Phosphatase Subfamily PP2D1
From PhosphataseWiki
Phosphatase Classification: Fold PPM (PP2C): Superfamily PPM (PP2C): Family PPM (PP2C): Subfamily PP2D1
Evolution
The PP2D1 subfamily is found in eumetazoans but is frequently lost. It is absent from major model systems including Drosophila, C. elegans and the zebrafish.
Domain
The PP2D1 subfamily has a single structural domain: the phosphatase domain. It has a predicted nuclear localization signal (NLS) using NLS mapper and NLStradamus.
Function
The only publications on any member of the subfamily are showing high-throughput interaction between human PP2D2 and the amyloid protein Abeta []