MUSCLE (3.8) multiple sequence alignment


PTPRU_HsapP104_AA      MARAQALVLALTFQLC---------APETETPAAGCTFEEASDPAVPCEYSQAQY-DDFQ
PTPRK_HsapP101_AA      MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFD---DGPGACDYHQDLY-DDFE
PTPRM_HsapP102_AA      -MRGLGTCLATLAGLLL--------TAAGETFSGGCLFD---EPYSTCGYSQSEG-DDFN
PTPRT_HsapP103_AA      MASLAALALSLLLRLQL----PPLPGARAQSAAGGCSFD---EHYSNCGYSVALGTNGFT
                            .  *.    *           .  :  :.** *:   :    * *      :.* 

PTPRU_HsapP104_AA      WEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRD
PTPRK_HsapP101_AA      WVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQK
PTPRM_HsapP102_AA      WEQVNTLTKPTSDPWMPSGSFMLVNASGRPEGQRAHLLLPQLKENDTHCIDFHYFVSSKS
PTPRT_HsapP103_AA      WEQINTWEKPMLDQAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRD
                       * ::           :* **:::*::* .  *:.*.: :  :.******::* * . *..

PTPRU_HsapP104_AA      GHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDR
PTPRK_HsapP101_AA      GLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGR
PTPRM_HsapP102_AA      NSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAELAISTFWPNFYQVIFE-VITSGH
PTPRT_HsapP103_AA      RSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGH
                          ** *.: *.** ** ...:**::*     * .****:*****: ***:**     ..

PTPRU_HsapP104_AA      RGYMGLDDILLLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGA
PTPRK_HsapP101_AA      SGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGE
PTPRM_HsapP102_AA      QGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVR
PTPRT_HsapP103_AA      PGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGR
                        **:.:*:: :*.:** .:*** *: :****.** *:*** * *.    :.: **  .  

PTPRU_HsapP104_AA      LVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIA
PTPRK_HsapP101_AA      DIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIA
PTPRM_HsapP102_AA      DAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIA
PTPRT_HsapP103_AA      DTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIA
                         .    .  . *** *:. :  .:. . . ***: .:  * *:**:*:*:*.*** ***

PTPRU_HsapP104_AA      PPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPD
PTPRK_HsapP101_AA      PPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPD
PTPRM_HsapP102_AA      PPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPD
PTPRT_HsapP103_AA      PPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPD
                       **:*  .*.*** *: *:*** *****: .*:**  : *.* : : *.  .**: *****

PTPRU_HsapP104_AA      TEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFAEIQARQLTLQWEPLGYN
PTPRK_HsapP101_AA      TEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYN
PTPRM_HsapP102_AA      TEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYN
PTPRT_HsapP103_AA      VEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYA
                       .**** *******:**** ***.* :*****:*:. *. : ..::.:*.::: **.:** 

PTPRU_HsapP104_AA      VTRCHTYTVSLCYHYTLGSSHNQTIRECV-KTEQGVSRYTIKNLLPYRNVHVRLVLTNPE
PTPRK_HsapP101_AA      ITRCHTFNVTICYHYFRG--HNESKADCL-DMDPKAPQHVVNHLPPYTNVSLKMILTNPE
PTPRM_HsapP102_AA      VTRCHSYNLTVHYCYQVG-GQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPE
PTPRT_HsapP103_AA      VTRCHSYNLTVQYQYVFN--QQQYEAE---EVIQTSSHYTLRGLRPFMTIRLRLLLSNPE
                       :****::.::: * *  .  :::   :   .     ..:.:  * *: .: :.::* ***

PTPRU_HsapP104_AA      GRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIES
PTPRK_HsapP101_AA      GRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRS
PTPRM_HsapP102_AA      GRKESQELIVQTDEDLPGAVPTESIQGSTFEEKIFLQWREPTQTYGVITLYEITYKAVSS
PTPRT_HsapP103_AA      GRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGS
                       ** *.:*  .**:**:*. :. :*:   .:*: *:::*  * :. *:** ***.*.:: *

PTPRU_HsapP104_AA      SDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTGKGFGQAALTEITTNISA
PTPRK_HsapP101_AA      FDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISA
PTPRM_HsapP102_AA      FDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISA
PTPRT_HsapP103_AA      LDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISA
                        **   :..    : :* *.*:.:*  *:***** * :.* * **** ..   .:*:***

PTPRU_HsapP104_AA      PSF-DYADMPSPLGESENTITVLLRPAQGRGAPISVYQVIVEEERARRLRREPGGQDCFP
PTPRK_HsapP101_AA      PTLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAMECYQ
PTPRM_HsapP102_AA      PSMPAY-ELETPLNQTDNTVTVMLKPAHSRGAPVSVYQIVVEEERPRRTKKTTEILKCYP
PTPRT_HsapP103_AA      PSMPEY-DTDTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFS
                       *::  *    :.*.:: .*:**:*.**:..***:*.**::*:* . .. .. .   .*: 

PTPRU_HsapP104_AA      VPLTFEAALARGLVHYFGAELAASSLPEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQA
PTPRK_HsapP101_AA      VPVTYQNAMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQA
PTPRM_HsapP102_AA      VPIHFQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPYKSYRIYFQA
PTPRT_HsapP103_AA      VPVSYRNASSLDSLHYFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQA
                       **: :  *   .  :**.**: . .*  . ***:***.**.*:**.** * *.* *****

