CTD Phosphorylation - Revision history

Mark: /* Phosphatases */

2016-05-15T00:12:18Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-15T00:12:01Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-15T00:10:08Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-15T00:09:20Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-15T00:09:01Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-15T00:03:56Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-14T23:06:30Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-14T23:05:04Z

‎Phosphatases

Mark: /* Phosphatases */

2016-05-14T23:03:18Z

‎Phosphatases

Mark: /* Kinases */

2016-05-14T23:01:57Z

‎Kinases

@@ Line 17: / Line 17: @@
 ! scope="col" | Note
 |-
-! scope="row" | [[FCP1]]
+! scope="row" | FCP1
 | FCP1 || HAD || FCP || [[Phosphatase_Subfamily_FCP1|FCP1]] || pSer2, pThr4 <cite>hsin2014</cite> || To Recycling || From yeast to human ||
 |-

@@ Line 24: / Line 24: @@
 |-
 ! scope="row" | SSU72
-| SSU72 || CC2|| SSU72 || [[Phosphatase_Subfamily_SSU72|SSU72]] || pSer5 || To cleavage, polyA and termination || From yeast to human ||  1) Its function toward pSer5 has been verified in yeast, but not mammals. 2) Unlike other phosphatases, it has a fold similar to LMWPTP rather than HAD.
+| SSU72 || CC2|| [[Phosphatase_Family_SSU72|SSU72]] || SSU72 || pSer5 || To cleavage, polyA and termination || From yeast to human ||  1) Its function toward pSer5 has been verified in yeast, but not mammals. 2) Unlike other phosphatases, it has a fold similar to LMWPTP rather than HAD.
 |-
 ! scope="row" | CTDSPL2

@@ Line 27: / Line 27: @@
 |-
 ! scope="row" | CTDSPL2
-| N/A || HAD || FCP || [[Phosphatase_Subfamily_CTDSPL2|CTDSPL2]] || ? || ? || From Monosiga to human but lost in fly || 1) In vitro activity toward CTD. 2) HSPC129 was divergent from SCP family.
+| N/A || HAD || FCP || [[Phosphatase_Subfamily_CTDSPL2|CTDSPL2]] || ? || ? || From Monosiga to human but lost in fly || 1) In vitro activity toward CTD.
 |-
 ! scope="row" | UBLCP1

@@ Line 21: / Line 21: @@
 |-
 ! scope="row" | SCP1, SCP2, SCP3
-| SCP || HAD || FCP || || [[Phosphatase_Subfamily_SCP|SCP]] || pSer5 || To cleavage, polyA and termination || From yeast to human || The function toward pSer5 of one of its member, SCP1, has been verified in mammals, but not in yeast, yet.
+| SCP || HAD || FCP || [[Phosphatase_Subfamily_SCP|SCP]] || pSer5 || To cleavage, polyA and termination || From yeast to human || The function toward pSer5 of one of its member, SCP1, has been verified in mammals, but not in yeast, yet.
 |-
 ! scope="row" | SSU72

