Gene spur_hmm283404,hmm144934
spur_hmm283404,hmm144934
Species: S.purpuratus
Alias: spur_hmm283404,hmm144934
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of spur_hmm283404,hmm144934.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | spur_hmm283404,hmm144934.AA | Subfamily.FCP1.PD | 54-200 | 52 | 3e-65 | 208.1 | In-house | 1-149 (150) | Show / Hide |
Range on Protein: 54-200 Range on HMM: 1-149/150 Sequence Identity: 52% (80 aa) RKLVLLVDLDQTLIHTTLD---EVPA-DMPGVHHFQLRKGPMfpWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRILSRD |||||.||||||||||| | ||.. .. ....|.|.. .. .|....|.|...||. .|..|.|||.||| | ||...|.|.|||.|.||.|||||| rklvLvvDlDqtlihttkdptievkeeklkdikkftlpeeke--vyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrd ECVDPHSKKANLRSIFPRGDKMVCIIDDRDDVWNFAPNLIQVPPYRYFEGT |.....||...|...||.||.||.|||||.||||||.|||.| ||..|.|. ellnassktkklkklfptgdsmvviiDDredvWnfaenlikvkpykfFkgv |
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| Phosphatase | spur_hmm283404,hmm144934.AA | CPDc | 54-201 | 30 | 1.9e-48 | 168.16 | SMART | 1-173 (173) | Show / Hide |
Range on Protein: 54-201 Range on HMM: 1-173/173 Sequence Identity: 30% (52 aa) RKLVLLVDLDQTLIHT------------TLDEVPADMPGVHHFQLRKGPMF---------PWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAE .|..| .|||.||.|. . . .. ... ..|| ..| ..... | .||. .|..| .|.|||| | ||..|.. KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD IIDPEGKFFSHRILSRDECVDPHSKKAN--LRSIFPR-GDKMVCIIDDRDDVWNFAP-NLIQVPPYRYFEGTG ..||..|.|..|.|.||.||. ..| . . |...| ..||.||||. |.|.. | |.|...|..|| . . MLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT |
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| Phosphatase | spur_hmm283404,hmm144934.AA | Family.FCP.PD | 54-195 | 33 | 1.8e-38 | 121.1 | In-house | 1-139 (164) | Show / Hide |
Range on Protein: 54-195 Range on HMM: 1-139/164 Sequence Identity: 33% (48 aa) RKLVLLVDLDQTLIHTTLDEVpADMPGVHHFQLRKgpMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRILsRDECVD .|..|..|||.||.|..|... .. |....... . ..... | . ..||. .|. |...|||.. | ||..||.|.|||.|.|..|.| ||||| kkklLVlDLdetLvhselkpk-nkpdfvvkveide--leetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrll-rdecvl PHSKK-ANLRSIfPRGDKMVCIIDDRDDVWNFAP-NLIQVPPYR .... .|... .|....|.||||. |.... | |.|.|.... vkgnyvkdLskl-grdlskviiiDdspdsyklnpdnaikvksfk |
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| Phosphatase | spur_hmm283404,hmm144934.AA | NIF | 56-202 | 24 | 2.6e-22 | 82.97 | Pfam | 1-164 (189) | Show / Hide |
Range on Protein: 56-202 Range on HMM: 1-164/189 Sequence Identity: 24% (43 aa) LVLLVDLDQTLIHTT--LDEVPADMPGVHHFQLRK---GPMFPWYHTRI-RDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPE-GKFF-SHRIL- ..| ||| ||.|.. .... .| |... | .|| ... | ..||. .|..| ..|.|.. . || | ..|||. .|.| .|..| KTLVLDLDETLVHCNPWWEPPN-----WHDFIVPIPFNGQNHQWY-VYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLI --SRDECV---DP--H-S-KKANLRSIFPRGD---KMVCIIDDRDDVWNF-APNLIQVPPYRYFE-----G-TGD .|..|. . . | .|. .. . . | |.|.. ..| . |.|..||| ... . | CWYREHCWLYRNGGNYYVKK--DLSILW-YNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPY-WYGYHDDDDSPDD |
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| Phosphatase | spur_hmm283404,hmm144934.AA | Group.HAD.PD | 56-200 | 20 | 5.3e-22 | 67.8 | In-house | 2-163 (190) | Show / Hide |
Range on Protein: 56-200 Range on HMM: 2-163/190 Sequence Identity: 20% (33 aa) LVLLVDLDQTLI--HTTLDEVPADMPGVHHFQLRK--GPMFPWYHTRIR----------DNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFF .|..|||..|. . ....| ...|.. .. ... | . .. .||. ... | |..||.| | ||..|. ..|....||. dtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdeaf SHRILSRDECVDPHsKKAN------LRSIFPRGDKMVCIIDDRDDVWNF---APNLIQVPPYryfegT |.| .. .. . ..|. .. . |. ..|.|||....|..| .| . . .. syrklrdacvylkg-pgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdf-----i |
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| Phosphatase | spur_hmm283404,hmm144934.AA | Subfamily.HSPC129.PD | 56-178 | 27 | 1.2e-16 | 49.9 | In-house | 3-121 (164) | Show / Hide |
Range on Protein: 56-178
Range on HMM: 3-121/164
Sequence Identity: 27% (33 aa)
LVLLVDLDQTLIHTTLDEVPAdmpGVHHFQLRKGPMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRiLSRDECVDPH
|..|||.||.|..| ... ..|.. . . |.| ...||. .|. ... .|| ..||. . ...||| |.. ||| |. || ...
