Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ------------------------------------------------------------
Hsap_PHLPP1.AA MEPAAAATVQRLPELGREDRASAPAAAAAAAAAAAAAAAALAAAAGGGRSPEPALTPAAP
Hsap_PHLPP2.AA ------------------------------------------------------------
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ------------------------------------------------------------
Hsap_PHLPP1.AA SGGNGSGSGAREEAPGEAPPGPLPGRAGGAGRRRRRGAPQPIAGGAAPVPGAGGGANSLL
Hsap_PHLPP2.AA --------------------------------------------------MKRNGSRNCL
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ------------------------------------------------------------
Hsap_PHLPP1.AA LRRGRLKRNLSAAAAAASSSSSSSAAAASHSPGAAGLPASCSASASLCTRSLDRKTLLLK
Hsap_PHLPP2.AA NRRSRFG-----------------------------------------------------
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ------------------------------------------------------------
Hsap_PHLPP1.AA HRQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDTTAGEVAARLLQLGHK
Hsap_PHLPP2.AA --------SRERDWLREDVKRGCVYLYG--------------------------------
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ------------------------------------------------------------
Hsap_PHLPP1.AA GGGVVKVLGQGPGAAAAREPAEPPPEAGPRLAPPEPRDSEVPPARSAPGAFGGPPRAPPA
Hsap_PHLPP2.AA ------------------------------------------------------------
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ------------------------------------------------------------
Hsap_PHLPP1.AA DLPLPVGGPGGWSRRASPAPSDSSPGEPFVGGPVSSPRAPRPVVSDTESFSLSPSAESVS
Hsap_PHLPP2.AA ------------------------------------------------------ADTTTA
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA -------------MSDENLET---------------------------------------
Hsap_PHLPP1.AA DRLDPYSSGGGSSSSSEELEADAASAPTGVPGQPRRPGHPAQPLPLPQTASSPQPQQKAP
Hsap_PHLPP2.AA TTTTTTSSSSSSSSSSSDLHL-------------------------------------VL
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ------------------------------------------------------------
Hsap_PHLPP1.AA RAIDSPGGAVREGSCEEKAAAAVAPGGLQSTPGRSGVTAEKAPPPPPPPTLYVQLHGETT
Hsap_PHLPP2.AA CTVETPASEICAGEGRE--------------------------------SLYLQLHGDLV
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA ---ESTSKALEDILSY---------------TDSPAFRHIFSFFLGRPRIRAKSTLNLDI
Hsap_PHLPP1.AA RRLEAEEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKP--HSTGSSERIQ
Hsap_PHLPP2.AA RRLEPTERPLQIVYDYLSRLGFDDPVRIQEEATNPDLGCMIRFYGEKP--CHMDRLDRIL
Dmel_Phlpp.AA ---------------MLKATRKQADPYKSKLKVSA---SHSGP-HPLPVEVTAAEE----
Cele_F43C1.1.AA LSEEVVIRKGKL---IHTWQNARAVFYNSNIRLQT-KNNQDEALQIRNMKVDVHESKRGR
Hsap_PHLPP1.AA LSGMYNVRKGKMQLPVNRWTRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKH
Hsap_PHLPP2.AA LSGIYNVRKGKTQ--LHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKIEEVKRR
: . : : :.: : : *.
Dmel_Phlpp.AA ----------EQAATF--------------------------------------------
Cele_F43C1.1.AA ALRLK-----DDDVCYLIIFQRPNILEAWLTRAQQV--EKSNHVDASDEQLTLIPEQILN
Hsap_PHLPP1.AA QHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFY
Hsap_PHLPP2.AA QYSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVPEHLFY
: :
Dmel_Phlpp.AA ---------------GQTSP--------------------QKLSLKGSQLG---------
Cele_F43C1.1.AA NEARVQILNLRRNSLISRPPTEKSMAPLGYIDDLYRVHSLQVIDLSANQILSFPIQLTLL
Hsap_PHLPP1.AA SQD-LTHLNLKQNFLRQNPS----LPAARGLNELQRFTKLKSLNLSNNHLGDFPLAVCSI
Hsap_PHLPP2.AA SQD-ITYLNLRHNFMQLERP--------GGLDTLYKFSQLKGLNLSHNKLGLFPILLCEI
. : :.*. .::
Dmel_Phlpp.AA ------------------------------------------------------------
