MUSCLE (3.8) multiple sequence alignment ScerP022_AA_39-535 ----VVCIGLLLVLVQLAFPSSFALR----SASHKKKNVIFFVTDGMGPASLSMARSFNQ DdisP001_AA_81-550 ---YILTSLAILVTVVLLIVFLLPRGW---EGPKKKTNIIMMIGDGMGPAALTMARVCFH DmelP010_AA_65-475 ----ATSQKIWYDKGIDELNEALRPQ-----DLTYPKNVRIFVIQGIDGRDWAAFRFPTS DmelP004_AA_108-581 ------EQKEWYDQGIDELQKAVSRQ----FNRRRAKNVILFVGDGMGPNTVTAARIL-- DmelP001_AA_75-545 ----------------------VKED----SYQKKARNIIIFIGDGMGISTISAGRIYKG DmelP012_AA_41-469 ---------HWLRQAQSQLRERLARTKDSIADVRQAKNVVMLLGDGLSITTLTAARILKG DmelP008_AA_64-537 ---EEKNAQFWYDLAYEEIAKRLEQPQ---LDKRKAKNVILFLGDGMSLSTVAAARIHKG DmelP006_AA_56-531 -PPEEMDPQYWYNIADEEITKRLQLPQ---PNSQKAKNIIMFLGDGMPLSTVAAARILKG DmelP007_AA_57-529 -PPEEMDPQFWYKLADEEIAKRLQLPQ---PNSDRAKNVIMFLGDGMPISTVTAARILKG DmelP003_AA_60-520 -------NAYWRQQGVQFVQQKLASE----PNKRQAKNVILFLGDGMGVTTTSAARNLLG DmelP009_AA_48-510 ----EETQEFWHSASKKLIREKLEFV----RNTKKAKNIILFLGDGMGLATLAAARSYIG DmelP011_AA_37-522 ----LKSKEFWFHDAQRTLYNKLSTP----PNQYRAKNVIFFLGDGMSVPTVTAGRIFDG DmelP013_AA_62-534 ---EERYAEYWQGLAAQTLDQQLESKLR--LNTQLARNVMLFIGDGMSIPTITAGRVYLG DmelP002_AA_46-516 ----ELDTRFWHDKAQSILADKLAGHKK--LNENRAKNVILFLGDGMSVHTIAATRAFMG DmelP005_AA_41-514 --AEEQQTQYWVDKAQAKLLSKLAEQES--ATTNKAKNVILFLGDGMSVHTVTATRNLLG NvecP001_AA_32-504 --------NQWFKDGVSTVKKHLLQR----PNTKPAKNLIIFVGDGCDINTNTAGRILKG HsapP002_AA_20-492 -PEKEKDPKYWRDQAQETLKYALELQK---LNTNVAKNVIMFLGDGMGVSTVTAARILKG HsapP002_AA_20-492 -PEKEKDPKYWRDQAQETLKYALELQK---LNTNVAKNVIMFLGDGMGVSTVTAARILKG HsapP001_AA_22-493 -PAEEENPAFWNRQAAEALDAAKKLQ----PIQKVAKNLILFLGDGLGVPTVTATRILKG HsapP001_AA_22-493 -PAEEENPAFWNRQAAEALDAAKKLQ----PIQKVAKNLILFLGDGLGVPTVTATRILKG HsapP003_AA_39-511 IPVEEENPDFWNREAAEALGAAKKLQ----PAQTAAKNLIIFLGDGMGVSTVTAARILKG HsapP003_AA_39-511 IPVEEENPDFWNREAAEALGAAKKLQ----PAQTAAKNLIIFLGDGMGVSTVTAARILKG HsapP004_AA_21-493 IPVEEENPDFWNRQAAEALGAAKKLQ----PAQTAAKNLIIFLGDGMGVSTVTAARILKG HsapP004_AA_21-493 IPVEEENPDFWNRQAAEALGAAKKLQ----PAQTAAKNLIIFLGDGMGVSTVTAARILKG SpurP004_AA_38-454 ----GQSPDFWNSQARSSIEQALGLE----VNTKPAKNVIVFVGDGMDVSTVVSSRIRQG SpurP003_AA_27-502 ------DAEFWNQEAQDSLKEAIRLTE---RNVNTAKNIVLFLGDGMSIETLTAARILKG SpurP002_AA_22-490 ------DAAFWNNQARDSIQKALERE----LNIGEAKNIIFFLGDGMSVPTVTAARIRQG SpurP001_AA_29-499 -------APYWNLKGRAAVEEALLRQR---LNVNIAKNIIFFLGDGLDVTTTTAARIRKG *: .:: :* * ScerP022_AA_39-535 H--VNDLPIDDILTLDEH-FIGSSRTRSSDSLVTDSAAGATAFACALKSYNGAIGVDPH- DdisP001_AA_81-550 T--KGESTSQAHLHLDPY-IVGTVKTYSSNSVVTDSAAAATAYASGVKTYNNAVGVDAN- DmelP010_AA_65-475 DASRG----NTNFIWDRFPHLARLKNSCSQQFPCQVASVSRALWLGIPLD------KVPD DmelP004_AA_108-581 -----GVKEEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANV DmelP001_AA_75-545 QYLKHGYGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATAIFSGSKTHYGAIGMDATR DmelP012_AA_41-469 Q-RRGGRGEDAQLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTHSGTVGQSGS- DmelP008_AA_64-537 Q-LKGNTGEEDSLSFEKFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVALGITAAV DmelP006_AA_56-531 Q-RQGNTGEESSLSFERFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAAV DmelP007_AA_57-529 Q-RQGNTGEESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSAAV DmelP003_AA_60-520 -------GEEKSLSFENFPFTGLSKTYSVDKIVPDSACTATAYLCGVKGQEGTIGVNGQV DmelP009_AA_48-510 -------GEELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNAHV DmelP011_AA_37-522 Q-LRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTADV DmelP013_AA_62-534 -------GEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAV DmelP002_AA_46-516 -------DSNKQVFFEKFPYLGLSKTYAVNERTPDSANTATAYLTGVKANYGTIGVNAQV DmelP005_AA_41-514 -------DSAEQVYFEGFPYTGLSKTYCVNRQVADSACTATAYLGGVKANYGTIGVNANV NvecP001_AA_32-504 Q-LKGQVGEKGWLSYEEFPYTGLSKTYTTNRQGSDSAGTANAMFTGVKTRSAMIGVNEEV HsapP002_AA_20-492 Q-LHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAAT HsapP002_AA_20-492 Q-LHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAAT HsapP001_AA_22-493 Q-KNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAA HsapP001_AA_22-493 Q-KNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAA HsapP003_AA_39-511 Q-KKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAA HsapP003_AA_39-511 Q-KKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAA HsapP004_AA_21-493 Q-KKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAA HsapP004_AA_21-493 Q-KKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAA SpurP004_AA_38-454 Q-QAGVEGVSNVLAWDAFPHGGLVKTYSTDAQAADSASTSTAIFGGVKTKDGVLGLDDDA SpurP003_AA_27-502 Q-LAGGLGEDAKLAVEDFPHFGLAKTYSTNKQVPDSAATATAYLCGVKTKTGVLGVDDRV SpurP002_AA_22-490 Q-LKGETGEENILAWETFPHVGLIKTYNTDAQVPDSAGTATAFFSGIKTKSGVVGIDDRV SpurP001_AA_29-499 Q-LAGGMGEEASLHFEHFPHVGLVKTYNTDRQVPDSAGTATAYLCGVKSKFGTLGVDDRV . : . . .. : : : : . ScerP022_AA_39-535 -----------HRPCGTVLEAAKLAGYLTGLVVTTRITDATPASFSSHVDYR-WQEDL-- DdisP001_AA_81-550 -----------GKPAGTIIEAAKKLGMKTGLVVTTRISDATPACYFAHSATR---HDEAF DmelP010_AA_65-475 NQQDCGRLFNATQGPISILRQAQLAGLRTGFVTTQRITG--PTGAALGNANGNFECDESM DmelP004_AA_108-581 PLGNCSASLKEDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGM DmelP001_AA_75-545 SKKNGQ-----QGRVQSVMEWAQKEGKRTGVVTTTRITHATPAATYAHIYDRDWECDTEV DmelP012_AA_41-469 -----------GERVDSVLQWAQRAGKATGVVTTTRLTDASPAGAYAHVSRR----GEEL DmelP008_AA_64-537 SFNNCSGSEDPANQVDSIAAWAQAAGKATGIVTTTTLTHASPSGAYAKTTNRFFESDTDI DmelP006_AA_56-531 EYNNCTASQDPANRLTSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTANRMWECDTDV DmelP007_AA_57-529 NFNNCTASQDPANRLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDV DmelP003_AA_60-520 PRTDCKVMLDESTHVDSIAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEV DmelP009_AA_48-510 KRGDCAAMANETNHVFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVL DmelP011_AA_37-522 ELNDCRGSRLPQNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDV DmelP013_AA_62-534 QFKDCQAQAQAAHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEV DmelP002_AA_46-516 QRGDCVTNS--SSHVQSIGQWAQEAGKWAGLVTTARVTHASPAGVYAHVSERNWEHDGEI DmelP005_AA_41-514 SRYSCDGAANEEDRVLSIAHWAQAAGKDAGLVTTARVTHASPAGVYAHIADRNWENDWEV NvecP001_AA_32-504 VTNKCETLTE-DRKVDSILKLAEEAGMATGFITSMRLTHATPANLYAHSASRYWESDKEM HsapP002_AA_20-492 