Gene Spur_hmm73208
Spur_hmm73208
Species: S.purpuratus
Alias: Spur_hmm73208
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Spur_hmm73208.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| UDENN | Spur_hmm73208.AA | uDENN | 82-120 | 33 | 1.6e-10 | 40.08 | Pfam | 54-95 (95) | Show / Hide |
Range on Protein: 82-120 Range on HMM: 54-95/95 Sequence Identity: 33% (14 aa) FCQPAGWRITSKA---QPPTYHVSVLTDIEARRHYCAVLTFS ||.| ||.. . ..|.... ||||.. |.|.. .||. FCFPDGWDWVTWRDRHYDPQFFSFVLTDEDGSRWYGFCRTFY |
|||||||||
| DENN | Spur_hmm73208.AA | DENN | 149-332 | 32 | 1.2e-78 | 272.07 | Pfam | 1-207 (207) | Show / Hide |
Range on Protein: 149-332 Range on HMM: 1-207/207 Sequence Identity: 32% (67 aa) FAPKCLALISRLEYFETL-KNCLGLMYTVYVDNV-------------EVEMETLVGNILGHVQVPPPGGPQVRFS---IGAGDRQALQPPL-SDSL-PV- ..|||. .|||. .|.|. ...|. .|..|... ....|... |.. .|..||||..|| || .|..... .| |. ...| || WIPKCYCIISRWPWFNTFWRKWLDCIYRRYTSCPHPRIPPSSPRVGMWNPIERYIQNLCYEVPFPPPGRTQVLFSFIPLGVYEPILFQRPSPDSELHPVW SRSSVALLVQQLGIHNIITLFCAAVTDQKIMFHCRSYTRLTEACGALISLLFPLKYSYVYIPVLPAALIEVLSTPTPFIMGIHSALKE---EATELLDVI . ... .| ..||. |...|||...| ..| || ..| .|| .| |. .||.|......|||..||.|...|..|.|||||.|| . . . ....||. EHIDFHPLFRCLGPENCLHLFCCVLTEHRIIFHSSHYAMLTLCCHAVVALLYPFQWQHIYIPICPARLLDYLCAPCPFIMGVHSRYFDSKLLYDPPDDVV VADLDGG ..|||.. CVDLDTN |
|||||||||
| SBF2 | Spur_hmm73208.AA | SBF2 | 457-707 | 42 | 1.2e-106 | 358.31 | Pfam | 1-233 (233) | Show / Hide |
Range on Protein: 457-707 Range on HMM: 1-233/233 Sequence Identity: 42% (110 aa) QIVPYNA-----SIGNFEGHRNLVNNSA---RRLEVLRTCINFIFENKILDARRLFPAVMRSLKSRVARQALLHELELHVNKNRA-MLEPQQFSMVVRLI ..|. . |.. .|.|.....||| |||||||.||..||.||||.|. .||||.|.||.|.||..| .||.||. ||. .|. ||| ||||.. PMGPPVNTIVPGSMSIMEKHSGMFHNSALMLRRLEVLRNCISYIFDNKILEAKKMFPAVLRALKGRAARICLCRELNLHCQQNRHFVLDHQQFDMVVRMM NAALQEDSHSEEFSLSMDFLPLISAFCRKLCPGIIQFAYTVTQDHPVFASHAFWETAFYADVEKNIQSLYVTPDNTPTYEKKDVSQSFNDAFAAAPDASG |.|||... ..| ||| .|||||||||..|||||. ||||| .. |||..|| || . | .|| .. NCALQDCCSMDEYGVAAALLPLSTAFCRKLCPGVHQFAYTCVQDHPVWKNQQFWEACFYQDVQNHIRELYL---------------------------NM SSASSAAANGLITSAERSPLDIAAEQLRLQPNMNHDAREEAKSNEESIVYSQAVHYANRM .. . .. .. ..|.. ..|||||.|| | | . .| ..||| ||||| |||||| HHDEQKTWSDWCHKQEPCAMEIAAEQMRLWPTMDKEKQQELVQKEESTVYSQAIHYANRM |
|||||||||
| DENN | Spur_hmm73208.AA | DENN | 149-332 | 28 | 2.9e-70 | 240.64 | SMART | 1-204 (204) | Show / Hide |
Range on Protein: 149-332 Range on HMM: 1-204/204 Sequence Identity: 28% (59 aa) FAPKCL-ALISRLEYFETLKNCLGLMYTVYV--DNVEVEME-TLVGNILGHVQVPPPGGPQVR------FSIG-AGDRQ---ALQPPLSDSLPVSR--SS ..|||. .||.. .|.. ...| .|.... .| .. .. .. ... |..||||...| |... .|... .. |....||.. .. WTPKCIHCIISHHPWFNWFRKWLNELYRYWQSDHNQHLFHHEFMIYLCHYPVPLPPPGKSIVFMSIVSYFQFHPPGNYYQPIEFCRPDDNRLPHIDENWD VALLVQQLGIHNIITLFCAAVTDQKIMFHCRSYTRLTEACGALISLLFPLKYSYVYIPVLPAALIEVLSTPTPFIMGIHSALKEEATELLD----VIVAD ...|...||. ||..|||.... ..| ||...|..|. .| |...||.|.... .|||.||| ....|..|.|.|||.|| . ||.....| |.| | LHELFECLGVENIMQLFCCILLERRIIFHSSNYQMLSMCCHAFVALLYPFQWQHIYIPILPASMLDYLCAPMPYIMGCHSSYFEEVKPEPDEEDDVVVVD LDGG .| . IDTN |
|||||||||
| GRAM | Spur_hmm73208.AA | GRAM | 793-883 | 14 | 4.3e-11 | 42.74 | Pfam | 1-78 (78) | Show / Hide |
Range on Protein: 793-883 Range on HMM: 1-78/78 Sequence Identity: 14% (14 aa) LDYTPKILKPTFLPGEEKVMEG----LRGYLVLDGREEGQGGVMGGPTLLPAEGAVFLTTYRIIFKGTPIDMQACEQVVTRSFPVSALVKEKKIN .... |. |. .||..||. . . .| .. |..|. |....|.....|.. . . .. .... .| ..... .|. EKFR-KHFKD-PLPPNEKLIMDCNVTYSCCLWRPF------------TKIPVQGRMYITNHHVCFYSDKFGWET---YYKMVIPWNDITRVEKMQ |
|||||||||
| Myotub-related | Spur_hmm73208.AA | Myotub-related | 1104-1331 | 10 | 2.1e-19 | 75.49 | Pfam | 1-89 (121) | Show / Hide |
Range on Protein: 1104-1331
Range on HMM: 1-89/121
Sequence Identity: 10% (25 aa)
FEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSS----GF-HGKG-----VMGMIKSAQTQGSSTSESSGSSKSLEQEKYLS
.|....|||..|||. .||| ....||. ..||.|...||||... ...|.| |. .... .. |..|
YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCKEDEKLVQAIMKANA-D--------------------
AIVLNTPYGSAHKSDSLVSLNSILPPTNSGETPDGTPTISPRKGTHGTGTLLQRGFLRSSGGQKAYTGKPGNTLKGGGRLMMGASGHTQLGGGVSPAISK
----------------------------------------------------------------------------------------------------
KHLTLGSRTSATRNGSVTEQDLAMPRKQEARKAALYVF
.... .|..
----------------------------MIQSRKMYIV
|
|||||||||
| GRAM | Spur_hmm73208.AA | GRAM | 793-883 | 15 | 4.7e-10 | 40.65 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 793-883 Range on HMM: 1-80/80 Sequence Identity: 15% (15 aa) LDYTPKILKPTFLPGEEKVMEG------LRGYLVLDGREEGQGGVMGGPTLLPAEGAVFLTTYRIIFKGTPIDMQACEQVVTRSFPVSALVKEKKIN .. .. | || .||. . || .. .|. | .......|.|.. . . ..|.|......| . ... .|. EKFR-QHFK---LPPNEKLINDCKKEVTYSCYLWRTY-------------DIPVQGHMYISNNHICFCSNMFGWMTCPQYYKVVIPWADITRIEKMT |
|||||||||
| Phosphatase | Spur_hmm73208.AA | Family.Myotubularin.PD | 1382-1516 | 43 | 2.2e-48 | 151.8 | In-house | 4-139 (141) | Show / Hide |
Range on Protein: 1382-1516 Range on HMM: 4-139/141 Sequence Identity: 43% (59 aa) EMGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVDKEWLAFGHRFTHRTNQTIT-HQTSG |. ... . ...|| .|. ... | |. .. ...|| . |||| |.|...|||||.||||||. ||.||..||||.|||.|..|. .. . .... ekkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdkseseee FAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYH .||||||.|||.|.. ||| .||||. || .|. | rsPvflqfidcvyqltkqfptafefnesflikildh |
|||||||||
| Phosphatase | Spur_hmm73208.AA | Subfamily.MTMR3.PD | 1389-1516 | 47 | 4.5e-42 | 131.5 | In-house | 5-133 (135) | Show / Hide |
Range on Protein: 1389-1516 Range on HMM: 5-133/135 Sequence Identity: 47% (61 aa) VGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVDKEWLAFGHRFTHRTNQTIT-HQTSGFAPVFLQ . ...|| .. ... | |. .| .| | . |||| |.|. |||.||.||||||| ||||||..||| |||.|. |. .. .... .||||| lektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercpvflq FLDCVHQVHSQFPLSFEFNQYFLKTIAYH .||||||.. ||| |||||. || .. | wldcvhqlkkqfptsfefneaflvklvqh |
|||||||||
| Phosphatase | Spur_hmm73208.AA | Subfamily.MTMR1.PD | 1382-1516 | 47 | 8.2e-42 | 130.8 | In-house | 12-147 (149) | Show / Hide |
Range on Protein: 1382-1516 Range on HMM: 12-147/149 Sequence Identity: 47% (62 aa) EMGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVDKEWLAFGHRFTHRTNQTI-THQTSG | ... . |..|| .|. |.. | ..| .. . .|| . |||| |.|...|| ||.|.||||. ||.||..||||.|||.|..|.| . .|||| eskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighgdknhadad FAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYH ||.||| || ||| .||||..|| || | rspvflqfidcvwqvtrqfptafefneeflitildh |
|||||||||
| Phosphatase | Spur_hmm73208.AA | Subfamily.C2-MTMR1.PD | 1389-1516 | 42 | 5.2e-39 | 121.8 | In-house | 10-135 (137) | Show / Hide |
Range on Protein: 1389-1516 Range on HMM: 10-135/137 Sequence Identity: 42% (54 aa) VGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVDKEWLAFGHRFTHRTNQTitHQTSGFAPVFLQF . ...|| |. ... | | .. . | . |||| |.|. .|||||.||||||. |..||..||||||||.| .| ... .| .|.|||||| lestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlgga--dsvserspiflqf LDCVHQVHSQFPLSFEFNQYFLKTIAYH |..||. ||| .||.. .| .| . ldclyqvtkqfpsafeytarlllklady |
|||||||||
| C1 | Spur_hmm73208.AA | C1 | 1739-1791 | 33 | 4e-16 | 60.82 | SMART | 1-61 (61) | Show / Hide |
Range on Protein: 1739-1791 Range on HMM: 1-61/61 Sequence Identity: 33% (21 aa) HHFEPCSYMTPTSCDFCNQMLFGVVKQ--GCTGMKCSDCGYNVHEKCVPQVPK-------QC ||.. .. .|| |. |..|..|. || . .|..||.|.|..|.||...||. | HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC |
|||||||||
| C1 | Spur_hmm73208.AA | C1_1 | 1739-1794 | 31 | 5.1e-14 | 55.11 | Pfam | 1-55 (55) | Show / Hide |
Range on Protein: 1739-1794 Range on HMM: 1-55/55 Sequence Identity: 31% (18 aa) HHFEPC-SYMTPTSCDFCNQMLFGVVK-QGCTGMKCSDCGYNVHEKCVPQVPKQCSRR ||... .. ||.|. |.... |..|.||..|.||.|..|...||. | HHWVHHWNFKQPTFCCHCGEFC---WGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN |
|||||||||
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Spur_hmm73208.AA | Protein | None | 1941 | None | Fasta, JSON |
| Spur_hmm73208.NA | RNA | None | 5823 | None | Fasta, JSON |