Gene spur_DUSP15
spur_DUSP15
Species: S.purpuratus
Alias: spur_DUSP15
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of spur_DUSP15.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | spur_DUSP15.AA | Family.DSP.PD | 3-168 | 30 | 8e-38 | 121.6 | In-house | 105-273 (387) | Show / Hide |
Range on Protein: 3-168 Range on HMM: 105-273/387 Sequence Identity: 30% (51 aa) NGMSEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNaKPIrP----DKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTL ...||.|.....|.... |....| ....|.|... |. || . .||... || . ..| ..| .. .||.... ..|.||.|| ||..|| || gkpseilphlylgsllaaknlewlkelgvtkivnltdd-kpq-ftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtl TVAYMMTVTDYKWEDCLRAVKTCRT-VAHPNFGFQRQLQEYEYSKLAEYKEDIRLKFPEYSPEEDIKKMQA ..||.| ... |..|. |. .| |. ||.|| .||...| .|| . .| . |.| ..| ....... iiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrfvissivqnlgsvev |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP15.PD | 4-140 | 67 | 6.1e-76 | 243.9 | In-house | 1-137 (138) | Show / Hide |
Range on Protein: 4-140 Range on HMM: 1-137/138 Sequence Identity: 67% (92 aa) GMSEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNAKPIRPDKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYM ||..||.|..||||||.||..||..|.|||||||||.|||...|..|||..|.|.| |.|..||.||..|||||||||||||.|||||.||||||.|||. gmnkvlpGlyvGnfrdakdkeqleenkithilsihdsakplledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayi MTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYEY ||||...|||.|.|||..|.||.||.||.|||||.|. mtvtelswedalkavkaarsvanPnvGfrrqlqefek |
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| Phosphatase | spur_DUSP15.AA | DSPc | 4-141 | 28 | 5.2e-44 | 153.44 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 4-141 Range on HMM: 1-172/172 Sequence Identity: 28% (49 aa) GMSEVLKGVFVGNFRDSK--DETQLGNNNITHILSIHDNAK------------------PIRPDKEYLCFS-ADD-------APGQNLIQFFSESNNFIH |.||.......|. ... . .| ..||||... .. . . ....|.. || ...|. |.|.|...||| GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH KCRLEGGNVLIHCLAGVSRSVTLTVAYMMTVTDYKWEDCLRAV-----KTCR-TVAHPNFGFQRQLQEYEYS .|| .||.||.||.||.|||.||..||.| ....|....| | | |||.|..||.|.| DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | spur_DUSP15.AA | DSPc | 12-141 | 27 | 3.7e-37 | 131.12 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 12-141 Range on HMM: 1-151/151 Sequence Identity: 27% (42 aa) VFVGNFRDSK-DETQLGNNNITHILSIHDNAK-PIR---PDKEYLCFS-ADD---------APGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSV ...|.. ... |. .| ...|||... .. . .. ....|.. .| ...|. |.|... .||..|| .||.||.||.||.|||. LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA TLTVAYMMTVTDYKWEDCLRAV-----KTCR-TVAHPNFGFQRQLQEYEYS .|..||.| .. ..... | | | . ||..|.|||.||| CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP19.PD | 6-139 | 34 | 1.2e-35 | 113.3 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 6-139 Range on HMM: 3-137/139 Sequence Identity: 34% (46 aa) SEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNAKPI-RPDKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYMM .|| . ...| .|...| ...|||||.. . . . | .|.. . | | ..|.....|. .||.. | ..| ||.|| ||||||... .||.| aevkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylm TVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE . .. . |..|. |.. | ..|| ||..||.||| kdeelslekalekvrearpcikPneGFikqLkeye |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP12.PD | 5-141 | 32 | 6.2e-35 | 111.3 | In-house | 2-141 (143) | Show / Hide |
