spur_hmm190855,hmm36310
Species: S.purpuratus
Alias: spur_hmm190855,hmm36310
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: UBLCP1
Protein domain

Protein domains of spur_hmm190855,hmm36310.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ubiquitin spur_hmm190855,hmm36310.AA UBQ 5-79 33 9.5e-15 56.24 SMART 1-72 (72) Show / Hide
Range on Protein: 5-79
Range on HMM: 1-72/72
Sequence Identity: 33% (26 aa)

MKLIVKWSGQ-EYEFTEVTGTD-TVKYLKEAIHEKTGVLPQRQKILGLKFKGKPPGDDVQLCALNIKPNTKIMMMGT
|.. |||... .. . ||. .| ||. ||..|..|.|. |..|. .   ..||   ||  | ..||.|...|..|..
MQIFVKWQNGWKTFTFEVKPSDWTVSELKQHIEDKEGIPPEQQRLI---YQGK-LEDD-TLADYNIQPGSTIHLMVR

Phosphatase spur_hmm190855,hmm36310.AA Subfamily.UBLCP1.PD 138-302 74 1.8e-98 315.6 In-house 1-165 (165) Show / Hide
Range on Protein: 138-302
Range on HMM: 1-165/165
Sequence Identity: 74% (123 aa)

GKKLLVLDVDYTFFDHRSVAENALELMRPNLHEFLTSAYEDYDIAIWSATNMKWIDVKMRELGVADNPNYKLAFMVDSRACITIHTQKYGIIETKPLGVI
||||||||||||..|||||||.||||.||.|.||||||||||||.|||||.||||.||..|||||||||||.||..||.|.|...|.|||.||.||||||
gkkllvldvdytlldhrsvaedalelkrpyleefltsayedydiviwsatsmkwievklkelGvadnpnykiafvldstamikvttpkygvievkplgvi

WGKYEQYNPKNTIMFDDLRRNFLMNPQNGLKIRPFREAYKNRYHDKELMRLAKYLRDIAPLDDFS
|.|..... |||||||||||||||||.||||||||.||..||..||||..|.|||..||.|.|||
wkklkkfsskntimfddlrrnflmnpknGlkirpfkeadlnrdkdkellkltkylkeiakledfs

Ubiquitin spur_hmm190855,hmm36310.AA ubiquitin 10-81 29 2.4e-07 30.18 Pfam 1-73 (73) Show / Hide
Range on Protein: 10-81
Range on HMM: 1-73/73
Sequence Identity: 29% (23 aa)

KWSGQE---YEFTEVTGTDTVKYLKEAIHEKTGVLPQRQKILGLKFKGKPP-GDDVQLCALNIKPNT-KIMMMGTRE
|. ..    ..| || ..|||. ||..|..|.|. |..|. .   .|||.   |.  |  .||...  .|.|.    
KTLDGKGSTFTF-EVDPDDTVEQLKQKIQQKQGIPPDQQRLI---YKGKQLREDHRTLSDYNIQDGSFTIHMVLRQR

Phosphatase spur_hmm190855,hmm36310.AA Family.FCP.PD 139-301 25 2.2e-36 114.0 In-house 2-163 (164) Show / Hide
Range on Protein: 139-301
Range on HMM: 2-163/164
Sequence Identity: 25% (45 aa)

KKLLVLDVDYTFFDH----------------RSVAENALELMRPNLHEFLTSAYEDYDIAIWSATNMKWIDVKMRELGVAdNPNYKLAFMVDSRACItih
|||||||.|.|....                ....|.   ..||.|.|||....|.|.| |..|...|..| ....|. . ....|  .. |. ...   
kklLVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpe-kklfkkrllrdecvlv---

tqkYGiIETKPLGVIwgkyeQYNPKNTIMFDDLRRNFLMNPQNGLKIRPFREAYknryHDKELMRLAKYLRDIAPLDDF
   .|  ..|.|...     . . ...|..|| .... .||.|..|...|.|.     .|.||..|...|...|  .|.
---kg-nyvkdLskl-----grdlskviiiDdspdsyklnpdnaikvksfkedp----kDteLldLlpfleslakeedv

Phosphatase spur_hmm190855,hmm36310.AA NIF 140-302 21 4.9e-25 92.79 Pfam 1-189 (189) Show / Hide
Range on Protein: 140-302
Range on HMM: 1-189/189
Sequence Identity: 21% (43 aa)