ERSRCNTTQ--GNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEM HsapP002_AA_20-492 ERSRCNTTQ--GNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEM HsapP001_AA_22-493 RFNQCNTTR--GNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADM HsapP001_AA_22-493 RFNQCNTTR--GNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADM HsapP003_AA_39-511 RFNQCNTTR--GNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADV HsapP003_AA_39-511 RFNQCNTTR--GNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADV HsapP004_AA_21-493 RFNQCNTTR--GNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADV HsapP004_AA_21-493 RFNQCNTTR--GNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADV SpurP004_AA_38-454 KRGDCASAT--GNEVASNLHLAHAEGKATGFVTSDSVTGATVAALYAHSPERDWQSDADI SpurP003_AA_27-502 ERGDCVSSL--GGEVKSILEMAQEAGKSVGFVTTTTLTHASPGALYAKVPDRKWQSDMDI SpurP002_AA_22-490 EYADCESGL--GGEVDSVLVNAHNIGKATGVISTARITHATPAATYAHVAKRDWEVDTEM SpurP001_AA_29-499 ERGKCTSIE--GAAVDSILIDSMKAGKSTGLVSTARVTHASPAALYAHTPDRRWENDHDL : : . .*.: : : ScerP022_AA_39-535 ---------------IATHQLG-EYPLGRVVDLLMGGGRSHFYPQGEKASP--------- DdisP001_AA_81-550 ---------------IIDQLL------DKEIDVILGGGKQFFSNKTLQDA---------- DmelP010_AA_65-475 -PLNS---IKSGCQDIAQQLI--SDETGKFLNVLIGGGRQ-MLSSLVPNTK------YDP DmelP004_AA_108-581 -PAEA---QGQGCMDIARQLI--EQPTGQSINVIMGGGRQMLVSDVTGSAA------DPL DmelP001_AA_75-545 -PAES----VGFHVDIARQLV--ENAPGNRFNVILGGG---MSPMGILNASEVKTTIFEG DmelP012_AA_41-469 --------------EIARQLV--EEEPGRNLNVILGGGLGKFA----------------- DmelP008_AA_64-537 LTYGEGQNDPATCTDIATQLI--TQAPGKNFDVMLGGGIGKFLPNTITDPF------NKK DmelP006_AA_56-531 TSYGV---DANSCIDMATQLV--TQTPGKNFEVMFGGGMGKFLPNSIVDSH------GNP DmelP007_AA_57-529 TSYGV---DASTCVDMATQLV--TQTPGKNFEVMFGGGMGKFLPKTTKDSH------GKY DmelP003_AA_60-520 ATDCG---AGSGINDIAYQLA--RGEVGSKLKVIMGGGRKHFVDSSLESW---------- DmelP009_AA_48-510 EEACG--ELSDGLQDIAVQLI--HGEVGSKLKVMLGGGKRSFYS-----PE------HYD DmelP011_AA_37-522 TKLGQ---NPGNCPDIAQQLI--DGDVGKRLRVVMGGGTIKFLPNTTNDVF--------- DmelP013_AA_62-534 VGDNG---DPDLCPDAAAQLI--NSPVGQKLNVIMGGGRENFLPKGVTDSS------GAP DmelP002_AA_46-516 ISSKC---SPDVNTDIARQLV--EWPVGQELRVIMGGGRSYFRDQSQHDET------GVS DmelP005_AA_41-514 ANREC---DPEQTIDIARQLV--EQPVGQQLKVILGGGRKNFIDATVNDEE-----GYP- NvecP001_AA_32-504 VSRGY---GNTSCKDMAQQLVDFQGSVGDGIEVVMGGGRRSFLPNTTRDPE------HVN HsapP002_AA_20-492 -PPEA---LSQGCKDIAYQLM----HNIRDIDVIMGGGRKYMYPKNKTDVE------YES HsapP002_AA_20-492 -PPEA---LSQGCKDIAYQLM----HNIRDIDVIMGGGRKYMYPKNKTDVE------YES HsapP001_AA_22-493 -PASA---RQEGCQDIATQLI-----SNMDIDVILGGGRKYMFPMGTPDPE------YPA HsapP001_AA_22-493 -PASA---RQEGCQDIATQLI-----SNMDIDVILGGGRKYMFPMGTPDPE------YPA HsapP003_AA_39-511 -PASA---RQEGCQDIATQLI-----SNMDIDVILGGGRKYMFRMGTPDPE------YPD HsapP003_AA_39-511 -PASA---RQEGCQDIATQLI-----SNMDIDVILGGGRKYMFRMGTPDPE------YPD HsapP004_AA_21-493 -PASA---RQEGCQDIATQLI-----SNMDIDVILGGGRKYMFPMGTPDPE------YPD HsapP004_AA_21-493 -PASA---RQEGCQDIATQLI-----SNMDIDVILGGGRKYMFPMGTPDPE------YPD SpurP004_AA_38-454 -PR-----KQEECNDLAYQLI----MENDFINVILGGGRQEFLPTRVEDPE------YYD