PTC5
Species: S.cerevisiae
Alias: Ser133 of Pda1, PTC5, which is the E1alpha subunit of pyruvate dehydrogenase complex.
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPM
Family: PPM
Subfamily: PDP
Protein domain

Protein domains of PTC5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PTC5.AA PP2Cc 143-541 21 5e-81 276.41 SMART 1-338 (338) Show / Hide
Range on Protein: 143-541
Range on HMM: 1-338/338
Sequence Identity: 21% (93 aa)

HFVNRGTGIFRYDV---AQLPSNHPIEDDHVEQIITIPIESEDGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPN---
|. ... ...|| .   .. . .||.||.||  .                  |||.||||||. ... ..| |....| .| .. |... ...   .   
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP------------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKEND-E-MQDE

-------------QLIDSAISKGFLKLDNDLVIESFRKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLDNEGNW------T
             ...  |. |.||..|...                          ..|...|    .  | || .||||| .|  .|. ||      |
PEMWWRMWHDKWFEDWEDALRKAFLRMDEEI--------------------------CTAVVALIRGNK--LYVANVGDSRAVLCRNGND-NWWGIRHYT

VKSLSTDQTGDNLDEVRRIRKEHPGE----PNVIRNG-----RILGS---LQPSRAFGDYRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEP
.. |..|.. || ||.|||.......     ....|.     |..|.   |..||||||. ||  . | . ...  .. ..|....|| ....|||.|||
AHQLTEDHKPDNEDERRRIEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KED-E-KIE--WN-RWYQMFDPRLPFKEPYVIAEP

VITSAKI------GENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIDVSEDKEAQRPAFRYKDNNSSSPSGSNPEYLIEDKN
 .|. ..       .  .|.....|||.. ..|.|. ..| .. .|.... ||| .. ... . . . .                  .  ...   ... 
DVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHK-PVKNQAQENA-H-M-M-R------------------H--RQKKHNDPME

VATHLIRNALSAGGRKEYVSALVSIPSPMSRRYRDDLTVTVA
.|..|.. |.                       .|. || | 
AAKRLCDCAI-----------------------CDNMTVIVV

Phosphatase PTC5.AA Subfamily.PDP.PD 233-540 46 1.7e-112 366.6 In-house 121-408 (409) Show / Hide
Range on Protein: 233-540
Range on HMM: 121-408/409
Sequence Identity: 46% (148 aa)

SDPNQLIDSAISKGFLKLDNDLVIESFRKLfqdpNNTNIANTL--PAISGSCALLSLYNSTNsiLKVAVTGDSRALICGLDNEGNWTVKSLSTDQTGDNL
..... ...|..|.||.||.|...|...||    .........  .|.||.||||.|...|.  |.||.|||.||...  ..||.|....||.|||.|| 
eakelkveealkkaFlrlDkdislealkkl----eekvleeavlkvalsGacallaliegte--lhvAntGDcravlgvqeeegsweavkLskdqtadne

DEVRRIRKEHPGEPN--VIRNGRILGSLQPSRAFGDYRYKI-KEVDGKPLSDLPEVaklyFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLF
.||.||.||||||..  ||||||.||.|.|.|||||.|||. ||.. | |..|.||    ...||.|.|||||.||||..||.|..||.||.|...|||.
eEveRikkeHPgeesktvirngRlLgeLaPlRAFGdvryKwskelqkkvlekllev----kvvepkdyktPPYltaePevtshklrendkFLvlatDGLw

ELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIdvsedkeaqrpafrYKDNNSSSPSGsnpEYLIEDKNVATHLIRNALSA--GGRKEYVSALVSIP
.||.|||..|||.....|..| |.|.||| ||.|..              .|.|.....|.   |. .||||.||||||.||     |.||.||||.|||
dllsneevvslVgehlakkknkakvaaepaklkkga--------------vkenlkerksk---ekkeedknaAthLirhalggneagdkekvsallsiP

SPMSRRYRDDLTVTV
....|.||||.||||
eelaRmyRDDitvtV

Phosphatase PTC5.AA PP2C 181-466 22 2.1e-66 231.72 Pfam 1-284 (284) Show / Hide
Range on Protein: 181-466
Range on HMM: 1-284/284
Sequence Identity: 22% (68 aa)

