Gene SPU_011110
SPU_011110
Species: S.purpuratus
Alias: SPU_011110
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of SPU_011110 .AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | SPU_011110 .AA | Subfamily.PPP1C.PD | 1-166 | 74 | 7.4e-97 | 314.0 | In-house | 104-269 (271) | Show / Hide |
Range on Protein: 1-166 Range on HMM: 104-269/271 Sequence Identity: 74% (123 aa) IYGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVV ||||||||||||||||||||.|||||||.||.|. .|||.||||||||....|.|.|.|| |.||.||.|||||.|||....||||||||||.||| ||| iygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfgadvv RHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQV ..||||..|.|||||||||||||.||.||.|||||||||||||||||..|| |...| |||.||.. ekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkp |
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| Phosphatase | SPU_011110 .AA | Family.PPP.PD | 1-166 | 53 | 5.4e-77 | 249.2 | In-house | 172-338 (349) | Show / Hide |
Range on Protein: 1-166 Range on HMM: 172-338/349 Sequence Identity: 53% (89 aa) IYGFYDECKRRY--NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGD .||||.|.|..| . .....|...||.||.||.....|.|.||||||.|...||.|.| |||..|..||.|||||.|| |. || .|.|||...|| | vygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp-eeqkgwkpnkRGvgfvFgpd VVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQV .|..|||||.|.||.|||.|||.||.||..|||||.|||||||||..|.| |. |...|..|..... avekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkp |
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| Phosphatase | SPU_011110 .AA | Group.PPP.PD | 1-166 | 53 | 5.4e-77 | 249.2 | In-house | 172-338 (349) | Show / Hide |
Range on Protein: 1-166 Range on HMM: 172-338/349 Sequence Identity: 53% (89 aa) IYGFYDECKRRY--NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGD .||||.|.|..| . .....|...||.||.||.....|.|.||||||.|...||.|.| |||..|..||.|||||.|| |. || .|.|||...|| | vygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp-eeqkgwkpnkRGvgfvFgpd VVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQV .|..|||||.|.||.|||.|||.||.||..|||||.|||||||||..|.| |. |...|..|..... avekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkp |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP_Nematode_6.PD | 1-165 | 54 | 1.5e-74 | 240.4 | In-house | 104-269 (272) | Show / Hide |
Range on Protein: 1-165 Range on HMM: 104-269/272 Sequence Identity: 54% (91 aa) IYGFYDECKRRYN-IKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDV .||||||..|||. .|...| ..|| ||..|.| | |.|||||||. |...||||...|||| ... | ||||.||.. ..|| || ||||..|| |. vyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGeda VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ |...|.| .. |..||||||.|||.|| ..||||.||||.|||.|||||.|| | ..|..||..|. vkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlk |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP_Nematode_3.PD | 2-165 | 53 | 9.7e-72 | 231.6 | In-house | 142-305 (308) | Show / Hide |
Range on Protein: 2-165 Range on HMM: 142-305/308 Sequence Identity: 53% (88 aa) YGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVVR |||| |.|.||. .|...| ||.||..|||. .|.|||||.| .| ...|| .. ||||||| |...|| |||||....|. | || . || . |. yGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavk HFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ .|||| .| |.|||||||||||.||. |||||.||||.|||..||.| |. | ..| .|...|. eflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvdkklvisltvlr |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP_Nematode_4.PD | 1-162 | 51 | 1.4e-62 | 201.4 | In-house | 104-265 (271) | Show / Hide |
Range on Protein: 1-162 Range on HMM: 104-265/271 Sequence Identity: 51% (82 aa) IYGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVV .||||.||. .| ..|| .| ||| |||.|.. ..||||||||.| .|.|| | .|.. .| ||. ||||||||...| . ||.||||| .|| . kygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgvv RHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFS |. |. ||.|||||| |||. . |||.|.||.|||| | ||| |. . ..| |. edvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislv |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP2C.PD | 1-162 | 50 | 2.5e-59 | 190.7 | In-house | 104-265 (271) | Show / Hide |
Range on Protein: 1-162 Range on HMM: 104-265/271 Sequence Identity: 50% (80 aa) IYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDeDITGWGENDRGVSYTFGGDV .||||||| |.| | ..|| ||| |..||..|.|.. |||.|||||| .. .|..|.. | ..| | .|||||.||| | .||| |||||| |. . vygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpd-drggwgisprgagytfgkdi VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFS .| |.|.|.|. ||||.| .||.. ..|..||.||||||| | |... . ..|. || seefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysfl |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP4C.PD | 1-165 | 45 | 2.7e-59 | 190.6 | In-house | 104-268 (271) | Show / Hide |
Range on Protein: 1-165 Range on HMM: 104-268/271 Sequence Identity: 45% (74 aa) IYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGDV .||||||| |.| ....|. |. |. |..||...| |||.||||||.....|..| | | ..|..| .|||||.|| ||..||. ||| || ||| vygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdp-edaegwavsprgagylfgsdv VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ .| ..|...||.||||.| .||.. ..|..|..|||||| | | .. . ..| |.|.. veqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP6C.PD | 1-163 | 44 | 2.4e-55 | 177.5 | In-house | 104-266 (271) | Show / Hide |
Range on Protein: 1-163 Range on HMM: 104-266/271 Sequence Identity: 44% (72 aa) IYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPdEDITGWGENDRGVSYTFGGDV .|||||||...| | . || .|. |. |.|||.... ..|.|||||||.. .||.| |.| .|| .| .|||.|.|| ||. | .||| || |.. vygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdp-edvetwavsprgagylfgskv VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSI .|.. |.|.||.||||.||.|.... . ||||..|||||| | | .... .. . .. . tkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereakl |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP_Nematode_5.PD | 2-165 | 45 | 1.6e-52 | 168.1 | In-house | 105-271 (274) | Show / Hide |
Range on Protein: 2-165 Range on HMM: 105-271/274 Sequence Identity: 45% (74 aa) YGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDI--PDHGLVCDLLWADPDEDITGWGEND-RGVSYTFGGD |||..| |.... .|.|.| | |. ||. | |. |.|||||.||.|. .|.|. ...| |.||. |||||||..|. | |..| || .| ygfkeelkkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkk VVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ ..||| ...||||||.|.|.||.|. ...|||.|||| |.|| | . |. |.. | |||. evddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlk |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP5C.PD | 1-161 | 42 | 2.6e-51 | 164.4 | In-house | 178-339 (346) | Show / Hide |
Range on Protein: 1-161 Range on HMM: 178-339/346 Sequence Identity: 42% (70 aa) IYGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGL-SPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEdITGWGENDRGVSYTFGGDV .||| .|.| .|. |. . ||. || ||.| |.. .. .|||| | | ..|.||.|.| . |..||...|||.||.| .| .. |||. .|| || lyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqe-anGrspskrGvgiqfGpdv VRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIV-TQDLTCSF ..|||.|.|.||.|.|.| |.||.. .. ||.|.||||||| . .| .... . ..||. | tkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkf |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP_Nematode_2.PD | 2-155 | 39 | 7.3e-51 | 162.6 | In-house | 108-269 (281) | Show / Hide |
Range on Protein: 2-155 Range on HMM: 108-269/281 Sequence Identity: 39% (64 aa) YGFYDECKRRYNI---KLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDE-DITGWGENDRGVSYTFGG |||.|||. .|| | |. . |.||.||.||.. . ..|.|||.|| |...... .| ||| .| .|| |||||.||... .||. ||.|..|. ygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfdd DVVRHFLKKNELSLIVRAHQVVE----DGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQ || .| ..|.|.|.|||||... .|... . .||.|||| || . .... . . . ivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsmkndssvlkleev |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP3C.PD | 3-156 | 35 | 5.5e-45 | 143.7 | In-house | 106-272 (292) | Show / Hide |
Range on Protein: 3-156 Range on HMM: 106-272/292 Sequence Identity: 35% (59 aa) GFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDI------TGWGEN-DRGVSYTF | .|.| .|. .........|..||.||.... .|.||||||.....|..... | ..| .| .|||||.|| || . .||| || .. tfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcsyfy GGDVVRHFLKKNELSLIVRAHQVVEDGYQFFQK------RKLVTLFSAPNYCGEFDNAAGVMIVTQD | .||.||.| |.|||.. ..||. ..| |.||||||||.. ..| | |. .... sykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyenn |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP_Nematode_7.PD | 13-165 | 36 | 1.2e-39 | 126.0 | In-house | 131-293 (296) | Show / Hide |
Range on Protein: 13-165 Range on HMM: 131-293/296 Sequence Identity: 36% (58 aa) NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPL-DIPDHGLVCDLLWADP--------DEDITGWGEN-DRGVSYTFGGDVVRH .... | ..| .|.||.| |.|.|||.|| |. ......|.||| .. . |. |||.||| .. . ..| ||.|..|. |... . gkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqllaavsekpkyeknevrglsvvfneaaved FLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ |..|.||||||| . |..||...||.|.||||.| .|.|| |. |. . | ..|. vCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslr |
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| Phosphatase | SPU_011110 .AA | PP2Ac | 1-168 | 28 | 5.2e-37 | 130.18 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 1-168
Range on HMM: 1-321/321
Sequence Identity: 28% (91 aa)
I---------------------------------------------------------------------------------------------------
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MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
---------------YGFYDECKRRY-NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSP------DLNQVDQLRHISR----PLDIPDHGLVCDLLWA
|||||||||.| . ..|| |..||...|..|.. ..|.|||||||| ... |..| | | |...||.|| |||||.
