Gene Spur_hmm316291,hmm468784
Spur_hmm316291,hmm468784
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Spur_hmm316291,hmm468784.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP_Nematode_7.PD | 27-111 | 30 | 5.3e-14 | 41.8 | In-house | 197-282 (296) | Show / Hide |
Range on Protein: 27-111 Range on HMM: 197-282/296 Sequence Identity: 30% (26 aa) LDENQMSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVD || ... .... . .| || ..| | | . . .||. ..|||. .||. .. ||||.||...| . | | |. |. ldvqllaavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkve |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Family.PPP.PD | 35-116 | 43 | 1.8e-26 | 83.1 | In-house | 250-332 (349) | Show / Hide |
Range on Protein: 35-116 Range on HMM: 250-332/349 Sequence Identity: 43% (36 aa) IKSNNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCG-GSNEAACILVDRHK-LR ....|. |. ||.|..| ||.|.||. |||...||||||...|.......||.|.||...||| .||.|| . ||.. |. peeqkgwkpnk-RGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlkls |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Group.PPP.PD | 35-116 | 43 | 1.8e-26 | 83.1 | In-house | 250-332 (349) | Show / Hide |
Range on Protein: 35-116 Range on HMM: 250-332/349 Sequence Identity: 43% (36 aa) IKSNNGFVFNSrRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCG-GSNEAACILVDRHK-LR ....|. |. ||.|..| ||.|.||. |||...||||||...|.......||.|.||...||| .||.|| . ||.. |. peeqkgwkpnk-RGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlkls |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP5C.PD | 34-116 | 39 | 2.4e-22 | 69.2 | In-house | 254-336 (346) | Show / Hide |
Range on Protein: 34-116 Range on HMM: 254-336/346 Sequence Identity: 39% (33 aa) EIKSNNGFvFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRHKLR . ...|| .|.||.|. | | ..||. |||...||.|||.. |..|...|||.||||. || . | .| | . ..|. dpqeanGr-spskrGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlk |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP_Nematode_3.PD | 43-113 | 36 | 1.2e-17 | 53.9 | In-house | 225-296 (308) | Show / Hide |
Range on Protein: 43-113 Range on HMM: 225-296/308 Sequence Identity: 36% (26 aa) FNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV-DRH .| ||.|..| .|...||. .| |.|||.| . |.. . ||.|.||. ||| ...|..| |.. kesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvdkk |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP7C.PD | 32-110 | 36 | 7.3e-17 | 51.0 | In-house | 244-323 (338) | Show / Hide |
Range on Protein: 32-110 Range on HMM: 244-323/338 Sequence Identity: 36% (29 aa) MSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHY-CGGSNEAACILV |. |...| . |. ||.| | | ...|| ||. .||.|| .. |... . |.||.||.| | ||| | . . wsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvkl |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP3C.PD | 32-114 | 33 | 8.1e-17 | 51.2 | In-house | 184-273 (292) | Show / Hide |
Range on Protein: 32-114 Range on HMM: 184-273/292 Sequence Identity: 33% (30 aa) MSEIKSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQK------GKLLTVFSSSHYCGGSNEAACIL-VDRHK .| .... |. || || ...| |. .||| |.| .|||||.|.||.....| |.|.||.. |.. |. | .| .. .. ygeeetseeflpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennv |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP_Nematode_5.PD | 36-111 | 25 | 2.6e-16 | 49.3 | In-house | 184-260 (274) | Show / Hide |
Range on Protein: 36-111 Range on HMM: 184-260/274 Sequence Identity: 25% (20 aa) KSNNGFVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACI-LVD | ...| .| |. .| .. .|. ... ..|||||.. |.. . .|.||||...|.| . ... |. kdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvs |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP_Nematode_6.PD | 37-112 | 35 | 3.1e-15 | 45.9 | In-house | 184-259 (272) | Show / Hide |
Range on Protein: 37-112 Range on HMM: 184-259/272 Sequence Identity: 35% (27 aa) SNNGFVfNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAA-CILVDR . .|.. .. || . .| ||.. .|. .. |.|||.| | |.. . ||.|.||. |||| ..|| . ||. avkgwa-ensrGvsvvfGedavkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvde |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP1C.PD | 44-112 | 34 | 7.9e-15 | 44.9 | In-house | 189-258 (271) | Show / Hide |
Range on Protein: 44-112 Range on HMM: 189-258/271 Sequence Identity: 34% (24 aa) NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL-VDR .. || ..|. | .|.||. ..|. ..|||.| . |.. .| .|.|.||. ||| ..|.... || endrgvsftfgadvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvde |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP4C.PD | 44-113 | 34 | 1e-14 | 44.4 | In-house | 189-259 (271) | Show / Hide |
Range on Protein: 44-113 Range on HMM: 189-259/271 Sequence Identity: 34% (24 aa) NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACIL-VDRH | ||.|..| |. |.| . |... ..|||.. . |.... . |.|||.|. || . |.|| .| . vsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldee |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP6C.PD | 44-110 | 35 | 4.8e-14 | 42.1 | In-house | 189-255 (271) | Show / Hide |
Range on Protein: 44-110 Range on HMM: 189-255/271 Sequence Identity: 35% (23 aa) NSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILV | ||.|..| . |...|||. ..|||.. . |.. . . || ||.|. || . |.|| vsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasila |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP_Nematode_4.PD | 41-112 | 35 | 5.2e-14 | 42.1 | In-house | 186-257 (271) | Show / Hide |
Range on Protein: 41-112 Range on HMM: 186-257/271 Sequence Identity: 35% (24 aa) FVFNSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDR ..| ||....| . .| . .. .||||.| | |..| ||.|||| || ..||..| ewkasirgisytfgkgvvedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkld |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP_Nematode_2.PD | 36-116 | 26 | 2.3e-12 | 36.3 | In-house | 189-273 (281) | Show / Hide |
Range on Protein: 36-116 Range on HMM: 189-273/281 Sequence Identity: 26% (22 aa) KSNNGFVFnSRRGTGHMFSCDALERFLQVNNLSHVIRAHEV----QQAGFQVQQKGKLLTVFSSSHYCGGSNEAACILVDRHK-LR ...|. . | || | ..|.| . |.|. |.|||.. . | ... .|.|...||. | . |... . ..| |. tervgwsl-sargisfsfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsmkndssvlkleevktlq |
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Phosphatase | Spur_hmm316291,hmm468784.AA | Subfamily.PPP2C.PD | 39-113 | 32 | 1e-11 | 34.5 | In-house | 185-259 (271) | Show / Hide |
Range on Protein: 39-113 Range on HMM: 185-259/271 Sequence Identity: 32% (25 aa) NGFVFnSRRGTGHMFSCDALERFLQVNNLSHVIRAHEVQQAGFQVQQKGKLLTVFSSSHYCGGS-NEAACILVDRH .|. . | ||.|. | | |.| . |.|. | |||.. |.. .. ...|.||. || |.|| . .| . ggwgi-sprgagytfgkdiseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaaileldde |
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
Spur_hmm316291,hmm468784.AA | Protein | None | 123 | None | Fasta, JSON |
Spur_hmm316291,hmm468784.NA | RNA | None | 369 | None | Fasta, JSON |
Spur_hmm316291,hmm468784.AA.PD_1-123 | Protein Phosphatase Domain | None | 123 | None | Fasta, JSON |