SpurP003_AA_27-502 -PRGE---RNLGCVDMAQQFV-----SNNNIQVALGGGRMKFMSRINRDPE------YPS SpurP002_AA_22-490 IEDGE---DGKGCKDIALQLI----EDNPFIKVILGGGRRMFYNNTELDPE------DPS SpurP001_AA_29-499 -DDRD---KREGCKDIALQLI----EHGKNMNVIMGGGRRELTPRNVEDPE------YDG : . : :*** : ScerP022_AA_39-535 -YGHHGARKDGRDLIDEA------QSNGWQ---YVGD----RKNFDSLLKSHGENVTLPF DdisP001_AA_81-550 ---------------------VSSKYNYS----YVES----KQEMEQV-------EAGRI DmelP010_AA_65-475 VDEMLCESNDGRNLLKDW---RNQKLKESKINRIIFDLIQRRDELESL---NSS-SFDYL DmelP004_AA_108-581 DTWA-GQSKDGRDLIRDW---RLKKADEGVSHAVVQN----NRELWNL---NGQ-DVDYV DmelP001_AA_75-545 PTETICTRGDNRNLPAEW---LAHHANDTVPPALVHN----RKDLLNV---NVK-KVDHL DmelP012_AA_41-469 -----DERRDGKDLLAQW---RESNPNGC----FSRS----LKELRNC---T-D-ATGTL DmelP008_AA_64-537 -----GERSDGVNLLSRW---QGLHPGGV----LAYN----RNQLLSV---NVS-KITNL DmelP006_AA_56-531 -----GERSDGVNLLSRW---QGLHDGGV----LVTN----RNQLLKL---NVS-AVSSV DmelP007_AA_57-529 -----GERSDGVNLLSRW---QGLHDKGV----LVTN----RKQLLNL---DVS-AASSI DmelP003_AA_60-520 -----GKRTDGLNLIDEF---KSASENNV----YVTT----AAELAAV---DVT-KTDRL DmelP009_AA_48-510 K----GRRTDGRNLVEEF---EALDAGNT----FVKT----QKKLLNV---NAT-ETGRL DmelP011_AA_37-522 --GNKGQRLDNRNLIEEW---QQTKPGNAR---VVFS----RTDLLNN---DAQ-NTDFL DmelP013_AA_62-534 -----GRRLDGRNLIDEW---KNQHTNSAQ---YVEN----RRELLNL---SNH--TSRV DmelP002_AA_46-516 -----GLRTDGRDLISDW-REIKKQQGAEGK--YVWS----LKGLKET---DIS-KTDYL DmelP005_AA_41-514 -----GKRTDGRHLIRSW---LDQKKEANVSAKYVWS----RKGLSLV---DLE-NTDYL NvecP001_AA_32-504 KT---GERYDGRNLIQEW---LNKREGSV----YAWN----KTQFDAV---DPK-TTKHF HsapP002_AA_20-492 DEKARGTRLDGLDLVDTWKSFKPRYKHSH----FIWN----RTELLTL---DPH-NVDYL HsapP002_AA_20-492 DEKARGTRLDGLDLVDTWKSFKPRYKHSH----FIWN----RTELLTL---DPH-NVDYL HsapP001_AA_22-493 DASQNGIRLDGKNLVQEW---LAKHQGAW----YVWN----RTELMQA---SLDQSVTHL HsapP001_AA_22-493 DASQNGIRLDGKNLVQEW---LAKHQGAW----YVWN----RTELMQA---SLDQSVTHL HsapP003_AA_39-511 DYSQGGTRLDGKNLVQEW---LAKRQGAR----YVWN----RTELMQA---SLDPSVTHL HsapP003_AA_39-511 DYSQGGTRLDGKNLVQEW---LAKRQGAR----YVWN----RTELMQA---SLDPSVTHL HsapP004_AA_21-493 DYSQGGTRLDGKNLVQEW---LAKHQGAR----YVWN----RTELLQA---SLDPSVTHL HsapP004_AA_21-493 DYSQGGTRLDGKNLVQEW---LAKHQGAR----YVWN----RTELLQA---SLDPSVTHL SpurP004_AA_38-454 VT---GRREDGNNLIGQW---QGEKEASSSH--YVWN----KEDFDNV---EPT-TTDYL SpurP003_AA_27-502 MP---GSRIDGRNLIQEWINNKPDQDRAH----YVWN----EADFNKI---DPE-QTDYL SpurP002_AA_22-490 DR---GNRTDGRNLIEEW---QNGKTNAR----YVWN----KEQFDAI---DED-TTDYL SpurP001_AA_29-499 DY---GQRLDGRNLIEDW---LEDKDPMRSH--YVWN----LQDFNRV---NAE-TTDHL : . ScerP022_AA_39-535 LGLFADNDIPFEIDR----DEKE---YPSLKEQVKVALGALEK-ASNEDKDSNGFFLMVE DdisP001_AA_81-550 LGLFADYNIPWEIDRLR--DPTLLSTKPSLQEMTTKALNLISQNNE----N--GFFLMVE DmelP010_AA_65-475 MGVMANGDLS---------GNSK---APSLKLMVDKSLNVLTKYKQ-------GYLLIVE DmelP004_AA_108-581 LGIFANGHLMYDHERDR--SDAG---MPSLSNMTLKALEVLGN-SD----K--GFLLVVE DmelP001_AA_75-545 MGLFRNNHITYSIAR-----EAG---EPSLQEMTETALGILER-GD----ESNGFVLLVE DmelP012_AA_41-469 LGIFSDSHMSYHLAA----SKEL----PRLCDMAAAAIEKLER-KSQEDGN--GYFVFIE