Range on Protein: 5-141 Range on HMM: 2-141/143 Sequence Identity: 32% (45 aa) MSEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNAK---PIRPDKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVA .||.|.|...|. .. .....| . .|||.||. .. ........ ...| | ..|.... | ..||.... ..|.||.|||||||||||. .| vseilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviA YMMTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYEYS |.| .. . |. |..||. . ..|| ||..||. .| . YlmkkeklslekAlklvkekkkeiepNegFleQLklfekm |
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| Phosphatase | spur_DUSP15.AA | Subfamily.LRR-DSP.PD | 6-139 | 37 | 6e-33 | 104.5 | In-house | 3-135 (137) | Show / Hide |
Range on Protein: 6-139
Range on HMM: 3-135/137
Sequence Identity: 37% (51 aa)
SEVLKGVFVGNFRDSKDETQLGNNNITHILSIHdNAKPIRPDK-EYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGnVLIHCLAGVSRSVTLTVAYMM
.........| ..... | .||.||||.. . ||. || || ..|.. .. |.| | | ||.. | .|| ||||| |||||| ||..||.|
dliidklylgcresamnksilkdnnvthilava-dfkplypdlfkyliidiedvdeadiyqhfkemnafidegrekgg-vlihcragvsrsatlviaylm
TVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE
|... | |. |. .|| ||. ||. .|
kknslkfkealdlvikkrpriypnrgfldqlkkfe
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP1.PD | 6-139 | 30 | 3.1e-31 | 99.2 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 6-139 Range on HMM: 3-137/139 Sequence Identity: 30% (41 aa) SEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNAKPIRPD-KEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYMM .|.| ...| .. . .| . .||..| . . . .. .| . .| . ... ..|.| ..||.... .|| ||.|| ||.||||. .||.|. veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm TVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE . .. |. || |.. ||||| .|| |.| kekkvrleeafefvkqrrsiisPnfgfvgqLlefe |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP6.PD | 7-140 | 33 | 4.9e-31 | 98.2 | In-house | 4-140 (141) | Show / Hide |
Range on Protein: 7-140 Range on HMM: 4-140/141 Sequence Identity: 33% (46 aa) EVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNAKPI---RPDKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYM |.|. ...|. .|... | . .| ..| . .| . .. .|. ...| ||| .|| |. .|| ..| . .||.|||||||||||.|.||. eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl MTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYEY | . . .| ||. .. ||| | || ..| mkklalslndaydlvkkkksnisPnfnfmgqlldfer |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP10.PD | 5-139 | 31 | 4.6e-30 | 95.2 | In-house | 2-139 (141) | Show / Hide |
Range on Protein: 5-139 Range on HMM: 2-139/141 Sequence Identity: 31% (44 aa) MSEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNA---KPIRPDKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVA .|..| ...|| .|..|. | .|...| . .. . ...| . |.. ||| | |.|. .||.. | .|..||.|| ||.|||.|...| assilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvia YMMTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE |.| .. .. . ||. | . ||..| || |.| yvmkhlslslseaykfvkekrPiisPnlnfmGqllefe |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP8.PD | 5-140 | 32 | 1.4e-29 | 93.8 | In-house | 2-140 (143) | Show / Hide |
Range on Protein: 5-140 Range on HMM: 2-140/143 Sequence Identity: 32% (45 aa) MSEVLKGVFVGNFRDSKDETQLGNNNITHIL--SIHDNA-KPIRPDKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVA . ..|. ...| .|| ||. | ...|...| | . .. . .....| | .|...| .. .|| |.| . |.||.||||| ||| |. .| ptrilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaia YMMTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYEY |.| . . ... | || |. ||. | || ||| yimktlemsldeayrfvkekrptispnlnflgqLleyek |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP14.PD | 5-139 | 28 | 8.2e-29 | 91.3 | In-house | 2-136 (138) | Show / Hide |
