CLUSTAL W (1.81) multiple sequence alignment

Hsap_PTPRU.AA      MARAQALVLALTFQLC---------APETETPAAGCTFEEASDPAVPCEYSQAQY-DDFQ
Hsap_PTPRK.AA      MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDD---GPGACDYHQDLY-DDFE
Hsap_PTPRM.AA      -MRGLGTCLATLAGLLL--------TAAGETFSGGCLFDE---PYSTCGYSQSEG-DDFN
Hsap_PTPRT.AA      MASLAALALSLLLRLQL----PPLPGARAQSAAGGCSFDE---HYSNCGYSVALGTNGFT
                        .  *.    *           .  :  :.** *::       * *      :.* 

Hsap_PTPRU.AA      WEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRD
Hsap_PTPRK.AA      WVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQK
Hsap_PTPRM.AA      WEQVNTLTKPTSDPWMPSGSFMLVNASGRPEGQRAHLLLPQLKENDTHCIDFHYFVSSKS
Hsap_PTPRT.AA      WEQINTWEKPMLDQAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRD
                   * ::           :* **:::*::* .  *:.*.: :  :.******::* * . *..

Hsap_PTPRU.AA      GHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDR
Hsap_PTPRK.AA      GLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGR
Hsap_PTPRM.AA      NSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAELAISTFWPNFYQVIFE-VITSGH
Hsap_PTPRT.AA      RSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGH
                      ** *.: *.** ** ...:**::*     * .****:*****: ***:**     ..

Hsap_PTPRU.AA      RGYMGLDDILLLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGA
Hsap_PTPRK.AA      SGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGE
Hsap_PTPRM.AA      QGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVR
Hsap_PTPRT.AA      PGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGR
                    **:.:*:: :*.:** .:*** *: :****.** *:*** * *.    :.: **  .  

Hsap_PTPRU.AA      LVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIA
Hsap_PTPRK.AA      DIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIA
Hsap_PTPRM.AA      DAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIA
Hsap_PTPRT.AA      DTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIA
                     .    .  . *** *:. :  .:. . . ***: .:  * *:**:*:*:*.*** ***

Hsap_PTPRU.AA      PPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPD
Hsap_PTPRK.AA      PPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPD
Hsap_PTPRM.AA      PPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPD
Hsap_PTPRT.AA      PPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPD
                   **:*  .*.*** *: *:*** *****: .*:**  : *.* : : *.  .**: *****

Hsap_PTPRU.AA      TEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFAEIQARQLTLQWEPLGYN
Hsap_PTPRK.AA      TEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYN
Hsap_PTPRM.AA      TEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYN
Hsap_PTPRT.AA      VEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYA
                   .**** *******:**** ***.* :*****:*:. *. : ..::.:*.::: **.:** 

Hsap_PTPRU.AA      VTRCHTYTVSLCYHYTLGSSHNQTIRECV-KTEQGVSRYTIKNLLPYRNVHVRLVLTNPE
Hsap_PTPRK.AA      ITRCHTFNVTICYHYFRG--HNESKADCL-DMDPKAPQHVVNHLPPYTNVSLKMILTNPE
Hsap_PTPRM.AA      VTRCHSYNLTVHYCYQVG-GQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPE
Hsap_PTPRT.AA      VTRCHSYNLTVQYQYVFN--QQQYEAE---EVIQTSSHYTLRGLRPFMTIRLRLLLSNPE
                   :****::.::: * *  .  :::   :   .     ..:.:  * *: .: :.::* ***

Hsap_PTPRU.AA      GRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIES
Hsap_PTPRK.AA      GRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRS
Hsap_PTPRM.AA      GRKESQELIVQTDEDLPGAVPTESIQGSTFEEKIFLQWREPTQTYGVITLYEITYKAVSS
Hsap_PTPRT.AA      GRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGS
                   ** *.:*  .**:**:*. :. :*:   .:*: *:::*  * :. *:** ***.*.:: *

Hsap_PTPRU.AA      SDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTGKGFGQAALTEITTNISA
Hsap_PTPRK.AA      FDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISA
Hsap_PTPRM.AA      FDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISA
Hsap_PTPRT.AA      LDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISA
                    **   :..    : :* *.*:.:*  *:***** * :.* * **** ..   .:*:***

Hsap_PTPRU.AA      PSF-DYADMPSPLGESENTITVLLRPAQGRGAPISVYQVIVEEERARRLRREPGGQDCFP
Hsap_PTPRK.AA      PTLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAMECYQ
Hsap_PTPRM.AA      PSMPAY-ELETPLNQTDNTVTVMLKPAHSRGAPVSVYQIVVEEERPRRTKKTTEILKCYP
Hsap_PTPRT.AA      PSMPEY-DTDTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFS
                   *::  *    :.*.:: .*:**:*.**:..***:*.**::*:* . .. .. .   .*: 

Hsap_PTPRU.AA      VPLTFEAALARGLVHYFGAELAASSLPEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQA
Hsap_PTPRK.AA      VPVTYQNAMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQA
Hsap_PTPRM.AA      VPIHFQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPYKSYRIYFQA
Hsap_PTPRT.AA      VPVSYRNASSLDSLHYFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQA
                   **: :  *   .  :**.**: . .*  . ***:***.**.*:**.** * *.* *****