DmelP008_AA_64-537 IGTFRSGVMSFNKMA----DPKE---EPTLAEMTRKAIEVVSKRDG-------GYFLFVE DmelP006_AA_56-531 IGLFQSKLMNFHLEA----DDTY---QPTLSELTEVTIKKLSQ-NKE---H--GYFAFIE DmelP007_AA_57-529 IGTFQSGLMDFHMDA----DPTY---QPTLSELTEVAIKKLSH-NE----N--GYFVFIE DmelP003_AA_60-520 LGLFNDDHLQYLMETT---TESS---QPTLEQMTRKAIEYMSQ-NE----Q--GYFLFIE DmelP009_AA_48-510 LGLFSKSHMHYHLEQLAD-PDNN---EPTLEEMTQKAIEVLET-EE----Q--GYFLFVE DmelP011_AA_37-522 LGLFNASHLAYHMD-----DSID---TPTLPEMTAAAINVLSR-DP----N--GYFLFVE DmelP013_AA_62-534 LGLFAPYHMAYHLDA----SPAE---QPTLEEMVQSAMEILER-QSA--GR--GYFLFVE DmelP002_AA_46-516 LGLFDTSHLPYHGDRRRTHYEDA---EPSLSDMTEAAIKMLSK-NE----E--GYFLFVE DmelP005_AA_41-514 LGLFANDHLPYNGDRDRKRSQLA---DPSLSELTEAAITVLSR-ND----K--GFFLFVE NvecP001_AA_32-504 LGMFESSHMQFAIDRDE--DVGG---EPSIAEMVEKAVSILKN-ND----NGKGFFLAVE HsapP002_AA_20-492 LGLFEPGDMQYELNR----NNVT---DPSLSEMVVVAIQILRK-NP----K--GFFLLVE HsapP002_AA_20-492 LGLFEPGDMQYELNR----NNVT---DPSLSEMVVVAIQILRK-NP----K--GFFLLVE HsapP001_AA_22-493 MGLFEPGDTKYEIHR----DPTL---DPSLMEMTEAALRLLSR-NP----R--GFYLFVE HsapP001_AA_22-493 MGLFEPGDTKYEIHR----DPTL---DPSLMEMTEAALRLLSR-NP----R--GFYLFVE HsapP003_AA_39-511 MGLFEPGDMKYEIHR----DSTL---DPSLMEMTEAALRLLSR-NP----R--GFFLFVE HsapP003_AA_39-511 MGLFEPGDMKYEIHR----DSTL---DPSLMEMTEAALRLLSR-NP----R--GFFLFVE HsapP004_AA_21-493 MGLFEPGDMKYEIHR----DSTL---DPSLMEMTEAALLLLSR-NP----R--GFFLFVE HsapP004_AA_21-493 MGLFEPGDMKYEIHR----DSTL---DPSLMEMTEAALLLLSR-NP----R--GFFLFVE SpurP004_AA_38-454 LGLFEPGRMQYGADRAA--DGAG---EPSLAEMTEKAIKVLGR-DE----D--GFFLVVE SpurP003_AA_27-502 LGLFEYSLMKFDIRRDN--DTGG---EPSIAEMTDKAIRILSK-NP----N--GFFLFVE SpurP002_AA_22-490 FGLFEDSHMRYASES----EEGN---DPSLASMTEKAIKMLQK-EE----K--GFFLAVE SpurP001_AA_29-499 IGLFQPSHMKYETDRRW--DRAG---EPSLAQMTEKAIKILQRTSD----N--GFFLFVE :* : * : . :: : *: :* ScerP022_AA_39-535 GSRIDHAGHQNDPASQVREVLAFDEAFQYVLEFAENSD--TETVLVSTSDHETGGL-VTS DdisP001_AA_81-550 GSKIDVAAHINDAPTQIWETDAFDQTFNLVREWAEK-D--GNTIVIVTADHETGGLTLAN DmelP010_AA_65-475 -QFIPSGIDKREQLQLLNDTL---------VNLHKD----QDTLTLV------------- DmelP004_AA_108-581 AGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADH-------SH DmelP001_AA_75-545 GGRIDQGHHMNYARAALHELYEFDLAIQAAVNNTDP----DETLILVTADH-------SH DmelP012_AA_41-469 GGRIDHGHHETRVGYALDEMVEFDAAVETVIQMTDP----RDTLVVVTADH-------SH DmelP008_AA_64-537 GGLIDYGNHFNSPTYSLSETLQFEQAVQEALDITDP----EETLIVVTSDH-------AH DmelP006_AA_56-531 GGLIDYGNHYTKAGYALDEALEFEKAIQLARDMTDI----EDTLIVVTADH-------GH DmelP007_AA_57-529 GGLIDYGNHYTQAGYALDEALEFEKAIQLAREMTNI----SDTLIVVTADH-------GH DmelP003_AA_60-520 GGRIDQAHHINQARMALNETIEFSKAIAAAQELTSE----DDTLLVVTADH-------SH DmelP009_AA_48-510 GGKIDISHHETMARIALDETAELSKAVKKAREMTNP----EETLIVVTSDH-------SH DmelP011_AA_37-522 GGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNP----WDTLIVVSADH-------GH DmelP013_AA_62-534 GGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTST----DDTLIVVSSDH-------SH DmelP002_AA_46-516 SGRIDMAHHATKAMKALEDTEEFAAAVELARKMTDE----EDTLIVVTSDH-------SH DmelP005_AA_41-514 GARIDMAHHDTFAKRSLEDTAEFARAVQKARELTSE----DDTLIVVTADH-------AH NvecP001_AA_32-504 AGLIDIGHHNGIARQALNEVVNLEEGVAKAVEMTDK----EDTLIISTADH-------GH HsapP002_AA_20-492 GGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSS----EDTLTVVTADH-------SH HsapP002_AA_20-492 GGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSS----EDTLTVVTADH-------SH HsapP001_AA_22-493 GGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSE----EDTLTLVTADH-------SH HsapP001_AA_22-493 GGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSE----EDTLTLVTADH-------SH HsapP003_AA_39-511 GGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSE----EDTLSLVTADH-------SH HsapP003_AA_39-511 GGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSE----EDTLSLVTADH-------SH HsapP004_AA_21-493 GGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSE----EDTLSLVTADH-------SH HsapP004_AA_21-493 GGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSE----EDTLSLVTADH-------SH SpurP004_AA_38-454 --------------------MLSNFVCHVTIGIVDD----QES----------------- SpurP003_AA_27-502 GGRIDHGHHFGVANLALTETVAMDKAIDVALGLVDT----EETLVMVTSDH-------AH SpurP002_AA_22-490 GGRIDHAHHAGNAYNALGDAIAMSDAVAMALEMTSD----SDTLIVVTADH-------AH SpurP001_AA_29-499 AGRIDHGHHDGMALDALTETLALDEAIGVALRLTSA----EDTLIVSTADH-------AH . :: ScerP022_AA_39-535 RQVTASYPQYVWYPQVLANA-----THSGEFLKRKLVDFVHEHKGASSKIENFIKHEILE DdisP001_AA_81-550 QMVIDGNPKYSWSPETLLTV-----NKSADLMAELI-------KGGADPT------KLIF DmelP010_AA_65-475 LMTNAIYPKPSLDV-----------SEETETISLLP---------------------EIF DmelP004_AA_108-581 SLTINGHPDRGSSILGLAG------NSKTEGTPYTT---------------------LTY DmelP001_AA_75-545 AVTFNGYALRGADILGTANS-----HEKNDPMFYET---------------------ISY DmelP012_AA_41-469 TLSMSGYAKRGTPILGMDAQ-----QRDVNGVPYST---------------------LNY DmelP008_AA_64-537 PLTISGYPGRGTPILGLNQD-----DTDVNGVKYAT---------------------LNY DmelP006_AA_56-531 AVSIAGYPGRGTPILGINQH-----DTDINGVQYSV---------------------LNY DmelP007_AA_57-529 AVSIAGYPGRGTPILGLNQH-----DTDINGVKYSV---------------------LNY DmelP003_AA_60-520 VFTYAGYSYRGSDVFGKTP------VNGHDGKPYMV---------------------LSY DmelP009_AA_48-510 TFSVSGYQPRGSDIFGAAK------ANGKDGKPYLA---------------------LSY DmelP011_AA_37-522 TVTISGYPDVNNSIVGLNSE-----LSNVDQLPYTS---------------------ISY DmelP013_AA_62-534 TMSLAGYSSRKNDIFGINDG-----QLAADDLPYAT---------------------LSY DmelP002_AA_46-516 TMSINGYPYRRQNILSLAP------NLADDELPFTI---------------------LSY DmelP005_AA_41-514 VMSINGYPYRDQEITGLA-------QLADDNLPYTI---------------------LSY NvecP001_AA_32-504 VFTLTGYPDINSPIFGLMKQDGEVKLALNDNKPYTI---------------------LGY HsapP002_AA_20-492 VFTFGGYTPRGNSIFGLAPM-----LSDTDKKPFTA---------------------ILY HsapP002_AA_20-492 VFTFGGYTPRGNSIFGLAPM-----LSDTDKKPFTA---------------------ILY HsapP001_AA_22-493 VFSFGGYTLRGSSIFGLAP------SKAQDSKAYTS---------------------ILY HsapP001_AA_22-493 VFSFGGYTLRGSSIFGLAP------SKAQDSKAYTS---------------------ILY HsapP003_AA_39-511 VFSFGGYPLRGSSIFGLAP------GKARDRKAYTV---------------------LLY HsapP003_AA_39-511 VFSFGGYPLRGSSIFGLAP------GKARDRKAYTV---------------------LLY HsapP004_AA_21-493 