Range on Protein: 5-139 Range on HMM: 2-136/138 Sequence Identity: 28% (39 aa) MSEVLKGVFVGnFRDSKDETQLGNNNITHILSIHDNAKPI-RPDKEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYM .||. . .... . .....| ...||.|. . .. .| ... .|.| ..| ..| | . |.. . .||..|.|| |||||| .|..||. lseitesLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlayl MTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE | .. ..||..| . .|| || .||..|| mkyeklsLreayklvksaRpiirPnvGFwkqlidyE |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP3.PD | 6-139 | 31 | 8.3e-27 | 84.8 | In-house | 3-146 (148) | Show / Hide |
Range on Protein: 6-139 Range on HMM: 3-146/148 Sequence Identity: 31% (45 aa) SEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNAK--PIRPD--------KEYLCFSADDAPGQNLIQFFSESNNFIHKCRL-EGGNVLIHCLAGVSR || ..|.||. .||...| . |||.| .. . .. | .|| . ..|.| .| ..|.|. .||.. ..| ||.|| .|.||| devypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisR SVTLTVAYMMTVTDYKWEDCLRAVKTCRTVaHPNFGFQRQLQEYE || .||.| . . .. ...|.. |.. || || .|| |.. satlvlayLmirrkltlkeaiktvrkkrei-lPneGflkqLleld |
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| Phosphatase | spur_DUSP15.AA | Subfamily.Slingshot.PD | 6-139 | 31 | 6.5e-25 | 78.5 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 6-139 Range on HMM: 3-137/139 Sequence Identity: 31% (42 aa) SEVLKGVFVGNFRDSKDETQLGNNNITHILSIHDNAKPIRPDK-EYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYMM |.. . ...| .. . .| .|....|| . . . |.| .|| . | . ..|.... |. .||.|.. .| .||.|| ||||| . .|| | skifdhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayam TVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE ... |..|. || |....|| || .||..|| keyelsleealeyvkerrsiikpnkgflkqlkvye |
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| Phosphatase | spur_DUSP15.AA | Subfamily.STYX.PD | 5-139 | 34 | 7.5e-25 | 78.4 | In-house | 2-144 (146) | Show / Hide |
Range on Protein: 5-139 Range on HMM: 2-144/146 Sequence Identity: 34% (48 aa) MSEVLKGVFVGNFRDSKD--ETQLGNNNITHILSIHDNA--KPIRPD----KEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSV | |.| |.|.| . .. .| .. ||||. | .| . |.|. || . |.. .|.|... . ..|| .. .||.||.|||.||| .| mqeilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsa TLTVAYMMTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE .||.| |. .. . |. | . || || .||.||| alviayimetyglkyreafayvqerrfcinpnegfvsqlkeye |
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| Phosphatase | spur_DUSP15.AA | Subfamily.STYXL1.PD | 8-139 | 24 | 6.5e-19 | 59.4 | In-house | 5-141 (143) | Show / Hide |
Range on Protein: 8-139 Range on HMM: 5-141/143 Sequence Identity: 24% (33 aa) VLK-GVFVGNFRDSKDETQLGNNNITHILSIHDNAKPIRP---D-KEYLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAY || ...||........ . . . . .|... | . | . .| . .|.....| .||.| . || ||. |.|||... .|| vlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiay MMTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYE .| . . .... .| |. .|| .| ||.|.| lmyskkitlkkaykylkkckenvkPnrafveqlseWe |
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| Phosphatase | spur_DUSP15.AA | Subfamily.PTPMT1.PD | 62-138 | 31 | 2.2e-12 | 37.9 | In-house | 67-143 (146) | Show / Hide |
