• Phosphatome.Net

Gene spur_DUSP3A

spur_DUSP3A
Species: S.purpuratus
Alias: spur_DUSP3A
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP3
Protein domain

Protein domains of spur_DUSP3A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase spur_DUSP3A.AA DSPc 1-100 23 3.4e-17 64.35 SMART 13-172 (172) Show / Hide 
Range on Protein: 1-100
Range on HMM: 13-172/172
Sequence Identity: 23% (38 aa)

EYQDTN----------------------------------------------IKYCGLP-VND-------VPGANMKKHFNTAVKFIDEALEQEDGKVLI
 | . .                                              . |...| ..|        ...|. ..|. ...||... .|. ||||.
SYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIHDC-RQKGGKVLV

HCVAGFSRSATIAIAYLMIRRGMTAQEATRTV-----RKKR-P-IGPNEGFLKQLWLVAVA
|| || |||||..||||| ...|....| . |     ...| | | ||..|..|| .    
HCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase spur_DUSP3A.AA Subfamily.DSP3.PD 2-97 61 3.7e-48 154.5 In-house 50-145 (148) Show / Hide 
Range on Protein: 2-97
Range on HMM: 50-145/148
Sequence Identity: 61% (59 aa)

YQDTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEALEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRPIGPNEGFLKQLWLV
|.|..|||.|..|.||| ....|.|..|..||||||.|..||||.|||.|.|||||...||||||| .|..||..|||||| |.|||||||||. .
YkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkreilPneGflkqLlel
Phosphatase spur_DUSP3A.AA DSPc 2-94 38 5e-31 109.8 Pfam 37-145 (151) Show / Hide 
Range on Protein: 2-94
Range on HMM: 37-145/151
Sequence Identity: 38% (42 aa)

YQDTNIKYCGLP-VND---------VPGANMKKHFNTAVKFIDEALEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTV-----RKKR-P-I
| . .. | ..| |.|          ...|. ..|. |..||| . .|. ||||.|| || ||||...||||| .|.|...|| . |     ...| | |
YHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDC-RQKGGKVLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMI

GPNEGFLKQL
.|| .|..||
SPNMNFWRQL
Phosphatase spur_DUSP3A.AA Subfamily.DSP19.PD 6-95 41 5.1e-30 95.5 In-house 45-134 (139) Show / Hide 
Range on Protein: 6-95
Range on HMM: 45-134/139
Sequence Identity: 41% (37 aa)

NIKYCGLPVNDVPGANMKKHFNTAVKFIDEALEQEdGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKR-PIGPNEGFLKQLW
...|. ... |.| ... .....|..||.||.... | ||.|| || ||||...||||| .. .. ..| ..||..| .| |||||.||| 
dftyksieilDlpetkllsylkealdFieearskd-grvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpcikPneGFikqLk
Phosphatase spur_DUSP3A.AA Family.DSP.PD 4-94 46 3.5e-29 93.6 In-house 149-240 (387) Show / Hide 
Range on Protein: 4-94
Range on HMM: 149-240/387
Sequence Identity: 46% (43 aa)

DTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEALEQeDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP--IGPNEGFLKQL
. .|||. .|. | .  .. ..|  |..||.|. ..  |.||.|| || .||.|. ||||| ..|.|..|| . ||.|||  | ||.||||||
elgikylripidDhnapplenlfekaidfieegnds-kgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskRpgvitpnqgflkql
Phosphatase spur_DUSP3A.AA Subfamily.DSP10.PD 4-94 42 4.5e-28 89.2 In-house 45-135 (141) Show / Hide 
Range on Protein: 4-94
Range on HMM: 45-135/141
Sequence Identity: 42% (39 aa)

DTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEAlEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP-IGPNEGFLKQL
.  ..|  .||.| .  |.|..|. |..||.||  .....||.|| || |||||..|||.|   ... .|| . |..||| | || .|. ||
kglvrykripvsdsgkqnlkqkfeealefieea-rkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekrPiisPnlnfmGql
Phosphatase spur_DUSP3A.AA Subfamily.DSP1.PD 4-94 42 7.9e-28 88.6 In-house 43-133 (139) Show / Hide 
Range on Protein: 4-94
Range on HMM: 43-133/139
Sequence Identity: 42% (39 aa)

DTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEAlEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP-IGPNEGFLKQL
..  ||  .||.| . |.....|..|..|||.. ....|.||.|| || |||||| .|||| .. .. .||   |...|  | || ||..||
eelfkyksipvednkkadisslfeeaidfidsv-kkkgGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrrsiisPnfgfvgqL
Phosphatase spur_DUSP3A.AA Subfamily.DSP12.PD 11-96 45 8.7e-28 88.5 In-house 52-137 (143) Show / Hide 
Range on Protein: 11-96
Range on HMM: 52-137/143
Sequence Identity: 45% (39 aa)

GLPVNDVPGANMKKHFNTAVKFIDEALeQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKK-RPIGPNEGFLKQLWL
... | | ... .|...||.||.|.| ...|.||.|| || |||.|| ||||| ....  ..|...|..| . | ||||||.|| | 
liqilDepeedlLshldeavrFieegl-ekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkkeiepNegFleQLkl
Phosphatase spur_DUSP3A.AA Subfamily.DSP6.PD 4-94 41 1.7e-26 83.9 In-house 45-135 (141) Show / Hide 
Range on Protein: 4-94
Range on HMM: 45-135/141
Sequence Identity: 41% (38 aa)

DTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEALEQeDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKR-PIGPNEGFLKQL
. ..||  .|..|.  .|. |.|  |..||||| .. . |||.|| || ||| |...|||| .. .. ..|   |.||.  | ||  |..||
sgelkykqipiedhlsqnlakffPeaiefidearsk-kskvlvhclaGvsrsvtvtlaylmkklalslndaydlvkkkksnisPnfnfmgql
Phosphatase spur_DUSP3A.AA Subfamily.DSP14.PD 5-94 41 7.9e-26 82.1 In-house 43-132 (138) Show / Hide 
Range on Protein: 5-94
Range on HMM: 43-132/138
Sequence Identity: 41% (38 aa)

TNIKYCGLPVNDVPGANMKKHFNTAVKFIDEaLEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP-IGPNEGFLKQL
...|.  ..|.| | |....||..... |.| .....||.|.||||| ||||....||||  . .. .|| ..|...|| | || || |||
edvktvkikveDkpeaklaehfdevadkiee-vkkkgGktlvhCvaGvsRsAslvlaylmkyeklsLreayklvksaRpiirPnvGFwkql
Phosphatase spur_DUSP3A.AA Subfamily.DSP8.PD 6-94 46 5.2e-24 76.2 In-house 47-135 (143) Show / Hide 
Range on Protein: 6-94
Range on HMM: 47-135/143
Sequence Identity: 46% (42 aa)

NIKYCGLPVNDVPGANMKKHFNTAVKFIDEAlEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP-IGPNEGFLKQL
. ..  .||.|    ..  .|..|..||| | ....||||.|| || |||||.||||.| .  |. .|| | |..||| | ||  || ||
esrflriPvkDkyeekllpwfdkalefidka-rsangkvlvhclaGisrsatvaiayimktlemsldeayrfvkekrptispnlnflgqL
Phosphatase spur_DUSP3A.AA Subfamily.LRR-DSP.PD 7-94 50 5.6e-24 75.9 In-house 45-131 (137) Show / Hide 
Range on Protein: 7-94
Range on HMM: 45-131/137
Sequence Identity: 50% (45 aa)

IKYCGLPVNDVPGANMKKHFNTAVKFIDEAleQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP-IGPNEGFLKQL
.||  . ..||. |.. .||.    ||||   .|.| ||||| || |||||..||||| .. .. .||   | |||| | ||.|||.||
fkyliidiedvdeadiyqhfkemnafideg--rekggvlihcragvsrsatlviaylmkknslkfkealdlvikkrpriypnrgfldql
Phosphatase spur_DUSP3A.AA Subfamily.DSP15.PD 6-94 36 1.1e-23 75.1 In-house 44-132 (138) Show / Hide 
Range on Protein: 6-94
Range on HMM: 44-132/138
Sequence Identity: 36% (33 aa)

NIKYCGLPVNDVPGANMKKHFNTAVKFIDEAlEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRPI-GPNEGFLKQL
.|||  ....| |  ...|.|. ...|| ..   |.|.||.||.|| ||| |...||.|    .. ..| ..|.  |.. .|| || .||
dikylcikaadsPdqdlskffkesidfihkc-rleggnvlvhclaGisrsvtlvvayimtvtelswedalkavkaarsvanPnvGfrrql
Phosphatase spur_DUSP3A.AA Subfamily.Slingshot.PD 2-94 41 1.3e-22 71.4 In-house 41-133 (139) Show / Hide 
Range on Protein: 2-94
Range on HMM: 41-133/139
Sequence Identity: 41% (39 aa)

YQDTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEALEqEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRPI-GPNEGFLKQL
. . ..||. . | | . ... ||.|.. |||..| | .. |||.||  | ||||.. ||| | . ... .|| . |...| |  ||.||||||
ffpekfkylnirvydeeetdllkhwnetykfiekake-kgskvlvhckmGvsrsastviayamkeyelsleealeyvkerrsiikpnkgflkql
Phosphatase spur_DUSP3A.AA Subfamily.STYX.PD 6-95 43 1.1e-19 62.1 In-house 52-141 (146) Show / Hide 
Range on Protein: 6-95
Range on HMM: 52-141/146
Sequence Identity: 43% (39 aa)

NIKYCGLPVNDVPGANMKKHFNTAVKFIDEALeQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKR-PIGPNEGFLKQLW
...|  | | | .  |. ... |. .|||..| |. ||||.|  || ||||.. |||.|   |.  .|| . |...|  | ||||| .|| 
rfrylvldvadntveniirylptvkefiddsl-qkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlk
Phosphatase spur_DUSP3A.AA Subfamily.PTPMT1.PD 1-83 30 2e-19 61.2 In-house 47-128 (146) Show / Hide 
Range on Protein: 1-83
Range on HMM: 47-128/146
Sequence Identity: 30% (25 aa)

EYQDTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEALEQEDgKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP
|.... ...  |.. |. .|  ... . .|.||..  .... .| .|| || .||||....||| .. ....||.....||||
ewkklGveqlqlatvDfteapslekleegvefiekvaskgs-svYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRp
Phosphatase spur_DUSP3A.AA Subfamily.STYXL1.PD 10-94 32 6.5e-18 56.6 In-house 53-137 (143) Show / Hide 
Range on Protein: 10-94
Range on HMM: 53-137/143
Sequence Identity: 32% (27 aa)

CGLPVNDVPGANMKKHFNTAVKFIDEALEqEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKR-PIGPNEGFLKQL
..|.|.. |.. .... .|.||..  . |.  ||.    | ||||...|||||  . .| ..|   ..| .  . || .|..||  
lhiavedeneadllerlkevvqfiekhkk-egevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkckenvkPnrafveql
Phosphatase spur_DUSP3A.AA Subfamily.PTPDC1.PD 2-83 32 1.8e-15 48.3 In-house 130-208 (229) Show / Hide 
Range on Protein: 2-83
Range on HMM: 130-208/229
Sequence Identity: 32% (27 aa)

YQDTNIKYCGLPVNDVPGANMKKHFnTAVKFIDEALeqEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP
.. ..| ..  . .|   | ...   . || .| ||  |.||. .|| ||  |   .  .||.  . .||.|| ..||.|||
lmrqgiyfynfglkDygvasleriL-divkvvdfal--eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp
Phosphatase spur_DUSP3A.AA Subfamily.DSP23.PD 27-83 31 3.2e-12 38.0 In-house 53-108 (128) Show / Hide 
Range on Protein: 27-83
Range on HMM: 53-108/128
Sequence Identity: 31% (18 aa)

NTAVKFIDEALEQeDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP
.  |. ..|| .. .. | .||. |. |. |.   ||.  .|..|..|   |||.|.
arlvriveeaekk-eeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrk
Phosphatase spur_DUSP3A.AA Subfamily.CDC14.PD 32-92 34 1.3e-10 32.7 In-house 190-252 (258) Show / Hide 
Range on Protein: 32-92
Range on HMM: 190-252/258
Sequence Identity: 34% (22 aa)

FIdEALEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRP---IGPNEGFLK
|. |..|. .|.. .|| ||  | .|.  .||... ..||.|.   .|  ||   ||| . .|.
fl-eitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtylv
Phosphatase spur_DUSP3A.AA Subfamily.PRL.PD 26-87 29 1e-09 29.7 In-house 65-126 (140) Show / Hide 
Range on Protein: 26-87
Range on HMM: 65-126/140
Sequence Identity: 29% (18 aa)

