View source for Phosphatase Subfamily YMR1

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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]:  [[Phosphatase_Family_Myotubularin|Family Myotubularin]]: [[Phosphatase_Subfamily_YMR1|Subfamily YMR1]]

YMR1 encodes PI(3)P phosphatase found in fungi <cite>taylor00</cite>. It is the single myotubularin in most fungi.

===Evolution===
YMR1 is found in most fungi.

===Domain Structure===
YMR1 subfamily has three domains: [http://pfam.xfam.org/family/PF02893.15 PH/GRAM], phosphatase domain and coiled-coil domain. The GRAM domain is similar to PH domain in structure and is found in membrane-associated proteins.

===Catalytic activity and functions===
YMR1 of budding yeast encodes PI(3)P phosphatase, so does its ortholog in fission yeast  <cite>taylor00, blondeau00</cite>.

===References===
<biblio>
#taylor00 pmid=10900271
#blondeau00 pmid=11001925
</biblio>