Gene spur_SSH
spur_SSH
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of spur_SSH.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Zf-DHHC | spur_SSH.AA | zf-DHHC | 108-162 | 61 | 5.4e-35 | 118.2 | Pfam | 1-55 (55) | Show / Hide |
Range on Protein: 108-162 Range on HMM: 1-55/55 Sequence Identity: 61% (34 aa) WCSTCRFYRPPRCSHCSVCNNCIERFDHHCPWVNNCVGRRNYRYFFLFLLSLTMH ||.||. ..|||| ||.||| |. |.||||||.|||.|.||.|||.|||..|.. WCKTCNIWKPPRCHHCRVCNRCVLRMDHHCPWINNCIGHRNHRYFILFLFWLCIY |
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DEK_C | spur_SSH.AA | DEK_C | 447-493 | 36 | 2.9e-09 | 34.03 | Pfam | 8-56 (56) | Show / Hide |
Range on Protein: 447-493 Range on HMM: 8-56/56 Sequence Identity: 36% (18 aa) KLKEIMIQCDLETVTSKMVRISLEKEI-GKELK-EYKRFIDKQILLICG ...||. . ||.|||.| .| ||.. | .|. ..| ||..||. . . EIREILRTADLMTVTMKQIRKQLEQRFPGCDLSKHRKAFIKEQIEEFLD |
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Phosphatase | spur_SSH.AA | DSPc | 497-635 | 29 | 4.8e-45 | 156.88 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 497-635 Range on HMM: 1-172/172 Sequence Identity: 29% (50 aa) SASKIFDHIYLGSEWNAS--DLDELEENGVGYILNITKECDN-----------------FFPERFKYCNIRLYDD--------VEEDLLNHWNTTYLFLS . |.| |.||||. .. ....|..... ...| |.||.. .. | |..| . || ......... .| |.. GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH KAKEAGSKALVHCKMGISRSASTVIAYAMKEYGMTLEYALDFV-----KGKR-SIIRPNDAFMKQLQVYEGI ... | | ||||..||||||. .||| || ..|... |..|| | .| .||.||. |..||...| . DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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Phosphatase | spur_SSH.AA | Subfamily.Slingshot.PD | 498-635 | 75 | 9.6e-76 | 242.6 | In-house | 2-139 (139) | Show / Hide |
Range on Protein: 498-635 Range on HMM: 2-139/139 Sequence Identity: 75% (104 aa) ASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYA |||||||.|||||||||.|.||.|||| ||||.|||.||||||.|||.|||.||. |.|||.|||.|| |..||||.|||.|||||||.||||||||||| askifdhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviaya MKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGI ||||...|| ||..|| .||||.||..|.|||.||||| mkeyelsleealeyvkerrsiikpnkgflkqlkvyegi |
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Phosphatase | spur_SSH.AA | Subfamily.DSP1.PD | 499-633 | 42 | 8.8e-43 | 136.0 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 499-633 Range on HMM: 3-137/139 Sequence Identity: 42% (58 aa) SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAM ..| |..||||. .||.|. |.| .. .||...|..| |.| ||| .| . |. ..|....... |. ..|..| . ||||..||||||. |.|| | veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE || ..|| | .||| .|||| || .|..|| .| kekkvrleeafefvkqrrsiisPnfgfvgqLlefe |
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Phosphatase | spur_SSH.AA | DSPc | 505-635 | 32 | 3.5e-40 | 141.63 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 505-635 Range on HMM: 1-151/151 Sequence Identity: 32% (49 aa) IYLGSEWNAS-DLDELEENGVGYILNITKECDN---FFPERFKYCNIR-LYD---------DVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSA .||||. .. |.. |...|. ...| |.||.| . ...| | .| . | .... .. . . |...... | | ||||..|||||| LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA STVIAYAMKEYGMTLEYALDFV-----KGKR-SIIRPNDAFMKQLQVYEGI . .||| || ..|... |.||| | .| ..|.||. |..||. || . CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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Phosphatase | spur_SSH.AA | Family.DSP.PD | 497-666 | 36 | 7.6e-40 | 127.7 | In-house | 106-277 (387) | Show / Hide |
Range on Protein: 497-666 Range on HMM: 106-277/387 Sequence Identity: 36% (62 aa) SASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFP-ERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIA |.|..|.|||| .|..|..|.|.|| |.|.|.....| . .||..| . | ...| |.. . |...........|||||.|..||...||| | kpseilphlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtliia YAMKEYGMTLEYALDFVKGKRS-IIRPNDAFMKQLQVYEGILEASRQRHTMFRSKSESSLSRSESVECLASV | .|.||| |||.|. ||. .|.||. |.|||. .| . ... ..| | |||. || YlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrfvissivqnlgsvevsvsv |
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Phosphatase | spur_SSH.AA | Subfamily.DSP19.PD | 499-633 | 39 | 1.9e-38 | 121.8 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 499-633 Range on HMM: 3-137/139 Sequence Identity: 39% (53 aa) SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAM ... ...|||| |.|...|..... .|||.. . .|.||. |.|..| ..|. |..||...... |. .|.... ||||. |.||||| |||| | aevkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylm KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE |. ..||.||. |. .| |.|| |.|||. || kdeelslekalekvrearpcikPneGFikqLkeye |