@@ Line 11: / Line 11: @@
 ! scope="col" | Group
 ! scope="col" | Family
 ! scope="col" | Substrate
 ! scope="col" | Stage
@@ Line 17: / Line 18: @@
 |-
 ! scope="row" | [[FCP1]]
-| FCP1 || HAD || FCP || pSer2, pThr4 <cite>hsin2014</cite> || To Recycling || From yeast to human ||
+| FCP1 || HAD || FCP || [[Phosphatase_Subfamily_FCP1|FCP1]] || pSer2, pThr4 <cite>hsin2014</cite> || To Recycling || From yeast to human ||
 |-
-! scope="row" | [[SCP]]
+! scope="row" | SCP1, SCP2, SCP3
-| SCP || HAD || FCP || pSer5 || To cleavage, polyA and termination || From yeast to human || The function toward pSer5 of one of its member, SCP1, has been verified in mammals, but not in yeast, yet.
+| SCP || HAD || FCP || || [[Phosphatase_Subfamily_SCP|SCP]] || pSer5 || To cleavage, polyA and termination || From yeast to human || The function toward pSer5 of one of its member, SCP1, has been verified in mammals, but not in yeast, yet.
 |-
-! scope="row" | [[SSU72]]
+! scope="row" | SSU72
-| SSU72 || CC2|| SSU72 || pSer5 || To cleavage, polyA and termination || From yeast to human ||  1) Its function toward pSer5 has been verified in yeast, but not mammals. 2) Unlike other phosphatases, it has a fold similar to LMWPTP rather than HAD.
+| SSU72 || CC2|| SSU72 || [[Phosphatase_Subfamily_SSU72|SSU72]] || pSer5 || To cleavage, polyA and termination || From yeast to human ||  1) Its function toward pSer5 has been verified in yeast, but not mammals. 2) Unlike other phosphatases, it has a fold similar to LMWPTP rather than HAD.
 |-
-! scope="row" | [[HSPC129]]
+! scope="row" | CTDSPL2
-| N/A || HAD || FCP || ? || ? || From Monosiga to human but lost in fly || 1) In vitro activity toward CTD. 2) HSPC129 was divergent from SCP family.
+| N/A || HAD || FCP || [[Phosphatase_Subfamily_CTDSPL2|CTDSPL2]] || ? || ? || From Monosiga to human but lost in fly || 1) In vitro activity toward CTD. 2) HSPC129 was divergent from SCP family.
 |-
-! scope="row" | [[UBLCP1]]
+! scope="row" | UBLCP1
-| N/A || HAD || SCP || ? || ? || From anemone to human but lost in nematode || 1) In vitro activity toward CTD.
+| N/A || HAD || FCP || [[Phosphatase_Subfamily_UBLCP1|UBLCP1]] || ? || ? || From anemone to human but lost in nematode || 1) In vitro activity toward CTD.
 |-
 ! scope="row" | RPAP2
-| RTR1, RTR2 || RTR1 || RTR1 || pSer5, pTyr1 ||  || RTR1 is found in most of eukaryotes. It is absent from Monosiga and sponge genome ||
+| RTR1, RTR2 || RTR1 || RTR1 || [[Phosphatase_Subfamily_RTR1|RTR1]] || pSer5, pTyr1 || ? || RTR1 is found in most of eukaryotes. It is absent from Monosiga and sponge genome ||
 |-
 ! scope="row" | ?
-| N/A || ? || ? || pSer7 || ? || ? || Observed phosphorylated pSer7, but the phosphatase and kinase are unknown.
+| N/A || ? || ? || ? || pSer7 || ? || ? || Observed phosphorylated pSer7, but the phosphatase and kinase are unknown.
 |}

@@ Line 31: / Line 31: @@
 | N/A || HAD || SCP || ? || ? || From anemone to human but lost in nematode || 1) In vitro activity toward CTD.
 |-
-! scope="row" | [[Phosphatase_Subfamily_RTR1|RTR1]]
+! scope="row" | RPAP2
-| RTR1, RTR2 || RTR1 || RTR1 || RTR1 || pSer5 || From anemone to human but lost in nematode || 1) In vitro activity toward CTD.
+| RTR1, RTR2 || RTR1 || RTR1 || RTR1 || pSer5, pTyr1 || RTR1 is found in most of eukaryotes. It is absent from Monosiga and sponge genome ||
 |-
 ! scope="row" | ?

@@ Line 65: / Line 65: @@
 ! scope="row" | ERK1/2
 | FUS3, KSS1, SLT2, SMK1, YKL161C ||  CMGC || MAPK || ERK1 || Ser5 || In the pool of pol II? || From Monosiga to human || Many yeast proteins in this subfamily of extracellular signal-related kinase 1/2 (ERK1 in KinBase).
 |}