CLUSTAL W (1.81) multiple sequence alignment Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA PEPVLFFEVKEIIDNNVTFVWSGPSSDFEGYGLAIAPPINSFTSSLDEKEITIQVNTNKE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA FLASIYTYAGPWSSEPSTLNVIIDPREPGTIDVEELTSTSISITWTEFAGITDYIVNLTL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA ASNNTELFSGVIRSSLKASFSGLMPGEEYIIKIGLQCAGEVLSLRQYTLPLEPVCAVFTW Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA VTEDSVTLQWSRPESQLFGYEIMYDDGSGPYSPINVFDRNSLQLERTIMGLMDGPGVEVN Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA ITTLAGAGMTQTRSNPVKISPSSLGSAFNITTVTSTSIAFGWYDLPDASEYDVCIQQIMG Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA NATCRNVTEKTTEFSDLFPGAAYTFSLGWESACGVTLTFNTGQVTWDIPESEYDFFEVTY Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA SPDHGFTNSPAPIYRMDINENQTRVEFSFIGILPDTNYNVTVVTVVGALDVRSEPSYISF Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA RTESPANGSVAVTALSADSIQVGWGNNTQDYVNIRFNLDGENQTVCENEFICAVGNGSEF Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ----------------------MSKLPAPQPPGNVAVTEETTSTITLSWSPPSQEQFFGY Spur_Spur_PTPRB5.AA FNINDLQSGRKYHVFIDQDGVCGTLQQYTRPLPPVNIETADSQLTSLLIAWSDPGNETMF Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ----------MDFLIIFLLLFIGTSETQVDVSNVVPGTRYDITISSISTTYTSPVTRIVT Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ILEYEGTGFSTELGRTPATSFLPRHQESVTLKGLTPGISYSIKISSFVEYDDVTTRSNIV Spur_Spur_PTPRB5.AA DRYYVAYERADELGNFTEVGYLYPNVTSIFLEGLTPRTEYLFNVSTVVGEGKAQAFSDGE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA -------------------------------------------------MLYQLSKATTR Dmel_Ptp4E.AA --------------------MDCATRKQQQLRAHHQQQQIQIQTHGRKRQQLQKQRHNHH Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA --------MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQW Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ---------------------------MAGAGGGLGVWGNLVLLGLCSWTGAR------- Hsap_PTPRQ.AA TNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSK Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------MIRWKYELHSLIWLFLVLHLSKCQSDSLTT------ Spur_Spur_PTPRB3.AA TSLGTTMSTSSLNIVAKFVNQTSFTIEWQPAVGASSYVTRVSEVTGVEISSVTNVNGDYE Spur_Spur_PTPRB5.AA LYSAYTAEANGTVTVFEYDTTSIMFTWPNMTSDLNVSISIIPNDGALDLNIGNRSAQVTG Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ---------------------------MVLTADQCSAAYRVSSQDETKTTIERTNLGN-- Dmel_Ptp10D.AA IRLKRQKAVPQHRWLWSLAFLAAFTLKDVRCADLAISIPNNPGLDDGASYRLDYSPPFGY Dmel_Ptp4E.AA HYYQNSQQQQKHFVWLVVGILTIFLAQHANAADLVINVPNASS-NANAFYRIDYSPPFGF Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA MWTEDEKLLHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA PDSLEVLLTNLNPGTTYEIKVAAENSAGIGV----------------------------- Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA RTEHRLVPGRNYQIEVSATGTGQSD----------------------------------- Spur_Spur_PTPRB5.AA LVPGRLYNISVLPFETIFQRTKPLPPYNVSICPDVGETFFSFCVRLTPPTGDYNAFYVLT Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA PEPNTTIASREIGDEIQFSRALPGTKYNFW------------------------------ Dmel_Ptp4E.AA PEPNTTIPASDIGKDIKFSRALPGTEYNFW------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA KQGSRVVVKKARKYLHSWMKIDVNKEGKLVN----------------------------- Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA MDDFQAVQERRKRSPQEFGFDLAKRLGGNELETVLDDLVPDTGYTVQAVTVSGAGSMNEE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA CSAPVETIGRTLMIGETELVFTKVNSTAFRVWWNRDRNFTGNYNITAPPSDQQMLMSHDS Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA IPFADFEGVLSSTVYNVLVETGPSGSVAAGSVRTGYDLETLSPVERMLNGDPVEENPDSV Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA SNVFLTSLDEITLIASWDPPDVVTSSNEILLTLSTNSTEVRSVNVSGNVTEFVFKCLEPE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA TEYTVELVSLLQESGSFEKQYATETPPTATNSTVGLRPANESTPVVDSLTSTSIAVRWGR Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA LGQAGYSVCLVEYCRQRLDDPVCLTNNSDLCSIEGEFDSLDPGQLYIVSYMDPYGVSMEL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA EKVRTRPSPPSSVTITAVSSRLIEIRWTPPPNIAEMVLEYFDTESPSNTWEARIDNDGMY Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA DIHGLDADTSYTVRLSSVGRTGAGDGSDGKRLSGEPLEEVVRTSARILSVVNTANALTFL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA -------------------------------------------------FS--------D Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA WDEQPNPETFTGYLITSASINEVIPKQSEETSYQKSISNLTPGQLYEVSLFLQPITTFPA Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA -------------------------------------------------LYYTNFTHHDW Dmel_Ptp4E.AA -------------------------------------------------LYYTNSTHREQ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA -------------------------------------------------ESLCLQKAGLG Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA -------APAPNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQ------------- Hsap_PTPRQ.AA PFLFQTAESAPGKVVNLTVEAYNASAVKLIWYLPRQPNGKITSFKISV------------ Spur_Spur_PTPRB2.AA ----------------MRRASESCVGKETRSDYPALAEQLGEGGNVEH------------ Hsap_PTPRJ.AA ------MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSP------------ Cele_dep-1.AA -------SAEQHELFAIKKDSLSPWSQILVSLPRRHPLYQSFAAKIQD------------ Spur_Spur_PTPRB3.AA -----TVEQRTLPSAVSNVDVVPEAAALTLSWDPVFGDVDGYYASYQL------------ Spur_Spur_PTPRB5.AA PLDQLQVRTAPSPPESLRVVDETITTLRIEWDSPASGLYRGFEVDISPPTALQELPRIVG Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA -------RSTPSPSNTSQGAVTPSSSEASIPTRVSSSSVPSEEVNQTP------------ Dmel_Ptp10D.AA LTWTVTITTAPDPPSNLSVQVRSGKNAIILWSPPTQGSYTAFKIKVLG------------ Dmel_Ptp4E.AA LTWTVNITTAPDPPANLSVQLRSSKSAFITWRPPGSGRYSGFRIRVL------------- Hsap_PTPRO.AA ------------MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQ------------- Hsap_PTPRB.AA AEVSVRSTRNTAPPQILTTFNAVPDGLVFLIRNTTEAFIRNAAENYS------------- Aque_Aque_PTPRB-1.AA ------------------------MSLRITWTELLEDDQNGVIIGYNI------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA -----------------AIGTRASSLINLVAVPEAVGN---------------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------EEALIEDDVFLPDYIELSPKPKTKKKNVIHKNRVS------------- Spur_Spur_PTPRB4.AA --------MMNREEGLLDDDVFQPDYIELSPTPKTKKKNVIHKNRVS------------- Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA SDIRGFTFVGLMHNSEYTVSVTTIMGEEGLEERSTTAEKTVMTARGDGDEVYLLSVSSTD Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA AEIGWTSPPLTMGYLDGSQITVSGQRTRIPDLTPGRQYTFTVNDVDLTFTTVPERPDGLE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ---------------------------------------------CTGDGGTTETRNTTA Hsap_PTPRQ.AA -----------------------------KHARSGIVVKDVSIRVEDILTGKLPECNENS Spur_Spur_PTPRB2.AA ------------------------------------------ARPGVPALVEPNHSNGKD Hsap_PTPRJ.AA -----------------------------IPDP----------SVATVATGENGITQISS Cele_dep-1.AA -------------------------------------VTENISDEVRDSNKTFVSSDDAP Spur_Spur_PTPRB3.AA -----------------------------KEDPYQISDLFYVSDPSNPTIRLTGLSPLSE Spur_Spur_PTPRB5.AA LESVGPYSLDWKVDTSLNDLNYERLEVSYSPESSQTDSPFDISRCTDGTFTLEGLQPDTE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA -----------------------------SPSNTSQRAVTPSSSEASILTRVSSSSVSSE Dmel_Ptp10D.AA ------------------------------------------LSEASSSYNRTFQVNDNT Dmel_Ptp4E.AA ------------------------------------------GLTDLPFERSYSLEGNET Hsap_PTPRO.AA -----------------------------DDNNIVVSLEASDVISPASVYVVKITGESKN Hsap_PTPRB.AA -----------------------------QNSSERQHPNLHMTGITDTSWVLSTTQPFSS Aque_Aque_PTPRB-1.AA ------------------------------------------SYFSLPAVGQPINNFTSD Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ---------------------------------------------------RPILLTDID Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA TNVTVDGLGPGSLYTCSVWVEKDGVNSSVGTVTTA------------------------- Hsap_PTPRQ.AA ESFLWSTASPSPTLGRVTPPSRTTHSSSTLTQNEI----------------SSVWKEPIS Spur_Spur_PTPRB2.AA SYIALTLFTVPSCPALVIPASE-------------------------------------- Hsap_PTPRJ.AA TAESFHKQNGTGTPQVETNTSEDGESSGANDSLRT----------------PEQGSNGTD