Hsap_PTPRU.AA      ASHLKGETRLNCIRIARK-------------------AACKESKRP-LEVSQRSEEMGLI
Hsap_PTPRK.AA      MSSVEKETKTQCVRIATK-------------------AAATEEPEVIPDPAKQTDRVVKI
Hsap_PTPRM.AA      ASRANGETKIDCVQVATK-------------------GAAT--PKPVPEPEKQTDHTVKI
Hsap_PTPRT.AA      LSKANGETKINCVRLATKAPMGSAQVTPGTPLCLLTTGASTQNSNT-VEPEKQVDNTVKM
                    *  : **. :*:.:* *                   .*..       :  :. :    :

Hsap_PTPRU.AA      LGICAGGLAVLILLLGAIIVIIRKGRDHYAYSYYPKPVNMTKATV-NYRQEKTHMMSAVD
Hsap_PTPRK.AA      AGISAGILVFILLLLV-VILIVKKS----------KLAKKRKDAMGNTRQEMTHMVNAMD
Hsap_PTPRM.AA      AGVIAGILLFVIIFLG-VVLVMKKR----------KLAKKRKETMSSTRQEMTVMVNSMD
Hsap_PTPRT.AA      AGVIAGLLMFIIILLG-VMLTIKRRRNAYSYSYYLKLAKKQKETQSGAQREMGPVASA-D
                    *: ** * .::::*  ::: :..           * .:  * :  . ..*   : .: *

Hsap_PTPRU.AA      RSFTDQSTLQEDERLGLSFMDTHGYSTRG-------------------------------
Hsap_PTPRK.AA      RSYADQSTLHAEDPLSITFMDQHNFSPR--------------------------------
Hsap_PTPRM.AA      KSYAEQGTNCDE---AFSFMDTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDPFVPTA
Hsap_PTPRT.AA      KPTTKLSASRNDEGFSSSSQDVNGFT----------------------------------
                   .. :. .:   :   . :  * :. .                                  

Hsap_PTPRU.AA      ------DQRSGGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAE
Hsap_PTPRK.AA      ------YENHSATAESSRLLDV-PRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSD
Hsap_PTPRM.AA      ILVPINDETHTMASDTSSLVQSHTYKKREPADVPYQTGQLHPAIRVADLLQHITQMKCAE
Hsap_PTPRT.AA      ------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQ
                                ::.:  :   .         .*  .*::**:*********. ** .:

Hsap_PTPRU.AA      GYGFKQEYESFFEG----WDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINA
Hsap_PTPRK.AA      SYGFKEEYESFFEGQSASWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINA
Hsap_PTPRM.AA      GYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYING
Hsap_PTPRT.AA      GYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINA
                   .****:***:: **    ** :*:.::   .*   : :**. ** *  : .*. :****.

Hsap_PTPRU.AA      NYI------DGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSR
Hsap_PTPRK.AA      NYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYK
Hsap_PTPRM.AA      NYI------DGYHRPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCK
Hsap_PTPRT.AA      NYI------DGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVR
                   ***      ***:*. *:******  * : *****:*:*: :.*:*:*:********* .

Hsap_PTPRU.AA      YWPEDSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHA
Hsap_PTPRK.AA      YWPDDTEVYGDFKVTCVEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHA
Hsap_PTPRM.AA      YWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHA
Hsap_PTPRT.AA      YWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYA
                   ***:*:: * *:*:  :: * *****:***:::..*    .*:. ****.**:**** :*

Hsap_PTPRU.AA      TGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTL
Hsap_PTPRK.AA      TGLLSFIRRVKLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKAL
Hsap_PTPRM.AA      TGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVREL
Hsap_PTPRT.AA      TGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVREL
                   ****.*:*.**  .**.***:*:*****:*****:*.:* ****** ******:***. *

Hsap_PTPRU.AA      CSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEF
Hsap_PTPRK.AA      RSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEF
Hsap_PTPRM.AA      RSRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEF
Hsap_PTPRT.AA      RAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEF
                    :.*:*::******:*:***********:*::*..:..: * :: .:*.*:***::.:**

Hsap_PTPRU.AA      QTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDS
Hsap_PTPRK.AA      QTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALMDS
Hsap_PTPRM.AA      RTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDS
Hsap_PTPRT.AA      QTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDS
                   .*** *** :  *:***. ****.:*** **:** ********: **:*.******* **

Hsap_PTPRU.AA      YTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQY
Hsap_PTPRK.AA      YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDLSQG---CPQYWPEEGMLRY
Hsap_PTPRM.AA      YKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQL---CPQYWPENGVHRH
Hsap_PTPRT.AA      HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQF---CMQYWPEKTSGCY
                   : ..:**:** :** .*. ****** ** *:*:****::: ::    * *****     :

Hsap_PTPRU.AA      GLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAYRDTPDSKKAFLHL
Hsap_PTPRK.AA      GPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKL
Hsap_PTPRM.AA      GPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKL
Hsap_PTPRT.AA      GPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKV
                   * ::** :*   : *:: *:**: * :* *:*: :*.::*:: *. :*:.* **.::*::

Hsap_PTPRU.AA      LAEVDKWQAE--SGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNY
Hsap_PTPRK.AA      ILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNS
Hsap_PTPRM.AA      IRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNN
Hsap_PTPRT.AA      VRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNN
                   :  ::*** :    :***::********** ***   * **:. :. :***. .***** 

Hsap_PTPRU.AA      KPNMVETMDQYHFCYDVALEYLEGLESR
Hsap_PTPRK.AA      KPNMVEAPEQYRFCYDVALEYLESS---
Hsap_PTPRM.AA      KPNMVDLLDQYKFCYEVALEYLNSG---
Hsap_PTPRT.AA      KSNMVETLEQYKFVYEVALEYLSSF---
                   *.***:  :**.* *:******..