KLLVLDVDYTFFDHRSVAENALELM-----------------------RPNLHEFLTSAYEDYDIAIWSATNMKWIDVKMRELGVADNPN-YKLA--FMV
|.|||| |.|  ...    .. | .                       || ..||| .. ..|.| ||.| .... |  .. .     |.  |.     .
KTLVLDLDETLVHCN----PWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYID----PKSKKYFDGHHR

D---SR-ACITIHTQKYG--I-IETKPLGVIWGKYEQYNPKNTIMFDDLRRNFLMNPQNGLKIRP-FREAYKNR--YHD--KELMRLAKYL-RDIA-PL-
    .| .|.    ...|    .  | | ..|  |  .. ...|..|.  ... ..|.||..| | . .. ...   .|  .|| .|  .| . .|    
LICWYREHCWL---YRNGGNYYV-KKDLSILW--YNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWYGYHDDDDSPDDFWNELLDLLPFLIEYLALQCL

DDFS
||. 
DDVR

Phosphatase spur_hmm190855,hmm36310.AA Group.HAD.PD 139-300 19 1.7e-24 75.8 In-house 1-186 (190) Show / Hide
Range on Protein: 139-300
Range on HMM: 1-186/190
Sequence Identity: 19% (37 aa)

KKLLVLDVDYTFF---------DHRSVAENALELMR------------------------PNLHEFLTSAYEDYDIAIWSATNMKWIDVKMRELGVAdNP
|..||||.| . .          .|| . ....|..                        |.|.|||....|.|.. ...|..... |.... ..|... 
kdtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvg-de

NYKLAFMVDSRACITIHTQKYGIIETkPLGVIWGKYEqynpkNTIMFDDLRRNFLM--NPQNGLKIRPFreayKNRYHDKELMRLAKYLRDIAPLDD
..  .. |. ...  .. . ..  .  ||... ..|     .....|. ...| .  ||.|.| | .|    ... .|.||. | ..|  |...   
afsyrklrdacvylkgpgalllatnr-dlgalvrdle-----kvviidnkpsvfafecnpenalmigdf----iddildaellglipdlenidvrfg

Phosphatase spur_hmm190855,hmm36310.AA CPDc 138-279 16 1.5e-19 72.19 SMART 1-173 (173) Show / Hide
Range on Protein: 138-279
Range on HMM: 1-173/173
Sequence Identity: 16% (31 aa)

GKKLLVLDVDYTF-------------FDHRSVAENALE---------------------------LMRPNLHEFLTSAYEDYDIAIWSATNMKWIDVKMR
.||.|||| |.|              ...||..|.  .                           ..|| .||||. ... |.. .... .... |    
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYAD----

ELGVADNPNYKLAFMVDSRA-CITIH-------TQKYGIIETKP-LGVIWGKYEQYNPKNTIMFDDLRRNFLMNPQNGLKIRPFREAYKNR
          ... | |.    .  .       . . |   .|. | ...     ......|. || .. ....|.|...|.|..  ....
----------PVLDMLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNR----CDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT

Phosphatase spur_hmm190855,hmm36310.AA Subfamily.HSPC129.PD 164-300 22 7.4e-06 14.5 In-house 43-162 (164) Show / Hide
Range on Protein: 164-300
Range on HMM: 43-162/164
Sequence Identity: 22% (30 aa)

MRPNLHEFLTSAYEDYDIAIWSATNMKWIDVKmreLGVADNPNYKLAFMVDSRACITIHTQkYgiieTKPLGVIwGKyeqyNPKNTIMFDDLRRNFLMNP
.|| |.|||    . ... ...|..  . |     | . |  . ..   .    |. .... |     | | .. |.    . ..||.|.  . | .. .
lrpflreflervsklfevilftaskkvyadkl---ldlldpekklvrhrlfrehcvcvdgn-y----ikdlsil-Gr----dlsktiivdnspqafayql

QNGLKIrpfrEAYKNRYHDKELMRLAKYLRDIAPLDD
||. |    |.. .  .|.||..| ..|...| ..| 
enGipi----eswfadendsellkllpfleklaeked

Sequence
Name Sequence Type Origin Length Description Download
spur_hmm190855,hmm36310.AA Protein None 318 None Fasta, JSON
spur_hmm190855,hmm36310.NA RNA None 954 None Fasta, JSON
spur_hmm190855,hmm36310.AA.PD_138-302 Protein Phosphatase Domain None 165 None Fasta, JSON