Cele_dep-1.AA YSIRIHALRAGHRYSIAIHGQKDGSTSL-------------------------------- Spur_Spur_PTPRB3.AA YIITLTSFSGSGSDQEISSSTVEASTASSYVIEAS----------------DAGNVVHST Spur_Spur_PTPRB5.AA YSVSVTAISGDTRSDVLTRYGFTTCALEGQLHVVSLSSDEIALAWGPVNNIQGYAVRLFN Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA EVNQTTSEEPSKTPIPGEPGLRSSPRVASEYSVTT----------------IDVMTEGNT Dmel_Ptp10D.AA FQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNF------------------------- Dmel_Ptp4E.AA LQLSAKELTPGGSYQVQAYSVYQGKESVAYTSRNF------------------------- Hsap_PTPRO.AA YFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVN------------------------- Hsap_PTPRB.AA TTEETGLAEPERCNFTLAESKASSHSVSIQWRILG---------------SPCNFSLIYS Aque_Aque_PTPRB-1.AA TSYNISGLDVYTDYNVSVAAYTSAGTGPFDSVIRR------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA THYDWLKADSENGLMKEYDGTGRGKFVQRLLGDCT------------------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA --------------------------------------------------TAPNPVRNLR Hsap_PTPRQ.AA F--------------VVTHLRPYTTYLFEVSAATTEAGYIDSTIVRTPESVPEGPPQNCV Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA G-----------------------------------------ASQKTPSSTGPSPVFDIK Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA S-----------RALSQSRFIIISNLTPGTLYTIRITVTGSSERDTEIALTVPTAPRSLS Spur_Spur_PTPRB5.AA AIGINMRTLSLSANSMSATLDSLSPASNYSVQLIVMDTDGSRQTSVLQFVTDPAPPGPIT Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA S-----------------------------------------------SKSSATNGIAID Dmel_Ptp10D.AA -------------------------------------------------TTKPNTPGKFI Dmel_Ptp4E.AA -------------------------------------------------TTKPNTPGKFI Hsap_PTPRO.AA ---------------------------------------------------------GNV Hsap_PTPRB.AA SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVS Aque_Aque_PTPRB-1.AA -----------------------------------------------TDSTVPTSPSDVS Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ----------------------------------------------------------IS Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA --------------------------------------------------------KIEK Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA VEAQTNSSIALTWEVPDGPDPQNSTYG-VEYTGDGGRAGTRSTAHT-------------- Hsap_PTPRQ.AA TGNITGKSFSILWDPPTIVTGKFSYRV--ELYGPSGRILDNSTKDLKFA-------FTNL Spur_Spur_PTPRB2.AA ---VTSMEIVATWPRPEGYTNVESYSI--SITPRTGVTYDSQIPNPFTSTNDMH------ Hsap_PTPRJ.AA AVSISPTNVILTWKSNDTAASEYKYVV--KHKMENEKTITVVHQPWCN--------ITGL Cele_dep-1.AA ---IKEESVVMDPRAPDFRSMDSDIQVAEHNITMRTIKNDSYLQDSFSIE------YRQI Spur_Spur_PTPRB3.AA TDSISQSIVTVSWSQGLGNVDEYDIYL--RQAGESETPAQIVPPSQLTET------FENL Spur_Spur_PTPRB5.AA LQSSTQTRLSFTWTPATSNFDSYELSISGGDMPEPRPVGVVYPNEGNEFE------VGGL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA TDSSTPMAVLFTTLRKYDTSQDTDTQLPDTTSLDLTTVGKIVTRNPSDMPMTSVQ-VETT Dmel_Ptp10D.AA VWFRNETTLLVLWQPPYPAGIYTHYKV--SIEPPDANDSVLYVEKEGEPPGPAQAAFKGL Dmel_Ptp4E.AA VWFRNETTLLVLWQPPFPAGIYTHYRV--SITPDDAIQSVLYVEREGEPPGPAQAAFKGL Hsap_PTPRO.AA VTKPSRSITVLTKPLPVTSVSIYDYKP----SPETGVLFEIHYPEKYNV-------FTRV Hsap_PTPRB.AA KEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYT------FFNL Aque_Aque_PTPRB-1.AA YINISSTSIEVSWNPPTDFNGPNEGYVITYIRLESDTESMSTNRLTGT------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA VTQYATTTADVQWNLMQCSDCIYNYFL--------------------------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA FQCSSRAVSAASAQKSYGTSAAFVQSL--------------------------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA TPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLA------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA RPATSYVFSITPGIGNETW----------------------------------------- Cele_dep-1.AA NPDKKFPVLQILDIPEQKNL---------------------------------------- Spur_Spur_PTPRB3.AA EPDTYYSMRIVSVVRAQNLEQRSIPAVTNFTTQPRIINVVETGRNLRLSWANDFGNDILK Spur_Spur_PTPRB5.AA LPDTTYNVRIYSVFFESRSIASEASFNT---DEQILEFNVGSNQNLTVSWQVQEGAESYR Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA EPSSVYSLVTELPLVTDLPTGL-------------------------------------- Dmel_Ptp10D.AA VPGRAYNISVQTMSEDEISLPTTAQYR--------------------------------- Dmel_Ptp4E.AA VPGREYNISVQTVSEDETSSVPTTARYL-------------------------------- Hsap_PTPRO.AA NISYWEGKDFRTMLYKDFFKG--------------------------------------- Hsap_PTPRB.AA TAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYR Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ---------EVESTQVRITWKKPRQPNGIINQYRVKVLVPETGIILENTLLTGNNEYIND Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA YQLIYIEDKEGATSNSEFVDPSDAPLVTLMNLMPGQTYTLILTAVDTLGNRAQIASTTYT Spur_Spur_PTPRB5.AA LIYTTTNRNTNSIARPATSTSITIDNLLFGAIYNFRLATIAADGTEMEVANADFVQRWHI Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA LMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAA------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA PMAPEIVNIVEPMVGLYEGSAEMSSDLHSLATFIYNSHPDKNFPARNRAEDQTSPVVTTR Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------GDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLLESI Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA L-----------KPLRPTFTVNRRSPSAVSLLGNLLGGILKFFRIRVTPQVTGAGAGTPI Spur_Spur_PTPRB5.AA ITNLVVFHDALCGPLTPSTNISDIKATTALLTFSLREGIFDDYVVMLSSPTDSCGARQPV Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------MPTDVSQTMQTSLPSAQSTALSTDEQPLEVSTLFDGGTDGTPSAFDPV Dmel_Ptp10D.AA ------------TVPLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATTRRQS Dmel_Ptp4E.AA ------------TVPERVLNVTFDEAYTTSSSFRVRWEPPRTYSEFDAYQVMLSTSRRIF Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------GLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNIT Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA FTLSREACPELLLLDLYPNTMYTAQVFARTGERGLSLPSETTLQNFTTATVVNNEVEISK Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ----------------------------------------NITVDGLEPGCLYAF----- Hsap_PTPRQ.AA ----------------------NQYITDIAAEQL------SYVIRRLVPFTEHMISV--- Spur_Spur_PTPRB2.AA ----------------------------------------RAVFSSLTPAQTYVIEV--- Hsap_PTPRJ.AA ----------------------GSHEELTQDSRL------QVNISGLKPGVQYNINP--- Cele_dep-1.AA ----------------------------------------EFYLGNLNSGFDYSVRV--- Spur_Spur_PTPRB3.AA ----------------------NIDVLIPVEACP------EIELTGLIPNRDYQVTL--- Spur_Spur_PTPRB5.AA VGTNSLEIIWKTDNVDEYLLHYSGPDGPLMSDIVPYIEINYYTFGELTPGTQYSISVISL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ----------------------SLEATTRLDETF------FDTTEA--GTLPTTTVS--- Dmel_Ptp10D.AA ----------------------TVPRSNEPVAF-------FDFRDIAEPGKTFNVIV--- Dmel_Ptp4E.AA ----------------------NVPRAANGDSVY------FDYPDILEPGRTYEVVV--- Hsap_PTPRO.AA ----------------------------------------KTVFNHWLPGMCYSNITF-- Hsap_PTPRB.AA ----------------------LSHKGTIKESRVLAPWITETHFKELVPGRLYQVTV--- Aque_Aque_PTPRB-1.AA ----------------------------------------SFVIENLEKYEQYSVTV--- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA --------SMWVGKNGINSSRETRNATTAHNPVRNL-RVEAQTTSSISLSWEVPDGTDPQ Hsap_PTPRQ.AA --------SAFTIMGEGPPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNGK Spur_Spur_PTPRB2.AA --------TANAINAGPESPAGCNSIPVVAKPAAVVLQVANFNTTSVSLAWSVPLSVTPD Hsap_PTPRJ.AA --------YLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESLVGPV------- Cele_dep-1.AA --------IAHKDGMSSRPWISTLTTKP---SPLKEVNINQNAGSCVEVSWQNDEFSGAD Spur_Spur_PTPRB3.AA --------QAESGVASSDPQIITFTTPPL--TQQGELSFGEITPSGFTVYWTP------- Spur_Spur_PTPRB5.AA INRERQGDALEVMQYTKPDPISNLVLTPQENTINLTWTSPSTMYDGFLICWYSATTEDNK Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA --------PLEVGSIGTIEAVTDLGMTEETNPATDLQEMETDLLTGEEVEGTPPLELWTI Dmel_Ptp10D.AA --------KTVSGKVTSWPATGDVTLRPL--PVRNLRSINDDKTNTMIITWEADPASTQD Dmel_Ptp4E.AA --------KTIADNVNSWPASGEVTLRPR--PVRSLGGFLDDRSNALHISWEPAETGRQD Hsap_PTPRO.AA --------QLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQS Hsap_PTPRB.AA --------SCVSGELSAQKMAVGRTFPD---KVANLEANNNGRMRSLVVSWSPPAGDWEQ Aque_Aque_PTPRB-1.AA --------VAFTDKGPGASSDVLSVLTDEDLPGPPSNVSTMSTNTSISITWSPPLDPNGL Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------LTFEPDSQEPIRVDYTT------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA --------RGEGAMTVQARPAERSARVLRAMPVRGMFNATSDMSTGYGLTIQA------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA -----------------------------------------NSTYCVQCTGDGGRTETRN Hsap_PTPRQ.AA --------------------ITHYTIYAMELDTNRAFQITTIDNSFLITGLKKYTKYKMR Spur_Spur_PTPRB2.AA ---------------------------------------GYVLTIDILSADADPAPVDIP Hsap_PTPRJ.AA -----------------------------------------------------DPSSGQQ Cele_dep-1.AA ---------------------------------------FYTIQYSLQSTPNNSTNMTIP Spur_Spur_PTPRB3.AA ----------------------------FLGRTSYELSINNQAGLVVPASGDAVQSYVVD Spur_Spur_PTPRB5.AA AWLDGDATTYPWVISTPNEEYVVSVATFVGDREGDYVLSNKVTDFITLTETSPLILKDIA Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ---------------------------ETSSEEVTEFDFPNDLSTELMASTEATTTIETP Dmel_Ptp10D.AA ---------------------------------------EYRIVYHELETFNGDTSTLTT Dmel_Ptp4E.AA -----------------------------------SYRISYHEQTNASEVPAPFPVAAES Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP Aque_Aque_PTPRB-1.AA -------------------------------------LLSYSINVTLNSTYAQYLSFDVM Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA TTDTR------------------------------------------------------- Hsap_PTPRQ.AA VAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTADEIRLKWSPPEKP------ Spur_Spur_PTPRB2.AA GADTA------------------------------------------------------- Hsap_PTPRJ.AA SRDTE------------------------------------------------------- Cele_dep-1.AA STESSI------------------------------------------------------ Spur_Spur_PTPRB3.AA GLSSGTEYTVSLVDGGTGAIRTRPLAPGTPLATQVLDTSIQLQWAQSSDGNVAG------ Spur_Spur_PTPRB5.AA TDTISVSWVTIPGVVDYTLSYSPPDGNEQATQDIDESSAIAEGLNNIYYVNFTGLTPGRE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA VIPAP------------------------------------------------------- Dmel_Ptp10D.AA DRTR-------------------------------------------------------- Dmel_Ptp4E.AA QITTNLTE---------------------------------------------------- Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKE-------- Aque_Aque_PTPRB-1.AA TMSVSQNIFS-------------------------------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA YTFTVVWPLAFNYSTDAIRTNPLPIYDPSVTNTTSCNLLYQWCLPDSDFDNISITIVPDV Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA SMRTLSRGNGTGGMCDYQTVYLDGLEPATSYNVSVEVMSGDKSSEVVMVYSTTEPLPVNN Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ---------------------------------------------------VTVDGLGPG Hsap_PTPRQ.AA -------------------NGIIIAYEVLYKNIDTLYMKNTSTTD------IILRNLRPH Spur_Spur_PTPRB2.AA ---------------------------------------------------YVVPSLLPG Hsap_PTPRJ.AA ---------------------------------------------------VLLVGLEPG Cele_dep-1.AA ---------------------------------------------------SICDSMLQG Spur_Spur_PTPRB3.AA -------------------YEICYSPDDGSSPVYIAGRTTTQ---------YTLEGLDSD Spur_Spur_PTPRB5.AA VTLDDSTIFTLTISWENPIDGSFNMFLVEYAPVRSPDSVMALDPINMGTNTAIIPNLQPG Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ----------------------------------------------------CLCDVESD Dmel_Ptp10D.AA ---------------------------------------------------FTLESLLPG Dmel_Ptp4E.AA ---------------------------------------------------YTLDSLLAG Hsap_PTPRO.AA -------------------------------------------------------GNFPE Hsap_PTPRB.AA ---------------------------------------------------FTFTDLVPG Aque_Aque_PTPRB-1.AA ---------------------------------------------------YTLFDLLPF Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ---------------------------------------------GVNEYSYQVSGLTEG Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ----------------------------------------------------------KY Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA SLYTCSVWVEKDGVNSSVEIVTSA------------------------------------ Hsap_PTPRQ.AA TLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDS-------------------------- Spur_Spur_PTPRB2.AA VEYSFTVQAYQNVQSTRAFGETDTVMQR-------------------------------- Hsap_PTPRJ.AA TRYNATVYSQAANGTEGQPQAIEFRTN--------------------------------- Cele_dep-1.AA EAYQIIATVQKGGQVSEPLITKFQLR---------------------------------- Spur_Spur_PTPRB3.AA TTYIISISALTGVPQVKSQKQTIFVTTIADTTIP-------------------------- Spur_Spur_PTPRB5.AA TLYNIMVYALAGEERSDATEITAMTRQQNSEELRLQTRTSTSISVSWGNTTRPEVTGFVL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA LLSASVCLCNTSLALSNFTYRAHLVRRNHD------------------------------ Dmel_Ptp10D.AA RNYSLSVQAVSKKMESNETSIFVVTR---------------------------------- Dmel_Ptp4E.AA RRYLIAVQALSKGVASNASDITRYTR---------------------------------- Hsap_PTPRO.AA ESFMRSQDTIGKEKLFHFTEETPEIPSGNI------------------------------ Hsap_PTPRB.AA RKYMATVTSISGDLKNSSSVKGRTVP---------------------------------- Aque_Aque_PTPRB-1.AA AGYDISLQASTSVGLGTPAIETETTLQ--------------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA RNYNFTVVSVSGVGVQDATLK--------------------------------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA EHSRVKLMALKGKSETDYINA--------------------------------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA RITFQEGDAIDSIKNVSLGDVLGVEFSDLIPGTNYTVYLLVEVEGQLDTAVHSLDVTTLP Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA -APENITYKNISSGEIELSFLPPSSPNGIIQKYTIYLKRSNGNEERTINTTS-------- Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA -AIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSE-------- Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA -VASNFAVTNTQAADHVIILEWDVPERASYDYFEVSYTPDVGYPSSPVRLPK-------- Spur_Spur_PTPRB5.AA GMPGNISCDPTKTTQSLLEIEWGSTQEGNFDGYAISTQTGDGEEIPLESVEKDEQLQATA Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA -NRTHPEVQVHAALISSGSGCWNISVPLGGS----------------------------- Dmel_Ptp10D.AA --PSSPIIEDLKSIRMGLNISWKSDVNSKQEQYEVLYSRNGTSDLRTQKTKE-------- Dmel_Ptp4E.AA --PAAPLIQELRSIDQGLMLSWRSDVNSRQDRYEVHYQRNGTREERTMATNE-------- Hsap_PTPRO.AA -SSGWPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNS------------- Hsap_PTPRB.AA -AQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSET-------- Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA DYLMDNTIYTFIVRSTLGDLRGEPTTMTCRTDPQNLMVSTSTSPSGGQEVFLDWQDYGAS Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA SYKVEYTPQEGTPSSPIFLDTRQLILRNLSPGTAYHFTLHYTATGSTTGVTFVLAPLPVV Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------LTQNIK Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------PRAVIP Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------AATSLS Spur_Spur_PTPRB5.AA QVIIVLRRPTSFTIQITLPRRGRYRFLRLRVRRRSQGLDAGPDGDEFLIPTDACPEYTFN Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA --------------------------------------------------------SRLV Dmel_Ptp4E.AA --------------------------------------------------------TSLT Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA --------------------------------------------------------SRYS Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ----------------------------------TAPNPVRNLTV-EAQTNSSIALTWEV Hsap_PTPRQ.AA VLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSV-KQLSGVTVKLSWQ- Spur_Spur_PTPRB2.AA ----------------------------------TTPVPPENIAI--EVTETTATITYEA Hsap_PTPRJ.AA GLRSS--TFYNITVCPVLGDIEGTPGFLQVH---TPPVPVSDFRV-TVVSTTEIGLAWS- Cele_dep-1.AA ------------------------------------PLPPIDFRVRADLKRGKYKLLAEL Spur_Spur_PTPRB3.AA IMNALADKVYQFSLVSIRGDERTDPPLTTTG---QIAVNNLIVVI-GERTTTSLEILWGA Spur_Spur_PTPRB5.AA NLLPDTDYAVDVNTVAEDGRTESSPSTMDVT---TPRMEEGDISF-NEVTTTSISFAWGM Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA -------YKLVVTAEDGLGNLVSTPTAYFYS---GLMPPFLSVKK-VPGAIPSLELYWQI Dmel_Ptp10D.AA IKNLQPGAGYELKVFAVSHDLRSEPHAYFQA---VYPNPPRNMTI-ETVRSNSVLVHWSP Dmel_Ptp4E.AA IHYLHPGSGYEVKVHAISHGVRSEPHSYFQA---VFPKPPQNLTL-QTVHTNLVVLHWQA Hsap_PTPRO.AA ----------------------------------TLSETEKSTSGSFSFFPVQMILTWLP