• Phosphatome.Net

Gene XP_001193132

XP_001193132
Species: S.purpuratus
Alias: XP_001193132
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: NagD
Subfamily: PGP
Protein domain

Protein domains of XP_001193132.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase XP_001193132.AA Subfamily.PGP.PD 19-259 50 7.89999999999e-103 331.3 In-house 1-243 (243) Show / Hide 
Range on Protein: 19-259
Range on HMM: 1-243/243
Sequence Identity: 50% (123 aa)

IDTILLDCDGVLWHSNMAFPGAAETINKLRSMGKQPIFVTNNSTKSRLQYQEKFTKMGFIVSK-DEIFGTAYCAALYLKH-KLNF-TGKVYLMGMSGLEE
.||.|.|||||||....|.|||.|..|.||..||. .||||||||.| .| .||.|.|| |.| .||. .|...| |||. |... . ||||.|..||.|
fdtvlfDcdGVlWlgetaipgavevlnaLraagKkvlfvtNnstktreeylkkfkklgfkvlkkeeilssaavladylkqakakkekkkvyligeeglke

EMKLHSIDYIGTGPDNVEGQILDHRADHVVLDPDVNGVVVGFDQYFSFMKLLKAASYLKRPNSVFIGTNIDQQFPmRNSELIMPGTGSLVRPVEVASNRT
|.. ..|...|.|||..|... .. |..| |..||. ||||||..||..||.||..||..|.. |..|| |...| .|.|...|||||||. ||.||.|.
eleelgieslgvgpdkledeldgdlaekvklekdvgaVvvgfdehfsyvklakAlnylqnpdvlfvatneDetlp-lnpevvipgtGslvaavetasgre

ATTLGKPSKFMFECIQEKFDVNPQRTIMIGDRLNTDILLGKNCG
....|||||.......||....|.||.|.||||.||||.|||||
plvvGKPskllldallekakidpertlmvGDrldtDilfgkncG
Phosphatase XP_001193132.AA Family.NagD.PD 19-259 50 6.6e-95 305.5 In-house 1-239 (239) Show / Hide 
Range on Protein: 19-259
Range on HMM: 1-239/239
Sequence Identity: 50% (121 aa)

IDTILLDCDGVLWHSNMAFPGAAETINKLRSMGKQPIFVTNNSTKSRLQYQEKFTKMGFIVSKDEIFGTAYCAALYLKHKLNF--TGKVYLMGMSGLEEE
|||.|.|||||||... |.|||.|..|.||..||. .|||||||||| .. .|..|.|| ||..||| .|..|| |||.. .   . ||||.| .||.||
idtvlfDcdGVLwlgekaipgavealnrLrqkgkkvlfvTNnstksreellkklqklgfkvseeeifssaaaaadylkkrkkkpfkkkvyligeeglkee

MKLHSIDYIGTGPDNVEGQILDHRadHVVLDPDVNGVVVGFDQYFSFMKLLKAASYLKRPNSVFIGTNIDQQFpmRNSELIMPGTGSLVRPVEVASNRTA
.. ..|...|||||..|... ..   .| |..||. ||||.|..||..|| ||..||..|.  ||.|| |. .  ...| ..||.||.|..|.|..|.|.
leelgieslgtgpdkledeldgdl--evdlekdvgaVvvgadehfsyeklakAfryLqnpdvlfiatnedktl--kepevlipgaGsfvaaletatgrea

TTLGKPSKFMFECIQEKFDVNPQRTIMIGDRLNTDILLGKNCG
..|||||..||.. ||..|.|.||.|||||||||||....|| 
lvvGKPskllfealleklgvdpertvmiGDrlntDilfaqkcG
Phosphatase XP_001193132.AA Group.HAD.PD 19-261 34 3.4e-46 145.9 In-house 1-179 (190) Show / Hide 
Range on Protein: 19-261
Range on HMM: 1-179/190
Sequence Identity: 34% (76 aa)