VFSFGGYPLRGSSIFGLAP------GKARDRKAYTV---------------------LLY HsapP004_AA_21-493 VFSFGGYPLRGSSIFGLAP------GKARDRKAYTV---------------------LLY SpurP004_AA_38-454 ----------------------------ADRLPYTT---------------------LTY SpurP003_AA_27-502 TFKMAGYSARGNPILGKSD------GRSTDLGSYTT---------------------VGY SpurP002_AA_22-490 TMSIGGYPDRGNKILGLAG------YFGSDDLPFTT---------------------LGY SpurP001_AA_29-499 VMTMAGYASRGNPILGLEDH-----YLADDDLPYAT---------------------LSY : ScerP022_AA_39-535 KDL-GIYDYTDSDLETLIHLDDN-------ANAIQDKLNDMVSFR--------AQIGWT- DdisP001_AA_81-550 DN--TGYTLTS---------DDL-------KEINRTKSAYYLNQVIGRIVSNYADIGFT- DmelP010_AA_65-475 ------------------------------NEAES-EIQKRLHQ-----------MPSE- DmelP004_AA_108-581 GTSYQGFQVDPQT----QSRKDP-------TADDI-TAWEYTQQA--------A-INTD- DmelP001_AA_75-545 ANG-PGYWDHLANDSRPQNSSNMWMPLKHFTAEER-AAPTYRHLA--------T-VPRK- DmelP012_AA_41-469 AIG-KWQSLDKD-----GRRE---------SPSKTLSPTSYTPSY----------IHGR- DmelP008_AA_64-537 AVGTNQYLDEH------GQRIDL---------TDQIGAEDFIHPS--------Y-IHGT- DmelP006_AA_56-531 AAG-PNQYLDEN-----GQRIPL-------DDIL--GSDDAITPS--------Y-IPKD- DmelP007_AA_57-529 AAG-PNQYLDEH-----GQRIPL-------DDIL--GPDDAISPS--------Y-IDKE- DmelP003_AA_60-520 ANG-PSYENFYDAET--MERKDP-------TTVVK-GDHDDEFPS--------G-VPID- DmelP009_AA_48-510 ANG-KSFQDYYNTET--HERVDP-------TSLPTIGDFDQLFPA--------M-VPLE- DmelP011_AA_37-522 ANG-PAYERFYKSTDGVVERVDL-------RNLDF-SKPDAIYPH--------G-VPMT- DmelP013_AA_62-534 ANG-PGYDSNYLREGGAVRRKNL-------RAINM-KNKDFMFPS--------T-VPLE- DmelP002_AA_46-516 ANG-PGFDDTYSTK---DGRIDL-------SHADT-TSAEFEFQA--------T-VPLS- DmelP005_AA_41-514 ANG-PGYYSGYNRA---EGRALL-------KEKLV-ADSDYQYPT--------L-APLD- NvecP001_AA_32-504 MNG-PGAVK--------GVRANL-------TGVDT-GAKDFKQQA--------LYIGYDY HsapP002_AA_20-492 GNG-PGYKVVG------GERENV-------SMVDY-AHNNYQAQS--------A-VPLR- HsapP002_AA_20-492 GNG-PGYKVVG------GERENV-------SMVDY-AHNNYQAQS--------A-VPLR- HsapP001_AA_22-493 GNG-PGYVFNS------GVRPDV-------NESES-GSPDYQQQA--------A-VPLS- HsapP001_AA_22-493 GNG-PGYVFNS------GVRPDV-------NESES-GSPDYQQQA--------A-VPLS- HsapP003_AA_39-511 GNG-PGYVLKD------GARPDV-------TESES-GSPEYRQQS--------A-VPLD- HsapP003_AA_39-511 GNG-PGYVLKD------GARPDV-------TESES-GSPEYRQQS--------A-VPLD- HsapP004_AA_21-493 GNG-PGYVLKD------GARPDV-------TESES-GSPEYRQQS--------A-VPLD- HsapP004_AA_21-493 GNG-PGYVLKD------GARPDV-------TESES-GSPEYRQQS--------A-VPLD- SpurP004_AA_38-454 LNG-PGGVNVQTNWANNGNRRDY-------SGVDT-ESRTWQQDA--------I-IPLE- SpurP003_AA_27-502 MNG-PGAIISSLSYRLLGRRPPV-------TDANT-GRPFYLPQA--------V-VPTF- SpurP002_AA_22-490 LNG-PGAEEVRQSYSDTGMRPNL-------TEIDT-EDKDYLQQA--------I-VPLS- SpurP001_AA_29-499 ANG-PGARHMASSFQKHGARENL-------TSVDT-EETGHRQQA--------L-VPFD- ScerP022_AA_39-535 THGHSAVDVNIYAYANK---KA----TWSY---------------VLNNLQGNHENTEVG DdisP001_AA_81-550 TGGHTGEDVNLYT-------FGDTISEGKFETRLKDHQTEIVDNYIDPILRGNINNIDIA DmelP010_AA_65-475 --------SLLFA-------QG----PKSS------------------IFQGVRKETFLA DmelP004_AA_108-581 ENLHGGSDVTIHA-------DG----AMSY------------------LFHGVHEQSYVA