Phosphatase Subfamily PP2D1

Phosphatase Classification: Fold PPM (PP2C): Superfamily PPM (PP2C): Family PPM (PP2C): Subfamily PP2D1

Evolution

The PP2D1 subfamily is found in frog, birds, platypus and mammals. It is also found sparsely from Trichoplax to fish, including Nematostella, Saccoglossus, Ciona, lancelets, and Tetraodon (but not zebrafish).

Domain

The PP2D1 subfamily has a single structural domain: the phosphatase domain. It has a predicted nuclear localization signal (NLS) using NLS mapper and NLStradamus.

Function

Human PP2D1 is predicted to be localized to the nucleus.