EDGKSIEKDLYFFGIFDGHGGPFTSEK--LSKDLVRYVAYQLGQVYDQNKTVFHSDPN----QLIDSAISKGFLK--LDNDLVIESFRKLFQDPNNTN--
 |. . ... .     |.|. .. ...   .|| . ..|.. |  ..|. .....  .    . .....|   ..  .... ...||.....| .  .  
WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAP

--IAN--T-LPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLDNEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPNVIRNGRILGS-LQPSRAFGD
  ..|  . .. .||..|.. ... ...|| ||  |||||..|  .| .|| |. |..| . .| || ||||... .  .. ...|. |. |. ||||||
WHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNW-VHQLTYDHKPSNEDERRRIRQAGGWVMWW-GFWRVNGVWLAVSRAFGD

YRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEPVIT-SAKIGEN-TKFMVMGSDGLFELLTNEEIASLVIRWMDKN---MNLAPVKAEPGKL
. || ....                     |.....||||| || ..|| .  ..|.....|||.. ....|. ..| ......   | ..   .. .. 
FHYKPNHTC---------------------FPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIA

PKVIDVS
. . |  
YGSEDNI

Phosphatase PTC5.AA Group.PPM.PD 151-547 22 7.3e-59 189.4 In-house 37-325 (459) Show / Hide
Range on Protein: 151-547
Range on HMM: 37-325/459
Sequence Identity: 22% (92 aa)

IF--RYDVAQlPSNHPIEDDHV--EQIITIPiesedgksiekdlYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPN------QLID
.   ..  |  .... || ||  |.. . .              |||.||||||.. .|  .|.|..... ||... |. .   . . .      ....|
glrygvasmq-gwrkemEDrhvivenfdnnd-------------sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvk

SAISKGFLKLDNDLVIESFRKLfqdpnntnianTLPAISGSCALLSLYnSTNsILKVAVTGDSRALICgldNEGnwTVKSLSTDQTGDNLDEVRRIRKEH
. ..||.||.||  |. .|            .... ||..|.  |  . .  | || .|||||..|    .|   .. ||.| . .| .| .||.| . .
kalrsafleldedlseeaneke-----------epgkdsGtTAvvali-ngk-klyvANaGDSravLc---rng--kavplskdHkpenpeEreRIekag

-PgepnVIRNGRILGSLQPSRAFGDYRYKIkevdgkplsdlpevaklyfrreprdfkTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLV
    |  .||..|.|..|||.||...|                            . ..|.||| ... |. |. .|.|..||||.. |.|||....| .
Gs----veidgRvnGilavsRalGdhdlkk---------------------------eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefv

IRWMDKnmnlapvkaepgklpkvidvsedkeaqrpafrykdnnssspsgSNPEYLIEDKNVATHLIRNALSAGgrkeyvsalvsiPSpMSRRYRDDLTVT
 ..|                                            ..|.  . ...|..|...||..|            ..... ..|. ||.| .
retlek-------------------------------------------kkkelkkdleeiaerlvdealakg------------st-gdgtscDNiTvi

VAFFGDSG
. |.    
vvtlndam

Phosphatase PTC5.AA Family.PPM.PD 155-546 25 9.3e-54 172.5 In-house 20-289 (495) Show / Hide
Range on Protein: 155-546
Range on HMM: 20-289/495
Sequence Identity: 25% (96 aa)

DVAQlPSNHPIEDDH--VEQIITIPiesedgksiekDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPNQLIDSAISKGFLKLDN
.  |  .....|| |  ||.. . .           |...||.|||||| . .|  .|.|..... || .. |....  ... .. ...|. |.||.||.
asmq-gwrsemeDahvvvenlenne-----------dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkaflelde

DLVIESFRKLfqdpnntniantLPAISGSCALLSLYNSTNsiLKVAVTGDSRALICgldNEGnwTVKSLSTDQTGDNLDEVRRIRKEHpGEPNViRNGRI
.|  |  .|             ..  ||..|.  | ....  | || .|||||..|   ..|   .. ||.| . .| .| .||.| . |..  |.||. 
elseelneks------------agkdsGtTAvvvlirgkk--lyvAnaGDsravLc---rng--kavelskdHkpenpeEreRIekag-Gkvvi-rdgrv

