Phosphatase Superfamily HD

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HD is defined as potential metal-dependent phosphohydrolases [1]. Some members in the superfamily may encode (non-protein) phosphatases. Refer to Pfam database.


  1. Aravind L and Koonin EV. The HD domain defines a new superfamily of metal-dependent phosphohydrolases. Trends Biochem Sci. 1998 Dec;23(12):469-72. DOI:10.1016/s0968-0004(98)01293-6 | PubMed ID:9868367 | HubMed [Aravind98]
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