spur_hmm43544,hmm216903
Species: S.purpuratus
Alias: spur_hmm43544,hmm216903
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: EYA
Subfamily: EYA
Protein domain

Protein domains of spur_hmm43544,hmm216903.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase spur_hmm43544,hmm216903.AA Family.EYA.PD 331-577 87 2.1e-159 515.9 In-house 1-247 (247) Show / Hide
Range on Protein: 331-577
Range on HMM: 1-247/247
Sequence Identity: 87% (215 aa)

ERVFVWDLDETIIIFHSLLTGSYATRFGKDAPAAVSLGLRMEEMIFNLADMHLFFNDLEECDQVHIDDVASDDNGQDLSNYNFQTDGFHAAATSANLCLA
||||||||||||||||||||||||...||||...|.||||||||||||||.||||||||||||||||||.|||||||||.|||.||||||||||||||||
ervfvwdldetiiifhslltgsyaekygkdasssvalglrmeemifnladthlffndleecdqvhiddvssddngqdlstynfatdgfhaaatsanlcla

TGVRGGVDWMRKLAYRYRRIKEIYSSYKNNVGGLLGPQKREQWLQLRAEIEAMTDSWLTIALKSLSIIHSRSNCINVLVTTTQLVPAVAKVLLYGLGGVF
||||||||||||||.|||..||||.||||||||||||.|||.||||||||||.||||||.|||.||.|.|||||.||||||||||||.||||||||||||
tgvrggvdwmrklafryrkvkeiynsyknnvggllgpakreawlqlraeiealtdswltlalkalslissrsncvnvlvtttqlvpalakvllyglggvf

NIENVYSATRVGKESCFERIVARFGRKVTYVAIGDAKDEETAAKQLD
.|||.||||..||||||||||||||||||||.|||.||||||||.|.
pieniysatkigkescferivarfgrkvtyvvigdgkdeetaakkln

Phosphatase spur_hmm43544,hmm216903.AA Subfamily.EYA.PD 331-577 87 2.1e-159 515.9 In-house 1-247 (247) Show / Hide
Range on Protein: 331-577
Range on HMM: 1-247/247
Sequence Identity: 87% (215 aa)

ERVFVWDLDETIIIFHSLLTGSYATRFGKDAPAAVSLGLRMEEMIFNLADMHLFFNDLEECDQVHIDDVASDDNGQDLSNYNFQTDGFHAAATSANLCLA
||||||||||||||||||||||||...||||...|.||||||||||||||.||||||||||||||||||.|||||||||.|||.||||||||||||||||
ervfvwdldetiiifhslltgsyaekygkdasssvalglrmeemifnladthlffndleecdqvhiddvssddngqdlstynfatdgfhaaatsanlcla

TGVRGGVDWMRKLAYRYRRIKEIYSSYKNNVGGLLGPQKREQWLQLRAEIEAMTDSWLTIALKSLSIIHSRSNCINVLVTTTQLVPAVAKVLLYGLGGVF
||||||||||||||.|||..||||.||||||||||||.|||.||||||||||.||||||.|||.||.|.|||||.||||||||||||.||||||||||||
tgvrggvdwmrklafryrkvkeiynsyknnvggllgpakreawlqlraeiealtdswltlalkalslissrsncvnvlvtttqlvpalakvllyglggvf

NIENVYSATRVGKESCFERIVARFGRKVTYVAIGDAKDEETAAKQLD
.|||.||||..||||||||||||||||||||.|||.||||||||.|.
pieniysatkigkescferivarfgrkvtyvvigdgkdeetaakkln

Phosphatase spur_hmm43544,hmm216903.AA Group.HAD.PD 332-559 19 6.9e-38 118.4 In-house 2-190 (190) Show / Hide
Range on Protein: 332-559
Range on HMM: 2-190/190
Sequence Identity: 19% (44 aa)

RVFVWDLDETIIifhslLTGSYATRFGKDAPAAVSLGLRMeemifNLADMHLFFNDLEECDQVHIDDVAsddngqdlsnynFQTDGFHAAA---------
...|.|||....     |.||.... |.. .. | ..|..     | ....|.... ..........|.            . .|.|....|... . |.
dtlvlDldgvlw-----lhgspepleglrskgkvlifltn-----natksrlyllkrlallgflveeve------------phldeflervgelyelvvf

TSANLCLATGVRGGVDWMrKLAYRYRRIKEIYSSYKNnVGGLLGPQKReqwlqlraeieamTDSWLTIALKSLSIIHSRSNCINVLVtttqlvpAVAKVL
 |.|.||.. ..|..||.... .. .|. .|.||....|             ....|. .|....||. .... ..... ...|..|      |.....|
tagtreyadpvvgavdvg-deafsyrklrdacvylkg-pgalllatnr-------------dlgalvrdlekvviidnkpsvfafec-------npenal

LYGLGgvfnIENVYSATRVGKESCFERIVARFGRKVT
...|.....|.|. |||..|.                
migdf----iddildaellglipdlenidvrfgkdvg

Phosphatase spur_hmm43544,hmm216903.AA Hydrolase 331-577 9 1.6e-08 30.66 Pfam 1-167 (167) Show / Hide
Range on Protein: 331-577
Range on HMM: 1-167/167
Sequence Identity: 9% (25 aa)

ERVFVWDLDETIIIF----HSLLTGSYATRFGKDAPAAVSLGLRMEEMIF-NLADMHLFFNDLEECDQVHIDDVASDDNGQDLSNYNFQTDGFHAAATSA
 ...|.|.| |.. .    |   . . | ..|. .|...   .  ... . . .| .  . ..                                     
IKAVVFDKDGTLTDGSEHPHAQAWVEAAREYGY-WPFEEVEYIWGRGI-GDRIIDWWRATDEHI------------------------------------

NLCLATGVRGGVDWMRKLAYRYRRIKEIYSSYKNNVGGLLGPQKREQWLQLRAEIEAMTDSWLTIALKSLSIIHSRSNCINVLVTTTQLVPAVAKVLLYG
                                                   . ...|  | ..  | . |  .... ..  ...| .   .|.|.. ..|
------------------------------------------------D-EYLGVIAD-DQPYPGAREALQALKRM-GIKVAMITNDNR-NAQAVLEHLG

LGGVFNIENVYSATRV---GKESCFERIVARFGRKVT---YVAIGDAKDEETAAKQLD
..  |..  ... . .    .  ..|... |.| |.    ....||.     ...| .
IA-YFDHIIDSDDVGIVGKPHPEMYEKACQRLGVKPHECGCMMVGDGINDDPMLAQAG

Sequence
Name Sequence Type Origin Length Description Download
spur_hmm43544,hmm216903.AA Protein None 601 None Fasta, JSON
spur_hmm43544,hmm216903.NA RNA None 1803 None Fasta, JSON
spur_hmm43544,hmm216903.AA.PD_331-577 Protein Phosphatase Domain None 247 None Fasta, JSON