LGSLQPSRAFGDYRYKIkevdgkplsdlpevaklyfrreprdfK--TppYVTAEPVITSAKIG-ENTKFMVMGSDGLFELLTNEEIASLVIRWMdknmnl
|.|..|||.||...|                           .     .|.||| ||| |.  |...|.|. ||||.. |.|||...|| . .       
nGvlavsRalGdfdlkk--------------------------eeqa--ivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretl------

apvkaepgklpkvidvsedkeaqrpafrykdnnssspsgsnPEYLIEDKNVATHLIRNALSAGGRkeyvsalvsipspmsrryrDDLTVTVAFFGDS
                                         |.  . ...|..|...||..| ||. ||.| .. ..                    
-----------------------------------------eekeedleeiaeeLvdealakgsr-------------------DNiTvlvvalyen

Phosphatase PTC5.AA Subfamily.PPM1G2.PD 187-451 26 8.9e-30 93.6 In-house 40-246 (275) Show / Hide
Range on Protein: 187-451
Range on HMM: 40-246/275
Sequence Identity: 26% (69 aa)

EKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYqlgqvydqnKTVFHsdpNQLIDSAISKGFLKLDNDLVIEsfrklfqdpnnTNIANtlpAISGSCALLS
.|.| .|..||||||   ..  .|.|....|.         |. |.   .. .. .. ..||..|..|. .           ......|| |.  | . .
dkslalfavfDGhGGakvakyagkklikkiak---------kksfk---egaleqilkdafletDeellkd-----------eklkd---esaGstavvv

LYNSTNsiLKVAVTGDSRALICgldNEGNwtVKSLSTDQTGDNLDEVRRIRKEHpGepnVIRNGRILGSLQPSRAFGDYRYKIKEVdgkplsdlpevakl
.  | || .|||||...   ..||  ||.|| |   .. .| .|| .   |   ..  .|. |.|  |||.||..| ..                     
likeek--lyvanaGDsravls---skgn--vkalsfDhkPqeesekkriiaag-G---fvelnrvngnLalsralgDfefkknvk--------------

yfrreprdfKTP--PYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAP
   |.|    |||.| ..  |. |.. |.|.  ||....|||.|.  || . . ....|        
---------kkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgaklde

Phosphatase PTC5.AA Subfamily.PPM1A.PD 185-450 27 7.1e-26 80.9 In-house 36-252 (309) Show / Hide
Range on Protein: 185-450
Range on HMM: 36-252/309
Sequence Identity: 27% (71 aa)

SIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVydqnkTVFHSDPNQLIDSAISKGFLKLDNDLviesfRKLFQDPNNTNIantlpaiSGSCAL
|  ||  ||..||||.|   |.  .|.|.. .  .         .. ...... . .|..||||.||...     |||..  ....||| |   | .  .
sklkdwsffavfDGHaGskvskycakhlleaileeeefk-----askeksskekvkealrkgfLelDeki-----rklvelskgedk-------sGsTav

LSLYNstNSILKVAVTGDSRALICGldnEGnwTVKSLSTDQTGDNLDEVRRIRKEHpGepnVIRNGRILGSLQPSRAFGDYRYKIKEvdgkplsDLPEVA
  | .|  |||||...    .|  .|.  ..|  . . .|..||..   |    . ..|. |||  |||.||||| |.       ....  .|       
vvlvs--pkklylancGDsRavlsr---ng--kvvfateDHkpsdpkEkeRienAg-G---svmikRvnGsLAvsRalGDydykekp-------ekkate

KLyfrreprdfktppyVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLA
       |..|| .|. .. |. .|.|. .||... ..|||.|..| . .  . .|          
ql--------------vspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddle

Phosphatase PTC5.AA Subfamily.PDP.PD 143-220 43 6.9e-24 74.7 In-house 2-67 (409) Show / Hide
Range on Protein: 143-220
Range on HMM: 2-67/409
Sequence Identity: 43% (34 aa)

HFVNRGtGIFRYDVAQLPSNHPIEDDHVEqiitipiesedGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQL
..||.| .|.|||..||.||.||||...|           .|..|.. ..||.|||||| ...|..||.|..|||..|
ekvnkg-ailrydtnqLasNePiEDrrse-----------akllesngvlfgvfDGHggaacaeavskrLlkyvaasl

Phosphatase PTC5.AA Subfamily.ILKAP.PD 165-376 27 3.3e-18 55.9 In-house 23-214 (298) Show / Hide
Range on Protein: 165-376
Range on HMM: 23-214/298
Sequence Identity: 27% (58 aa)

IEDDHVEQIiTIPIESEDGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQvYDQNKTVfhsdpnQLIDSAISKGFLKLDNDLVIESFRklfQ
.|| || .   .  ... .||  . . ....||||.|. .|| . . | . .  .| .  |...        . |  .. . | | |...... .   . 
meDahviln-dldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpk-edvsakd------keikkclvdafkktDeeflklask---a

DPNNTniantlpaiSGSCALLSLYnsTNSILKVAVTGDSRALICGLDNEGN------WTVKSLSTDQTGDNLDEVRRIRKEhpGepNVIRNGRILGSLQP
|            .|| |   |    . .| ||  |||.|...  ..||.       .. .|| | |  . .| .||.||   |.|.||.||.|. ||..
kPvWk---------dGstavvvlv--vdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqka--G--gvvrdgRvlGvlev

SRAFGDYRYKIKEVDGKP
|| |.|  .|  .|    
sRsiGDgrfkelgvistP

Phosphatase PTC5.AA Subfamily.TAB1.PD 185-432 25 4e-18 55.3 In-house 31-271 (336) Show / Hide
Range on Protein: 185-432
Range on HMM: 31-271/336
Sequence Identity: 25% (67 aa)

SIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAyqLGQVYDQNKTVFHSDPNQLIDSAISKG------------FLKLDNDLVIESFRKLFQDPNNTNIA
. |.| . ...|||. |  ..|   . ||  .   ||.. .....  .  ..|.|.    |              || . .   .|..   .....|  .
rteddiilyavfdGydGekaaefveqrLvaell--lgdlseeaeaepkllllqvieeverkffesiddavaeradlkstlpkgvasyeleekyeekinrl

NTL-PAI-SGSCALLSLYnsTNSILKVAVTGDSRALICGLDNEGnWTVKSLSTDQTGDNLDEVRRIRKeHPGEPNVIRNGRILGSLQPSRAFGDYRYKIK
.| . |  |. |...|   .|  | ||  |||||...  ...|   || || | . || ||. |...    ... |.. ..||| .. |. |||. |.  
keleseisgGttavvali--lnnkLyvaNvGdsrAilvesekdg-ikvkQLsvdHnvdNedElkRlkd-LGldieqikqnkrlgskeaTRsiGdykikkg

EVDGKPLSDlpevAklyfrreprdfKTPPyVTAEPVITSAKIGENTK-FMVMGSDGLFELLTN
 . . ||.    |           | .| . |.| |. .|. .. . |... ||||.. | . 
ykevdvlss----A-----------kgeP-iiatPdingpkdindlegfllLmSdGlykalie

Phosphatase PTC5.AA Subfamily.PPM1L.PD 188-371 28 2.1e-14 43.4 In-house 40-198 (273) Show / Hide
Range on Protein: 188-371
Range on HMM: 40-198/273
Sequence Identity: 28% (52 aa)

KDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQvYDQNKTVFHSdpnqlidsaiskgflkLDNDLVIESfRKLFQDPNNTNIANTLPAISGSCALLSL
.  ||..|||||| |..|   . ||. .  .| . .|..|                     .. . ...  . |  | .  . |..   |.|. ||..| 
tgesffavfdGhGGefaaefakdvlvkaiknklie-ldadkentvp----------------infsklltd-eilsvdekllekakraediaGttalial

YNstNSILKVAVTGDSRALICglDNEGNwTVkSLSTDQTGDNLDEVRRIRKEhPGEPNVIRNGRILGSLQPSRAFGDYRYKIKE
.  .| | ||  |||| ...  |..|. ..  || |    .. | .||.|   |        |. | |  |||.|||  ||.  
vq--esdlivanvGdsrGvly--dkrGk-ai-plsfdhkpqqvkerkrikka-GGfiafrGvwrvaGvlatsralGdyplkdkn

Phosphatase PTC5.AA Subfamily.PPM1D.PD 169-338 22 2.7e-14 43.0 In-house 21-172 (311) Show / Hide
Range on Protein: 169-338
Range on HMM: 21-172/311
Sequence Identity: 22% (37 aa)

HVEQIITIPIESEDgKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQvydqnktvfHSDPNQLIDSAISKGFLKLDNDLviesfRKLFQDPNN
..| ...| .| |. .. |..  |...||||||   ..  .. |. ..  | .           |.... . .||...||.. . ..|  ..  .|  ..
ymeDvvaivleree-saeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkf---------lssepedvleAireaflatheam-----kkklaeWpk