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
DP--------DEDITGWGEND-RGVSYTFGGDVVRHFLKKNELSLIVRAHQVVE----DGYQFFQKR-----KLVTLFSAPNYCGEFDNAAGVMIV----
|| | . ||. | ||.||.|| |||. |.||| |.||.||||.|. |||.|...| ||.|.|||||||...||.| || |
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
------TQDLTCSFSILQVS*
.| |.| ..
VIQYKMDKNLKCHFVQFKPQM
|
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP7C.PD | 69-161 | 35 | 5.6e-20 | 61.2 | In-house | 239-331 (338) | Show / Hide |
Range on Protein: 69-161 Range on HMM: 239-331/338 Sequence Identity: 35% (32 aa) VCDLLWADPDEDITGWGENDRGVSYTFGGDVVRHFLKKNELSLIVRAHQVVEDGYQFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSF . |.||.|| .. . . || || || ...|.| .|.|..|.|. .||.| ..|..|.||| || | | . ...|||. ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltpri |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP_Nematode_1.PD | 25-165 | 25 | 3.5e-15 | 45.9 | In-house | 133-268 (273) | Show / Hide |
Range on Protein: 25-165 Range on HMM: 133-268/273 Sequence Identity: 25% (35 aa) NCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDiTGWGENDrgvsyTFGG-DVVRHFLKKNELSLIVRAHQVVEDGY . ||.|||.. ......|.|. . . ... . | .| .. . | | . ||| .. .|.. ||..|...|...|| .||.| krlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-sPvtend-----idekskivkellkatdmsvmirsnsvvreGy QFFQKRKLVTLFSAPNYCGEFDNAAGVMIVTQDLTCSFSILQ | .|.||.||... ...| |. . .|| .| .. lftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie |
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| Phosphatase | SPU_011110 .AA | Metallophos | 2-120 | 16 | 7.3e-11 | 41.99 | Pfam | 76-124 (124) | Show / Hide |
Range on Protein: 2-120 Range on HMM: 76-124/124 Sequence Identity: 16% (20 aa) YGFYDECKRRYNIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSPDLNQVDQLRHISRPLDIPDHGLVCDLLWADPDEDITGWGENDRGVSYTFGGDVVR |||| | ..| .. ..| ..| | .....|.||||.. YGFY-E-------NDW-MWWWWF-WMPLA-LDDWKILCMHGPP--------------------------------------------------------- HFLKKNELSLIVRAHQVVE |.| |.. ...|.|. |. -FCK-NGVDYVIRGHTHVP |
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| Phosphatase | SPU_011110 .AA | Subfamily.PPP7C.PD | 2-59 | 32 | 8e-10 | 27.8 | In-house | 146-205 (338) | Show / Hide |
Range on Protein: 2-59 Range on HMM: 146-205/338 Sequence Identity: 32% (20 aa) YGFYDECKRRY---NIKLWKTFTDCFNCLPIAAVVEGTIFCMHGGLSpDLNQVDQLRHISR ||| | . .| . |. ... | | ||.|.... |. .|||.| | ... | .|.| yGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis-dktdlelldkier |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| SPU_011110 .AA | Protein | None | 187 | None | Fasta, JSON |
| SPU_011110 .NA | RNA | None | 561 | None | Fasta, JSON |
| SPU_011110 .AA.PD_1-168 | Protein Phosphatase Domain | None | 168 | None | Fasta, JSON |