Hsap_PTPRB.AA FHSLKSGSLYSVVVTTVSGGISSRQVVVEGR---TVPSSVSGVTVNNSGRNDYLSVSWLL Aque_Aque_PTPRB-1.AA ----------------------------------AAPAAPVANPMASPVSSTAVNVSWLP Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ----------------------------------TSEEESVDQ----------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA PDGP--DPQNSTYGVEYTGDGGRAGTRSTAHTN--------ITVDR-------------- Hsap_PTPRQ.AA PP-LEPNGIILYYTVYVWNRSSLKTINVTETS---------LELSD-------------- Spur_Spur_PTPRB2.AA P----------------------------------------------------------- Hsap_PTPRJ.AA ------SHDAESFQMHITQEGAGNSRVEITTNQS-------IIIGG-------------- Cele_dep-1.AA PT----SSKIDKCQITVAGDEAERSVNYANIEQTKSGHKICWFNFA-------------- Spur_Spur_PTPRB3.AA SA-S---GSVDEYQVSYVGSTPIVVDGSSDRR---------VVIPG-------------- Spur_Spur_PTPRB5.AA VS-ADTNGPFDFYLLNLKNELSIDVQNVQVNTSETREHTFIGLMPGELYRVELIVNSNRQ Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA PY-P---TYVDDVTIFVSKDDALATELTWMRVGGVRTSGQ-FTFVA-------------- Dmel_Ptp10D.AA PE----SGEFTEYSIRYRTDSEQQWVRLPSVRSTE------ADITD-------------- Dmel_Ptp4E.AA PE----GSDFSEYVVRYRTDASPWQRISGLHENE-------ARIKD-------------- Hsap_PTPRO.AA PKPP---TAFDGFHIHIEREENFTEYLMVDEEAH-------EFVAE-------------- Hsap_PTPRB.AA AP-----GDVDNYEVTLSHDGKVVQSLVIAKSVRE------CSFSS-------------- Aque_Aque_PTPRB-1.AA PNLSNWNGLITNYTIEYRTNDEY------------------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA -----------------------------------------NYIPG-------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA RSAPMYTRPDKPTDIMLSDLTTTSLTIDWKAPLTSYQGFRLCWAYGETNSLELGPAVMER Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ----LEPGCLYVFSVWVGKNGINSSRETRNA----------------------------- Hsap_PTPRQ.AA ----LDYNVEYSAYVTASTRFGDGKTRSNIISFQTPE----------------------- Spur_Spur_PTPRB2.AA ----LGFHSNFTHTLLDDGGNE-------------------------------------- Hsap_PTPRJ.AA ----LFPGTKYCFEIVPKGPNGTEGASRTVCN---------------------------- Cele_dep-1.AA ----LSPGERFDFSISSMANESASQKLQKSI----------------------------- Spur_Spur_PTPRB3.AA ----LSPGTEYTVTVQAINAGAAVGDSMETASTLHEINGLSAMVTDQASSMIHLTITPPF Spur_Spur_PTPRB5.AA TLSDLEAGAEYLVSLAAVVGTGANQITSEKFTTIVTLFPPAELHVNITSFNTTAVSIVWG Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ----SGLGSKYSVAVVIASGAKSVTSNYDTV----------------------------- Dmel_Ptp10D.AA ----MTKGEKYTIQVNTVSFGVESPVPQEVN----------------------------- Dmel_Ptp4E.AA ----MHYGERYLVQVNTVSFGVESPHPLELN----------------------------- Hsap_PTPRO.AA ----LKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWI-------------- Hsap_PTPRB.AA ----LTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATG Aque_Aque_PTPRB-1.AA ----IRPSIEVTATLSSFANSDDPRA---------------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA EDPMRYDGYNVRVRLGGVSSPVVQPVIPVAKSACPEIWIKKLEAATMYEIDIEWYSGLDI Spur_Spur_PTPRB5.AA TDIPLLDVSSYVVSYWETANNGSVQDISVDDPSQTDYTIDGLVPGTRYSFMVDALGTVQA Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA DFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNG-- Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA --------TTAPNPVRNLHMETQ--TNSSIALCW-------------------------- Hsap_PTPRQ.AA --------GAPSDPPKDVYYANL--SSSSIILFWTPPSKPNGIIQYYSVYYRNTSGTFMQ Spur_Spur_PTPRB2.AA --------VRGPDGSNEFSVEYM------------------------------------- Hsap_PTPRJ.AA --------RTVPSAVFDIHVVYV--TTTEMWLDW-------------------------- Cele_dep-1.AA --------VLTPAFDFNAFGLTLQESNGGIELIW-------------------------- Spur_Spur_PTPRB3.AA SEAFRVQTSTVAAAPLDITLDEL--ETDSMKVSW---QEGTGSFSNYLVTYSPVGSTQTP Spur_Spur_PTPRB5.AA VTSIGATQYTNPETVAEIRVIPS--ITCSVRLEW---DRPEGNLDSYIFHYNVTRGTIVG Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA --------VIAPQHPHTVRVASI--SSELLTMQWPHDPSSCTAACSYLVRYQ-------- Dmel_Ptp10D.AA --------TTVPPNPVSNIIQLV--DSRNITLEW---PKPEGRVESYILKWWPSDNPGRV Dmel_Ptp4E.AA --------VTMPPQPVSNVVPLV--DSRNLTLEW---PRPDGHVDFYTLKWWPTDEEDRV Hsap_PTPRO.AA --------EELTEKPQHVSVHVL--SSTTALMSWTSSQ---------------------- Hsap_PTPRB.AA --------RTIPEPVKDLTLRNR--STEDLHVTW---SGANGDVDQYEIQLLFNDMKVFP Aque_Aque_PTPRB-1.AA --------ATTPLQLESIIIPSL------------------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ----------MPAYITAIDIPYP------------------------------------- Spur_Spur_PTPRB9.AA --------RTVPATPSDLSIVP---GQRELNLVW-------------------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA --------FNSPREYIACQGPLPETTNDMWRMIW-------------------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA NFTLHEVTNDFDNMTVSTI----------------------------------------- Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA MLVAKGEPRVLDLSGLVPGTAYTIMVQQQGQTPAQETHVQLTLPEAINIDSLSVTRSKNA Spur_Spur_PTPRB5.AA APLQLDVAINDTAETLTYLLEGLEKDSSSDFVSLEVGVTTVAGAGEDQVESLQQVVKDLD Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA QTKNVSENKSADDLSTVRVL---------------------------------------- Dmel_Ptp4E.AA EFKNVTQLEDLSSPSVRIP---IEDL---------------------------------- Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA -----------------EVPDGPYPQDYTYW----------------------VEYTGDG Hsap_PTPRQ.AA ------------IDKLTIFSYYTFWLTASTS----------------------VGNGNKS Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA -------------KSPDGASEYVYHLVIESK----------------------HGSNHTS Cele_dep-1.AA -----------------PKSEVFMTRVKDIW----------------------NKVVGAE Spur_Spur_PTPRB3.AA LDATWSAPS---TGNYDGYRVCHYPRGTQNS----------------------PFTSGTT Spur_Spur_PTPRB5.AA VNVVTITILGRDQNSIQAEVNSSVSNVESIT----------------------TGLYNDE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------QTSPYNYNSNPVTELPVRC----------------------PGLLAAQ Dmel_Ptp10D.AA ------------IGELMPGVQYKFDIQTTSY-----------------------GILSGI Dmel_Ptp4E.AA ----------------SPGRQYRFEVQASSN-----------------------GIRSGT Hsap_PTPRO.AA ----------------ENYNSTIVSVVSLTC----------------------QKQKESQ Hsap_PTPRB.AA SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA -----------------EKKSTIIVMMTQTV----------------------EGGK--- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA GGTETR------------------------------------------------------ Hsap_PTPRQ.AA SDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTPRH-- Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA T----------------------------------------------------------- Cele_dep-1.AA SLLNMRITPIGNNDETDKTLKFE------------------------------------- Spur_Spur_PTPRB3.AA PSINLPGLNSLTYYLVTVSSSEESTYSEPTTITQQTLIGDPGDINIALEDVDTNSVRITW Spur_Spur_PTPRB5.AA MVTSSTTRNCSTTDCESFTVDFDTLNSGTLYTLYAGVVQSSGREVVPLLAKAATIPESAV Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA PARSTS------------------------------------------------------ Dmel_Ptp10D.AA TSLYPRTMPLIQSDVVVAN-GEKEDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRD-- Dmel_Ptp4E.AA THLSTRTMPLIQSDVFIANAGHEQGQDETITLSYTPTPADSTRFDIYRFSMGDPTIKD-- Hsap_PTPRO.AA RLEKQY------------------------------------------------------ Hsap_PTPRB.AA LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRN-- Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA VAINSITR---------------------------------------------------- Spur_Spur_PTPRB5.AA DLQFTSIGRNYVVLTWDNPAGMIDSYNISYYPVNDITKLMFEVVQAAAESNVLRVDDLNE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA GMNYSFTVVSLLEVEADLQEMGAPVEVFAVVGVLGSLNITAFDETTISIEWEQVDVEEYI Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ----------------NTTNTSVTAERLEPGTLYTFSVWAEKNGARGSRQNVSISTV--- Hsap_PTPRQ.AA -----------VRPPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEE Spur_Spur_PTPRB2.AA --------------------------DLTAGTMYTYRVLSNAGSATSEAVLQTFTSR--- Hsap_PTPRJ.AA ------------------YDKAITLQGLIPGTLYNITISPEVDHVWGDPNSTAQYTR--- Cele_dep-1.AA --------------TSPKNIDPVFAKNLVKGACYRVQLFTVTKTGIISETRHNETIR--- Spur_Spur_PTPRB3.AA YTVGGGTGASQTVTVNSPEEAEYTFTNLVPGTSYTFFVTP-----LGTQRREREQYT--- Spur_Spur_PTPRB5.AA LSYDALEGGSGNVTVQSTDPNSYTFTGLTPGTQYTIGVQPGIYAALEKTQSTV------- Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA --------------PNAMNTCTEYLRDLIPGALYDIDVYASSYGVLSVTAAQLRQRT--- Dmel_Ptp10D.AA -----------KEKLANDTDRKVTFTGLVPGRLYNITVWTVSGGVASLPIQRQDRLY--- Dmel_Ptp4E.AA -----------KEKLANDTERKLSFSGLTPGKLYNVTVWTVSGGVASLPVQRLYRLH--- Hsap_PTPRO.AA --------------CTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAI--- Hsap_PTPRB.AA -------------TSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTV--- Aque_Aque_PTPRB-1.AA ------------------------------HEFVNYSFIITLSNSIGQISSLPVHIVTLE Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA --------------------------NKMKREVIQLQFTSWPDHGVPEQTKPMLDFV--- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ---PNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTD-- Hsap_PTPRQ.AA DVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFITSDNY---- Spur_Spur_PTPRB2.AA ---PNPPGIPEPTFVDETTITIQWAHN-SGERDEYEVSYSPNGTSFTPQTPQYVIENR-- Hsap_PTPRJ.AA ---PSNVSNIDVST-NTTAATLSWQNF-DDASPTYSYCLLIEKAGNSSNATQVVTDIGIT Cele_dep-1.AA --MSSPAVNVSLESVTRSSATLRIVFSTHHDSTSISNCQMHIVVRDMNGKSVFDKRMQLT Spur_Spur_PTPRB3.AA --RPDMPRNLLFNTITTNSISIGWEKPLTGGVDSYRVTYSPSSDGSPASPHTITDNGQIT Spur_Spur_PTPRB5.AA ---PNPPTNLRTTMVAAQSITVSWDPPSEGGSDTYNITYNVTGGQPPSPHTVSTSETS-- Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA --PPTPPQNVTVTNVTEQSITIAWTPGAGYRTRYHLHAYATSYSEEVGVVHGDVTD---- Dmel_Ptp10D.AA ---PEPITQLHATNITDTEISLRWDLP-KGEYNDFDIAYLTADNLLAQNMTTRNE----- Dmel_Ptp4E.AA ---PLPISDLKAIQVAAREITLHWTAP-AGEYTDFELQYLSADEEAPQLLQNVTKNTE-- Hsap_PTPRO.AA --VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAAT Hsap_PTPRB.AA ---PAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS--- Aque_Aque_PTPRB-1.AA STPSGPPLDVSVIVDSPSTARISWSPPMYIDRNGIIVNYTVRIITTVRGTIRETNISNVS Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ----------------------------AYQGDADNFTITVTPNQGIAMFNGDFNDPA-- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ----KNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVC------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------ITLKELEAGSLYHLTVWAERNEVRGYN--------------------------- Hsap_PTPRQ.AA ------IILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSD Spur_Spur_PTPRB2.AA ------FVLTGLDPYTTIQFDVRTVVNSVTSTP--------------------------- Hsap_PTPRJ.AA D-----ATVTELIPGSSYTVEIFAQVGDGIKSL--------------------------- Cele_dep-1.AA ATFAPLLNLDGLSPFHKYTVNTQIICGSGSSET--------------------------- Spur_Spur_PTPRB3.AA QT----LTVTNLLPGTTYTFNVYALVAELVSEP----VTRGSGTTIGMDIGAGYTSTQFT Spur_Spur_PTPRB5.AA ------VTFSNLTPLTEYFFTIVNIWKSLPSRS--ELTRATTSAQTLSLAVTPEDNTEFT Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------FTFHNLLAGTRYIITIRASANDTDGDM--------------------------- Dmel_Ptp10D.AA ------ITISDLRPHRNYTFTVVVRSGTESSVL--------------------------- Dmel_Ptp4E.AA ------ITLQGLRPYHNYTFTVVVRSGSIQGTD--------------------------- Hsap_PTPRO.AA VSLTASVRIANLLPAWYYNFRVTMVTWGDPELS--------------------------- Hsap_PTPRB.AA ------FSFQNLLQGRMYKMVIVTHSGELSNES----FIFGRTVPASVSHLRGSNRNTTD Aque_Aque_PTPRB-1.AA GNY---YDASDLPQFASFNVTVAAATSVGLGPY--------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------AEVTGLTPGTMYDIAIVTASGDERSEP--------------------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------GVVCEMRMHRNYLVQTEVDSSRAGSHS--------------------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA FVWLKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSA Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA VVWNVPTSGDFNQFQVTYDPYDPTNAQESPRIISLSSLNGAQEGSLLIYGLEPGQLYNVY Spur_Spur_PTPRB5.AA VSWEDLDTEAFEQYCVMYEPYEAQENRQQESF--PVARNIRSARFYGLDPGQEYTVYVTS Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA SLWFNWSPASGDFDFYELILYNPNGTKKE------------------------------- Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA FTKVGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKANGIITQYMVTV Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA VQTMLNGLQTDDGFGRISFRTPPLPVTGVVITQRTPYSLSLDWSDVISADIQYRITYAPL Spur_Spur_PTPRB5.AA CSSVSDPTSHANERISFRLDPAAIAEIRIMDGSLGPRAVMLEWDQPEGIRGLYEVTLDPA Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ERNSTKVSPQDHMYTFIKLLANTSYVFKVRASTSAGEGDESTCHVSTLPETVPSVPTNIA Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA EGALFPNNEDSAQVLSSNQVSESQISARSLAPGKEYVFTISPVSGDPSSFEQVGEPETVV Spur_Spur_PTPRB5.AA DEGSVDVDGDELPVNITGVMTSIKILNLAAGKG-------YTVGITAISGDKRSENTTFL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA FSDVQSTSATLTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLT Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA TYTQPLSPQNLVVSDVGVEEVSLSWNLPAEVNFPIAYYEIDLVPNEPTFPIRINGTRDKW Spur_Spur_PTPRB5.AA FYTLPDPPQNLVISEIGEDTATLSWADPAEMNFDILEVVMTTMPATKTTILKLNTNTVEL Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA -------------------------------------------------------NWKDK Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ---------------------------------STLTAATAPNEVTDLQ----------- Hsap_PTPRQ.AA EETVYGLKKFRWYRFQVAASTNAGYGNASNWISTKTLPGPPDGPPENVH----------- Spur_Spur_PTPRB2.AA ------------------------------TTWRQRTFAARPNMIENL------------ Hsap_PTPRJ.AA -------------------------------EPGRKSFCTDPASMASFD----------- Cele_dep-1.AA --------------------PQCPAATRTMRQLSFSTRQDKPAAVQDLK----------- Spur_Spur_PTPRB3.AA EIHDGLVSGGEYQAVMRSVINDVNGQVIYSEPLQSAFFLLEPTQPQRLSTPYVTTTELRV Spur_Spur_PTPRB5.AA TNLVPGQTYTVQLASVIRPDDALNQPEVIGEPQVSSPFLMKPASPSDIS----------- Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------VPVGETTLPTKPGPVDRLR----------- Dmel_Ptp10D.AA -------------------------RSSSPLSASFTTNEAVPGRVERFH----------- Dmel_Ptp4E.AA ----------FADVSVSTLMRSSAP-----ISASYQTLTAPPGKVDYFQ----------- Hsap_PTPRO.AA -----------------------------CCDSSTISFITAPVAPEITS----------- Hsap_PTPRB.AA DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFAD----------- Aque_Aque_PTPRB-1.AA -----------------------------SPSVSNMTFEGVPSAPDPVI----------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------ITQTNRTLPDKPSPVGNPQ----------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA EWTLGNSNFTTFQVSFSKDSATILTTDTTEQSLLLTNLTVATVYDISIRTVVEGPQTNMI Spur_Spur_PTPRB5.AA ------------------------------------------------------------ Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ----------------------NETQTKNSVMLWWKAPG--------------------- Hsap_PTPRQ.AA ---------------------VVA-TSPFSISISWSEPAVITGPTCYLIDVKSVDNDEFN Spur_Spur_PTPRB2.AA ---------------------MIVTTSASSVNVVFNVPT--------------------- Hsap_PTPRJ.AA ---------------------CEVVPKEPALVLKWTCPP--------------------- Cele_dep-1.AA ----------------------VEPLNSYSVMLTWLPPA--------------------- Spur_Spur_PTPRB3.AA KTSAAALIMAVTTKSKPPQNLMQDEVTSDSITVSWGAPLNVVNMYHIIVKDEDGADVADA Spur_Spur_PTPRB5.AA ----------------------VSNNELTRVTVTWQPSEGVVARYSYTYGLPGSTVTASE Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ---------------------LEPQIDHRQIRLAFLAPM--------------------- Dmel_Ptp10D.AA ----------------------PTDVQPSEINFEWSLPS--------------------- Dmel_Ptp4E.AA ---------------------PSD-VQPGEVTFEWSLEP--------------------- Hsap_PTPRO.AA -----------------------VEYFNSLLYISWTYGD--------------------- Hsap_PTPRB.AA -------------------------IANTSLAITWKGPP--------------------- Aque_Aque_PTPRB-1.AA ----------------------VKRRNDTAIQVNWTRPA--------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ---------------------AEA-VDKNTITLTYESPL--------------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA --------------------------MNYGILLEIA------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ISFIKSNEENKTIEIKDLEIFTRYSVVITAFTGN--------ISAAYVEGKSSAEMIVTT Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA TVPSSETSYTIENLNPYTKYIITVAARFNGLDSD--------AIEIEQTTFQGKPSVVRD Spur_Spur_PTPRB5.AA TTTTTDTSIQLSNLTPSTRYEFRLWAESDQTEGSETSSSDVVTVNIVTTVFFNVPSDPVS Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ----DWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWK Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA -----------------------------------DPHSQLYVYWVQWASKGHPRR--GQ Hsap_PTPRQ.AA LESAPKDPPNNMTFQ---KIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIH Spur_Spur_PTPRB2.AA -----------------------------------KPNGLITGYLISYNGMRNTAT---S Hsap_PTPRJ.AA --------------------------------------GANAGFELEVSSGAWNNA---- Cele_dep-1.AA -----------------------------------LPNGILTHYAVNVTKIGSDET---- Spur_Spur_PTPRB3.AA PVVAINSPNSVF----------------LTWTPPDSPNGILTGFVVEITGEDLTSR--KR Spur_Spur_PTPRB5.AA ALPVTTLPSMPSAVGGLTITKTGIVDAEVSWSSPLLPNGVIANYSLTIHISHDNGT-LSP Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA -----------------------------------LPNGVLEGYRVEYVGKRNGSR---- Dmel_Ptp10D.AA ----------------------------------SEANGVIRQFSIAYTNINNLTD---- Dmel_Ptp4E.AA ----------------------------------AEQHGPIDYFRITCQNADDAAD---- Hsap_PTPRO.AA -------------------------------DTTDLSHSRMLHWMVVAEGKKKIKK---- Hsap_PTPRB.AA TYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEV---- Aque_Aque_PTPRB-1.AA -----------------------------------EPNGIILGYLIYYIGTKNNTGTEYS Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA -----------------------------------EPNGDITGYRISYIGTRD------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA -----------------------------------ERHFVLVAFLILVRRVRVSTMLRHR Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA DPQANWVNQTSRTNETWYKVEALEPGTLYNFTVWAERNDVASS----------------- Hsap_PTPRQ.AA NLSIIQKTNTF----VIAMLEGLKGGHTYNISVYAVNSAGAGP--KVPMRITMDIKAPAR Spur_Spur_PTPRB2.AA SGNQFFSDIHPNDVRVEVPIASLDPGYVYQFSVQAVNGEGTSD--AVIGEVTLVAGGNGI Hsap_PTPRJ.AA --THLESCSSENGTEYRTEVTYLNFSTSYNISITTVSCGKMAA--PTRNTCTTGITDPPP Cele_dep-1.AA RTIDVGVSSNRSDHTVQVVIDELFGGHTYSFSVRAVTEAGFGENSPVVPTVSMPLMAPPV Spur_Spur_PTPRB3.AA REAGFTRTETYGVTVFSATIENLPTGCSYTFSIKAANSADQSD--AVIAGPLDLPHSAPP Spur_Spur_PTPRB5.AA YGDTVTISAVAEQTEYSQDVIGLAAGQYYVFSVYATNQVASSN--QRSTTRTLFAETAPP Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA --TCSSGQKYLPVVETSVIIEGLKGGCYYTFTVKARNEVGLGP--GASDSVLTAIGIPQV Dmel_Ptp10D.AA -----AGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFGP--EREYRQTMPILAPPR Dmel_Ptp4E.AA -----VSSYEFPVNATQGKIDGLVPGNHYIFRIQAKSALGYGA--EREHIQTMPILAPPV Hsap_PTPRO.AA ----------SVTRNVMTAILSLPPGDIYNLSVTACTERGSNT------SMLRLVKLEPA Hsap_PTPRB.AA -----EFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSE--VVEDSTITMIDRPPP Aque_Aque_PTPRB-1.AA NINVLIIINVTDPNTLSYLITNLLADTQYFINVTAYTSAGLGAVGDGDSILLPTGRPPTV Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA --------------------------------IIAVNDGGFES-DPALTEPVETPQEEPS Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA NQAPLQGEDEAPKTTPSPIIARYVSKEYAPLPL--------------------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ---------------------------TQSLCASTYPDTVTITSCVSTSAGYGVNLIWSC Hsap_PTPRQ.AA PKTKPTPIYDAT-GKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKW Spur_Spur_PTPRB2.AA NAQGATAS---------SSATTITIVINDNLFSDVNGAVIALQVFVAEEHASNTDRTISD Hsap_PTPRJ.AA PDGSPNIT----------SVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAGHPSADVLK Cele_dep-1.AA PTVAPMIM------KESVGSHNMIVRFPTTMFDNRNGEIKQFAIIVSETTADESINRWIE Spur_Spur_PTPRB3.AA TPPADRVV-----RLVSHTGTTMSVSFDSSIFSDVYGPVTRYALLVAQSSPDTIPSTPSD Spur_Spur_PTPRB5.AA SPPRGATP------SLVSRGSTITITF-FNLFDTAFGRIVRFAIIVQERVDGGTVVITAK Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA PDARPLPP-----PSKTIRSRNFVVNFDPSIFDDVNGEITHVIVIVAQSSDTRRKRSVAA Dmel_Ptp10D.AA PATQVVPT------EVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMP Dmel_Ptp4E.AA PEPSVTPL------EVSRTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDVGKNASGLEMP Hsap_PTPRO.AA PPKSLFAV--------------NKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEP Hsap_PTPRB.AA PPPHIRVN----EKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQ Aque_Aque_PTPRB-1.AA PPNVTIGTPPTGGTSDPTTATTIRIEVTIPEELNANGPLTRIRILIRIFLSRNDTISTWY Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA PVPEDYPYEANT-VFSETSTTSFAVVLPDDLFSHENGELLTFAVIITIDDNDPTVSSTEL Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA -------------LEVFIYAAFIITVFSRAFFAVYEASKEYKDVLYSFNFEEGWYIFWHK Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------PQGGYEAFELEVGGQRGSQDRSSC Hsap_PTPRQ.AA ------YDAYFNKARPYFTNEGFPNP-P----CTEGKTKFSGNEEIYIIGADNACMIPGN Spur_Spur_PTPRB2.AA PPRRYQQVRDLLFRTAYVTSPLFAPTPF----GGRRKRQIADTLTSYTIGSEREC---VS Hsap_PTPRJ.AA ------YTYEDFKKGASDTYVTYLIR-T----EEKGRSQSLSEVLKYEIDVGNES----T Cele_dep-1.AA ---SDNGTYTWQQVQRFDVWPSYVAKLQ----DIQKVKQDVDVSIFEELGEDETC-LEVR Spur_Spur_PTPRB3.AA ----------PAINWQVGSGQPYQTT-L----LTYAPFTNGNTRGFYTVGANNSC--TQD Spur_Spur_PTPRB5.AA --RQTTSSLTWAEARRTRPVPSYQTT-P----DDYNPFADGAGVTTFRVGSQSCD--PDD Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------TTPTTPTITKIDIGTEECS--YET Dmel_Ptp10D.AA SWLDVQSYSVWLPYQAIDPYYPFENR----------------SVEDFTIGTENCD---NH Dmel_Ptp4E.AA SWQDVQAYTVWLPYQAIEPYNPFLTS--------NGSRKSSLEAEHFTIGTANCD---KH Hsap_PTPRO.AA --------------------------------------------------------VAVS Hsap_PTPRB.AA HPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLG-GKCD---PT Aque_Aque_PTPRB-1.AA ----------ESQKFPNSVAPPWQATQLPLNQGNRRKRQAGGETVAETIGTNNSC---GP Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ----------------------YPPS-F----GSNRKRRATEPSATVVIGNGTCA---GS Spur_Spur_PTPRB9.AA ---TYAARAENAYITAIEIPYPYSPS-F----GSNRRRRATDPPGTVVIGDGTCA---GS Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ----------------------------------------DKDIGDFEWT-------HWR Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA GEAVSVLGLGPARSYPATITTIWD------------GMKVVSH-----SVVCHTESAGVI Hsap_PTPRQ.AA EDKICNGPLKPKKQYLFKFRATNI-----MGQ----FTDSDYSDPVKTLGEGLSERTVEI Spur_Spur_PTPRB2.AA EDSICNGPLEPLTSYRVLVRAYT------DGG----FADSPWS-----EPISTRALDSWF Hsap_PTPRJ.AA TLGYYNGKLEPLGSYRACVAGFTNITFHPQNKGLIDGAESYVSFSRYSDAVSLPQDPGVI Cele_dep-1.AA ADRICNGPLRSASKYRVRIRLFTSPTL---------FTDSPPSQVMTTGSATPAIPLLTV Spur_Spur_PTPRB3.AA SVGYCNGPVVPLTDYRFALRAYGS-----DGK----FTDSAWS-----PLYNSGINTTWY Spur_Spur_PTPRB5.AA LTAYCNGALYPGTSYRFAIRAYGV-----DGK----FVDTEFS-----SPFRTDPDRGIF Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA KNVYCNGPLIQGRSYVYRFRGIS------PGG----YADTKNS-----LPVSLPMSPHGV Dmel_Ptp10D.AA KIGYCNGPLKSGTTYRVKVRAFTG-----ADK----FTDTAYS-----FPIQTDQDNTSL Dmel_Ptp4E.AA QAGYCNGPLRAGTTYRIKIRAFTD-----EDK----FTDTVYS-----SPITTERSDTVI Hsap_PTPRO.AA SHVVTISSLLPATAYNCSVTSFS-------------HDSPSVPTFIAVSTMVTEMNPNVV Hsap_PTPRB.AA QQKFCDGPLKPHTAYRISIRAFTQLFDEDLKE----FTKPLYSDTFFSLPITTESEPLFG Aque_Aque_PTPRB-1.AA NDIVCNGPLKPGTQYQFKYRVYNSDDDDS-------YVESQYSGPIRTDPIAEENNTGTT Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA PKEYCNRGLDDDTEYYYAFRAYNG-----MGN----VTSSTFG----------------- Spur_Spur_PTPRB9.AA QNEYCNGDLDDNTEYYYAFRAYNG-----MGN----VTSSTFG------PVKTVKDNTAG Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA NIFFSPGVLVVMVLHAALGRIVG-------------YVYPKYR-------------TSFL Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA AGAFVGILLFLILVGLLIFFLKR------------------------------------- Hsap_PTPRQ.AA ILSVTLCILSIILLGTAIFAFAR------------------------------------I Spur_Spur_PTPRB2.AA TIPIISYGVVIFFILIFLLLCCL------------------------------------- Hsap_PTPRJ.AA CGAVFGCIFGALVIVTVGGFIFW------------------------------------- Cele_dep-1.AA VAVLIVIAFVGIVGTIFLFFWNRTKKARLAAAAFKNGPSKEKESQWEALKMMMAERAADC Spur_Spur_PTPRB3.AA AAAVVSIIIITLVLLLVMLLISR------------------------------------Q Spur_Spur_PTPRB5.AA VIPAIVLAIMVVIILIIFMAMGF------------------------------------G Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA IIGISTALFSLLVVVIILSIVII------------------------------------- Dmel_Ptp10D.AA IVAITVPLTIILVLLVTLLFYKR------------------------------------- Dmel_Ptp4E.AA VAATVSAVLLVAMVLVVVYCQHR------------------------------------C Hsap_PTPRO.AA VISVLAILSTLLIGLLLVTLIIL------------------------------------- Hsap_PTPRB.AA AIEGVSAGLFLIGMLVAVVALLI------------------------------------C Aque_Aque_PTPRB-1.AA