Cele_F43C1.1.AA SHLRQLNLSSNYISSVPSECSNMRRLQYLNLSNNQLDTLPDSISELQNLQSLDISFNQFS
Hsap_PHLPP1.AA PTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFT
Hsap_PHLPP2.AA STLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNNFS
Dmel_Phlpp.AA ------------------GSIL--------------------------------IGNYNY
Cele_F43C1.1.AA QIPPCLFHLT-LEMWRLAGNNIEKIDRVGEM----QIQKIDLRRNVLDTSFRLDIEN---
Hsap_PHLPP1.AA DIPEVLEKLTAVDKLCMSGNCVETL-RLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQH
Hsap_PHLPP2.AA QIPEVYEKLTMLDRVVMAGNCLEVL-NLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKH
*. : :
Dmel_Phlpp.AA LTQLEVCENEM-EVLDLSSLAQLETLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTN
Cele_F43C1.1.AA ITHLDLRDNSMISTVHLTNLRFLKVIHCERLQLSSLHLSGESLTHVYADHNLLDSL---V
Hsap_PHLPP1.AA VTQLDLRDNKL-GDLDAMIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQL---D
Hsap_PHLPP2.AA ITHVDLRDNRL-TDLDLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAV---N
:*:::: :* : : : :: ::* * :* * : * * : *. * * :
Dmel_Phlpp.AA THPVPLKLQRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLD
Cele_F43C1.1.AA VMPLPQNLQTLSLSFNHFRNLPDWISDCPNLTFLRANNNSLVALPE--RIFYSQSLRSIF
Hsap_PHLPP1.AA VYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPA--RLFCNSSLRKLL
Hsap_PHLPP2.AA VYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPV--RILSSLSLRKLM
. *:* * :.:* * : :*:* . .: : . * : :. * .* .:
Dmel_Phlpp.AA LAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNVSCNKLSTLP--
Cele_F43C1.1.AA AFINEIEHIPDFGEE-NCLETLILYKNKLSSLPKHFFSIL-PRLRQLNISSNFIELLP--
Hsap_PHLPP1.AA AGHNQLARLPERLER-TSVEVLDVQHNQLLELPPNLLMKA-DSLRFLNASANKLESLPPA
Hsap_PHLPP2.AA LGHNHVQNLPTLVEH-IPLEVLDLQHNALTRLPDTLFSKA-LNLRYLNASANSLESLPSA
* : .: * : * : * * ** :: * ** *.* :. **
Dmel_Phlpp.AA RYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEI
Cele_F43C1.1.AA YFDGSSFCRLQILRCANNYLTENSVPVIVNMKHLKIIDLSHNRLNSFDDSALSSLELLED
Hsap_PHLPP1.AA TLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEE
Hsap_PHLPP2.AA CTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEE
.. . * * :.* *.:. . : . :*.:: :: *.: : : : . **
Dmel_Phlpp.AA LVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTPQLAKLAMLKVLDLSHNHLDRVNLLA
Cele_F43C1.1.AA LNLSSNRLTRLADCLALLPCLQVLRAHSNQLVHVPEFRASNQLHTIDVSSNNISLGTLQF
Hsap_PHLPP1.AA IDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPE
Hsap_PHLPP2.AA LNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEILQLPQIQFVDLSCNDLTEILIPE
: **.* * :. : :..: . .* : *:. :: :*:* * : :
Dmel_Phlpp.AA LVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGNNRAALPTTKIRQVSAQ
Cele_F43C1.1.AA KAPP-NLRHFDVTCNSG-DFDTENFPE----NAKMHSKMNTINIS---------------
Hsap_PHLPP1.AA NLPP-KLQELDLTGNPRLVLDHKTLEL--------LNNIRCFKIDQ---PSTG-------
Hsap_PHLPP2.AA ALPA-TLQDLDLTGNTNLVLEHKTLDI--------FSHITTLKIDQKPLPTT--------
*. .*. :*:: * .: : : . : .
Dmel_Phlpp.AA RNQNKTSGPWTMGFAETPGSGDCRKLSVYQLRAANYGGSDEALYGMFEALEGRGRAAQEM
Cele_F43C1.1.AA -EGSQNLFGFQIGVSGSRGMKN--KQCIRQVRVENT-------FGFID-----GGSNSYM
Hsap_PHLPP1.AA -DASGAPAVWSHGYTEASGVKN--KLCVAALSVNNFCDNREALYGVFD-----GDRNVEV
Hsap_PHLPP2.AA -DSTVTSTFWSHGLAEMAGQRN--KLCVSALAMDSFAEGVGAVYGMFD-----GDRNEEL
: . : * : * : * .: : . :*.:: * :
Dmel_Phlpp.AA SHLVPDLMKQ---EQMVKDSAVRDYMKFTLLAAQQQCGSV--RSAALFHLTRTRAPSKVR
Cele_F43C1.1.AA SSSICRFMTSYLKENVSMD------IRSILLRCHCELGEEGERLGASVMIIRV--HEK--
Hsap_PHLPP1.AA PYLLQCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIK-HDPVD
Hsap_PHLPP2.AA PRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGSSALLCYIR-PDTAD
. : * . *:: : :: : : * . .. : .
