Phosphatase Subfamily CG9801

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Phosphatase Classification: Fold PPM: Superfamily PPM: Family PPM: Subfamily CG9801

Evolution

CG9801 is found in metazoa but lost in deuterostomes. It is also found in some Amoebozoa. It is most closely related to the PTC7 subfamily, but their sequence similarity is very low

Domain Structure

CG9801 has a PPM phosphatase domain, with additional flanking conserved motifs that have not been annotated.

Function

The function of CG9801 is unclear. In Drosophila, it is reported to be subject to RNA editing [1], to be induced by ecdysone during moulting [2], and to possibly interact with the circadian clock [3]. The C. elegans homolog, F33G12.6, is uncharacterized. Dictyostelium tipA is involved in early development and tip formation [4].

References

Error fetching PMID 16356271:
Error fetching PMID 20041201:
Error fetching PMID 17018572:
Error fetching PMID 9169048:
  1. Error fetching PMID 17018572: [Stapleton]
  2. Error fetching PMID 16356271: [Beckstead]
  3. Error fetching PMID 20041201: [Dubruille]
  4. Error fetching PMID 9169048: [Stege97]
All Medline abstracts: PubMed | HubMed