spur_hmm179643,hmm38405,hmm127473
Species: S.purpuratus
Alias: spur_hmm179643,hmm38405,hmm127473
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-II
Family: CDC25
Subfamily: CDC25
Protein domain

Protein domains of spur_hmm179643,hmm38405,hmm127473.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Rhodanese spur_hmm179643,hmm38405,hmm127473.AA RHOD 477-593 25 1.2e-22 82.52 SMART 1-94 (94) Show / Hide
Range on Protein: 477-593
Range on HMM: 1-94/94
Sequence Identity: 25% (30 aa)

CRLLRSEYDQEIAECHVIDCRYPYEFNGGHIKGAINIYEEAELKKMFLENPLPPLPNNGRRVYVFHCEFSSQRG-PKMLRLLRAQDRSANLENYPALYYP
. ... . .|. ..| .||||.|||..||||.|||||  .. |..         |  . ..  ...| .|. |. |.. ..||.....            
V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR---------LGIDKDKPVIVYC-RSGNRSAPRAAWWLREAGYK------------

ELYLLNEGYKAFFEYSTE
. |.|. |.|....   .
NVYILDGGWKEWKRACPP

Phosphatase spur_hmm179643,hmm38405,hmm127473.AA Family.CDC25.PD 478-591 55 1.6e-50 157.8 In-house 2-115 (117) Show / Hide
Range on Protein: 478-591
Range on HMM: 2-115/117
Sequence Identity: 55% (62 aa)

RLLRSEYDQEIAECHVIDCRYPYEFNGGHIKGAINIYEEAELKKMFLENPLPPLPNNGRRVYVFHCEFSSQRGPKMLRLLRAQDRSANLENYPALYYPEL
.||..|....|.....||||||||..|||||||.|.|.. ||...||..|  .  .. |....|||||||.||||..|||| .||..| |.||.|.||||
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

YLLNEGYKAFFEYS
|||..|||.|||  
ylLegGykeffeev

Phosphatase spur_hmm179643,hmm38405,hmm127473.AA Group.Cx5R-II.PD 478-591 55 1.6e-50 157.8 In-house 2-115 (117) Show / Hide
Range on Protein: 478-591
Range on HMM: 2-115/117
Sequence Identity: 55% (62 aa)

RLLRSEYDQEIAECHVIDCRYPYEFNGGHIKGAINIYEEAELKKMFLENPLPPLPNNGRRVYVFHCEFSSQRGPKMLRLLRAQDRSANLENYPALYYPEL
.||..|....|.....||||||||..|||||||.|.|.. ||...||..|  .  .. |....|||||||.||||..|||| .||..| |.||.|.||||
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

YLLNEGYKAFFEYS
|||..|||.|||  
ylLegGykeffeev

Phosphatase spur_hmm179643,hmm38405,hmm127473.AA Subfamily.CDC25.PD 478-591 55 1.6e-50 157.8 In-house 2-115 (117) Show / Hide
Range on Protein: 478-591
Range on HMM: 2-115/117
Sequence Identity: 55% (62 aa)

RLLRSEYDQEIAECHVIDCRYPYEFNGGHIKGAINIYEEAELKKMFLENPLPPLPNNGRRVYVFHCEFSSQRGPKMLRLLRAQDRSANLENYPALYYPEL
.||..|....|.....||||||||..|||||||.|.|.. ||...||..|  .  .. |....|||||||.||||..|||| .||..| |.||.|.||||
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

YLLNEGYKAFFEYS
|||..|||.|||  
ylLegGykeffeev

Phosphatase spur_hmm179643,hmm38405,hmm127473.AA Rhodanese 480-590 21 5.7e-17 55.48 Pfam 1-102 (102) Show / Hide
Range on Protein: 480-590
Range on HMM: 1-102/102
Sequence Identity: 21% (25 aa)

LRSEYDQEI--AECHVIDCRYPYEFNGGHIKGA-INIYEEAELKKM-FLENPLPPLPNNGRRVYVFHCEFSSQRGPKMLRLLRAQ-DRSANLENYPALYY
.  .... .   ....||.| |.|...|||.|| .||     |... .||.    |... .  .|..|  ...|.  . ..|...  ...  .       
TPEWLKEMMNDPDYVIIDVRPPEEYEKGHIPGAHVNIPW---LEEEHDLEELGIKLDKDKPI-IVVYC--HGNRSG-AWACLVWWMLKAMGYP-------

PELYLLNEGYKAFFEY
|. |.|. |..|. . 
PNVYVLDGGWEAWKAE

Sequence
Name Sequence Type Origin Length Description Download
spur_hmm179643,hmm38405,hmm127473.AA Protein None 636 None Fasta, JSON
spur_hmm179643,hmm38405,hmm127473.NA RNA None 1908 None Fasta, JSON
spur_hmm179643,hmm38405,hmm127473.AA.PD_477-593 Protein Phosphatase Domain None 117 None Fasta, JSON