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Phosphatase | spur_SSH.AA | Subfamily.DSP10.PD | 498-633 | 42 | 2.4e-37 | 118.2 | In-house | 2-139 (141) | Show / Hide |
Range on Protein: 498-633 Range on HMM: 2-139/141 Sequence Identity: 42% (59 aa) ASKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPER--FKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIA ||.|. ...||.| .|.| | |. |. |.||.|... ||| |. ..| .| . | ...| .... .. |. .|.. ||. ||||. |||||| ||| assilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvia YAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE | || ...|. | ||| || || || || || .| yvmkhlslslseaykfvkekrPiisPnlnfmGqllefe |
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Phosphatase | spur_SSH.AA | Subfamily.DSP6.PD | 500-633 | 38 | 2.1e-36 | 115.1 | In-house | 4-139 (141) | Show / Hide |
Range on Protein: 500-633 Range on HMM: 4-139/141 Sequence Identity: 38% (52 aa) KIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPE--RFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYA .| ...||||. .||.|. |.. .. |.||.|.. .|.| | .|| .| . | ....| ... . |. .|... || |||| |.|||. ..|| | eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl MKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE |.. ..|. | |.|| |.| | || ||.|| .| mkklalslndaydlvkkkksnisPnfnfmgqlldfe |
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Phosphatase | spur_SSH.AA | Subfamily.DSP14.PD | 499-633 | 37 | 1.7e-34 | 109.1 | In-house | 3-136 (138) | Show / Hide |
Range on Protein: 499-633 Range on HMM: 3-136/138 Sequence Identity: 37% (51 aa) SKIFDHIYLGsEWNASDLDELEENGVGYILNITKECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAM |.| ...||. |.. ..|..... |.|.| | . | .|. .|.. |. |..| .|..... . ..|..| |.||||..|.||||| |.|| | seitesLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylm KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE | ..|. | .|| .|.||||| | |||. || kyeklsLreayklvksaRpiirPnvGFwkqlidyE |
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Phosphatase | spur_SSH.AA | Subfamily.DSP8.PD | 499-634 | 40 | 6.1e-34 | 107.4 | In-house | 3-140 (143) | Show / Hide |
Range on Protein: 499-634 Range on HMM: 3-140/143 Sequence Identity: 40% (55 aa) SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDN--FFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY .| ...||||. .. | . |...|..|.|||...|. . . .. | . |..||.||....... |. ||..| .| |||| ||||||. .||| trilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiay AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEG ||. |.|. | ||| ||. | || |. || || imktlemsldeayrfvkekrptispnlnflgqLleyek |
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Phosphatase | spur_SSH.AA | Subfamily.DSP12.PD | 499-634 | 36 | 1.8e-33 | 106.0 | In-house | 3-140 (143) | Show / Hide |
Range on Protein: 499-634 Range on HMM: 3-140/143 Sequence Identity: 36% (50 aa) SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECD-NFFPE-RFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAY |.| . .|||. .. . ..|.| . .| ..|| .. | |. .| ..|. |||||.| ... |.... | . . ||||..|.|||...|||| seilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAY AMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEG ||.... || ||..|| |.. |.||. |..||...| lmkkeklslekAlklvkekkkeiepNegFleQLklfek |
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Phosphatase | spur_SSH.AA | Subfamily.LRR-DSP.PD | 499-633 | 37 | 1.7e-31 | 99.2 | In-house | 3-135 (137) | Show / Hide |
Range on Protein: 499-633 Range on HMM: 3-135/137 Sequence Identity: 37% (50 aa) SKIFDHIYLGSEWNASDLDELEENGVGYILNITkECDNFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSkALVHCKMGISRSASTVIAYAM ..| |..|||. | . |..|.| .|| .. ... ..|. ||| | . | | |. .|.. . |. . .| | |.||. |.||||. |||| | dliidklylgcresamnksilkdnnvthilava-dfkplypdlfkyliidiedvdeadiyqhfkemnafidegrekgg-vlihcragvsrsatlviaylm KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE |. .... |||.|. ||. |.|| |..||. .| kknslkfkealdlvikkrpriypnrgfldqlkkfe |
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Phosphatase | spur_SSH.AA | Subfamily.DSP3.PD | 500-631 | 33 | 1.7e-27 | 86.5 | In-house | 4-144 (148) | Show / Hide |
Range on Protein: 500-631 Range on HMM: 4-144/148 Sequence Identity: 33% (46 aa) KIFDHIYLGSEWNASDLDELEENGVGYILNITKECD--------NFFPE-RFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEA-GSKALVHCKMGISRS .....|.| | |.| ..|.. |. ..|| .... .|. . ||. . | | || ..... |. .| . ..| ||||..|||||| evypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRs ASTVIAYAMKEYGMTLEYALDFVKGKRSIiRPNDAFMKQLQV |.|| | .||. |. |. ||.| ||. |.||| atlvlayLmirrkltlkeaiktvrkkrei-lPneGflkqLle |
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Phosphatase | spur_SSH.AA | Subfamily.STYX.PD | 501-635 | 34 | 1.6e-25 | 80.0 | In-house | 5-146 (146) | Show / Hide |
Range on Protein: 501-635 Range on HMM: 5-146/146 Sequence Identity: 34% (49 aa) IFDHIYLGSEW--NASDLDELEENGVGYILNITKECD-----NFFPERFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTV |. ..|| | |. |.|.|. .|. | .. . ||.||.| . . |.. |... . |. |. .. . | | ||| . ||||||. | ilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalv IAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYEGI ||| |. ||. | .|. .| | ||. |..||..|| | iayimetyglkyreafayvqerrfcinpnegfvsqlkeyeai |
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Phosphatase | spur_SSH.AA | Subfamily.DSP15.PD | 499-633 | 35 | 2.4e-25 | 79.4 | In-house | 3-136 (138) | Show / Hide |
Range on Protein: 499-633 Range on HMM: 3-136/138 Sequence Identity: 35% (48 aa) SKIFDHIYLGSEWNASDLDELEENGVGYILNITKECDNFFPErFKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAM .|. .|.|. .|.| . |||| . .|| | . . .... .|| |. | . || .... . |. |.. |.. |||| |||||. |.|| | nkvlpGlyvGnfrdakdkeqleenkithilsihdsakplled-ikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayim KEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE .. | || || ||. || | .||| .| tvtelswedalkavkaarsvanPnvGfrrqlqefe |
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Phosphatase | spur_SSH.AA | Subfamily.STYXL1.PD | 504-633 | 30 | 3.8e-18 | 56.4 | In-house | 9-141 (143) | Show / Hide |
Range on Protein: 504-633 Range on HMM: 9-141/143 Sequence Identity: 30% (40 aa) HIYLGSEWNASDLDELEENGVGYILNITKECDNFFPER---FKYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKE ..||| . .| . .. | .|......... | .|.. |. | |||.. . |. | |. |. || . ||||||. .||| | . klylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmys YGMTLEYALDFVKGKRSIIRPNDAFMKQLQVYE . .||. |....| .. ..|| ||..||. .| kkitlkkaykylkkckenvkPnrafveqlseWe |
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Phosphatase | spur_SSH.AA | Subfamily.PTPMT1.PD | 543-632 | 32 | 9.4e-15 | 45.0 | In-house | 54-143 (146) | Show / Hide |
Range on Protein: 543-632 Range on HMM: 54-143/146 Sequence Identity: 32% (29 aa) KYCNIRLYDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKRSIIRPNDAFMKQLQVY .. .. | .| |.. . . |..| .. ||. |||| | .|||. |..| ||.. .. | | .|.| ||..|| ... .. || . eqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqef |
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Phosphatase | spur_SSH.AA | Subfamily.CDC14.PD | 567-630 | 27 | 1.4e-08 | 25.0 | In-house | 190-255 (258) | Show / Hide |
Range on Protein: 567-630 Range on HMM: 190-255/258 Sequence Identity: 27% (18 aa) FLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKR--SIIRPNDAFMKQLQ ||. . .| .. |||| |. | .. . .| .|.|..| . .. ... | |.| | . .... | fleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtylvekq |
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Phosphatase | spur_SSH.AA | Subfamily.DSP23.PD | 519-616 | 20 | 2.7e-06 | 17.8 | In-house | 9-107 (128) | Show / Hide |
Range on Protein: 519-616 Range on HMM: 9-107/128 Sequence Identity: 20% (20 aa) LEENGVGYILNITKECDNFF--PERFKYCNIRLyDDVEEDLLNHWNTTYLFLSKAKEAGSKALVHCKMGISRSASTVIAYAMKEYGMTLEYALDFVKGKR | ..|. .....|.|. .. . . |.. .| |. . . . .|.. . ||| .|. |. . . | .|| |.. .|. |. .| ladqGirvlvslttegapyseaapsltlrridi-pdfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrr |
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Phosphatase | spur_SSH.AA | Subfamily.PRL.PD | 571-617 | 39 | 4.2e-06 | 16.9 | In-house | 77-122 (140) | Show / Hide |
Range on Protein: 571-617 Range on HMM: 77-122/140 Sequence Identity: 39% (18 aa) AKEAGSKALVHCKMGISRsASTVIAYAMKEYGMTLEYALDFVKGKRS ..| .| ||| |. | | ..| |. | ||. | |..|.. || keepkstvavhcvaGlGr-aPvlvalalieaGmkyedavefirekrr |
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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spur_SSH.AA | Protein | None | 1308 | None | Fasta, JSON |
spur_SSH.NA | RNA | None | 3924 | None | Fasta, JSON |
spur_SSH.AA.PD_497-635 | Protein Phosphatase Domain | None | 139 | None | Fasta, JSON |