Difference between revisions of "Phosphatase Superfamily CC1"
From PhosphataseWiki
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- [[Phosphatase_Family_PTP|Classic PTP]] (Protein Tyrosine Phosphatase; generally tyrosine specific) | - [[Phosphatase_Family_PTP|Classic PTP]] (Protein Tyrosine Phosphatase; generally tyrosine specific) | ||
| − | - [[ | + | - [[Phosphatase_Family_DSP|DSP]] (Dual Specificity Phosphatases; tyr/ser/thr specific) |
| + | |||
| + | - [[Phosphatase_Family_PTEN|PTEN]] Lipid phosphatases closely related to DSPs. | ||
- [[Phosphatase_Family_Myotubularin|Myotubularin]] (lipid specific). | - [[Phosphatase_Family_Myotubularin|Myotubularin]] (lipid specific). | ||
Revision as of 01:29, 28 December 2014
Phosphatase classification: Superfamily CC1
CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human:
- Classic PTP (Protein Tyrosine Phosphatase; generally tyrosine specific)
- DSP (Dual Specificity Phosphatases; tyr/ser/thr specific)
- PTEN Lipid phosphatases closely related to DSPs.
- Myotubularin (lipid specific).
Fungi, plants and many protists also have the OCA family.
It shares a Cys-based catalytic motif, CX5R with another two superfamilies CC2 and CC3, but it has distinct structure from them.
