• Phosphatome.Net

Gene PPP2CA_spur

PPP2CA_spur
Species: S.purpuratus
Alias: PPP2CA_spur
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP2C
Protein domain

Protein domains of PPP2CA_spur.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PPP2CA_spur.AA Subfamily.PPP7C.PD 5-184 33 1.3e-38 122.4 In-house 20-205 (338) Show / Hide 
Range on Protein: 5-184
Range on HMM: 20-205/338
Sequence Identity: 33% (62 aa)

STKDLDIEIEQLNDCKQLQENQVKHLCEMAKEILTKESNVQEVKC----PVTVCGDVHGQFHDLME-LFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLL
...|..  .|...  |.|  . | ..   .|..| .  |...|.      ||||||.||...||.  |.. |  |.. .|.| ||.||||||| . .|..
llddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillil

VCLKVRYRERITILRGNHESRQITQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDtLDHIRALDR
| . | . . . |||||   .   |||  |   ||   .... . . |.| .|||..|.| .|. .|||.| . | |. ...|    
falllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktd-lelldkier
Phosphatase PPP2CA_spur.AA Subfamily.PPP2C.PD 22-292 91 2.1e-188 614.0 In-house 1-271 (271) Show / Hide 
Range on Protein: 22-292
Range on HMM: 1-271/271
Sequence Identity: 91% (248 aa)

LQENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQ
|.|..||.|||.|||||.|||||.|||||||||||||||||||.|||||||.||.||||||||||||||||||||||||.|||||.||||||||||||||
leeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrq

ITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQ
||||||||||||||||||||||||||||||||||||||.|||||||||||||||||.||||||.|||||||||||||||||||||||||||||||||||.
itqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgk

DISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDPAP
||||.||..|||||.|||||||||||||.||||||||||||||||||||||||.||||.||||||||||||
diseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpap
Phosphatase PPP2CA_spur.AA PP2Ac 22-292 44 1.9e-158 533.63 SMART 1-321 (321) Show / Hide 
Range on Protein: 22-292
Range on HMM: 1-321/321
Sequence Identity: 44% (143 aa)

LQENQVKHLCEMAKEILTKESNVQEVK----CPVTVCGDVHGQFHDLMELF---RIGG-RSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITIL
.... ...||...|||. .|.|. ||      |||||||.||||.||..||   ...| ..|.|||.|.|||||||..|.|...||.|.|..| .....|
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHESRQIT---QVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSP------SIDTLDHIRALDR----IQEVPHEGPMCDLLWS
|||||.|...   |.||||||| |||.....||.|...|...||.||....|.| ||||||      .| ||| || .||     || |..|.|||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP---------DDRGGWGISP-RGAGYTFGQDISETFNHSNGLTLISRAHQLVM----EGYNWCHDR-----NVVTIFSAPNYCYRCGNQAAIMEL----
||         ..  ||.... ||..|.||.|. . | . |.| || ||||.|.    .|| ..|||      ..|||||||||..|.| ||.|..    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DDALKYSFLQFDPAP
      |. || .| ||.|..
VIQYKMDKNLKCHFVQFKPQM
Phosphatase PPP2CA_spur.AA Subfamily.PPP4C.PD 23-291 68 3.3e-145 472.3 In-house 2-270 (271) Show / Hide 
Range on Protein: 23-291
Range on HMM: 2-270/271
Sequence Identity: 68% (183 aa)

QENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQI
.|..||.||. |.||| .|||||.|..|||||||.||||.||.|||..||  |.|||||.||.||||.|||||  ||..||||| .|||..|||||||||
keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi

TQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQD
|||||||||||||||.|.||.| |..||||.|.|..||.|||.||||||||.|||.||..|| ||||||||.||||||||.|||..||||||| ||.|..
tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsd

ISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDPA
|.||..|...||.||||||||||..  ...|.|..||||||||||| |||.|||..|.. |  |. |  
vveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaa
Phosphatase PPP2CA_spur.AA Subfamily.PPP6C.PD 22-288 60 1.1e-134 437.7 In-house 1-267 (271) Show / Hide 
Range on Protein: 22-288
Range on HMM: 1-267/271
Sequence Identity: 60% (162 aa)

LQENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQ
|.||..|.||.. ...| .||||| |..|||||||.||||.||.|||| ||. |.|.|.|.||.|||||||.||.|.|..||..| .|||.|||||||||
lpenelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq

ITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQ
||||||||||||.||||||.|||.|..|| |...|..|.|..|.|||||| . |||.|| ..| ||.||.|..|||.||||.|   | .||||||| ||.
itqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgs

DISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQF
 ... |.| | | ||.||||||.||...  | ..||..||||||||||| |.|..|.|| . ..  |
kvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereaklf
Phosphatase PPP2CA_spur.AA Family.PPP.PD 6-293 49 7e-132 429.7 In-house 52-341 (349) Show / Hide 
Range on Protein: 6-293
Range on HMM: 52-341/349
Sequence Identity: 49% (143 aa)

TKDLDIEIEQLNDCKQLQENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNT-NYLFMGDYVDRGYYSVETVTLLVCLKV
..  .  .|.... |||....|. |.|.|||.| ||.|..||..|.|||||.||||.||..||.|.|. |.. .|||.|||||||..|||...||..||.
pdlvkelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkl

RYRERITILRGNHESRQITQVYGFYDECLRKYGN-ANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPD
.| .|...||||||||....|||||.|. .|| . ......|...|..|||.||.|..|.|.||||||.. .||.||...| .|.|.||..||||||||.
lypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpe

DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDPAPR
.. ||  ..||.|..||.|. | | . |.| || |||..|.|||.....|..||||||||||....|.||....|..||.|. ||.|...
eqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh
Phosphatase PPP2CA_spur.AA Group.PPP.PD 6-293 49 7e-132 429.7 In-house 52-341 (349) Show / Hide 
Range on Protein: 6-293
Range on HMM: 52-341/349
Sequence Identity: 49% (143 aa)

TKDLDIEIEQLNDCKQLQENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNT-NYLFMGDYVDRGYYSVETVTLLVCLKV
..  .  .|.... |||....|. |.|.|||.| ||.|..||..|.|||||.||||.||..||.|.|. |.. .|||.|||||||..|||...||..||.
pdlvkelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkl

RYRERITILRGNHESRQITQVYGFYDECLRKYGN-ANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPD
.| .|...||||||||....|||||.|. .|| . ......|...|..|||.||.|..|.|.||||||.. .||.||...| .|.|.||..||||||||.
lypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpe

DRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDPAPR
.. ||  ..||.|..||.|. | | . |.| || |||..|.|||.....|..||||||||||....|.||....|..||.|. ||.|...
eqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh
Phosphatase PPP2CA_spur.AA Subfamily.PPP1C.PD 22-288 48 1.7e-103 335.7 In-house 1-267 (271) Show / Hide 
Range on Protein: 22-288
Range on HMM: 1-267/271
Sequence Identity: 48% (130 aa)

LQENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQ
|.|.....||. |.||. ..  . |...|. ..||.|||..||. ||  ||  |..||||.|||||||  |.||..||...|..| |.. .||||||. .
lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

ITQVYGFYDECLRKYgNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGYTFG
|...||||||| |.| | ..|| |.| |. ||..|.|| .|||.||||||.. .|..|| . |  .||..| .|||||||||..  ||| . ||  .|||
inriygfydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfg

QDISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQF
.|. |.| . . | || ||||.| .||.. ..|..||.||||||| .  | .|.| .|. |  ||  .
advvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqil
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_6.PD 23-289 44 7e-98 317.0 In-house 2-269 (272) Show / Hide 
Range on Protein: 23-289
Range on HMM: 2-269/272
Sequence Identity: 44% (118 aa)

QENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQI
.|.....|.|.||....|.. . ||. |..||||.|||. ||. ||  ||  |..||||.||||||| .|.|...||.. ||.. ... .||||||  .|
keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai

TQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDD-RGGWGISPRGAGYTFGQ
 .|||||||. |.| ...... | ..|..||||||| |.|.|.|||||... .||..|.| | .. ..|    |||||||..   ||  . ||....||.
nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe

DISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFD
|  . . ..  . |. ||||.| .||..  ....|||||||.|| .| ||.|..|. |. ||  .   
davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlk
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_4.PD 25-291 42 7.7e-89 287.5 In-house 4-270 (271) Show / Hide 
Range on Protein: 25-291
Range on HMM: 4-270/271
Sequence Identity: 42% (113 aa)

NQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQITQ
.... .  .|..|...|... |.. |. | ||.|.||.||..|| . || |.. ..|.|||||||  ..|.. ||.|||.|||.|| .||||||  .. .
eeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnk

VYGFYDECLRKYGNaNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRG-GWGISPRGAGYTFGQDI
.||||.||  |||. ..|  |   |. ||..||.  ...|.||||||.. .||..|   .  |.. | . ||||.|||... .|  | ||..||||... 
kygfyeecvtkyge-elwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgv

SETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDPA
|   .| .. || ||||.|..||.    |...|.||.||||| ||.. ||..|. |. .. |.     
vedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvpe
Phosphatase PPP2CA_spur.AA Subfamily.PPP5C.PD 12-289 40 1.1e-85 277.5 In-house 60-343 (346) Show / Hide 
Range on Protein: 12-289
Range on HMM: 60-343/346
Sequence Identity: 40% (114 aa)

EIEQLNDCKQLQENQVKHLCEMAKEILTKESNVQEVKCP----VTVCGDVHGQFHDLMELFRIGGR-SPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRY
.|.... |.|..  . ..  .|||.| |.. . |.. |    .|||||.||||.||...|.. |. |..  ||| ||.|||| .|||...|...|. | .
llelfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfklly

RERITILRGNHESRQITQVYGFYDECLRKYgNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSI-DTLDHIRALDRIQEVPHEGPMCDLLWSDPDDR
.. . |||||| .. ..||| .|.  || ...| . ||..|..|||. ... ... .||||  .   |||..| .|| ..|.||....||||||... | 
pnhfflsrGnhesdnmnklyGfegevkaky-tekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqea

GGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMEL-DDALKYSFLQFD
. | || | .|| |... | ..|.|.|| |.|.. .|||.  || ...|.||||||| . ||..|...|.| ||  | .|.    
nGrspskrGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfe
Phosphatase PPP2CA_spur.AA Subfamily.PPP3C.PD 22-279 42 1.2e-84 273.8 In-house 1-271 (292) Show / Hide 
Range on Protein: 22-279
Range on HMM: 1-271/292
Sequence Identity: 42% (114 aa)

LQENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQ
|.|... .. |.| ..| ||... ||. |.||.||.||||.||..|| .||   .|.|||.||||||||.|.|.|  | .||. | .|. .||||||.|.
leeesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrh

ITQVYGFYDECLRKYGNaNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGW--------GISPR
.|. . | .|.  ||.. .|.. ... || |||.||.... .|.|||||| |..|| |..||| .|.|. ||.||||||||.. |           |.||
lteyftfkeevkikyse-evyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvr

GAGYTFGQDISETFNHSNGLTLISRAHQLVMEGYNWCHD------RNVVTIFSAPNYCYRCGNQAAIMELDD
  | ..   . .| ..| |  | |||.   .||.  ..        ..|.||||||.    |.||...... 
GcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyen
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_5.PD 24-290 37 8.6e-77 247.7 In-house 3-272 (274) Show / Hide 
Range on Protein: 24-290
Range on HMM: 3-272/274
Sequence Identity: 37% (99 aa)

ENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQIT
.... .. | .|..|   . . ||. |.|..||.|||..||. .|   |..|...|||.|||||||  |.| . || .||..| ... .|||||| ..| 
dkdilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkin

QVYGFYDECLRKYGnANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQ--EVPHEGPMCDLLWSDPDDRgGWGIS---PRGAGYT
..|||..|  .|..  ...| | |.| .||| | |. .|.|.|||.|| ...|| ..|| . ..|| . ||||.||.     ..     |.    ||.  
klygfkeelkkkrq-eslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd-aktfelnkiraisvv

FGQDISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDP
 . . .  .. || |||... |||..  |. .||.|||| |. .  | .|.. ....|. || .. |     
fGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkp
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_2.PD 32-281 42 9e-76 244.3 In-house 11-270 (281) Show / Hide 
Range on Protein: 32-281
Range on HMM: 11-270/281
Sequence Identity: 42% (106 aa)

EMAKEILTKESNV---QEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQITQVYGF
..||. ... | .   .|   |||| .|.|||. ||. .| | .  ....|||.|||||||  |||.| ||...| .| . ..||||||  . |  |||.
nyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygf

YDECLRKYGN--ANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPD--DRGGWGISPRGAGYTFGQDIS
|||| ||..    ||... | |..|||.||. ....|.|||.|| .. |. |  ..|   |||  ||||||||.  .| ||..| ||  ..|.. . | |
fdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfddivv

ETFNHSNGLTLISRAHQLVME----GYNWCHDRNVVTIFSAPNYCyRCGNQAAIMELDDAL
 . |.| |. |||||. |    |. .  .  .|..||| ||.|..... |.          
ekfcadndldlvvrahqlskemirqghklrangrlvslfsalnyl-smkndssvlkleevk
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_3.PD 76-290 43 4.8e-72 232.6 In-house 92-306 (308) Show / Hide 
Range on Protein: 76-290
Range on HMM: 92-306/308
Sequence Identity: 43% (93 aa)

NTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQITQVYGFYDECLRKYgNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDT
. .|||.||||||| .|.| |.||..||..| .....|||||||| . . |||| |. ..| .|.... |   |  |||.|.|. .|.|.|||.| ..  
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry-saalyeafqlafnvlplcavvnkkilcmhGGiseelld

LDHIRALDRIQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAI
|. . .|.|  ..|  | ..|| |.||| .  |.  |.||||  ||..  . |..   | |. ||||.|..||..  ||..|||||||.|| .  | ||.
lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav

MELDDALKYSFLQFDP
...|. |. |.  . |
lsvdkklvisltvlrp
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_7.PD 23-284 32 1.4e-59 191.4 In-house 2-288 (296) Show / Hide 
Range on Protein: 23-284
Range on HMM: 2-288/296
Sequence Identity: 32% (94 aa)

QENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELF----------RIGGRS-PNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERIT
..|..  |....|| . || .. |.  |||. ||.|||..||. .           .. . |  .. ..|.|||||||..|.| ..|.. ||. | ... 
sknellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyi

ILRGNHESRQITQVYGFYDE---CLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDR-IQEVPHEGPMCDLLWSDPDDRGG
.||||||.. |   |.|  |    | |    .... | . | ..||.|||  .|.|.|||.||...|..|. ..| ..|| ..    |||..|| |  . 
llrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvql

WGISPRGAGYTFGQ--DISETFN--------HSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYS
 .. . . |.. .  ..| .||        . ..| || |||| .||...  |. ..||||||.|    .|. |.....   | |  
laavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangkls
Phosphatase PPP2CA_spur.AA Metallophos 49-244 26 4e-41 147.73 Pfam 1-124 (124) Show / Hide 
Range on Protein: 49-244
Range on HMM: 1-124/124
Sequence Identity: 26% (52 aa)

CPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL
 ....|||.|||..||..||.|. . ......|.|||||||..| |.. ||.|.|..|  .. ..||||........|||| |        |.| .. ..
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWWW

FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVM
| ..||  |.|. |.| ||..                                                         |   ||. .. |.|. |.
F-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_1.PD 29-286 23 5.4e-35 110.9 In-house 8-265 (273) Show / Hide 
Range on Protein: 29-286
Range on HMM: 8-265/273
Sequence Identity: 23% (59 aa)

HLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPNTNYLFMGDYVDRGYYSVETVTLLVCLKVRYRERITILRGNHESRQITQVYGF
| | | .|. . | .. .. .|||.||. ... ||...... |  ..  .||.|. .| | .|.|.. .|.| |. | ...||||..|   .     .. 
elledalkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrl

YDECLRKYGNANVWKYF----TDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRIQEVPHEGPMCDLLWSDPDDRggwgiSPRGAGYTFGQ-DI
|   .. ..| |.        |   ||. |... .......|.|. |   ... |..| ...    .. . | |       ||   .  ...  |     
igelrvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-----sPvtendidekski

SETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFL
 .  .... |....| |||  . . ...|..||...|. ... .|  || .|           
vkellkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfk
Phosphatase PPP2CA_spur.AA Subfamily.PPP7C.PD 194-288 36 1.9e-22 69.3 In-house 239-334 (338) Show / Hide 
Range on Protein: 194-288
Range on HMM: 239-334/338
Sequence Identity: 36% (34 aa)

MCDLLWSDPDDR-GGWGISPRGAGYTFGQDISETFNHSNGLTLISRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQF
. |.|||||  . | .  . ||.|  || |... . .  .|.|. |.|.  .|||...|...|.||||| ||     |. | . | ..|...|.  
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltprivqy
Phosphatase PPP2CA_spur.AA Subfamily.PPP_Nematode_3.PD 23-72 42 2.3e-13 39.9 In-house 2-51 (308) Show / Hide 
Range on Protein: 23-72
Range on HMM: 2-51/308
Sequence Identity: 42% (21 aa)

QENQVKHLCEMAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGG
.|... .||  |.|.. ||    |...|||..||.||||.||. |. . |
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
Sequence
Name Sequence Type Origin Length Description Download
PPP2CA_spur.AA Protein None 308 None Fasta, JSON
PPP2CA_spur.NA RNA None 924 None Fasta, JSON
PPP2CA_spur.AA.PD_22-292 Protein Phosphatase Domain None 271 None Fasta, JSON