Range on Protein: 62-138 Range on HMM: 67-143/146 Sequence Identity: 31% (23 aa) NLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYMMTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEY . .|. .||.| . .| .| .|| || .|| || .|.|. . .. |. ...|..| . . | |||. pslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqef |
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| Phosphatase | spur_DUSP15.AA | Subfamily.CDC14.PD | 72-123 | 21 | 5e-08 | 23.8 | In-house | 189-240 (258) | Show / Hide |
Range on Protein: 72-123 Range on HMM: 189-240/258 Sequence Identity: 21% (11 aa) NFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYMMTVTDYKWEDCLRAVKTCRT .|.. . |.. .|| ||. | || .|.. .. .... .. .| kfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarP |
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| Phosphatase | spur_DUSP15.AA | Subfamily.DSP11.PD | 62-123 | 25 | 7.4e-08 | 23.2 | In-house | 61-123 (141) | Show / Hide |
Range on Protein: 62-123 Range on HMM: 61-123/141 Sequence Identity: 25% (16 aa) NLI-QFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYMMTVTDYKWEDCLRAVKTCRT . . .| .. ..|..|. .. . .|| || |. | |.. |..|. || ..| ...| edvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearG |
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| Phosphatase | spur_DUSP15.AA | Subfamily.R_Nematode_3.PD | 72-125 | 21 | 3.3e-07 | 20.8 | In-house | 189-248 (267) | Show / Hide |
Range on Protein: 72-125 Range on HMM: 189-248/267 Sequence Identity: 21% (13 aa) NFIHKCRLEGGNVLIHCLAGVSRSVTLTV---AYMMTVT---DYKWEDCLRAVKTCRTVA . |.... .|..|| .|.||| || . .| . .. . . . . ... .| | elikfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRaga |
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| Phosphatase | spur_DUSP15.AA | Subfamily.R_Ecdysozoa.PD | 61-141 | 21 | 1.3e-06 | 18.7 | In-house | 179-262 (269) | Show / Hide |
Range on Protein: 61-141 Range on HMM: 179-262/269 Sequence Identity: 21% (18 aa) QNLIQFFSESNNFIHKCRLEGG--NVLIHCLAGVSRSVTLtVAYMMTVTDYKWEDCLRAVKTCRTVAHPNFGFQRQLQEYEY--S . |... .. ... .. .| | ...|| |||.|| .. || . . | ||.. ..| . . . . ..|. |.. rgllklieqvrelyklnklsgsrsPivvhCsaGvgrsgif-valdlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyr |
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| Phosphatase | spur_DUSP15.AA | Subfamily.Laforin.PD | 50-116 | 21 | 2.4e-06 | 18.2 | In-house | 73-139 (165) | Show / Hide |
Range on Protein: 50-116 Range on HMM: 73-139/165 Sequence Identity: 21% (13 aa) YLCFSADDAPGQNLIQFFSESNNFIHKCRLEGGNVLIHCLAGVSRSVTLTVAYMMTVTDYKWEDCLR |. . .| .. .. . .. ..| .| | .|| ||| || .. . ... | ... yiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqy |
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| Phosphatase | spur_DUSP15.AA | Subfamily.PTPDC1.PD | 78-123 | 28 | 7.1e-06 | 16.5 | In-house | 163-208 (229) | Show / Hide |
Range on Protein: 78-123 Range on HMM: 163-208/229 Sequence Identity: 28% (13 aa) RLEGGNVLIHCLAGVSRSVTLTVAYMMTVTDYKWEDCLRAVKTCRT || |.. .|| || | | .|.. ..... |. .. |. |. aleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp |
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| Phosphatase | spur_DUSP15.AA | Subfamily.PTEN.PD | 83-117 | 29 | 8e-06 | 16.3 | In-house | 96-131 (305) | Show / Hide |
Range on Protein: 83-117 Range on HMM: 96-131/305 Sequence Identity: 29% (10 aa) NVLIHCLAGVSRSVTLTVAYMMTVTDYKWE-DCLRA | .|| || |. ....||... . .| . . |. VvavHCkaGkGRtGvmicayLlksgikksadealai |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| spur_DUSP15.AA | Protein | None | 246 | None | Fasta, JSON |
| spur_DUSP15.NA | RNA | None | 738 | None | Fasta, JSON |
| spur_DUSP15.AA.PD_4-145 | Protein Phosphatase Domain | None | 142 | None | Fasta, JSON |