IVIAVVVVLLVIILLIAILVIVV------------------------------------- Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA IAAGVSVSLIIIIVAVVVVVVFL------------------------------------K Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA LCFAVVSIYLFVGLRLLLYFLC-------------------------------------- Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA RQKQKEGGTYSPQDAEIIDTKLKLD----------------------------------- Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA LAKLGLDATTPPPSSTTSSNSPTSTSTTMTDCGSNPHLGAPNAGGHRRTRSLRERTGVEH Spur_Spur_PTPRB3.AA CCGEARSSALYERGNGQHLPLVNAAYPSAHNQDSMHKTPLPEDAFIRMGPIPVRENA--- Spur_Spur_PTPRB5.AA CCGKPDDGMYSDDSNGYGNDYSNGNGYSNGNGNGIMKRALINDGVNTYAYQQPQIMEHSF Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA -----------------------------------------------------------R Dmel_Ptp4E.AA QL---------------------------------------------------------- Hsap_PTPRO.AA ------------RKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLW Hsap_PTPRB.AA RQKVSHGRERPSA----------------------------------------------- Aque_Aque_PTPRB-1.AA ----------------IIVLKRRKRKAYSFAASFNGKEELITAGEGKGATLSKAIQLTPT Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA RRQPKEPSPRPSLEGRENQG---------------------------------------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA --------RNKKKQQKPELRDLVFSSPGDIPAEDFADHVRKNERDSN----CGFADKYQQ Hsap_PTPRQ.AA --QLITVADLELKDERLTRLLSYRKSIKPISKKSFLQHVEELCTNNN----LKFQEEFSE Spur_Spur_PTPRB2.AA --------SSGRHGRKKVKSSPGPRKARGFHSPQQESRFNDNHNNSS----NRHPRHSKA Hsap_PTPRJ.AA -----RKKRKDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSN----CGFAEEYED Cele_dep-1.AA RLERLSSGPVHRTPLYTVVTGANTNKSRPVRIEDFADHVRLMSADSD----FRFSEEYDM Spur_Spur_PTPRB3.AA --YVSMRDDRPKAPLPATLPRSAPPLTNPVQMRKFPDHVNRMSAGNN----TGFVEEYNS Spur_Spur_PTPRB5.AA TNIPDYSTIPPNRGTTAQVHQPSTTHTRPTKKNMFAQHVAKMSARNN----AGFSDEYNN Spur_Spur_PTPRB7.AA -----------------------------------------MSARNN----DGFSDEYNS Spur_Spur_PTPRB8.AA --------------------------VRKFRLDGRGRYLPANMKDVE----LT-----RA Dmel_Ptp10D.AA RNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSD----FRFSEEFEE Dmel_Ptp4E.AA --IRRASKLARMQDELAALPEGYITPNRPVHVKDFSEHYRIMSADSD----FRFSEEFEE Hsap_PTPRO.AA TDYLLAFYINPWSKN----GLKKRKLTNPVQLDDFDAYIKDMAKDSD----YKFSLQFEE Hsap_PTPRB.AA --RLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSN----YLLSKEYEE Aque_Aque_PTPRB-1.AA DPTIVPLTENTIVNPTATASVKATPNSRKVYLRDFPSYVEDMLNDAG----FKFSEEYEK Aque_Aque_PTPRB-2.AA -----------------------------------------------------------K Spur_Spur_PTPRB6.AA ----------------------------PVK----------------------TVLKAEK Spur_Spur_PTPRB9.AA --YDGPDHEMRPTRRKTGGSMHRKSHSKPIVLNKFEGHYGRMKADSD----FRFTEEYDE Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA --HSLLMYTVTCTASMSTVWCIVLMQIASINLDFFLRFQRYIFTDEDDLNMMVFTLAMCT Spur_Spur_PTPRB4.AA ---------------------------RPVLLANIETHYDWLKADSE----HRLMEEYDD Hsap_PTPRH.AA LSLVG-HSQSQMVASA-SENNAKN--RYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPG Hsap_PTPRQ.AA LPKFL-QDLSSTDADL-PWNRAKN--RFPNIKPYNNNRVKLIADASVPGSDYINASYISG Spur_Spur_PTPRB2.AA PPLI--LSRPILSSQF-PL-------HYNEMVADKQHKFTME---------------FDG Hsap_PTPRJ.AA LKLVG-ISQPKYAAEL-AENRGKN--RYNNVLPYDISRVKL-SVQTHSTDDYINANYMPG Cele_dep-1.AA MRNVG-VGQSVAASEL-PINRPKN--RFTNIPSYDHSRVKLSNPNNIEGGDYINANYVPG Spur_Spur_PTPRB3.AA LSNVG-RDKSTDASRL-AVNATKN--RYRNILPFDETAVHLQDLEEGQTSDYINANYIQG Spur_Spur_PTPRB5.AA LPAME-KTRAVTAARQ-ARNDDKN--RYRNILPYDYTRVQL---KGVAGTDYINASYIKD Spur_Spur_PTPRB7.AA LPAME-KIRAVTVARN-ARNDDKN--RFRNILPYDYNRVQL---KGEVGNDYINASYIAD Spur_Spur_PTPRB8.AA IRKVG-RKMTTNTAVS-PANVGKN--RYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPG Dmel_Ptp10D.AA LKHVG-RDQPCTFADL-PCNRPKN--RFTNILPYDHSRFKLQPVDDDEGSDYINANYVPG Dmel_Ptp4E.AA LKHVG-RDQACSFANL-PCNRPKN--RFTNILPYDHSRFKLQPVDDDDGSDYINANYMPG Hsap_PTPRO.AA LKLIG-LDIPHFAADL-PLNRCKN--RYTNILPYDFSRVRLVSMNEEEGADYINANYIPG Hsap_PTPRB.AA LKDVG-RNQSCDIALL-PENRGKN--RYNNILPYDATRVKLSNVDDDPCSDYINASYIPG Aque_Aque_PTPRB-1.AA VSAVG-LDHSKDASLL-PENRAKN--RYTNILAYDHSRVKLESIDDEPGSDYINANYIPG Aque_Aque_PTPRB-2.AA VSAVG-LDHSKDASLL-PENRAKN--RYTNILAYDHSRVKLESIDDEPGSDYINANYIPG Spur_Spur_PTPRB6.AA IKAMMDLIMKCDQHEEKPAAQCTG-----KVILNEHSRVKLAALADDSDTDYINANYIPG Spur_Spur_PTPRB9.AA IRLVG-KDQAIVSALE-MVNRAKN--RFTNILPYEHSRVKLAALADDSDTDYINANYIPG Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA LRHISFAYEFCHFHST-PVARRPNEKQYWGILDFLLYIYYLPLFFGGPVLTY-------- Spur_Spur_PTPRB4.AA IQAVGSIVRMDQATNA-EVNKTKN--RFNKILPYEHSRVKLMALKGKSETDYINANYIPG Hsap_PTPRH.AA LWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP-LDSQPC- Hsap_PTPRQ.AA YLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWP-EDNKPVT Spur_Spur_PTPRB2.AA FNKPQEYIATQGPMSNTVHEFWRMVWEKECPAIVMLVRCIEGGKEKCDKYWP-INSDPT- Hsap_PTPRJ.AA YHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWP--SKQAQ- Cele_dep-1.AA FSSRREFIAAQGPLPTTRDHFWQMTWEQQCPAIIALTKCVEKGRDKCHQYWPDHENVPV- Spur_Spur_PTPRB3.AA LHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWP-DDDTPV- Spur_Spur_PTPRB5.AA DHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWP-AGEEPQ- Spur_Spur_PTPRB7.AA DQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWP-TGQKPH- Spur_Spur_PTPRB8.AA FTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQYWP-DDHMPV- Dmel_Ptp10D.AA HNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-NDTVPV- Dmel_Ptp4E.AA HNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-VDRVAM- Hsap_PTPRO.AA YNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPI- Hsap_PTPRB.AA NNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWP-ADQDSL- Aque_Aque_PTPRB-1.AA YRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWP--GAQPE- Aque_Aque_PTPRB-2.AA YRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWP--GAQPE- Spur_Spur_PTPRB6.AA YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR-------------- Spur_Spur_PTPRB9.AA YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWP-ADYNPV- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA DKFSRQWKHILKELFRYI--FWAMFIETVLHFL----------------YFPAFHQRPF- Spur_Spur_PTPRB4.AA FNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTKTVEGGKDKCHQYWPKKKGRSDT Hsap_PTPRH.AA THGHLRVTLVGEEVMENWTVRELLLLQVEEQKT--------------------------- Hsap_PTPRQ.AA VFGDIVITKLMEDVQIDWTIRDLKIERHGD----C------------------------- Spur_Spur_PTPRB2.AA VFGKVIVTKLAEHTHDTWAVRDFRLKVGSEE----------------------------- Hsap_PTPRJ.AA DYGDITVAMTSEIVLPEWTIRDFTVKNIQTSES--------------------------- Cele_dep-1.AA LYGDIEVTIVAEKEFDEFVIRDIRLEKSGPDGRVT------------------------- Spur_Spur_PTPRB3.AA NYGSVTVTMTHTQEMEQWTVRSFLLEKGMQ----Q------------------------- Spur_Spur_PTPRB5.AA LHGNVTVTLVGSNQTDNFIERTLLLEKEGT----E------------------------- Spur_Spur_PTPRB7.AA LHGNVTVTLVGSKQTEHFIQRTLLIGKKGT----E------------------------- Spur_Spur_PTPRB8.AA LYGDIQVTMNQTFEENDWNIKEFAVQLRDQ----R------------------------- Dmel_Ptp10D.AA FYGDIKVQILNDSHYADWVMTEFMLCRGSEQ----------------------------- Dmel_Ptp4E.AA FYGDIKVQLIIDTHYHDWSISEFMVSRNCES----------------------------- Hsap_PTPRO.AA AYGDITVEMISEEEQDDWACRHFRINYADEM----------------------------- Hsap_PTPRB.AA YYGDLILQMLSESVLPEWTIREFKICGEEQLDAH-------------------------- Aque_Aque_PTPRB-1.AA VYGEINVDMLSETEKSDWIVRKFKITKEKRS----------------------------- Aque_Aque_PTPRB-2.AA VYGEINVDMLSETEKSDWIVRKFKITKEKRS----------------------------- Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA TYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRT Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA LLNSMSL----------WAVGGLALCQ--------------------------------- Spur_Spur_PTPRB4.AA YGGSLEVSLQSELDYEHWITRTFMLQKNKM----K------------------------- Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA ------------------------------------------------------------ Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA ------------------------------------------------------------ Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA VREAIQKTASDRPIVAHCSAGAIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFS Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA -------LSVRQFHYQAWPDHGVP--SSPDTLLAFWRMLRQWLDQT-MEGGPPIVHCSAG Hsap_PTPRQ.AA -------MTVRQCNFTAWPEHGVP--ENSAPLIHFVKLVRASRAHD---TTPMIVHCSAG Spur_Spur_PTPRB2.AA -------RLIRQYHFISWPTHSTP--RVSRPTLNFVKNIREELESP-KLSGPLVVHCGAG Hsap_PTPRJ.AA -------HPLRQFHFTSWPDHGVP--DTTDLLINFRYLVRDYMKQS-PPESPILVHCSAG Cele_dep-1.AA -------RFVRHWHYMAWPDFGAP--SHPNGIIQFSRMFRHHLPHS-PHNAPTIVHCSAG Spur_Spur_PTPRB3.AA -------FETHQYAFKGWVDHDVP--NNARPMIEFIRTIDVAHDAN---LGPITVHCSAG Spur_Spur_PTPRB5.AA -------RTVTHYQYLAWTDHGVP--ESTAPLVGLLRQVKVTNQEDGAATGPIVVHCSAG Spur_Spur_PTPRB7.AA -------LTVTHYQYLAWTDHGVP--ASTAPLVALLYQVKMTSQEDGALTGPIIVHCSAG Spur_Spur_PTPRB8.AA -------RYVRHWNFLSWPDHGVP--ESSQALLAFIRRIRSTKPPS---SAPVAVHC--- Dmel_Ptp10D.AA -------RILRHFHFTTWPDFGVP--NPPQTLVRFVRAFRDRIGAE---QRPIVVHCSAG Dmel_Ptp4E.AA -------RIMRHFHFTTWPDFGVP--EPPQSLVRFVRAFRDVIGTD---MRPIIVHCSAG Hsap_PTPRO.AA -------QDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS---KGPMIIHCSAG Hsap_PTPRB.AA -------RLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRS-PGAGPTVVHCSAG Aque_Aque_PTPRB-1.AA -------RTITHYQFVSWPDHGVP--DEAGPALDFVREVHEVASSA---FGPVIVHCSAG Aque_Aque_PTPRB-2.AA -------RTITHYQFVSWPDHGVP--DEAGPALDFVREVHEVASSA---FGPVIVHCSAG Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ISQGDEIRKLTQYHFMSWPDHGVP--DKTWTMLDFVRTVREAIQKT-ASDRPIVAHCSAG Spur_Spur_PTPRB10.AA ----------------------------------------------------------AG Spur_Spur_PTPRB1.AA -------LLFFQMKYTVM--YGLP-------------RVHAMFDHI---NAPLPPVCILG Spur_Spur_PTPRB4.AA -------REVIQLQFTSWPDHGVP--EQTKPMLDFVKNVRERIRNK-CVIKPVIVHCSAG Hsap_PTPRH.AA VGRTGTLIALDVLLRQLQSE---GLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL Hsap_PTPRQ.AA VGRTGVFIALDHLTQHINDH---DFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLL Spur_Spur_PTPRB2.AA IGRTGVFIALDILLQELKAD--ERTVDVFAVVAKMRRERCSLVQSLVQYIFLHRALADFL Hsap_PTPRJ.AA VGRTGTFIAIDRLIYQIENE---NTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIV Cele_dep-1.AA VGRSGTFISIDRLLQSSSFG---DPIDVFGTVCEMRYERCQMVQNEQQYIFIHYCILQVL Spur_Spur_PTPRB3.AA IGRTGVFIALHKLIKQVETSKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLLM Spur_Spur_PTPRB5.AA VGRTGTFIAADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI Spur_Spur_PTPRB7.AA IGRTGTFIAADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQTLVRDK---------- Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA VGRSGTFITLDRILQQINTS---DYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVL Dmel_Ptp4E.AA VGRSGTFIALDRILQHIHKS---DYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL Hsap_PTPRO.AA VGRTGTFIALDRLLQHIRDH---EFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMW Hsap_PTPRB.AA VGRTGTFIALDRILQQLDSK---DSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL Aque_Aque_PTPRB-1.AA VGRTGTFIALGTLLQHIKDH---DWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC Aque_Aque_PTPRB-2.AA VGRTGTFIALGTLLQHIKDH---DWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA VGRTGTYIALDRLMQAMQEN---DYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL Spur_Spur_PTPRB10.AA VGRTGTFIVLDNILQHMEQY---DFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI Spur_Spur_PTPRB1.AA M----------YLFQDFWRY------------FDRGLHSLLVSKYGKDFM----CNKFYY Spur_Spur_PTPRB4.AA VGRTGTYIALDRLTQHMEDN---DFVDVCGVVCEMRMHRNYLVQTETQYIFIHDCLMDYF Hsap_PTPRH.AA QQSAQAPAEKEVPYEDVE------------------------------------------ Hsap_PTPRQ.AA SNKGSNQPICFVNYSALQ------------------------------------------ Spur_Spur_PTPRB2.AA QGQGHGVEVSSIERSDAG------------------------------------------ Hsap_PTPRJ.AA RSQKDSKVDLIYQNTTAM------------------------------------------ Cele_dep-1.AA QGSSPSPTSTSTGAHHNA------------------------------------------ Spur_Spur_PTPRB3.AA R----------------------------------------------------------- Spur_Spur_PTPRB5.AA EEQ--------------------------------------------------------- Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA EGKENIVGPAREMHDNEG------------------------------------------ Dmel_Ptp4E.AA EGKEHLLADSLELHANDGYEVTKIYLERQPQTKMGTLPIRASLAMAEKLDADLMTNKDED Hsap_PTPRO.AA MKKKQQFCISDVIYENVSKS---------------------------------------- Hsap_PTPRB.AA RARKLRSEQENPLFPIYE------------------------------------------ Aque_Aque_PTPRB-1.AA KSSMSKFGGGIKVLPSFP------------------------------------------ Aque_Aque_PTPRB-2.AA KSSMSKFGGGIKVLPSFP------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA RRGEEEDTGESIYVNLPS------------------------------------------ Spur_Spur_PTPRB10.AA EERGLAPVPMMSGSLP-------------------------------------------- Spur_Spur_PTPRB1.AA RT---------------------------------------------------------- Spur_Spur_PTPRB4.AA CSGVAP------------------------------------------------------ Hsap_PTPRH.AA ------------------------------------------------------------ Hsap_PTPRQ.AA ------------------------------------------------------------ Spur_Spur_PTPRB2.AA ------------------------------------------------------------ Hsap_PTPRJ.AA ------------------------------------------------------------ Cele_dep-1.AA ------------------------------------------------------------ Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA ------------------------------------------------------------ Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA ------------------------------------------------------------ Dmel_Ptp4E.AA EDQEQQQQQQLQLATEVKPKGSNDDEEDEEDDDDDDDDQQPLNNETTATLSSASCSSSTH Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------------------------ Aque_Aque_PTPRB-1.AA ------------------------------------------------------------ Aque_Aque_PTPRB-2.AA ------------------------------------------------------------ Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA ------------------------------------------------------------ Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA ---------------------------------------------NLIYENVAAIQAHKL Hsap_PTPRQ.AA --------------------------------KMDSLDAMEGDVELEWEETTM------- Spur_Spur_PTPRB2.AA --------------------------------------SIQSDEIEQMSNTSL------- Hsap_PTPRJ.AA ------------------------------------------TIYENLAPVTTFGKTNGY Cele_dep-1.AA ---------------------------------------GFVQDGQMIVESGF------- Spur_Spur_PTPRB3.AA ------------------------------------------------------------ Spur_Spur_PTPRB5.AA ------------------------------------------------------------ Spur_Spur_PTPRB7.AA ------------------------------------------------------------ Spur_Spur_PTPRB8.AA ------------------------------------------------------------ Dmel_Ptp10D.AA -----------------------------------------YEDDEGIAESGM------- Dmel_Ptp4E.AA DVHVVLQEAIEKPKQEQERICAGTQSHADTESDNTDSDDDDEDGDGKVAKDGAVADEDGW Hsap_PTPRO.AA ------------------------------------------------------------ Hsap_PTPRB.AA ------------------------------------------NVNPEYHRDPVYSRH--- Aque_Aque_PTPRB-1.AA --------------------IYSNIGPASQLSDFYGDMLSEEASYQYQKTSGNGKTYDES Aque_Aque_PTPRB-2.AA --------------------IYSNFGPASQLSDFYGDMLSEEASYQYQKTSGNGKTYDES Spur_Spur_PTPRB6.AA ------------------------------------------------------------ Spur_Spur_PTPRB9.AA -----------------------------------NGFKDPDDVNKNLLDQAV------- Spur_Spur_PTPRB10.AA ------------------------------------------------------------ Spur_Spur_PTPRB1.AA ------------------------------------------------------------ Spur_Spur_PTPRB4.AA ------------------------------------------------------------ Hsap_PTPRH.AA EV Hsap_PTPRQ.AA -- Spur_Spur_PTPRB2.AA -- Hsap_PTPRJ.AA IA Cele_dep-1.AA -- Spur_Spur_PTPRB3.AA -- Spur_Spur_PTPRB5.AA -- Spur_Spur_PTPRB7.AA -- Spur_Spur_PTPRB8.AA -- Dmel_Ptp10D.AA -- Dmel_Ptp4E.AA WY Hsap_PTPRO.AA -- Hsap_PTPRB.AA -- Aque_Aque_PTPRB-1.AA TF Aque_Aque_PTPRB-2.AA TF Spur_Spur_PTPRB6.AA -- Spur_Spur_PTPRB9.AA -- Spur_Spur_PTPRB10.AA -- Spur_Spur_PTPRB1.AA -- Spur_Spur_PTPRB4.AA --