TniANTLPAISGSCALLSLYnsTNSILKVAVTGDSRALICGLDN-EGNWTVKSLSTDQTGDNLDEVRRIRK
 |.. .|. | . .   ... | ||  |||....   .. | ... | | .|   ....|..||..     
t--ksgllstaGttasvvii--rreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkeriee

Phosphatase PTC5.AA Subfamily.PPM1K.PD 185-376 25 2.4e-13 39.8 In-house 32-196 (264) Show / Hide
Range on Protein: 185-376
Range on HMM: 32-196/264
Sequence Identity: 25% (46 aa)

SIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAyqlgQvydqnktvFHsDPNQLIDSAISKGFLKLDNDLVieSFRKlFQDPNNtniantLPAISGSCAL
.. ||..|..||||||. . .   ..| . |     .        .. . .. ..  . . |..||..|   .. . |. ...||. | .||    |  |
eldpdllyfavfdGhgGssaadfvhdkleeivr----r--------ll-ekekdleevlkqafeeldkklk--ryle-fsvaea------ellssGttat

LSLYNSTNSiLKVAVTGDSRALICgldNegNWTVKSLSTDQTGDNLDEVRRIRKEHP-GEPNVIRNGRILGSLQPSRAFGDYRYKIKEVDGKP
 .| .|||||..|      |   | |..| . .. .| .||..     | | . . .. . |  .|..|||   |  .|              
vsllrdGne-lvlaslGdsrailc---r--nGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryGviatP

Phosphatase PTC5.AA Subfamily.PPM1E.PD 186-368 29 6.5e-12 35.1 In-house 43-190 (269) Show / Hide
Range on Protein: 186-368
Range on HMM: 43-190/269
Sequence Identity: 29% (49 aa)

IEKDLYFFGIFDGHGGPFTSeklskdlvRYVAYQLGQVYDqNKTVFHSDPNqlidSAISKGFLKLDNDLVIESFRKLFQdpnntniantlpaiSGSCALL
||.  ||..||||||  ..        .| | .| ..   ... ...||     .|. ..| ..|. ..  . |. ..||| |   | .. .  | ||  
dekeraffavfDGHgGveaa--------kyaaahlhellv-rqeklkedpa----ealkeafkltDerflqkaereklk--------------sGstavv

SLYNSTNsiLKVAVTGDSRALICGldnegNWTVKSLSTDQTGDNLDEVRRIRKeHPGEPNVIRNGRILGSLQPSRAFGDYRYK
|||.||..      . .. .|      .. || .|| .   |   || . |. |.|. ||| ||...|               
vliekdq--lyvaWlGDsqallvr-----kgeavqlmkpHkPeredEkkRiee-agGlvvvigawRvnGvLsvsRaiGDvklk

Phosphatase PTC5.AA Subfamily.PPM1G.PD 279-371 35 1.7e-10 30.5 In-house 307-389 (482) Show / Hide
Range on Protein: 279-371
Range on HMM: 307-389/482
Sequence Identity: 35% (33 aa)

SGSCALLSLYNStnSILKVAVTGDSRALICGLdneGNwtVKSLSTDQTGDNLDEVRRIRKEhPGepNVIRNGRILGSLQPSRAFGDYRYKIKE
||. |. .| ..  . | ||  ||||. ..     |.     || |   ..  | .||.|   |  .|  .||. | |  |||.||. ||.| 
sGttavvaLvkg--kklivanaGDsRcvlsrn---Gk--aldlsiDhkPeDeveleRieka-GG--kvtldgRvnGGLnlsRalGDhaYktne

Phosphatase PTC5.AA Subfamily.PPM1H.PD 183-328 25 2.9e-09 26.0 In-house 57-206 (402) Show / Hide
Range on Protein: 183-328
Range on HMM: 57-206/402
Sequence Identity: 25% (41 aa)

GKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNK------TVFHSDPNQLIDsAISKGF---LK-LDNDLVIESFRKLFQDPNNTnIA
|. . .|..||.||||.|. ..   || | . .  .| .|..  .      . ....... ..   |. |    |   ..||| .. . |.. ..  ||.
skeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksaeklalgeerkeapt-epseifveekkiskeeLviGalesaflemDeq-ia

