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Gene spur_RNGTT

spur_RNGTT
Species: S.purpuratus
Alias: spur_RNGTT
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: RNGTT
Protein domain

Protein domains of spur_RNGTT.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase spur_RNGTT.AA Subfamily.DSP11.PD 39-172 38 1.4e-36 115.5 In-house 2-137 (141) Show / Hide 
Range on Protein: 39-172
Range on HMM: 2-137/141
Sequence Identity: 38% (53 aa)

EENRFDTSMLFAYMNSRQVKLGWVFDLTNTNRFYDKDEIEKNGARHIKLPCRGRgECPSKEQTSLFIQMCST---NCKNPDQIIGVHCTHGYNRTGFLIC
||.|| .. |.  ..... ||| | |||||.|.|.|.|....| .. || | |. | |.||. . |... .    ..|. |..||||||||||||.||| 
eeerfapedlleklqeknkklGLvidltntdryykkkeltdegvkykklncpGh-evpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliC

AYLVETLDWSVDAAVSLFAQGRPPGIYKGDYIQELFD
||... ..| . |.. | . |   . . .|...| . 
rylidvegyspedaieafeearGhslerenyledLkk
MRNA_cap_enzyme spur_RNGTT.AA mRNA_cap_enzyme 261-447 39 1.2e-111 267.21 Pfam 1-213 (213) Show / Hide 
Range on Protein: 261-447
Range on HMM: 1-213/213
Sequence Identity: 39% (84 aa)

QPVSMDR-NNINFLKKNYYWVSWKADGIRYMMLIDGP---GE---VYLFDRDHVVFSAPHLSFPNRK--GP------HRDTLVDGEMIIDTVDG----KS
|||||.| .|..|||.||| |.||.||.||||.|..    ||   .|..|||. ..  . . ||...   .      | .||.||||.|||. .    . 
QPVSMSRRENMKFLKQNYYYVCWKTDGMRYMMFITDHPEYGEFKGCYMIDRDMNYYHVENMRFPCKYNKWGESLDKHHHYTLLDGEMCIDTIPMQETQCQ

VARYLIYDIIKYWGKP-VGGCDFG--WRRRCIQDEIIAPREVE--LQKGSIDRMREPFGIREKPFWDITSSKKIL--DGSFSQELMHETDGLIFQPHKDP
. ||||||.... |.. |  ..|    |  .|  ||| || ..  .  . ..   .|| .| |..||.  |.|..  . .| ..| ||.||||||. ..|
QPRYLIYDCVAINGQCRVMQWPFYSRKRWEMIKREIIKPRNHNMKFKTHWYRYDMFPFSVRFKDMWDNWHSEKLVYYFHKFIPHLCHEIDGLIFQCWDTP

YIPGRCDLILKWK
|.||||. ..|||
YVPGRCQNLFKWK
Phosphatase spur_RNGTT.AA Subfamily.RNGTT.PD 40-177 63 3.7e-70 224.2 In-house 2-140 (140) Show / Hide 
Range on Protein: 40-177
Range on HMM: 2-140/140
Sequence Identity: 63% (88 aa)

ENRFDTSMLFAYMNSRQVKLGWVFDLTNTNRFYDKDEIEKNGARHIKLPCRGRGECPSKEQTSLFIQMCST-NCKNPDQIIGVHCTHGYNRTGFLICAYL
|..|...||..|.....||||.|.|||||.|.|||.|.||.|...||| ||||||.|.||||.|||..... ..|.||..||||||||.|||||||.|||
eeafepemlksylktlkvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayL

VETLDWSVDAAVSLFAQGRPPGIYKGDYIQELFDRYGDV
||..||||.|||.|||. ||||||| ||..|||.||.|.
vekedwsveaavalfakarppGiykedylkelfkryedl
Phosphatase spur_RNGTT.AA Family.DSP.PD 61-173 23 1.2e-17 54.4 In-house 135-243 (387) Show / Hide 
Range on Protein: 61-173
Range on HMM: 135-243/387
Sequence Identity: 23% (27 aa)

WVFDLTntnrfYDKDEIEK-NGARHIKLPCRGRgECPSKEQTslFIQMCSTNCK--NPDQIIGVHCTHGYNRTGFLICAYLVETLDWSVDAAVSLFAQGR
. .||     .||....| .| .....|.    ..|. |.   |.. .   ..  .. . . |||..| .|.| ||.|||..  ... ..|. .... ||
kivnlt-----ddkpqftkelgikylripidDh-napplenl--fekaidfieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskR

PpGIYKG--DYIQELFDR
 |. .    ....|.|  
p-gvitpnqgflkqlkdl
Phosphatase spur_RNGTT.AA Subfamily.CDC14.PD 62-158 25 5.3e-11 32.7 In-house 151-240 (258) Show / Hide 
Range on Protein: 62-158
Range on HMM: 151-240/258
Sequence Identity: 25% (24 aa)

VFDLTntNRFYDKDEIEKNGARHIKLPCRgRGECPSKEQTSLFIQMCSTNcknpDQIIGVHCTHGYNRTGFLICAYLVETLDWSVDAAVSLFAQGRP
.  |   .. ||. . ...|  |  |     | .||..    |.... .     .  | |||  |  ||| || .||. .   . . ....   || 
ivrLn--kklYdakkftdaGfahlDlffi-DGtvPsdailkkfleiteka----eGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarP
Phosphatase spur_RNGTT.AA Subfamily.DSP23.PD 95-159 28 4.1e-10 29.9 In-house 46-109 (128) Show / Hide 
Range on Protein: 95-159
Range on HMM: 46-109/128
Sequence Identity: 28% (18 aa)

CPSKEQTSLFIQMCSTNcKNPDQIIGVHCTHGYNRTGFLICAYLVETLDWSVDAAVSLFAQGRPP
|. || . .....    .. .. .||||  |. ||| |.  |||.. . . | |.    . |.  
PPaleqvarlvriveea-ekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkG
Phosphatase spur_RNGTT.AA Subfamily.PTPDC1.PD 104-167 28 6.3e-10 28.9 In-house 156-217 (229) Show / Hide 
Range on Protein: 104-167
Range on HMM: 156-217/229
Sequence Identity: 28% (18 aa)

FIQMCSTNCKNpdQIIGVHCTHGYNRTGFLICAYLVETLDWSVDAAVSLFAQGRPPGIYKGDYI
... .  ...    |.|||  |  ||| ||..||| . . . . |..|  . ||  |.  . . 
ivkvvdfalee--gkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqv
Phosphatase spur_RNGTT.AA Subfamily.PTPMT1.PD 74-158 24 2e-09 27.5 In-house 45-128 (146) Show / Hide 
Range on Protein: 74-158
Range on HMM: 45-128/146
Sequence Identity: 24% (21 aa)

KDEIEKNGARHIKLPCRGRGECPSKEQTSLFIQMCSTNCKNpDQIIGVHCTHGYNRTGFLICAYLVETLDWSVDAAVSLFAQGRP
..| .|.| ....|.    .| ||.|. .  ... ..  ..  . . |||  |  | . |. .||...  .| . ||..... ||
teewkklGveqlqlatvDfteapslekleegvefiekvask-gssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRp
Phosphatase spur_RNGTT.AA Subfamily.PTEN.PD 114-157 33 1.4e-08 24.5 In-house 92-136 (305) Show / Hide 
Range on Protein: 114-157
Range on HMM: 92-136/305
Sequence Identity: 33% (15 aa)

NPDQIIGVHCTHGYNRTGFLICAYLVETLDWS-VDAAVSLFAQGR
. .... |||  |  ||| .|||||....  .  | |...... |
dksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR
Phosphatase spur_RNGTT.AA Subfamily.PRL.PD 69-152 22 4.2e-08 23.2 In-house 34-116 (140) Show / Hide 
Range on Protein: 69-152
Range on HMM: 34-116/140
Sequence Identity: 22% (19 aa)

NRFYDKDEIEKNGARHIKLPCRgRGECPSKEQTSLFIQMCSTN-CKNPDQIIGVHCTHGYNRTGFLICAYLVETlDWSVDAAVSL
.  || ......| . . |.    |  |.||    ..... .. ...|.....|||  |  |.  |..  |.|.   . . ||..
epsydaeklkeegievldlafd-dGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea-Gmkyedavef
Phosphatase spur_RNGTT.AA Subfamily.DSP12.PD 100-157 22 1e-07 22.3 In-house 69-122 (143) Show / Hide 
Range on Protein: 100-157
Range on HMM: 69-122/143
Sequence Identity: 22% (13 aa)

QTSLFIQMCStnckNPDQIIGVHCTHGYNRTGFLICAYLVETLDWSVDAAVSLFAQGR
..  ||. .     . .. . |||. |  |   .. |||. . ..|.. |..|  . .
eavrFieegl----ekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekk
Phosphatase spur_RNGTT.AA DSPc 119-158 30 5.1e-07 26.33 Pfam 88-133 (151) Show / Hide 
Range on Protein: 119-158
Range on HMM: 88-133/151
Sequence Identity: 30% (14 aa)

IGVHCTHGYNRTGFLICAYLVETLDWSVDAAVSLF-----AQGR-P
. |||..|..|.. |..|||  .  .|.. | ...      | | |
VLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCP
Phosphatase spur_RNGTT.AA Subfamily.TPIP.PD 113-141 34 1.1e-06 18.5 In-house 34-62 (245) Show / Hide 
Range on Protein: 113-141
Range on HMM: 34-62/245
Sequence Identity: 34% (10 aa)

KNPDQIIGVHCTHGYNRTGFLICAYLVET
|...... .||  | .||| ..||.|...
kdlenvvaihckGGkgrtGtivcallias
MRNA_cap_C spur_RNGTT.AA mRNA_cap_C 450-548 32 1e-37 135.33 Pfam 1-138 (138) Show / Hide 
Range on Protein: 450-548
Range on HMM: 1-138/138
Sequence Identity: 32% (45 aa)

SLNSVDFRIKVTVVK---REGCI---PETLGLL-FV-----------GGQQQPF---------------GQMKITKDLKQYDNKIIECSY--NN--KKG-
..|.|||..|..  .    .|     ... |.| ..           ||   ||               . .| |.|.|.|.|||.||.   .|  |.  
EMNTVDFMLKMCFECIGGEDGMLDRFQQWRGYLDYMEMPNFQKGRWWGGYNCPFFCKMYVFNKMRIFDIEWEKWTNDEKPYNNKIVECTWLVDNKQKGRP

-WQFMRERTDKSFPNGYKTAVAVCQSIQNPVTKDFLMN
 | |||.|||||.||.. || .||.|| ..|||. | .
EWVFMRFRTDKSNPNHINTARKVCYSIEDNVTKEYLFE
Sequence
Name Sequence Type Origin Length Description Download
spur_RNGTT.AA Protein None 613 None Fasta, JSON
spur_RNGTT.NA RNA None 1839 None Fasta, JSON
spur_RNGTT.AA.PD_40-177 Protein Phosphatase Domain None 138 None Fasta, JSON