MUSCLE (3.8) multiple sequence alignment PTP-ER_DmelP044_AA_887-1369 QKRIFRDLHK----------EFWDLPLNH--QEKPMVFGSQTKNRYKTILPNENSRVLLE PTPN5_RR_NvecP077_AA_41-319 KLITFEELGECVDNTKQLYAEFWEIPMNH-PPAEERLPGSSYRNRYPSILPNSRTRVSL- PTPN5_RR_SpurP062_AA_0-198 ------------------------------------------------------------ PTPN7_HsapP083_AA_186-457 --LTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLG PTPRR_HsapP084_AA_375-647 RILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLR PTPN5_HsapP082_AA_282-555 RVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLT PTP-ER_DmelP044_AA_887-1369 SESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLM PTPN5_RR_NvecP077_AA_41-319 PQIPD----------------DPLSSYINANVLKGYGEEINAFIATQGPLSCTVNDFWRM PTPN5_RR_SpurP062_AA_0-198 ----------------------------------GYDREPTAFVATQGPMAHTLADFWRM PTPN7_HsapP083_AA_186-457 RAQSQ-----------------EDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEM PTPRR_HsapP084_AA_375-647 PKNVT----------------DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQM PTPN5_HsapP082_AA_282-555 SPDPD----------------DPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRM * . . ::*****: *: :** * PTP-ER_DmelP044_AA_887-1369 IYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIE--- PTPN5_RR_NvecP077_AA_41-319 IW---------------------------YHHCPIIVMITKLKERNETKCERYWPDPTFR PTPN5_RR_SpurP062_AA_0-198 IW---------------------------FTNAPVIVMVTKIKERKRSKCEMYWPQG--- PTPN7_HsapP083_AA_186-457 VW---------------------------QEEVSLIVMLTQLREGKE-KCVHYWPTE--- PTPRR_HsapP084_AA_375-647 VW---------------------------QEDSPVIVMITKLKEKNE-KCVLYWPEK--- PTPN5_HsapP082_AA_282-555 VW---------------------------QEHTPIIVMITNIEEMNE-KCTEYWPEE--- :: ***:*:: * : ** *:* PTP-ER_DmelP044_AA_887-1369 LNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKV PTPN5_RR_NvecP077_AA_41-319 MQEKYG--------------------------------------------------DIVV PTPN5_RR_SpurP062_AA_0-198 -QGFYG--------------------------------------------------DIDV PTPN7_HsapP083_AA_186-457 -EETYG--------------------------------------------------PFQI PTPRR_HsapP084_AA_375-647 -RGIYG--------------------------------------------------KVEV PTPN5_HsapP082_AA_282-555 -QVAYD--------------------------------------------------GVEI : . : PTP-ER_DmelP044_AA_887-1369 TLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYW PTPN5_RR_NvecP077_AA_41-319 TFD-------------------SALGRDGYQITSLYISH--------SQSPRRLY--HYW PTPN5_RR_SpurP062_AA_0-198 TVE-------------------ETVPKDDYILKIFTLKY--------LNECRQVL--HYW PTPN7_HsapP083_AA_186-457 RIQ-------------------DMKECPEYTVRQLTIQY--------QEERRSVK--HIL PTPRR_HsapP084_AA_375-647 LVI-------------------SVNECDNYTIRNLVLKQ--------GSHTQHVK--HYW PTPN5_HsapP082_AA_282-555 TVQ-------------------KVIHTEDYRLRLISLKS--------GTEERGLK--HYW . * : : : . : * PTP-ER_DmelP044_AA_887-1369 YPDWPDHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIF PTPN5_RR_NvecP077_AA_41-319 YTAWPDHGVPDSPRQLLQLVDEV-------------HLAQDRDDGKTG------------ PTPN5_RR_SpurP062_AA_0-198 YTAWPDNKPPENPVTLLEMIREV-------------EFSRIDPTLPRG------------ PTPN7_HsapP083_AA_186-457 FSAWPDHQTPESAGPLLRLVAEV-------------EESPETAAHP-G------------ PTPRR_HsapP084_AA_375-647 YTSWPDHKTPDSAQPLLQLMLDV-------------EEDRLASQGR-G------------ PTPN5_HsapP082_AA_282-555 FTSWPDQKTPDRAPPLLHLVREV-------------EEAAQQEGPHCA------------ :. ***: * ** * . PTP-ER_DmelP044_AA_887-1369 NAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTD PTPN5_RR_NvecP077_AA_41-319 ----PV-VVHCSAGIGRTGCFVATSIGIKQIQK--------------------------- PTPN5_RR_SpurP062_AA_0-198 ----PV-IVHCSAGLGRTGCYIAITLGMRQMDE--------------------------- PTPN7_HsapP083_AA_186-457 ----PI-VVHCSAGIGRTGCFIATRIGCQQLKA--------------------------- PTPRR_HsapP084_AA_375-647 ----PV-VVHCSAGIGRTGCFIATSIGCQQLKE--------------------------- PTPN5_HsapP082_AA_282-555 ----PI-IVHCSAGIGRTGCFIATSICCQQLRQ--------------------------- *: ::*****:*****: * .*: PTP-ER_DmelP044_AA_887-1369 SDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQ PTPN5_RR_NvecP077_AA_41-319 --------------------------------------ENKVDILKIVCGMRMERGGMVE PTPN5_RR_SpurP062_AA_0-198 --------------------------------------ESMVDILGIVCQIRQDRGGMIQ PTPN7_HsapP083_AA_186-457 --------------------------------------RGEVDILGIVCQLRLDRGGMIQ PTPRR_HsapP084_AA_375-647 --------------------------------------EGVVDALSIVCQLRMDRGGMVQ PTPN5_HsapP082_AA_282-555 --------------------------------------EGVVDILKTTCQLRQDRGGMIQ ** * .* :* :****:: PTP-ER_DmelP044_AA_887-1369 NSEQYELIHRAICLYLK PTPN5_RR_NvecP077_AA_41-319 TDSQYEFVYRALYHHWR PTPN5_RR_SpurP062_AA_0-198 TNEQYEFIHQALCLYEK PTPN7_HsapP083_AA_186-457 TAEQYQFLHHTLALYAG PTPRR_HsapP084_AA_375-647 TSEQYEFVHHALCLY-- PTPN5_HsapP082_AA_282-555 TCEQYQFVHHVMSLY-- . .**::::..: :