PTPRU_HsapP104_AA      ASHLKGETRLNCIRIARKA------------------------ACKESKRPLEVSQRSEE
PTPRK_HsapP101_AA      MSSVEKETKTQCVRIATKAA-----------------------ATEEPEVIPDPAKQTDR
PTPRM_HsapP102_AA      ASRANGETKIDCVQVATKAAIIVTQLTTPYIRIAPAAGDGQLTGAATPKPVPEPEKQTDH
PTPRT_HsapP103_AA      LSKANGETKINCVRLATKAPMGSAQVTPGTPLCLLTTG-----ASTQNSNTVEPEKQVDN
                        *  : **. :*:.:* **                        .    .   :  :. : 

PTPRU_HsapP104_AA      MGLILGICAGGLAVLILLLGAIIVIIRK-------------GRDHYAYSYYPKPVNMTKA
PTPRK_HsapP101_AA      VVKIAGISAGILVFILLLLVVILIVKKRYICWRRHICIRNIRRSYYSYSYYLKLAKKRKD
PTPRM_HsapP102_AA      TVKIAGVIAGILLFVIIFLGVVLVMKKR------------------------KLAKKRKE
PTPRT_HsapP103_AA      TVKMAGVIAGLLMFIIILLGVMLTIKRR--------------RNAYSYSYYLKLAKKQKE
                          : *: ** * .::::* .:: : ..                        * .:  * 

PTPRU_HsapP104_AA      TV-NYRQEKTHMMSAVDRSFTDQSTLQEDERLGLSFMDTHGYSTRG--------------
PTPRK_HsapP101_AA      AMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHNFSPR---------------
PTPRM_HsapP102_AA      TMSSTRQEMTVMVNSMDKSYAEQGTNCDE---AFSFMDTHNLNGRSVSSPSSFTMKTNTL
PTPRT_HsapP103_AA      TQSGAQREMGPVASA-DKPTTKLSASRNDEGFSSSSQDVNGFT-----------------
                       :  . ..*   : .: *.. :. .:   :   . :  * :. .                 

PTPRU_HsapP104_AA      ----------DQRSGGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQM
PTPRK_HsapP101_AA      ----------YENHSATAESSRLLDV-PRYLCEGTESPYQTGQLHPAIRVADLLQHINLM
PTPRM_HsapP102_AA      STSVPNSYYPDETHTMASDTSSLVQSHTYKKREPADVPYQTGQLHPAIRVADLLQHITQM
PTPRT_HsapP103_AA      ----------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQM
                                        ::.:  :   .         .*  .*::**:*********. *

PTPRU_HsapP104_AA      KTAEGYGFKQEYESFFEG----WDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNAD
PTPRK_HsapP101_AA      KTSDSYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSD
PTPRM_HsapP102_AA      KCAEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSD
PTPRT_HsapP103_AA      KRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSD
                       * .:.****:***:: **    ** :*:.::   .*   : :**. ** *  : .*. :*

PTPRU_HsapP104_AA      YINANYI------DGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRV
PTPRK_HsapP101_AA      YINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRV
PTPRM_HsapP102_AA      YINGNYI------DGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRV
PTPRT_HsapP103_AA      YINANYI------DGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRV
                       ***.***      ***:*. *:******  * : *****:*:*: :.*:*:*:*******

PTPRU_HsapP104_AA      KCSRYWPEDSDTYGDIKIMLVKTETLAEYVVRTFALER-----------------RGYSA
PTPRK_HsapP101_AA      KCYKYWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLER-----------------RGYNE
PTPRM_HsapP102_AA      KCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKGGAGGEANCSPSREVSQRGVHE
PTPRT_HsapP103_AA      KCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQK-----------------KGYHE
                       ** .***:*:: * *:*:  :: * *****:***:::.                 .*   

PTPRU_HsapP104_AA      RHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLD
PTPRK_HsapP101_AA      IREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYIVID
PTPRM_HsapP102_AA      IREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVID
PTPRT_HsapP103_AA      IRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAID
                        .*:. ****.**:**** :*****.*:*.**  .**.***:*:*****:*****:*.:*

PTPRU_HsapP104_AA      VMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSEFKA
PTPRK_HsapP101_AA      IMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKA
PTPRM_HsapP102_AA      IMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRS
PTPRT_HsapP103_AA      TMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRS
                        ****** ******:***. * :.*:*::******:*:***********:*::*..:..:

PTPRU_HsapP104_AA      TYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCL
PTPRK_HsapP101_AA      AYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCL
PTPRM_HsapP102_AA      LYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCL
PTPRT_HsapP103_AA      LYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCL
                        * :: .:*.*:***::.:**.*** *** :  *:***. ****.:*** **:** ****

PTPRU_HsapP104_AA      PFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQL
PTPRK_HsapP101_AA      PFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEV
PTPRM_HsapP102_AA      PFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDV
PTPRT_HsapP103_AA      PFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEM
                       ****: **:*.******* **: ..:**:** :** .*. ****** ** *:*:****::

PTPRU_HsapP104_AA      NQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHF
PTPRK_HsapP101_AA      DLSQG---CPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQF
PTPRM_HsapP102_AA      DPAQL---CPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQF
PTPRT_HsapP103_AA      DTAQF---CMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHL
                       : ::    * *****     :* ::** :*   : *:: *:**: * :* *:*: :*.::

PTPRU_HsapP104_AA      QFLRWSAYRDTPDSKKAFLHLLAEVDKWQAE--SGDGRTIVHCLNGGGRSGTFCACATVL
PTPRK_HsapP101_AA      QYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVV
PTPRM_HsapP102_AA      QFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVC
PTPRT_HsapP103_AA      QYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVC
                       *:: *. :*:.* **.::*:::  ::*** :    :***::********** ***   * 

PTPRU_HsapP104_AA      EMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEGLESR
PTPRK_HsapP101_AA      EMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS---
PTPRM_HsapP102_AA      EMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG---
PTPRT_HsapP103_AA      EMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF---
                       **:. :. :***. .***** *.***:  :**.* *:******..