fslvldldetlvhcslakled---atlsfkveyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhr-lfrehcvcvd
SKKANLRSIFPRGDKMVCIIDDR
||. | . |.|.
gnyikdlsilGrdlsktiivdns
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| Phosphatase | spur_hmm283404,hmm144934.AA | Subfamily.DULLARD.PD | 56-193 | 24 | 2.2e-15 | 45.7 | In-house | 3-145 (172) | Show / Hide |
Range on Protein: 56-193 Range on HMM: 3-145/172 Sequence Identity: 24% (35 aa) LVLLVDLDQTLIHTTLDEVPAD--MPGV-H--HFQLRKGPMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRILsRDE .|..|||.||||.. |.| .|. . .... . .. | ||| .|..|.| ||| ... ||..|.. .| . ....| |..|. ktlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryy-rqh CVDPHSKKA-NLRSIfPRGDKMVCIIDDRDDV-WNFAPNLIQVPP ..| .| . . |.|.|. ... | |.. Ctlesgkytkdlslv-sedlssviilDnspvayrknpdnaipiks |
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| Phosphatase | spur_hmm283404,hmm144934.AA | Subfamily.SCP.PD | 55-202 | 26 | 2.7e-13 | 38.8 | In-house | 2-143 (163) | Show / Hide |
Range on Protein: 55-202 Range on HMM: 2-143/163 Sequence Identity: 26% (39 aa) KLVLLVDLDQTLIHTTLDEVPADMPgVHHFQLrKGPMFPWYHTRiRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKfFSHRiLSRDECVDP | |..|||.||.|... |. | .. .| .. | .. | ..||. ... ... .|| . ||. ||...|.... ...| ||..|| . kkclvldldetlvhssfkpvenadf-vvpvei-dgtvhqvyvlk-rpfvdeflkkvgelfevvlftaslakyadpvadlldkknv-ikar-lfrescvfh HSKKANLRSIFPRGDKMVCIIDDRDDVWNFAPNLiQVPPYRYFEGTGD .. | . | | | |.|. . | |. || .|. . | kgnyvkdlsrlGrdlkkvvivdnspasyifhpdn-avpveswfddeed |
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| Phosphatase | spur_hmm283404,hmm144934.AA | Subfamily.TIM50.PD | 95-193 | 19 | 1.5e-06 | 17.3 | In-house | 24-121 (150) | Show / Hide |
Range on Protein: 95-193 Range on HMM: 24-121/150 Sequence Identity: 19% (19 aa) YHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGkFFSHRiLSRDECVDPHSKKANLRSIFPRGDKMVCIIDDRDDVWNFAP-NLIQVPP . .. | ..||. ... ... .|| |.|. . . .||.. . ..| | || . . .. | . | . | ..| . ..| | ... . wrfkkrPgvdafleelaelfeivvftseqgltaaplidkldPkq-limyr-lfrdatkyvdGehvkdlsklnrdlskvivvdldkesvklqpenalalkk |
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| BRCT | spur_hmm283404,hmm144934.AA | BRCT | 335-425 | 17 | 2e-06 | 26.87 | Pfam | 1-84 (84) | Show / Hide |
Range on Protein: 335-425 Range on HMM: 1-84/84 Sequence Identity: 17% (17 aa) MRMSVLKGCNIVFSSVFPTNMPPEQSRV--WKVALALGAKVSPQIVTKSKEEQAKGRASTHLV--AAKV--GTSKV-HAARRSKSIFIVEPDWLWCCW ....||| ... . .... . . . ..|.|| .. . ||.. . . ..| ... .. |.|| |||.| |. H-EKPFKGCTFCI---TGGFDNMNRDEIHWQEMIEKHGGKV----------TDSVSKQTTHVIPWVGEPHCTRTKKFYWKAKEWNIPIVHPDWIWDCI |
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| BRCT | spur_hmm283404,hmm144934.AA | BRCT | 337-428 | 20 | 1.5e-07 | 32.33 | SMART | 1-93 (93) | Show / Hide |
Range on Protein: 337-428 Range on HMM: 1-93/93 Sequence Identity: 20% (21 aa) MSVLKGCNIVFS-SVFPTNMPPEQSRVWKVALALGAKVSPQIVTKSKEEQAKGRASTHLVAAKVGTSKV---------HAARRSKSIFIVEPDWLWCCWE | ..||| .... . ..|.. . . . ... ..|.||. .. | ||... . ...|. ... .. | || |||.| |.. MKPFKGCTFCITGDDIEGNFD-MRDELKEMIEMHGGKVT-SVSRK-----RC-PDTTHVIC-SPENPKYETWNRMMTKYMKAIAWGIWIVHPDWIWDCIK RW .| KW |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| spur_hmm283404,hmm144934.AA | Protein | None | 641 | None | Fasta, JSON |
| spur_hmm283404,hmm144934.NA | RNA | None | 1923 | None | Fasta, JSON |
| spur_hmm283404,hmm144934.AA.PD_54-202 | Protein Phosphatase Domain | None | 149 | None | Fasta, JSON |