Dmel_Phlpp.AA PLKSKRYVLRMASTGGLDAYLIRRTS-QLRLTKPDVIQKD------------------QI
Cele_F43C1.1.AA -------RLEIASTGTMSAAIARNQKLKMIINGRYEIDDD--EYSRIREAHGFVDEENRI
Hsap_PHLPP1.AA PGGS--FTLTSANVGKCQTVLCRNGK-PLPLSRSYIMSCE-EELKRIKQHKAIITEDGKV
Hsap_PHLPP2.AA PASS--FSLTVANVGTCQAVLCRGGK-PVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKV
* *..* .: : * . : :. :. : .:
Dmel_Phlpp.AA HSM-----------------PDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIRKE
Cele_F43C1.1.AA NGVIGSSRQIGHFSTFPVVLPTHSYRNIQLNEQIEGLIVGNNMIWNMLSIDDLNSTFHNN
Hsap_PHLPP1.AA NGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNV
Hsap_PHLPP2.AA NGVTCCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHV
:.: * . *. : * :::*. :*. :. ..:
Dmel_Phlpp.AA ENSLLAAKRLVDIAQSFAAAESLSVIVVRF----------------RHLGTDVDHLIREL
Cele_F43C1.1.AA RSPIVVAKKIQDQLQSYDYGGNSNILVLRR----------------IKPQMTFNGFSTSS
Hsap_PHLPP1.AA PDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSV
Hsap_PHLPP2.AA QDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEG-CTCEMN---GLTLPGPVGFASTT
..: .**.: **: . . :*: :
Dmel_Phlpp.AA KQSVRKKPQP-VSLPLSSGSVCKRTCCDRSNACRHRAIEQEPLAGRSSPSGQSDRDLLAK
Cele_F43C1.1.AA T---KNQVTPDIAIPKIDEQLVLAVPALI-----------------------LPEYHPSP
Hsap_PHLPP1.AA NMVIKDRPSDGLGVPSSSSGMASEISSELSTS--EMSSEVGSTASDEPPPGALSENSPAY
Hsap_PHLPP2.AA T--IKDAPKP--ATPSSSSGIASEFSSEMSTS--EVSSEVGSTASDEHNAGGLDTALLPR
. .. . * . : . .
Dmel_Phlpp.AA DKDDEFVLAHARVLQE-EQQLEMLDETESVSESVLSEEQFKCWEYMLEQNTQLLFDKELN
Cele_F43C1.1.AA P-------VPPPIPAIRHRTPSPP------------------------------------
Hsap_PHLPP1.AA PSEQRCMLHPICLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIH
Hsap_PHLPP2.AA P-ERRCSLHPTPTSGLFQRQPSSATFSSNQSDNGLDSDDDQPVEGVITNGSKVEVEVDIH
. .
Dmel_Phlpp.AA TISKSFTKQRTVPNAIMAATVLPERND---------FTSNLMRTVTNKFISTSTPQLPQP
Cele_F43C1.1.AA ------------PPPLPSSTPPPVSSE------------------------HEEINVRQS
Hsap_PHLPP1.AA C---SRAKEKEKQQHLLQ-VPAEASDE-----------------GIVISANEDEPGLPRK
Hsap_PHLPP2.AA C---CRGRDLENSPPLIESSPTLCSEEHARGSCFGIRRQNSVNSGMLLPMSKDRMELQKS
: .: . : .
Dmel_Phlpp.AA ITTSVPLGSYHQVKQAPPGHFGSALSFQQAHSYGYNLFDAKPRPKFHGGTVKRSAGPNSA
Cele_F43C1.1.AA ST-----------LSG-----GYTLSIDR-------------------------------
Hsap_PHLPP1.AA ADFSA-VGTIGRRRAN-----GSVAPQERSHNV-IEVATDAPLRKPGG------------
Hsap_PHLPP2.AA PSTSC-L--YGKKLSN-----GSIVPLEDSLNL-IEVATEVPKRKT-G------------
* . :
Dmel_Phlpp.AA YFGSLQRLMPYNFEYDFAVTQERERNILDEEEHDDDDFNEHES----RMRK---------
Cele_F43C1.1.AA FYSSSSTVSS---RKQF-------NETRDLLSKSL------------KLSP---------
Hsap_PHLPP1.AA YFAAPAQPDP---DDQFIIPPELEEEVKEIMKHHQEQQQQQQPPPPPQLQPQLPRHYQLD
Hsap_PHLPP2.AA YFAAPTQMEP---EDQFVVPHDLEEEVKEQMKQHQDSRLEPEPHEEDRTEP---------
::.: . :* : : .: .
Dmel_Phlpp.AA -YWGVATTEL
Cele_F43C1.1.AA --PNTVTFNI
Hsap_PHLPP1.AA QLPDYYDTPL
Hsap_PHLPP2.AA --PEEFDTAL
: