Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       PEPVLFFEVKEIIDNNVTFVWSGPSSDFEGYGLAIAPPINSFTSSLDEKEITIQVNTNKE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       FLASIYTYAGPWSSEPSTLNVIIDPREPGTIDVEELTSTSISITWTEFAGITDYIVNLTL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       ASNNTELFSGVIRSSLKASFSGLMPGEEYIIKIGLQCAGEVLSLRQYTLPLEPVCAVFTW
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       VTEDSVTLQWSRPESQLFGYEIMYDDGSGPYSPINVFDRNSLQLERTIMGLMDGPGVEVN
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       ITTLAGAGMTQTRSNPVKISPSSLGSAFNITTVTSTSIAFGWYDLPDASEYDVCIQQIMG
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       NATCRNVTEKTTEFSDLFPGAAYTFSLGWESACGVTLTFNTGQVTWDIPESEYDFFEVTY
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       SPDHGFTNSPAPIYRMDINENQTRVEFSFIGILPDTNYNVTVVTVVGALDVRSEPSYISF
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       RTESPANGSVAVTALSADSIQVGWGNNTQDYVNIRFNLDGENQTVCENEFICAVGNGSEF
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ----------------------MSKLPAPQPPGNVAVTEETTSTITLSWSPPSQEQFFGY
Spur_Spur_PTPRB5.AA       FNINDLQSGRKYHVFIDQDGVCGTLQQYTRPLPPVNIETADSQLTSLLIAWSDPGNETMF
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ----------MDFLIIFLLLFIGTSETQVDVSNVVPGTRYDITISSISTTYTSPVTRIVT
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ILEYEGTGFSTELGRTPATSFLPRHQESVTLKGLTPGISYSIKISSFVEYDDVTTRSNIV
Spur_Spur_PTPRB5.AA       DRYYVAYERADELGNFTEVGYLYPNVTSIFLEGLTPRTEYLFNVSTVVGEGKAQAFSDGE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            -------------------------------------------------MLYQLSKATTR
Dmel_Ptp4E.AA             --------------------MDCATRKQQQLRAHHQQQQIQIQTHGRKRQQLQKQRHNHH
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             --------MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCNRTIQNQQW
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ---------------------------MAGAGGGLGVWGNLVLLGLCSWTGAR-------
Hsap_PTPRQ.AA             TNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSK
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------MIRWKYELHSLIWLFLVLHLSKCQSDSLTT------
Spur_Spur_PTPRB3.AA       TSLGTTMSTSSLNIVAKFVNQTSFTIEWQPAVGASSYVTRVSEVTGVEISSVTNVNGDYE
Spur_Spur_PTPRB5.AA       LYSAYTAEANGTVTVFEYDTTSIMFTWPNMTSDLNVSISIIPNDGALDLNIGNRSAQVTG
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ---------------------------MVLTADQCSAAYRVSSQDETKTTIERTNLGN--
Dmel_Ptp10D.AA            IRLKRQKAVPQHRWLWSLAFLAAFTLKDVRCADLAISIPNNPGLDDGASYRLDYSPPFGY
Dmel_Ptp4E.AA             HYYQNSQQQQKHFVWLVVGILTIFLAQHANAADLVINVPNASS-NANAFYRIDYSPPFGF
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             MWTEDEKLLHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFLEVENASLFLQ
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             PDSLEVLLTNLNPGTTYEIKVAAENSAGIGV-----------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       RTEHRLVPGRNYQIEVSATGTGQSD-----------------------------------
Spur_Spur_PTPRB5.AA       LVPGRLYNISVLPFETIFQRTKPLPPYNVSICPDVGETFFSFCVRLTPPTGDYNAFYVLT
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            PEPNTTIASREIGDEIQFSRALPGTKYNFW------------------------------
Dmel_Ptp4E.AA             PEPNTTIPASDIGKDIKFSRALPGTEYNFW------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             KQGSRVVVKKARKYLHSWMKIDVNKEGKLVN-----------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       MDDFQAVQERRKRSPQEFGFDLAKRLGGNELETVLDDLVPDTGYTVQAVTVSGAGSMNEE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       CSAPVETIGRTLMIGETELVFTKVNSTAFRVWWNRDRNFTGNYNITAPPSDQQMLMSHDS
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       IPFADFEGVLSSTVYNVLVETGPSGSVAAGSVRTGYDLETLSPVERMLNGDPVEENPDSV
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       SNVFLTSLDEITLIASWDPPDVVTSSNEILLTLSTNSTEVRSVNVSGNVTEFVFKCLEPE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       TEYTVELVSLLQESGSFEKQYATETPPTATNSTVGLRPANESTPVVDSLTSTSIAVRWGR
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       LGQAGYSVCLVEYCRQRLDDPVCLTNNSDLCSIEGEFDSLDPGQLYIVSYMDPYGVSMEL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       EKVRTRPSPPSSVTITAVSSRLIEIRWTPPPNIAEMVLEYFDTESPSNTWEARIDNDGMY
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       DIHGLDADTSYTVRLSSVGRTGAGDGSDGKRLSGEPLEEVVRTSARILSVVNTANALTFL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             -------------------------------------------------FS--------D
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       WDEQPNPETFTGYLITSASINEVIPKQSEETSYQKSISNLTPGQLYEVSLFLQPITTFPA
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            -------------------------------------------------LYYTNFTHHDW
Dmel_Ptp4E.AA             -------------------------------------------------LYYTNSTHREQ
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             -------------------------------------------------ESLCLQKAGLG
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             -------APAPNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQ-------------
Hsap_PTPRQ.AA             PFLFQTAESAPGKVVNLTVEAYNASAVKLIWYLPRQPNGKITSFKISV------------
Spur_Spur_PTPRB2.AA       ----------------MRRASESCVGKETRSDYPALAEQLGEGGNVEH------------
Hsap_PTPRJ.AA             ------MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSP------------
Cele_dep-1.AA             -------SAEQHELFAIKKDSLSPWSQILVSLPRRHPLYQSFAAKIQD------------
Spur_Spur_PTPRB3.AA       -----TVEQRTLPSAVSNVDVVPEAAALTLSWDPVFGDVDGYYASYQL------------
Spur_Spur_PTPRB5.AA       PLDQLQVRTAPSPPESLRVVDETITTLRIEWDSPASGLYRGFEVDISPPTALQELPRIVG
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       -------RSTPSPSNTSQGAVTPSSSEASIPTRVSSSSVPSEEVNQTP------------
Dmel_Ptp10D.AA            LTWTVTITTAPDPPSNLSVQVRSGKNAIILWSPPTQGSYTAFKIKVLG------------
Dmel_Ptp4E.AA             LTWTVNITTAPDPPANLSVQLRSSKSAFITWRPPGSGRYSGFRIRVL-------------
Hsap_PTPRO.AA             ------------MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQ-------------
Hsap_PTPRB.AA             AEVSVRSTRNTAPPQILTTFNAVPDGLVFLIRNTTEAFIRNAAENYS-------------
Aque_Aque_PTPRB-1.AA      ------------------------MSLRITWTELLEDDQNGVIIGYNI------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       -----------------AIGTRASSLINLVAVPEAVGN----------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------EEALIEDDVFLPDYIELSPKPKTKKKNVIHKNRVS-------------
Spur_Spur_PTPRB4.AA       --------MMNREEGLLDDDVFQPDYIELSPTPKTKKKNVIHKNRVS-------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       SDIRGFTFVGLMHNSEYTVSVTTIMGEEGLEERSTTAEKTVMTARGDGDEVYLLSVSSTD
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       AEIGWTSPPLTMGYLDGSQITVSGQRTRIPDLTPGRQYTFTVNDVDLTFTTVPERPDGLE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ---------------------------------------------CTGDGGTTETRNTTA
Hsap_PTPRQ.AA             -----------------------------KHARSGIVVKDVSIRVEDILTGKLPECNENS
Spur_Spur_PTPRB2.AA       ------------------------------------------ARPGVPALVEPNHSNGKD
Hsap_PTPRJ.AA             -----------------------------IPDP----------SVATVATGENGITQISS
Cele_dep-1.AA             -------------------------------------VTENISDEVRDSNKTFVSSDDAP
Spur_Spur_PTPRB3.AA       -----------------------------KEDPYQISDLFYVSDPSNPTIRLTGLSPLSE
Spur_Spur_PTPRB5.AA       LESVGPYSLDWKVDTSLNDLNYERLEVSYSPESSQTDSPFDISRCTDGTFTLEGLQPDTE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       -----------------------------SPSNTSQRAVTPSSSEASILTRVSSSSVSSE
Dmel_Ptp10D.AA            ------------------------------------------LSEASSSYNRTFQVNDNT
Dmel_Ptp4E.AA             ------------------------------------------GLTDLPFERSYSLEGNET
Hsap_PTPRO.AA             -----------------------------DDNNIVVSLEASDVISPASVYVVKITGESKN
Hsap_PTPRB.AA             -----------------------------QNSSERQHPNLHMTGITDTSWVLSTTQPFSS
Aque_Aque_PTPRB-1.AA      ------------------------------------------SYFSLPAVGQPINNFTSD
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ---------------------------------------------------RPILLTDID
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             TNVTVDGLGPGSLYTCSVWVEKDGVNSSVGTVTTA-------------------------
Hsap_PTPRQ.AA             ESFLWSTASPSPTLGRVTPPSRTTHSSSTLTQNEI----------------SSVWKEPIS
Spur_Spur_PTPRB2.AA       SYIALTLFTVPSCPALVIPASE--------------------------------------
Hsap_PTPRJ.AA             TAESFHKQNGTGTPQVETNTSEDGESSGANDSLRT----------------PEQGSNGTD
Cele_dep-1.AA             YSIRIHALRAGHRYSIAIHGQKDGSTSL--------------------------------
Spur_Spur_PTPRB3.AA       YIITLTSFSGSGSDQEISSSTVEASTASSYVIEAS----------------DAGNVVHST
