Difference between revisions of "Phosphatase Fold CC1"
From PhosphataseWiki
| (4 intermediate revisions by one user not shown) | |||
| Line 3: | Line 3: | ||
Fold CC1 has a single superfamily [[Phosphatase_Superfamily_CC1|CC1]]. | Fold CC1 has a single superfamily [[Phosphatase_Superfamily_CC1|CC1]]. | ||
| − | === | + | === Structure === |
We carried out structural alignment analysis of the crystal structures of five phosphatases of different families (Paladin and OCA has no structure), including human DUSP3 (DSP), PTEN (PTEN), PTPN1 (PTP), MTMR2 (myotubularin) and yeast Sac1p (Sac) (family names in parentheses). We compared the secondary structures and identified the common and family-specific secondary structures (SSs). | We carried out structural alignment analysis of the crystal structures of five phosphatases of different families (Paladin and OCA has no structure), including human DUSP3 (DSP), PTEN (PTEN), PTPN1 (PTP), MTMR2 (myotubularin) and yeast Sac1p (Sac) (family names in parentheses). We compared the secondary structures and identified the common and family-specific secondary structures (SSs). | ||
| − | All | + | All the five phosphatases share the same secondary structure (SS) combination of E2, E3, H2, E4, E11, H3, E12, H4, H5, H6 (E denotes beta strand, H denotes helix, SS numbered by PTP <cite> Andersen01</cite>). |
| − | + | ||
| − | + | ||
| − | + | ||
| − | + | ||
| − | + | ||
| − | + | ||
| − | + | === References === | |
| + | <biblio> | ||
| + | #Andersen01 pmid=11585896 | ||
| + | </biblio> | ||
Revision as of 19:57, 11 November 2015
Phosphatase Classification: Fold CC1
Fold CC1 has a single superfamily CC1.
Structure
We carried out structural alignment analysis of the crystal structures of five phosphatases of different families (Paladin and OCA has no structure), including human DUSP3 (DSP), PTEN (PTEN), PTPN1 (PTP), MTMR2 (myotubularin) and yeast Sac1p (Sac) (family names in parentheses). We compared the secondary structures and identified the common and family-specific secondary structures (SSs).
All the five phosphatases share the same secondary structure (SS) combination of E2, E3, H2, E4, E11, H3, E12, H4, H5, H6 (E denotes beta strand, H denotes helix, SS numbered by PTP [1]).