N--TLPAISGSCALL-SLYnsTNSILKVAVTGDSRALICGLDNEgnwtvKSLSTDQTGD
  .   |.| |. | .|.   .  | ||  |||||...  |.      . ||.| | . 
rereayrikGGCtalvalv--llgklYvanaGDsRailvrkdei-----iplsadftPe

Phosphatase PTC5.AA Subfamily.LRR-PP2C.PD 192-365 22 2.5e-08 23.4 In-house 42-179 (257) Show / Hide
Range on Protein: 192-365
Range on HMM: 42-179/257
Sequence Identity: 22% (38 aa)

FFGIFDGHGGPFTSEKLSKDLVRYVAYQLgqvydqnkTVFHSDPNQLIDSAISKGFLKLdndlviesfrklfqdpnntniaNTLPAISGSCALlSLYNsT
.. .||||||  ...  |..| . .|  |         .....| . .  |  .  ...                      .  ||. |  |..  ..  
yyalfdGhgGraaakfaseelykilaell--------dlnnanPlkslkkaykeistqi----------------------serpkfiGttaa-svli-i

NSILKVAVTGDSRALICgldnEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPNVIRNGRILGSLQPSRAFGDY
  .|  ||||...|    . . | | || |    . .| .||..      .     |. | |  |||.||    
edkvyianvGdsrvvlc----qkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds

Phosphatase PTC5.AA Subfamily.PPM1E.PD 394-447 24 6.6e-08 21.9 In-house 186-239 (269) Show / Hide
Range on Protein: 394-447
Range on HMM: 186-239/269
Sequence Identity: 24% (13 aa)

DFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNM
| |. |||..|. ... .. ..........|||.. ...||. .||  .. .. 
DvklkpyvsgeadvaeveldgsedylilacDGlwDvvneeevvklveefladga

Phosphatase PTC5.AA Subfamily.ILKAP.PD 401-454 20 2.5e-07 20.1 In-house 210-262 (298) Show / Hide
Range on Protein: 401-454
Range on HMM: 210-262/298
Sequence Identity: 20% (11 aa)

VTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNmNLAPVKA
|...| ..  ...|| .|.|.  |||.. ....|... ..  .... .   .| 
vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlede-ddrkikq

Phosphatase PTC5.AA Subfamily.LRR-PP2C.PD 397-446 28 8.5e-07 18.4 In-house 181-231 (257) Show / Hide
Range on Protein: 397-446
Range on HMM: 181-231/257
Sequence Identity: 28% (14 aa)

TPPYVTAEPVIT-SAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKN
|.|...| .. | .| .. ||...  ||...|...||  ..|.   | .  
lePfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivagisdpe

Phosphatase PTC5.AA Subfamily.PPM1G.PD 186-261 26 5.7e-06 15.6 In-house 34-97 (482) Show / Hide
Range on Protein: 186-261
Range on HMM: 34-97/482
Sequence Identity: 26% (20 aa)

IEKDLYFFGIFDGHGGpftseklsKDLVRYVAYQLGQVYDQNKTvFHSDPnqlIDSAISKGFLKLDNDLVIESFRK
...|  .|...|||||        |.  .|.| .| ..  ..|. .. .    ...|... |||.|. |. |.  |
ldedtslfavyDGhGG--------kevakycakklPdllkeska-ykegd---vekaleeaflkvDkkllteeilk

Phosphatase PTC5.AA Subfamily.PPM1H.PD 349-445 24 8.4e-06 14.7 In-house 276-355 (402) Show / Hide
Range on Protein: 349-445
Range on HMM: 276-355/402
Sequence Identity: 24% (24 aa)

NGRILGSLQPSRAFGDYRYKIKEVD--GKP-LSDLPEVAKLYFRREPRDFKTppyvtaepvitsakigentkFMVMGSDGLFELLTNEEIASLVIRWMDK
|.|. .  .| .||.  |. . .   || ||  |||  | ..   ..                        .....|||.. |.|||.|.| . ..|   
kaRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDd--------------------vlilatDGLWdvlsneevaeivrevlsk





Sequence
Name Sequence Type Origin Length Description Download
PTC5.AA Protein None 572 None Fasta, JSON
PTC5.NA RNA None 1716 None Fasta, JSON
PTC5.AA.PD_143-541 Protein Phosphatase Domain None 399 None Fasta, JSON