Phosphatase Superfamily CC1
From PhosphataseWiki
Phosphatase classification: Superfamily CC1
Phosphatase superfamily Cys-based I is the biggest phosphatase superfamily. It consists of three families in human: Classic PTP (Protein Tyrosine Phosphatase; generally tyrosine specific), DSP and PTEN (Dual Specificity Phosphatases; tyr/ser/thr specific) and Myotubularin (lipid specific). In fungi, plants and many protists, another family OCA is also found.
It shares the common Cys-based catalytic motif, CX5R with another two superfamilies Cys-based I and Cys-based III, but it has distinct structure from them.
