identity: 25% (16 aa)

QLGVHFDRIADKInsvkkgGGKTVVHCYAGRSRSASSVMAYLMKYEHLTLKQAHVHVKSRRP
..  .| .|..|.       |. .||| ||  | .. . .||.|. ..| ...  ...  ||
ailkkfleiteka------eGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarP
Phosphatase spur_DUSP14.AA Subfamily.Laforin.PD 85-135 28 2.6e-07 21.0 In-house 98-148 (165) Show / Hide 
Range on Protein: 85-135
Range on HMM: 98-148/165
Sequence Identity: 28% (14 aa)

NSVKKGGGKTVVHCYAGRSRSASSVMAYLMKYEHLTLKQAHVHVKSRRPVI
.. . | .  ||| ||  ||.. |  .|.   . .|..   .. ..|||. 
hallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv
Phosphatase spur_DUSP14.AA Subfamily.PTEN.PD 95-123 34 9.4e-06 15.7 In-house 98-126 (305) Show / Hide 
Range on Protein: 95-123
Range on HMM: 98-126/305
Sequence Identity: 34% (10 aa)

VVHCYAGRSRSASSVMAYLMKYEHLTLKQ
.||| ||. |.   ..|||.|. . . ..
avHCkaGkGRtGvmicayLlksgikksad
Sequence
Name Sequence Type Origin Length Description Download
spur_DUSP14.AA Protein None 182 None Fasta, JSON
spur_DUSP14.NA RNA None 546 None Fasta, JSON
spur_DUSP14.AA.PD_11-151 Protein Phosphatase Domain None 141 None Fasta, JSON