Gene SPU_012785
SPU_012785
Species: S.purpuratus
Alias: SPU_012785
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of SPU_012785 .AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | SPU_012785 .AA | Family.PPP.PD | 19-131 | 50 | 5.3e-51 | 163.7 | In-house | 58-171 (349) | Show / Hide |
Range on Protein: 19-131 Range on HMM: 58-171/349 Sequence Identity: 50% (57 aa) VRSTPGKQVQLPENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDS-NYLFLGDYVDRGKQSLETICLMLAYKLKYPNNF . . .. ||..... |.. .| . .||.|.|.|||....||||||. ||.| ||..|.||.. .||||||||||||.|.|.|.|..|.||.||..| lveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrf FLLRGNHECASINR ||||||||..|.|. fllRGnhEsrsvnk |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP1C.PD | 29-131 | 76 | 7.9e-58 | 186.0 | In-house | 1-103 (271) | Show / Hide |
Range on Protein: 29-131 Range on HMM: 1-103/271 Sequence Identity: 76% (79 aa) LPENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECAS | |..||.||. .|| ||..|.|.|||||..||||||||| ||.|.|.|.||||.||||||||||||||||||||.|.||||.|||.||||||||||||| lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas INR ||| inr |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_6.PD | 31-131 | 66 | 2.3e-51 | 164.4 | In-house | 3-103 (272) | Show / Hide |
Range on Protein: 31-131 Range on HMM: 3-103/272 Sequence Identity: 66% (67 aa) ENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASIN |... .|..|... | ....|||.|||... ||||||| ||.| |||.|||||.||||||||||||.||||.|.|.||||.|.|||||||||||||..|| eeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceain R | r |
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| Phosphatase | SPU_012785 .AA | Group.PPP.PD | 19-131 | 50 | 5.3e-51 | 163.7 | In-house | 58-171 (349) | Show / Hide |
Range on Protein: 19-131 Range on HMM: 58-171/349 Sequence Identity: 50% (57 aa) VRSTPGKQVQLPENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDS-NYLFLGDYVDRGKQSLETICLMLAYKLKYPNNF . . .. ||..... |.. .| . .||.|.|.|||....||||||. ||.| ||..|.||.. .||||||||||||.|.|.|.|..|.||.||..| lveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrf FLLRGNHECASINR ||||||||..|.|. fllRGnhEsrsvnk |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_5.PD | 33-131 | 47 | 1.5e-38 | 122.2 | In-house | 5-103 (274) | Show / Hide |
Range on Protein: 33-131 Range on HMM: 5-103/274 Sequence Identity: 47% (47 aa) QIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASINR .| .. . ... . |.|.|||..||||||||..||.| |...| .|. .||||||||||| .||| . |....|..||.. |||||||. ||. dilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkink |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_4.PD | 33-131 | 46 | 2.8e-35 | 111.9 | In-house | 5-103 (271) | Show / Hide |
Range on Protein: 33-131 Range on HMM: 5-103/271 Sequence Identity: 46% (46 aa) QIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASINR .| . ..... | .| |||.|||. .|||.|.|. |||| || | .|. ..|||||||||.|..|.. |....|..|... .||||||| ||.|. eiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnk |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP3C.PD | 31-129 | 44 | 4.9e-35 | 111.0 | In-house | 3-101 (292) | Show / Hide |
Range on Protein: 31-129 Range on HMM: 3-101/292 Sequence Identity: 44% (44 aa) ENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASI |... .. . . . . .|. |.|.|||. ..||||||. ||.. |. | | ...||||||||||| |.|.. ..| |..||...||||||||| . eesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhl |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP4C.PD | 31-130 | 47 | 6.6e-35 | 110.6 | In-house | 3-102 (271) | Show / Hide |
Range on Protein: 31-130 Range on HMM: 3-102/271 Sequence Identity: 47% (47 aa) ENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASIN |.....||. .|| ..|| . ....|| . ||||||. ||.. |. | |. |||||||.||||. |.||. |.||.|..||.. |.|||||. .| eeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqit |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_7.PD | 32-130 | 44 | 2.3e-33 | 105.4 | In-house | 4-113 (296) | Show / Hide |
Range on Protein: 32-130 Range on HMM: 4-113/296 Sequence Identity: 44% (48 aa) NQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHF----------DKCGFP-PDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLL |.. |.. |.| .| .|.|. .|| ||||||||| ||.| .| ... . ..|||||||||..|.||.|..|.|. ||....||| nellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyill RGNHECASIN ||||. .|| rGnhetkain |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_2.PD | 32-126 | 50 | 3.2e-33 | 104.7 | In-house | 4-101 (281) | Show / Hide |
Range on Protein: 32-126 Range on HMM: 4-101/281 Sequence Identity: 50% (48 aa) NQIRHLCQLSREQFLEEPMLVELEA---PVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHEC ..|| ... ... ||| . |.... ||..|.|.|||..|| | | . |. |.|||||||||||.||.|...|.||||.||. |||||||| eeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhed |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP6C.PD | 29-130 | 49 | 3.7e-33 | 104.8 | In-house | 1-102 (271) | Show / Hide |
