Difference between revisions of "Main Page"

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(Protein Phosphatase Classification and Evolution)
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Welcome to Phosphatase Wiki, a resource for of phosphatases and phosphatase signaling. This is a pilot project for sharing and publication of discoveries that do not fit into traditional publications or haven't yet been polished for publication. Initial content is mostly from the Manning lab at Salk (moved to Genentech in 2012), but we welcome anyone who would like to contribute. Like other wiki's, just go to the login page to request an account.
 
Welcome to Phosphatase Wiki, a resource for of phosphatases and phosphatase signaling. This is a pilot project for sharing and publication of discoveries that do not fit into traditional publications or haven't yet been polished for publication. Initial content is mostly from the Manning lab at Salk (moved to Genentech in 2012), but we welcome anyone who would like to contribute. Like other wiki's, just go to the login page to request an account.
  
===[[Introduction to Phosphatases]]===
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== [[Introduction to Phosphatases]] ==
 
* [[Phosphatases_and_Diseases|Phosphatases and diseases]]  
 
* [[Phosphatases_and_Diseases|Phosphatases and diseases]]  
 
* [[Drug_Targeting_Phosphatases|Phosphatases as drug targets]]
 
* [[Drug_Targeting_Phosphatases|Phosphatases as drug targets]]
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* [[regulatory_subunits|Regulatory subunits]]: some phosphatases, particularly PPPs, consist of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
 
* [[regulatory_subunits|Regulatory subunits]]: some phosphatases, particularly PPPs, consist of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
  
=== [[phosphatase classification|Protein Phosphatase Classification and Evolution]]===
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== [[phosphatase classification|Protein Phosphatase Classification and Evolution]] ==
 
===== [[Phosphatase_classification#Classification_Chart_of_Protein_Phosphatases|Classification chart]] =====
 
===== [[Phosphatase_classification#Classification_Chart_of_Protein_Phosphatases|Classification chart]] =====
 
===== [[Pseudophosphatases|Catalytically inactive phosphatases (pseudophosphatases)]] =====
 
===== [[Pseudophosphatases|Catalytically inactive phosphatases (pseudophosphatases)]] =====

Revision as of 19:46, 9 September 2015

Welcome to Phosphatase Wiki, a resource for of phosphatases and phosphatase signaling. This is a pilot project for sharing and publication of discoveries that do not fit into traditional publications or haven't yet been polished for publication. Initial content is mostly from the Manning lab at Salk (moved to Genentech in 2012), but we welcome anyone who would like to contribute. Like other wiki's, just go to the login page to request an account.

Introduction to Phosphatases

Protein Phosphatase Classification and Evolution

Classification chart
Catalytically inactive phosphatases (pseudophosphatases)
Phosphorylation of RNA polymerase II C-terminal domain

The C-terminal domain of RNA polymerase II's largest subunit undergoes dynamic phosphorylation during transcription, and the different phosphorylation patterns that predominate at each stage of transcription recruit the appropriate set of mRNA-processing and histone-modifying factors. This complex phosphorylation patterns are regulated by quite a few phosphatases and kinases.

Glossary

Technical notes