SPU_011110
Species: S.purpuratus
Alias: SPU_011110
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP1C
Protein domain

Protein domains of SPU_011110 .AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase SPU_011110 .AA Subfamily.PPP1C.PD 1-166 74 7.4e-97 314.0 In-house 104-269 (271) Show / Hide
Range on Protein: 1-166
Range on HMM: 104-269/271
Sequence Identity: 74% (123 aa)

IYGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVV
||||||||||||||||||||.|||||||.||.|. .|||.||||||||....|.|.|.|| |.||.||.|||||.|||....||||||||||.||| |||
iygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfgadvv

RHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQV
..||||..|.|||||||||||||.||.||.|||||||||||||||||..|| |...| |||.||..
ekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkp

Phosphatase SPU_011110 .AA Family.PPP.PD 1-166 53 5.4e-77 249.2 In-house 172-338 (349) Show / Hide
Range on Protein: 1-166
Range on HMM: 172-338/349
Sequence Identity: 53% (89 aa)

IYGFYDECKRRY--NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGD
.||||.|.|..|  . .....|...||.||.||.....|.|.||||||.|...||.|.| |||..|..||.|||||.|| |.  || .|.|||...|| |
vygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp-eeqkgwkpnkRGvgfvFgpd

VVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQV
.|..|||||.|.||.|||.|||.||.||..|||||.|||||||||..|.| |. |...|..|..... 
avekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkp

Phosphatase SPU_011110 .AA Group.PPP.PD 1-166 53 5.4e-77 249.2 In-house 172-338 (349) Show / Hide
Range on Protein: 1-166
Range on HMM: 172-338/349
Sequence Identity: 53% (89 aa)

IYGFYDECKRRY--NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGD
.||||.|.|..|  . .....|...||.||.||.....|.|.||||||.|...||.|.| |||..|..||.|||||.|| |.  || .|.|||...|| |
vygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp-eeqkgwkpnkRGvgfvFgpd

VVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQV
.|..|||||.|.||.|||.|||.||.||..|||||.|||||||||..|.| |. |...|..|..... 
avekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkp

Phosphatase SPU_011110 .AA Subfamily.PPP_Nematode_6.PD 1-165 54 1.5e-74 240.4 In-house 104-269 (272) Show / Hide
Range on Protein: 1-165
Range on HMM: 104-269/272
Sequence Identity: 54% (91 aa)

IYGFYDECKRRYN-IKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDV
.||||||..|||.  .|...| ..|| ||..|.| | |.|||||||. |...||||...|||| ... |  ||||.||.. ..|| || ||||..|| |.
vyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGeda

VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ
|...|.| .. |..||||||.|||.|| ..||||.||||.|||.|||||.|| | ..|..||..|.
vkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlk

Phosphatase SPU_011110 .AA Subfamily.PPP_Nematode_3.PD 2-165 53 9.7e-72 231.6 In-house 142-305 (308) Show / Hide
Range on Protein: 2-165
Range on HMM: 142-305/308
Sequence Identity: 53% (88 aa)

YGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVVR
|||| |.|.||. .|...|   ||.||..|||. .|.|||||.| .| ...|| .. ||||||| |...|| |||||....|. |  || .  || . |.
yGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavk

HFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ
.|||| .| |.|||||||||||.||. |||||.||||.|||..||.| |. | ..| .|...|.
eflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvdkklvisltvlr

Phosphatase SPU_011110 .AA Subfamily.PPP_Nematode_4.PD 1-162 51 1.4e-62 201.4 In-house 104-265 (271) Show / Hide
Range on Protein: 1-162
Range on HMM: 104-265/271
Sequence Identity: 51% (82 aa)

IYGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVV
.||||.||. .| ..|| .|  ||| |||.|..   ..||||||||.|  .|.|| | .|.. .| ||. ||||||||...| .  ||.||||| .|| .
kygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgvv

RHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFS
  |. |. ||.|||||| |||. .  |||.|.||.||||  | ||| |. . ..|  |.   
edvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislv

Phosphatase SPU_011110 .AA Subfamily.PPP2C.PD 1-162 50 2.5e-59 190.7 In-house 104-265 (271) Show / Hide
Range on Protein: 1-162
Range on HMM: 104-265/271
Sequence Identity: 50% (80 aa)

IYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDeDITGWGENDRGVSYTFGGDV
.||||||| |.| | ..|| ||| |..||..|.|.. |||.|||||| .. .|..|.. |  ..|  | .|||||.||| | .|||   |||||| |. .
vygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpd-drggwgisprgagytfgkdi

VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFS
.| |.|.|.|. ||||.| .||.. ..|..||.|||||||    | |... . ..|. ||   
seefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysfl

Phosphatase SPU_011110 .AA Subfamily.PPP4C.PD 1-165 45 2.7e-59 190.6 In-house 104-268 (271) Show / Hide
Range on Protein: 1-165
Range on HMM: 104-268/271
Sequence Identity: 45% (74 aa)

IYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGDV
.||||||| |.| ....|.  |. |. |..||...| |||.||||||.....|..| | |  ..|..| .|||||.|| ||..||.   ||| || ||| 
vygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdp-edaegwavsprgagylfgsdv

VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ
.| ..|...||.||||.| .||..  ..|..|..||||||    | | .. . ..|   |.|..  
veqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife

Phosphatase SPU_011110 .AA Subfamily.PPP6C.PD 1-163 44 2.4e-55 177.5 In-house 104-266 (271) Show / Hide
Range on Protein: 1-163
Range on HMM: 104-266/271
Sequence Identity: 44% (72 aa)

IYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGDV
.|||||||...| | . || .|. |. |.|||.... ..|.|||||||.. .||.| |.|  .|| .| .|||.|.|| ||.  |   .||| ||  |..
vygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdp-edvetwavsprgagylfgskv

VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSI
.|.. |.|.||.||||.||.|.... . ||||..||||||    | | .... .. . .. .  
tkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereakl

Phosphatase SPU_011110 .AA Subfamily.PPP_Nematode_5.PD 2-165 45 1.6e-52 168.1 In-house 105-271 (274) Show / Hide
Range on Protein: 2-165
Range on HMM: 105-271/274
Sequence Identity: 45% (74 aa)

YGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDI--PDHGLVCDLLWADPDEDITGWGEND-RGVSYTFGGD
|||..| |.... .|.|.| | |. ||. | |.  |.|||||.||.|. .|.|. ...|      |.||. |||||||..|.   |  |..|  ||  .|
ygfkeelkkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkk

VVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ
 ..||| ...||||||.|.|.||.|. ...|||.|||| |.||  | . |. |.. |  |||.    
evddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlk

Phosphatase SPU_011110 .AA Subfamily.PPP5C.PD 1-161 42 2.6e-51 164.4 In-house 178-339 (346) Show / Hide
Range on Protein: 1-161
Range on HMM: 178-339/346
Sequence Identity: 42% (70 aa)

IYGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGL-SPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEdITGWGENDRGVSYTFGGDV
.||| .|.| .|. |. . ||. || ||.| |..  .. .|||| | |  ..|.||.|.|  . |..||...|||.||.|  .| ..  |||. .|| ||
lyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqe-anGrspskrGvgiqfGpdv

VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIV-TQDLTCSF
 ..|||.|.|.||.|.|.| |.||.. .. ||.|.||||||| . .| .... . ..||.  |
tkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkf

Phosphatase SPU_011110 .AA Subfamily.PPP_Nematode_2.PD 2-155 39 7.3e-51 162.6 In-house 108-269 (281) Show / Hide
Range on Protein: 2-155
Range on HMM: 108-269/281
Sequence Identity: 39% (64 aa)

YGFYDECKRRYNI---KLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDE-DITGWGENDRGVSYTFGG
|||.|||. .||    | |. . |.||.||.||.. . ..|.|||.|| |...... .| ||| .| .|| |||||.||... .||.   ||.|..|.  
ygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfdd

DVVRHFLKKNELSLIVRAHQVVE----DGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQ
|| .| ..|.|.|.|||||...    .|...  . .||.|||| || .  .... . .  . 
ivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsmkndssvlkleev

Phosphatase SPU_011110 .AA Subfamily.PPP3C.PD 3-156 35 5.5e-45 143.7 In-house 106-272 (292) Show / Hide
Range on Protein: 3-156
Range on HMM: 106-272/292
Sequence Identity: 35% (59 aa)

GFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDI------TGWGEN-DRGVSYTF
| .|.| .|. .........|..||.||....  .|.||||||.....|..... |  ..| .| .|||||.|| ||         . .||| || ..  
tfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcsyfy

GGDVVRHFLKKNELSLIVRAHQVVEDGYQFFQK------RKLVTLFSAPNYCGEFDNAAGVMIVTQD
 | .||.||.|  |.|||.. ..||. ..|        |.||||||||.. ..| | |. ....   
sykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyenn

Phosphatase SPU_011110 .AA Subfamily.PPP_Nematode_7.PD 13-165 36 1.2e-39 126.0 In-house 131-293 (296) Show / Hide
Range on Protein: 13-165
Range on HMM: 131-293/296
Sequence Identity: 36% (58 aa)

NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPL-DIPDHGLVCDLLWADP--------DEDITGWGEN-DRGVSYTFGGDVVRH
.... | ..|  .|.||.|   |.|.|||.|| |. ......|.||| .. .  |. |||.|||         .. . ..|  ||.|..|.   |... .
gkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqllaavsekpkyeknevrglsvvfneaaved

FLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ
|..|.||||||| .  |..||...||.|.||||.| .|.||   |. |. .   | ..|.   
vCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslr

Phosphatase SPU_011110 .AA PP2Ac 1-168 28 5.2e-37 130.18 SMART 1-321 (321) Show / Hide
Range on Protein: 1-168
Range on HMM: 1-321/321
Sequence Identity: 28% (91 aa)

I---------------------------------------------------------------------------------------------------
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MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

---------------YGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSP------DLNQVDQLRHISR----PLDIPDHGLVCDLLWA
               |||||||||.| . ..|| |..||...|..|.. ..|.||||||||      ...  |..| | |    |...||.|| |||||.
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP--------DEDITGWGEND-RGVSYTFGGDVVRHFLKKNELSLIVRAHQVVE----DGYQFFQKR-----KLVTLFSAPNYCGEFDNAAGVMIV----
||        | .  ||. |  ||.||.|| |||. |.||| |.||.||||.|.    |||.|...|     ||.|.|||||||...||.| || |    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------TQDLTCSFSILQVS*
        .| |.|  ..   
VIQYKMDKNLKCHFVQFKPQM

Phosphatase SPU_011110 .AA Subfamily.PPP7C.PD 69-161 35 5.6e-20 61.2 In-house 239-331 (338) Show / Hide
Range on Protein: 69-161
Range on HMM: 239-331/338
Sequence Identity: 35% (32 aa)

VCDLLWADPDEDITGWGENDRGVSYTFGGDVVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSF
. |.||.|| ..   . .  ||    || || ...|.| .|.|..|.|.   .||.|  ..|..|.||| ||  |  |    . ...|||.  
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltpri

Phosphatase SPU_011110 .AA Subfamily.PPP_Nematode_1.PD 25-165 25 3.5e-15 45.9 In-house 133-268 (273) Show / Hide
Range on Protein: 25-165
Range on HMM: 133-268/273
Sequence Identity: 25% (35 aa)

NCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDiTGWGENDrgvsyTFGG-DVVRHFLKKNELSLIVRAHQVVEDGY
. ||.|||..  ......|.|. . . ...  . |     .|    .. . | |   .   |||      ..   .|.. ||..|...|...|| .||.|
krlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-sPvtend-----idekskivkellkatdmsvmirsnsvvreGy

QFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ
  | .|.||.||...  ...|   |. . .||  .|  ..  
lftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie

Phosphatase SPU_011110 .AA Metallophos 2-120 16 7.3e-11 41.99 Pfam 76-124 (124) Show / Hide
Range on Protein: 2-120
Range on HMM: 76-124/124
Sequence Identity: 16% (20 aa)

YGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVVR
|||| |       ..| .. ..| ..| | .....|.||||..                                                         
YGFY-E-------NDW-MWWWWF-WMPLA-LDDWKILCMHGPP---------------------------------------------------------

HFLKKNELSLIVRAHQVVE
 |.| |.. ...|.|. |.
-FCK-NGVDYVIRGHTHVP

Phosphatase SPU_011110 .AA Subfamily.PPP7C.PD 2-59 32 8e-10 27.8 In-house 146-205 (338) Show / Hide
Range on Protein: 2-59
Range on HMM: 146-205/338
Sequence Identity: 32% (20 aa)

YGFYDECKRRY---NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSpDLNQVDQLRHISR
|||  | . .|   . |. ... | |  ||.|....  |. .|||.| |  ... | .|.|
yGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis-dktdlelldkier

Sequence
Name Sequence Type Origin Length Description Download
SPU_011110 .AA Protein None 187 None Fasta, JSON
SPU_011110 .NA RNA None 561 None Fasta, JSON
SPU_011110 .AA.PD_1-168 Protein Phosphatase Domain None 168 None Fasta, JSON