DmelP001_AA_75-545 DETHGGEDVAVFA-------YG----PGSS------------------LIRGVFEQNYLA DmelP012_AA_41-469 KGVHSGEDVVVFA-------MG----PQSH------------------LFGGVMEQNLLP DmelP008_AA_64-537 IGVHAGDDVGIFA-------TG----PQSH------------------LFTGVMQQSTIP DmelP006_AA_56-531 QGVHSGEDVGIFA-------SG----PQSH------------------LFTGVMQQSTIP DmelP007_AA_57-529 IGVHSGEDVGIWA-------SG----PQSH------------------LFTGVMQQSTIP DmelP003_AA_60-520 MDSHGGDDVPVYA-------LG----PWAH------------------LFTGVYEQSTIP DmelP009_AA_48-510 SETHGGEDVGVFA-------SG----PWAH------------------LFTGVYEQNTIP DmelP011_AA_37-522 EETHGGGDVAVYAHVVEYLLQG----PWSH------------------LFTGVYEQSTLP DmelP013_AA_62-534 SETHGGDDVAVFA-------SG----PYAQ------------------LFTGVFEQHFIP DmelP002_AA_46-516 SETHGAEDVGVFA-------SG----PFEH------------------LFTGNYEQSAIP DmelP005_AA_41-514 AETHGGDDVAVYA-------SG----PYAQ------------------YFSGNYEQSNIP NvecP001_AA_32-504 DEAHGSQDVGIYS-------RG----PWAH------------------LLTGVVEQNVIF HsapP002_AA_20-492 HETHGGEDVAVFS-------KG----PMAH------------------LLHGVHEQNYVP HsapP002_AA_20-492 HETHGGEDVAVFS-------KG----PMAH------------------LLHGVHEQNYVP HsapP001_AA_22-493 SETHGGEDVAVFA-------RG----PQAH------------------LVHGVQEQSFVA HsapP001_AA_22-493 SETHGGEDVAVFA-------RG----PQAH------------------LVHGVQEQSFVA HsapP003_AA_39-511 EETHAGEDVAVFA-------RG----PQAH------------------LVHGVQEQTFIA HsapP003_AA_39-511 EETHAGEDVAVFA-------RG----PQAH------------------LVHGVQEQTFIA HsapP004_AA_21-493 GETHAGEDVAVFA-------RG----PQAH------------------LVHGVQEQTFIA HsapP004_AA_21-493 GETHAGEDVAVFA-------RG----PQAH------------------LVHGVQEQTFIA SpurP004_AA_38-454 AETHGGADVPVYA-------QG----PWSH------------------MFAGVHEQNYIA SpurP003_AA_27-502 LETHGGDDVAIFA-------IG----PMSH------------------LVHGVHEQNYVS SpurP002_AA_22-490 SESHGGDDVAIYA-------TG----PMAH------------------LFHGVQEQSYIA SpurP001_AA_29-499 EETHGGQDVMVYA-------RG----PMAH------------------LFHGVQEQSYIP : : . . * :: : ScerP022_AA_39-535 QFLENFLELNLNE-VTDL DdisP001_AA_81-550 SFIIKTLNLDIQS-ITE- DmelP010_AA_65-475 HAISHVLSRS-------- DmelP004_AA_108-581 HAISYALRIGRF------ DmelP001_AA_75-545 YVMSYAGCLGPAKD---- DmelP012_AA_41-469 HIMGYAACLGNG------ DmelP008_AA_64-537 HLMAYASCIGNGPT---- DmelP006_AA_56-531 HLMAYAACIGSGKQVC-- DmelP007_AA_57-529 HLMAYASCVGSGKQ---- DmelP003_AA_60-520 HMMAYASCLGDGHTM--- DmelP009_AA_48-510 HMMAFAACVG-------- DmelP011_AA_37-522 HLMGFASCLGPGITYCDL DmelP013_AA_62-534 HALGYASCLSDRN----- DmelP002_AA_46-516 AMMAYAANIGPF------ DmelP005_AA_41-514 ALMARAAGIGPY------ NvecP001_AA_32-504 HVMDHALCLS-------- HsapP002_AA_20-492 HVMAYAACIGA------- HsapP002_AA_20-492 HVMAYAACIGA------- HsapP001_AA_22-493 HVMAFAACLEPYT-AC-- HsapP001_AA_22-493 HVMAFAACLEPYT-AC-- HsapP003_AA_39-511 HVMAFAACLEPYT-AC-- HsapP003_AA_39-511 HVMAFAACLEPYT-AC-- HsapP004_AA_21-493 HVMAFAACLEPYT-AC-- HsapP004_AA_21-493 HVMAFAACLEPYT-AC-- SpurP004_AA_38-454 HAVRHAACLD-------- SpurP003_AA_27-502 HVMQRAACIGYYADNC-- SpurP002_AA_22-490 HVMRNAGCYDETD----- SpurP001_AA_29-499 HVIRYAACLA-------- :