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Gene Spur_hmm242189,hmm82360

Spur_hmm242189,hmm82360
Species: S.purpuratus
Alias: Spur_hmm242189,hmm82360
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Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Myotubularin
Subfamily: MTMR6
Protein domain

Protein domains of Spur_hmm242189,hmm82360.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Myotub-related Spur_hmm242189,hmm82360.AA Myotub-related 165-208 52 2.7e-17 67.62 Pfam 1-44 (121) Show / Hide 
Range on Protein: 165-208
Range on HMM: 1-44/121
Sequence Identity: 52% (23 aa)

YEICDTYSRTLYVPTHASPPVLVGSSRFRSRGRLPVLSYLHQEN
||||.|| ..|.||. .|  .|.....|||.||.|||...||||
YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQEN
Phosphatase Spur_hmm242189,hmm82360.AA Family.Myotubularin.PD 244-377 57 5.6e-63 200.1 In-house 5-140 (141) Show / Hide 
Range on Protein: 244-377
Range on HMM: 5-140/141
Sequence Identity: 57% (78 aa)

EAFLSGLESSQWMKHIKAVLDTSLFIAKAIADEGLSVLVHCSDGWDRTAQTCSLASIILDPYYRTIQGFQVLIEKEWLAFGHKFLHRCGLLA--YDPREV
. .|| |||..|..|||..|...  |.... .|. ||||||||||||||| .|||...||||||||.||.||||||||.||||| .|.|     .. .| 
kkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdkseseeer

SPVFTQFIECTWQLCQQFPCAFQFNERFLLELHDHV
||||.|||.| .||..|||.||.|||.||....||.
sPvflqfidcvyqltkqfptafefnesflikildhl
Phosphatase Spur_hmm242189,hmm82360.AA Subfamily.C2-MTMR1.PD 246-377 56 9.8e-55 173.7 In-house 6-136 (137) Show / Hide 
Range on Protein: 246-377
Range on HMM: 6-136/137
Sequence Identity: 56% (73 aa)

FLSGLESSQWMKHIKAVLDTSLFIAKAIADEGLSVLVHCSDGWDRTAQTCSLASIILDPYYRTIQGFQVLIEKEWLAFGHKFLHRCGLlAYDPREVSPVF
.|| |||.||. .|||||...  ||. . . ..| |||||||||||.|  .|| ..||||||||.|..|||||||||||||| .| ||  . | ||.| |
wlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlgg-adsvserspif

TQFIECTWQLCQQFPCAFQFNERFLLELHDHV
|..| .|. .|||.||... |.|| | |..  
lqfldclyqvtkqfpsafeytarlllkladys
Phosphatase Spur_hmm242189,hmm82360.AA Subfamily.MTMR1.PD 244-378 56 1.9e-54 172.8 In-house 13-149 (149) Show / Hide 
Range on Protein: 244-378
Range on HMM: 13-149/149
Sequence Identity: 56% (75 aa)

EAFLSGLESSQWMKHIKAVLDTSLFIAKAIADEGLSVLVHCSDGWDRTAQTCSLASIILDPYYRTIQGFQVLIEKEWLAFGHKFLHRCGL--LAYDPREV
. .|| ||...|..||| .|. .. ||...  |  ||.||||||||||||  ||| ..||.|||||.||.||||||||.||||| .| |.   . |||| 
skwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighgdknhadadr

SPVFTQFIECTWQLCQQFPCAFQFNERFLLELHDHVF
|||.| ||. .|||.||.|||.||. . ||..     
spvflqfidcvwqvtrqfptafefneeflitildhly
Phosphatase Spur_hmm242189,hmm82360.AA Subfamily.MTMR3.PD 246-377 54 7.6e-53 167.4 In-house 1-134 (135) Show / Hide 
Range on Protein: 246-377
Range on HMM: 1-134/135
Sequence Identity: 54% (69 aa)

FLSGLESSQWMKHIKAVLDTSLFIAKAIADEGLSVLVHCSDGWDRTAQTCSLASIILDPYYRTIQGFQVLIEKEWLAFGHKFLHRCGLLAY--DPREVSP
||| ||...|..|. ..|.... ...|.  ||  ||||||||||||.|  .|| ..|||||||..||.||.|.||| |||||  ||||  | .||| |..
flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp

VFTQFIECTWQLCQQFPCAFQFNERFLLELHDHV
.| .|| .|||..|.||| ||. | .|       
vflqwldcvhqlkkqfptsfefneaflvklvqht
Phosphatase Spur_hmm242189,hmm82360.AA Subfamily.DSP3.PD 265-306 37 4.1e-06 15.8 In-house 77-117 (148) Show / Hide 
Range on Protein: 265-306
Range on HMM: 77-117/148
Sequence Identity: 37% (14 aa)

TSLFIAKAIADEGLSVLVHCSDGWDRTAqTCSLASIILDPYY
. ||..|.....  |||||  |  |.| |. || ...     
aadfidealsqkngkvlvhcvvGisRsa-tlvlayLmirrkl
FYVE Spur_hmm242189,hmm82360.AA FYVE 549-613 27 6e-06 16.09 SMART 1-81 (81) Show / Hide 
Range on Protein: 549-613
Range on HMM: 1-81/81
Sequence Identity: 27% (22 aa)

SVATEWQSFRHIRQC--SCSSPFDY-FSRKYHCWKCGEVFCIRCIDKQTQLPGHESQR---------PVPVCRPCY----R
 ....||  .    |   |. .|   ..|. || .|| .|| .| .|.  || ..  .         || ||..||    .
ETKPHWQPDEEVDHCCMNCRKEFNFVTNRRHHCRHCGRIFCSKCCNKWIPLPYMGNYKKNGNNQNFTPVRVCDDCYEMMHH
FYVE Spur_hmm242189,hmm82360.AA FYVE 552-614 31 1.2e-12 45.88 Pfam 1-68 (71) Show / Hide 
Range on Protein: 552-614
Range on HMM: 1-68/71
Sequence Identity: 31% (22 aa)

TEWQSFRHIRQCS-CSSPFDYF-SRKYHCWKCGEVFC--IRCIDKQTQL--PGHESQRPVPVCRPCYRE
..||   .. .|. |..||  |  |. || .|| .||    | ...  .  | . . .|| ||. ||..
PHWQPDSEVTHCMICQKPFTFFGRRRHHCRHCGRIFCDDSKCSSHKCIPHPPYYGWNKPVRVCD-CYDD
Sequence
Name Sequence Type Origin Length Description Download
Spur_hmm242189,hmm82360.AA Protein None 614 None Fasta, JSON
Spur_hmm242189,hmm82360.NA RNA None 1842 None Fasta, JSON
Spur_hmm242189,hmm82360.AA.PD_246-378 Protein Phosphatase Domain None 133 None Fasta, JSON