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Gene Spur_hmm58538,hmm150697

Spur_hmm58538,hmm150697
Species: S.purpuratus
Alias: Spur_hmm58538,hmm150697
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Myotubularin
Subfamily: MTMR3
Protein domain

Protein domains of Spur_hmm58538,hmm150697.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Myotub-related Spur_hmm58538,hmm150697.AA Myotub-related 200-357 41 3.2e-53 187.93 Pfam 1-121 (121) Show / Hide 
Range on Protein: 200-357
Range on HMM: 1-121/121
Sequence Identity: 41% (65 aa)

FKYCTTYPTQHIVPKEIEDDAMKKSINFRTSKRFPSVVWRHKGNGAVIARCSQPAVGWLGWRSEEDERFMSAILDACAMDDPRKNKKSCHSNGYVKSEQY
.. |.|||   .|||.| ||. ||.  ||  .||| ..|||. |||||.||||| |||.|||. |||. . ||..|.| |                    
YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCKEDEKLVQAIMKANA-D--------------------

RVTDDQDEMRRGEYERSNQSKTILIIDARSYAAAFANRAKGGGCEYPEYYTCCDIEFM
                  ||. ..|.|||.|..|.||||||||.|  |.| .... ||
----------------MIQSRKMYIVDARPYTNAMANRAKGGGYENEEHYPNWEFVFM
Phosphatase Spur_hmm58538,hmm150697.AA Subfamily.MTMR1.PD 379-520 52 2.5e-58 186.9 In-house 8-149 (149) Show / Hide 
Range on Protein: 379-520
Range on HMM: 8-149/149
Sequence Identity: 52% (74 aa)

NSLDQTTWLSNLEATKWLQNLSMLLKAAIKVVTAVDQEARPVIVHCSDGWDRTPQIVALAEIMLDPYYRTMQGFQALVEREWLDFGHKFADRCGHRPGQD
|.|.. |||.||.||||. . ..|. |.... .|..|   |.||||||||||.|. .|| ..||.||||..||. |.|.||| ||||||.| ||   .  
psideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighgdknh

DANERCPVFLQWLDCIHQLLRQYPTAFEFNETFLVKLVQHTY
 ..| |||||..||. |. ||.||||||||.||. ...| | 
adadrspvflqfidcvwqvtrqfptafefneeflitildhly
Phosphatase Spur_hmm58538,hmm150697.AA Subfamily.MTMR3.PD 386-520 79 2.5e-82 264.3 In-house 1-135 (135) Show / Hide 
Range on Protein: 386-520
Range on HMM: 1-135/135
Sequence Identity: 79% (107 aa)

WLSNLEATKWLQNLSMLLKAAIKVVTAVDQEARPVIVHCSDGWDRTPQIVALAEIMLDPYYRTMQGFQALVEREWLDFGHKFADRCGHRPGQDDANERCP
.||.||.|||||.||.|||||.|||.|||.|.|||.|||||||||||||||||...|||||||..||..|||||||||||||||||||...||.||||||
flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp

VFLQWLDCIHQLLRQYPTAFEFNETFLVKLVQHTY
|||||||.||| .|.||.|||||.|||||||||| 
vflqwldcvhqlkkqfptsfefneaflvklvqhty
Phosphatase Spur_hmm58538,hmm150697.AA Family.Myotubularin.PD 382-520 57 5.8e-69 221.1 In-house 3-141 (141) Show / Hide 
Range on Protein: 382-520
Range on HMM: 3-141/141
Sequence Identity: 57% (80 aa)

DQTTWLSNLEATKWLQNLSMLLKAAIKVVTAVDQEARPVIVHCSDGWDRTPQIVALAEIMLDPYYRTMQGFQALVEREWLDFGHKFADRCGHRPGQDDAN
....|||.||.||||.....|||||.|.|..|..|...|.||||||||||.|...||...|||||||..||. |.|.|||.||||||.|.||.  ... .
eekkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdksesee

ERCPVFLQWLDCIHQLLRQYPTAFEFNETFLVKLVQHTY
||.|||||..||..|| .|.||||||||.||.|...|.|
ersPvflqfidcvyqltkqfptafefnesflikildhly
Phosphatase Spur_hmm58538,hmm150697.AA Subfamily.C2-MTMR1.PD 384-519 50 5e-53 169.7 In-house 4-136 (137) Show / Hide 
Range on Protein: 384-519
Range on HMM: 4-136/137
Sequence Identity: 50% (67 aa)

TTWLSNLEATKWLQNLSMLLKAAIKVVTAVDQEARPVIVHCSDGWDRTPQIVALAEIMLDPYYRTMQGFQALVEREWLDFGHKFADRCGHrpgQDDANER
|||.||.|.||  .. .||||  .   |.. |   .|||||||||| |.|.||...|||||||..|.. |.|.||| ||||| .||.    | . || |.
vqwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlgg---adsvser

CPVFLQWLDCIHQLLRQYPTAFEFNETFLVKLVQHT
|||.|||..|. .|.|.|||..  .|.|| ...   
spiflqfldclyqvtkqfpsafeytarlllkladys
FYVE Spur_hmm58538,hmm150697.AA FYVE 1085-1154 35 2.7e-30 107.9 SMART 1-81 (81) Show / Hide 
Range on Protein: 1085-1154
Range on HMM: 1-81/81
Sequence Identity: 35% (29 aa)

TSRTLWIPDHAVSHC-SLCNSRFNL-VVRKHHCRNCGQIFCATCSNFFIAIPREQLYQ---------PQRVCQPCHQRLEV
 ... |.||. |.|| . |.  ||.  .|.||||.||.|||. |.|. | .|  . |.         | ||| .|....  
ETKPHWQPDEEVDHCCMNCRKEFNFVTNRRHHCRHCGRIFCSKCCNKWIPLPYMGNYKKNGNNQNFTPVRVCDDCYEMMHH
Phosphatase Spur_hmm58538,hmm150697.AA Subfamily.N_Nematode_1.PD 404-441 43 9e-07 19.0 In-house 183-220 (265) Show / Hide 
Range on Protein: 404-441
Range on HMM: 183-220/265
Sequence Identity: 43% (16 aa)

KAAIKVVTAVDQEARPVIVHCSDGWDRTPQIVALAEIM
||.....|| ..  |..|||| |  ||  |||.. |. 
laalelleavrgskgPivvhCsaGiGrtGtivaieyil
Phosphatase Spur_hmm58538,hmm150697.AA Subfamily.N_Choan_2.PD 398-441 31 1.9e-06 17.8 In-house 180-222 (266) Show / Hide 
Range on Protein: 398-441
Range on HMM: 180-222/266
Sequence Identity: 31% (14 aa)

NLSMLLKAAIKVVTAVDQEArPVIVHCSDGWDRTPQIVALAEIM
.|  .|.|  .| . .|..  |..||||.| .||  ..|.  ..
qllkmlravrrvrkeldkae-PllvHcsaGvgRtGtliaiDiav
Phosphatase Spur_hmm58538,hmm150697.AA Subfamily.N_Nematode_6.PD 404-443 35 2.3e-06 17.8 In-house 172-210 (253) Show / Hide 
Range on Protein: 404-443
Range on HMM: 172-210/253
Sequence Identity: 35% (14 aa)

KAAIKVVTAVDQEARPVIVHCSDGWDRTPQiVALAEIMLD
..|......| .. .|..|||| |  ||   .|| .|.|.
lsalrllsvvkkdkkPivvhCsaGvGrtGt-laliliile
FYVE Spur_hmm58538,hmm150697.AA FYVE 1088-1154 37 2.1e-31 110.23 Pfam 1-71 (71) Show / Hide 
Range on Protein: 1088-1154
Range on HMM: 1-71/71
Sequence Identity: 37% (27 aa)

TLWIPDHAVSHCSLCNSRFNLV-VRKHHCRNCGQIFC--ATCSNFFIAI--PREQLYQPQRVCQPCHQRLEV
. |.||..|.||. |...|..  .|.||||.||.|||  . ||.... .  |... ..|.|||. |.. |. 
PHWQPDSEVTHCMICQKPFTFFGRRRHHCRHCGRIFCDDSKCSSHKCIPHPPYYGWNKPVRVCD-CYDDLQK
Sequence
Name Sequence Type Origin Length Description Download
Spur_hmm58538,hmm150697.AA Protein None 1175 None Fasta, JSON
Spur_hmm58538,hmm150697.NA RNA None 3525 None Fasta, JSON
Spur_hmm58538,hmm150697.AA.PD_384-520 Protein Phosphatase Domain None 137 None Fasta, JSON