FNTAVKFIDEALEQ-EDGKVLIHCVAGFSRsATIAIAYLMIRRGMTAQEATRTVRKKRPIGPN
.  .. . |. .. ..  | .|||||. | | . .|  .|  ||. ..|   .|.||    | 
vdeWlellkekfkeepkstvavhcvaGlGr-aPvlvalalieaGmkyedavefirekrrgain
Phosphatase spur_DUSP3A.AA Subfamily.Laforin.PD 2-84 26 4.9e-08 24.1 In-house 66-147 (165) Show / Hide 
Range on Protein: 2-84
Range on HMM: 66-147/165
Sequence Identity: 26% (22 aa)

YQDTNIKYCGLPVNDVPGANMKKHFNTAVKFIDEALEqEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRPI
|..  . |  ||..|.   .  . .  || ..   || .  .| .|| ||  ||..|   .|.   | . .     .  |||.
ykeeglayiwlptedlstesrvenlpqavyllhalle-kghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpv
Phosphatase spur_DUSP3A.AA Subfamily.DSP11.PD 3-82 28 5.1e-08 24.2 In-house 41-122 (141) Show / Hide 
Range on Protein: 3-82
Range on HMM: 41-122/141
Sequence Identity: 28% (23 aa)

QDTNIKYCGL--PVNDVPGANMKKHFNTAVKFIDEALEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKR
.|...||  |  | ..||  .. |.|..|||   |  ...|  . .||  |  |.  .   ||. . |. ...| ..  . |
tdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeear
Phosphatase spur_DUSP3A.AA Subfamily.R_Nematode_3.PD 20-71 30 8e-08 23.3 In-house 178-228 (267) Show / Hide 
Range on Protein: 20-71
Range on HMM: 178-228/267
Sequence Identity: 30% (15 aa)

ANMKKHFNTAVKFIDEaLEQEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTA
|.... ..|.. |.  .|.    |..||..| |||||.| . | .   ..  
lnapeepkealelikf-veksktpvvVHCsdGisRsatlaaielgyqliiks
Phosphatase spur_DUSP3A.AA Subfamily.PTEN.PD 28-82 28 3.3e-07 21.3 In-house 80-136 (305) Show / Hide 
Range on Protein: 28-82
Range on HMM: 80-136/305
Sequence Identity: 28% (16 aa)

TAVKFIDEALEQEDGKV-LIHCVAGFSRSATIAIAYLMIRRGMTAQ-EATRTVRKKR
. |. .|. |.... .|  .|| ||  |. ..  |||. .  .. . || .   .||
eivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR
Phosphatase spur_DUSP3A.AA Subfamily.RNGTT.PD 23-93 28 1.2e-06 19.5 In-house 60-132 (140) Show / Hide 
Range on Protein: 23-93
Range on HMM: 60-132/140
Sequence Identity: 28% (21 aa)

KKHFNTAVKFIDEALE-QEDGKVLIHCVAGFSRSATIAIAYLMIRRGMTAQEATRTVRKKRPIGP-NEGFLKQ
|.. .. .| ..| |. . |  . .||  || |   . .|||. .  .. ..|  .  | || |   |..||.
keqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiykedylke
Phosphatase spur_DUSP3A.AA Subfamily.RK.PD 7-65 26 3.1e-06 17.9 In-house 165-223 (267) Show / Hide 
Range on Protein: 7-65
Range on HMM: 165-223/267
Sequence Identity: 26% (16 aa)

IKYCGLPVN-DVPgaNMKKHFNTAVKFIDEALEQ-EDGKVLIHCVAGFSRSATIAIAYLMI
... | |   |||  . |. . . .. ...  |. |.|....||.||  || |  .   ..
fqflgWpeyrdvP--vskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiaidivl
Phosphatase spur_DUSP3A.AA Subfamily.N12.PD 7-70 31 7.5e-06 16.6 In-house 167-227 (270) Show / Hide 
Range on Protein: 7-70
Range on HMM: 167-227/270
Sequence Identity: 31% (20 aa)

IKYCGLPVNDVPGAnmKKHFNTAVKFIDEALEQEDGKVLIHCVAGFSRSATI-AIAYlmIRRGMT
..|   |  .|| .  .|.    .. . |  |.||  ...|| ||  |  || || |  .|. . 
fhytaWPDhgvPss--aksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidy--vrellk
Sequence
Name Sequence Type Origin Length Description Download
spur_DUSP3A.AA Protein None 174 None Fasta, JSON
spur_DUSP3A.NA RNA None 522 None Fasta, JSON
spur_DUSP3A.AA.PD_1-101 Protein Phosphatase Domain None 101 None Fasta, JSON