Range on Protein: 29-130 Range on HMM: 1-102/271 Sequence Identity: 49% (50 aa) LPENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECAS ||||....||.| . .||| .. ...|| ..||||||. || | . | ||..|.||||.|||| ||||. ..|. |.|||.. |||||||. lpenelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq IN | it |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP2C.PD | 29-129 | 44 | 3.2e-31 | 98.5 | In-house | 1-101 (271) | Show / Hide |
Range on Protein: 29-129 Range on HMM: 1-101/271 Sequence Identity: 44% (45 aa) LPENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECAS | |.....||. ..| . .| . |...|| ..||.|||. ||. | | ||.||||.||||||| |.||..|..| |..|.. .|||||| leeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrq I | i |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_1.PD | 38-127 | 38 | 3.8e-27 | 85.2 | In-house | 7-99 (273) | Show / Hide |
Range on Protein: 38-127 Range on HMM: 7-99/273 Sequence Identity: 38% (35 aa) CQLSRE--QFLEEPMLVE-LEAPVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECA ..| . ...||. |.| .||.|...||| ..|.|| . . .|.|.. .||||. .| || |||.. ..| | ||.|...|||..| selledalkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyete |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP5C.PD | 25-131 | 41 | 1.1e-26 | 83.4 | In-house | 66-177 (346) | Show / Hide |
Range on Protein: 25-131 Range on HMM: 66-177/346 Sequence Identity: 41% (47 aa) KQVQLPENQIRHLCQLSREQFLEEPMLVELEAP----VNIVGDIHGQYGDLIRHFDKCGFPPD-SNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFL || .|.. . .. . . | . ..| |||.. | . . ||||||. ||. |.. | | . ||| ||.|||| |.|.| ..|..|| |||.||| kqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhffl LRGNHECASINR ||||| ..|. srGnhesdnmnk |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP7C.PD | 56-130 | 43 | 2.4e-23 | 72.3 | In-house | 68-143 (338) | Show / Hide |
Range on Protein: 56-130 Range on HMM: 68-143/338 Sequence Identity: 43% (32 aa) APVNIVGDIHGQYGDLIRHFDKCGFPPD-SNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASIN |.. ||.||. ||. . | |.| .|.| ||.|||||.|.| .....|. | ||....| ||||| .| kevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyiln |
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| Phosphatase | SPU_012785 .AA | Metallophos | 56-131 | 42 | 1.2e-22 | 85.06 | Pfam | 1-74 (124) | Show / Hide |
Range on Protein: 56-131 Range on HMM: 1-74/124 Sequence Identity: 42% (32 aa) APVNIVGDIHGQYGDLIRHFDKCGFPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASINR ... ..|||||||.||.| |... .. ...|.|||||||..|.|.|.|...||..||......||||.....|. MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGND |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_3.PD | 84-131 | 58 | 1.1e-19 | 60.7 | In-house | 93-140 (308) | Show / Hide |
Range on Protein: 84-131 Range on HMM: 93-140/308 Sequence Identity: 58% (28 aa) SNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLLRGNHECASINR ..||||||||||| |.| . |..|.||.||.. |||||||| ..|. kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvnt |
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| Phosphatase | SPU_012785 .AA | Subfamily.PPP_Nematode_3.PD | 31-82 | 52 | 3.8e-16 | 49.0 | In-house | 3-54 (308) | Show / Hide |
Range on Protein: 31-82 Range on HMM: 3-54/308 Sequence Identity: 52% (27 aa) ENQIRHLCQLSREQFLEEPMLVELEAPVNIVGDIHGQYGDLIRHFDKCGFPP |... .|| .||.| .||. .|||||| ||||||||. ||. .| |.| ekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpl |
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| Phosphatase | SPU_012785 .AA | PP2Ac | 29-131 | 18 | 2.6e-10 | -38.78 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 29-131
Range on HMM: 1-321/321
Sequence Identity: 18% (60 aa)
LPENQIRHLCQLSREQFLEEPMLVELE----APVNIVGDIHGQYGDLIRHF---DKCG-FPPDSNYLFLGDYVDRGKQSLETICLMLAYKLKYPNNFFLL
.... |..||. ..| | ||..||.| .|| ..||||||. ||.| | || | .||..||.|||||||||..|.|.|||...||..||||||||
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
RGNHECASIN------------------------------------------------------------------------------------------
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RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
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DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
--------------------R
VIQYKMDKNLKCHFVQFKPQM
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| SPU_012785 .AA | Protein | None | 131 | None | Fasta, JSON |
| SPU_012785 .NA | RNA | None | 393 | None | Fasta, JSON |
| SPU_012785 .AA.PD_29-131 | Protein Phosphatase Domain | None | 103 | None | Fasta, JSON |