IDTILLDCDGVLWhsnmaFPGAAETINKLRSMGKQPIFVTNNSTKSRLQYQEKFTKMGFIVSKDEifgtaycaalylKHKLNFTGKVylmgmsgleeemk
.||..||.|||||     ..|..|... |||.||..||.|||.|||||.........|| |...|            .|. .|. .||.. .|  . .  
kdtlvlDldgvlw-----lhgspepleglrskgkvlifltnnatksrlyllkrlallgflveeve------------phldeflerv-------------

lhsidyigtGPDnVEGQILDhRADHVVLDPDVNGVVVGfDQYFSFMKLLKAASYLKRPNSVFIGTNIdqqfpmrnselimpGTGSLVRPVEvasnRTATT
... ..||.|..|.|| |..||..|| .| .||| |.  .. ||               ..| ||| .|...   .||| |.|||       ||....||
---------gel-yelvvft-agtreyadpvvgavdvg-deafsyrklrdacvylkgpgalllatnr--------------dlgalvrdle----kvvii

LGKPSKFMFECiqekfdvNPQRTIMIGDRLnTDILLGKNCG----LK
||.. .|||   ..|    |.                          
dnkpsvfafec-------npenalmigdfi-ddildaellglipdle
Phosphatase XP_001193132.AA Subfamily.LHPP.PD 19-98 33 5.2e-17 50.2 In-house 1-80 (213) Show / Hide 
Range on Protein: 19-98
Range on HMM: 1-80/213
Sequence Identity: 33% (27 aa)

IDTILLDCDGVLWHSNMAFPGAAETINKLRSMGKQPIFVTNNSTKSRLQYQEKFTKMGFIVSKDEIFGTAYCAALYLKHK
|...|||  |||. ...| ||..| ...|.. | .  ||||.. .|. .  |. ...|| |...|.| ..  |. .||..
ikgvllDlsGvlyveeaaipgsveAlkrLkqsglkvrfvtnttkeskrelverLqrlgfkveeeevftslpaarqllkke
Phosphatase XP_001193132.AA Hydrolase 19-259 14 1.1e-15 55.18 Pfam 1-167 (167) Show / Hide 
Range on Protein: 19-259
Range on HMM: 1-167/167
Sequence Identity: 14% (37 aa)

IDTILLDCDGVLWHS-NMAFPGAAETINKLRSMGKQPIFVTNNSTKSRLQYQEKFTKMGFIVSKDEIFGTAYCAALYLKHKLNFTGKVYLMGMSGLEEEM
|.....|.||.|...   .   | . . ...                .... |... .|. .  |.|...........                      
IKAVVFDKDGTLTDGSEHPHAQAWVEAAREYGY-------------WPFEEVEYIWGRGI-G--DRIIDWWRATDEHI----------------------

KLHSIDYIGTGPDNVEGQILDHRADHVVLDPDVNGVVVGFDQYFSFMKLLKAASYLKRP-NSVFIGT---NIDQQFPMRNSELIMPGTGSLVRPVEVASN
                             | .. ||..  || .  ..  .|  .|||    |.. |     ..|  ..     ..| . ..  ..... 
-----------------------------D-EYLGVIAD-DQPYPGAR--EALQALKRMGIKVAMITNDNR-NAQAVLE-----HLGIA-YFDHIIDSDD

RTATTLGKPSKFMFECIQEKFDVNPQRT--IMIGDRLNTDILLGKNCG
..    |||.. |.| ..... |.|...  .|.||..|.|. | .  |
VG--IVGKPHPEMYEKACQRLGVKPHECGCMMVGDGINDDPMLAQ-AG
Phosphatase XP_001193132.AA Subfamily.LHPP.PD 150-259 29 1.6e-15 45.3 In-house 104-213 (213) Show / Hide 
Range on Protein: 150-259
Range on HMM: 104-213/213
Sequence Identity: 29% (33 aa)

VNGVVVGF-DQYFSFMKLLKAASYLKRPNS-VFIGTNIdQQFPMRNSELIMpGTGSLVRPVEVASNRTATTLGKPSKFMFECIQEKFDVNPQRTIMIGDR
| ||.|  .. |.. .| ||   |.  .. | |  .   ..  |...|.. ..|. |. .| | . .|. .|||||. ||   ....|.|....|||| .
pnavviglapesfnyetlnkafrlllekkkkvLiaigk-gkyykrkdglal-dvGafvkaLeyatdveaevvGkPsklfFesalqelgvdpeeavmiGDD

LNTDILLGKNCG
. |.   ...| 
vkdDvgGAqkvG
Sequence
Name Sequence Type Origin Length Description Download
XP_001193132.AA Protein None 306 None Fasta, JSON
XP_001193132.NA RNA None 918 None Fasta, JSON
XP_001193132.AA.PD_19-259 Protein Phosphatase Domain None 241 None Fasta, JSON