spur_hmm146889,hmm241049
Species: S.purpuratus
Alias: spur_hmm146889,hmm241049
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: TIM50
Protein domain

Protein domains of spur_hmm146889,hmm241049.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase spur_hmm146889,hmm241049.AA Subfamily.TIM50.PD 151-301 71 8.8e-81 258.0 In-house 1-150 (150) Show / Hide
Range on Protein: 151-301
Range on HMM: 1-150/150
Sequence Identity: 71% (108 aa)

PPYTLVLEMKDILVHPEWTYANGWRFKKRPGVEYFLQQAGpPLFEIVIYTSEQGFTAFPILDSLDPKGCIMYRLFRDATKYVNGHHVKDLSSLNRDLSKV
||||||||.||.||||||||..||||||||||..||.... .|||||..|||||.||.|..|.||||..|||||||||||||.|.||||||.||||||||
ppytlvlelkdvlvhpewtyktGwrfkkrPgvdafleela-elfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskv

IIVDCNAKSYQLQPKNALGLKKWEGNDDDRTLFELAAFLRTVAASGVEDVR
|.||....|..|||.||| ||||.||.|||.|..|.|||.|.|.|.|||||
ivvdldkesvklqpenalalkkwkGnaddrelldllaflktiatsevedvr

Phosphatase spur_hmm146889,hmm241049.AA CPDc 151-280 32 7.7e-57 196.06 SMART 1-173 (173) Show / Hide
Range on Protein: 151-280
Range on HMM: 1-173/173
Sequence Identity: 32% (56 aa)

PPYTLVLEMKDILVHP-----------------EWTYA----------------------NGWRFKKRPGVEYFLQQAGPPLFEIVIYTSEQGFTAFPIL
...||||.... |||.                 |||..                       .|..||||.|..||....  ..|....|...  .|.|.|
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCS-KWYEMHVFTMGMRMYADPVL

DSLDPKG-CIMYR-LFRDATKYVNGH-HVKD-LSSLNR-DLSKVIIVDCNAKSYQLQPKNALGLKKWEGNDDDR
| ||||.  ..|| |.||...|..|. .||| || .|| |||.|||.|.. .|. ..|.||.  |.| .. .|.
DMLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT

Phosphatase spur_hmm146889,hmm241049.AA NIF 153-301 33 2.8e-55 194.75 Pfam 1-189 (189) Show / Hide
Range on Protein: 153-301
Range on HMM: 1-189/189
Sequence Identity: 33% (65 aa)

YTLVLEMKDILVHPE--WTYA---------------NGWRFKK-RPGVEYFLQQAGPPLFEIVIYTSEQGFTAFPILDSLDP--KGCI--MYRL---FRD
.|||| . . ||| .  |..                 .|...| ||....|||..   ..||||.|. .  .| |..| .||  |...   .||   .|.
KTLVLDLDETLVHCNPWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHM-SKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLICWYRE

ATK-YVNG-HH-V-KDLSSL--NR-DLSKVIIVDCNAKSYQLQPKNALGLKK-WEG-----N-DDD--RTLFELAAFL-RTVAASGV-EDVR
... |.|| .. | |||| |  || |||.||||| .. |. ||| |..  .  | |     . .||  . |..|  || . .| ... .|||
HCWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWYGYHDDDDSPDDFWNELLDLLPFLIEYLA-LQCLDDVR

Phosphatase spur_hmm146889,hmm241049.AA Family.FCP.PD 152-301 38 8e-47 148.0 In-house 2-164 (164) Show / Hide
Range on Protein: 152-301
Range on HMM: 2-164/164
Sequence Identity: 38% (64 aa)

PYTLVLEMKDILVHPEWT---------------YANGWRFKKRPGVEYFLQQAGpPLFEIVIYTSEQGFTAFPILDSLDP-KGCIMYRLFRDATKYVNGH
..|||.....||| |..               ... ...||||....||.... .|.||||.|...  .| |..| ||| |.....||.||....|.|..
kklLVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvs-elyeiviftastrkyadpvadiLDpekklfkkrllrdecvlvkgn

HVKDLSSLNRDLSKVIIVDCNAKSYQLQPKNALGLKKWEGNDDDRTLFELAAFLRTVAaSGvEDVR
|||||.|.||||||||.|.. .||.|.|.||. .|.......|..|..|..||...| .  |||| 
yvkdLsklgrdlskviiiDdspdsyklnpdnaikvksfkedpkDteLldLlpflesla-ke-edvr

Phosphatase spur_hmm146889,hmm241049.AA Group.HAD.PD 153-301 24 2.1e-33 104.8 In-house 2-190 (190) Show / Hide
Range on Protein: 153-301
Range on HMM: 2-190/190
Sequence Identity: 24% (46 aa)

YTLVLEMKDILV-HPEWTYANGWRFKKR-------------------------------PGVEYFLQQAGPPlFEIVIYTSEQGFTAFPILDSLDP-KGC
.|||| ... |. |.......|.|.|..                               |....||...|.  .|.|..|.... .| |... .|.....
dtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgel-yelvvftagtreyadpvvgavdvgdea

IMYRLFRDATKYVNGHHVK------DLSSLNRDLSKVIIVDCNAKSYQL--QPKNALGLKKWEGNDDDRTLFELAAFLRTVAASGVEDVR
.||..|||. |..|....      ||. |.|||.||.|.|...... .  .|.||| ....  . .| .|. |  .| ... . ..||. 
fsyrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdfiddildaellglipdlenidvrfgkdvg

Phosphatase spur_hmm146889,hmm241049.AA Subfamily.SCP.PD 177-294 41 6.3e-31 96.0 In-house 42-158 (163) Show / Hide
Range on Protein: 177-294
Range on HMM: 42-158/163
Sequence Identity: 41% (48 aa)

KKRPGVEYFLQQAGpPLFEIVIYTSEQGFTAFPILDSLDPKGCIMYRLFRDATKYVNGHHVKDLSSLNRDLSKVIIVDCNAKSYQLQPKNALGLKKWEGN
.||| |. ||.. |  |||.|..|. .   | |..| ||.|. | .||||..  ...| .||||| | |||.||.|||   .|| ..|.||... |  . 
lkrpfvdeflkkvg-elfevvlftaslakyadpvadlldkknvikarlfrescvfhkgnyvkdlsrlGrdlkkvvivdnspasyifhpdnavpveswfdd

DDDRTLFELAAFLRTVAA
.|. | .|  .| ...  
eedtelldllplleelsk

Phosphatase spur_hmm146889,hmm241049.AA Subfamily.HSPC129.PD 177-301 37 4.9e-26 80.2 In-house 42-164 (164) Show / Hide
Range on Protein: 177-301
Range on HMM: 42-164/164
Sequence Identity: 37% (47 aa)

KKRPGVEYFLQQAGpPLFEIVIYTSEQGFTAFPILDSLDPK-GCIMYRLFRDATKYVNGHHVKDLSSLNRDLSKVIIVDCNAKSYQLQPKNALGLKKWEG
. || ...||..    |||....|. .   |  .|| |||.   . .||||.    |.| ..|||| | ||||| |||| ..... .|.| . .. |  .
rlrpflreflervs-klfevilftaskkvyadklldlldpekklvrhrlfrehcvcvdgnyikdlsilGrdlsktiivdnspqafayqlenGipieswfa

NDDDRTLFELAAFLRTVAASgvEDVR
..|. |..| .||...|    |||| 
dendsellkllpfleklaek--edvr

Phosphatase spur_hmm146889,hmm241049.AA Subfamily.DULLARD.PD 175-293 33 3.5e-24 74.1 In-house 48-166 (172) Show / Hide
Range on Protein: 175-293
Range on HMM: 48-166/172
Sequence Identity: 33% (39 aa)

RFKKRPGVEYFLQQAGpPLFEIVIYTSEQGFTAFPILDSLDP-KGCIMYRLFRDATKYVNGHHVKDLSSLNRDLSKVIIVDCNAKSYQLQPKNALGLKKW
.  ||| |..||..     ...||.|.     | ...| ||  .| .  |..|.     .|...|||| .. |||.|||.|  ...|..|.||. .| | 
yvykrPhvdlfldvvs-kWydlviftasmeeyaaavvdkldsgrgilkrryyrqhCtlesgkytkdlslvsedlssviilDnspvayrknpdnaipiksw

EGNDDDRTLFELAAFLRTVA
 . .| .|..|  || ..  
isdpsdtallnllPfldalr

Sequence
Name Sequence Type Origin Length Description Download
spur_hmm146889,hmm241049.AA Protein None 358 None Fasta, JSON
spur_hmm146889,hmm241049.NA RNA None 822 None Fasta, JSON
spur_hmm146889,hmm241049.AA.PD_151-301 Protein Phosphatase Domain None 151 None Fasta, JSON