Spur_Spur_PTPRB5.AA       YSVSVTAISGDTRSDVLTRYGFTTCALEGQLHVVSLSSDEIALAWGPVNNIQGYAVRLFN
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       EVNQTTSEEPSKTPIPGEPGLRSSPRVASEYSVTT----------------IDVMTEGNT
Dmel_Ptp10D.AA            FQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNF-------------------------
Dmel_Ptp4E.AA             LQLSAKELTPGGSYQVQAYSVYQGKESVAYTSRNF-------------------------
Hsap_PTPRO.AA             YFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVN-------------------------
Hsap_PTPRB.AA             TTEETGLAEPERCNFTLAESKASSHSVSIQWRILG---------------SPCNFSLIYS
Aque_Aque_PTPRB-1.AA      TSYNISGLDVYTDYNVSVAAYTSAGTGPFDSVIRR-------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       THYDWLKADSENGLMKEYDGTGRGKFVQRLLGDCT-------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             --------------------------------------------------TAPNPVRNLR
Hsap_PTPRQ.AA             F--------------VVTHLRPYTTYLFEVSAATTEAGYIDSTIVRTPESVPEGPPQNCV
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             G-----------------------------------------ASQKTPSSTGPSPVFDIK
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       S-----------RALSQSRFIIISNLTPGTLYTIRITVTGSSERDTEIALTVPTAPRSLS
Spur_Spur_PTPRB5.AA       AIGINMRTLSLSANSMSATLDSLSPASNYSVQLIVMDTDGSRQTSVLQFVTDPAPPGPIT
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       S-----------------------------------------------SKSSATNGIAID
Dmel_Ptp10D.AA            -------------------------------------------------TTKPNTPGKFI
Dmel_Ptp4E.AA             -------------------------------------------------TTKPNTPGKFI
Hsap_PTPRO.AA             ---------------------------------------------------------GNV
Hsap_PTPRB.AA             SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVS
Aque_Aque_PTPRB-1.AA      -----------------------------------------------TDSTVPTSPSDVS
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ----------------------------------------------------------IS
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       --------------------------------------------------------KIEK
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             VEAQTNSSIALTWEVPDGPDPQNSTYG-VEYTGDGGRAGTRSTAHT--------------
Hsap_PTPRQ.AA             TGNITGKSFSILWDPPTIVTGKFSYRV--ELYGPSGRILDNSTKDLKFA-------FTNL
Spur_Spur_PTPRB2.AA       ---VTSMEIVATWPRPEGYTNVESYSI--SITPRTGVTYDSQIPNPFTSTNDMH------
Hsap_PTPRJ.AA             AVSISPTNVILTWKSNDTAASEYKYVV--KHKMENEKTITVVHQPWCN--------ITGL
Cele_dep-1.AA             ---IKEESVVMDPRAPDFRSMDSDIQVAEHNITMRTIKNDSYLQDSFSIE------YRQI
Spur_Spur_PTPRB3.AA       TDSISQSIVTVSWSQGLGNVDEYDIYL--RQAGESETPAQIVPPSQLTET------FENL
Spur_Spur_PTPRB5.AA       LQSSTQTRLSFTWTPATSNFDSYELSISGGDMPEPRPVGVVYPNEGNEFE------VGGL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       TDSSTPMAVLFTTLRKYDTSQDTDTQLPDTTSLDLTTVGKIVTRNPSDMPMTSVQ-VETT
Dmel_Ptp10D.AA            VWFRNETTLLVLWQPPYPAGIYTHYKV--SIEPPDANDSVLYVEKEGEPPGPAQAAFKGL
Dmel_Ptp4E.AA             VWFRNETTLLVLWQPPFPAGIYTHYRV--SITPDDAIQSVLYVEREGEPPGPAQAAFKGL
Hsap_PTPRO.AA             VTKPSRSITVLTKPLPVTSVSIYDYKP----SPETGVLFEIHYPEKYNV-------FTRV
Hsap_PTPRB.AA             KEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYT------FFNL
Aque_Aque_PTPRB-1.AA      YINISSTSIEVSWNPPTDFNGPNEGYVITYIRLESDTESMSTNRLTGT------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       VTQYATTTADVQWNLMQCSDCIYNYFL---------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       FQCSSRAVSAASAQKSYGTSAAFVQSL---------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             TPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLA------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             RPATSYVFSITPGIGNETW-----------------------------------------
Cele_dep-1.AA             NPDKKFPVLQILDIPEQKNL----------------------------------------
Spur_Spur_PTPRB3.AA       EPDTYYSMRIVSVVRAQNLEQRSIPAVTNFTTQPRIINVVETGRNLRLSWANDFGNDILK
Spur_Spur_PTPRB5.AA       LPDTTYNVRIYSVFFESRSIASEASFNT---DEQILEFNVGSNQNLTVSWQVQEGAESYR
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       EPSSVYSLVTELPLVTDLPTGL--------------------------------------
Dmel_Ptp10D.AA            VPGRAYNISVQTMSEDEISLPTTAQYR---------------------------------
Dmel_Ptp4E.AA             VPGREYNISVQTVSEDETSSVPTTARYL--------------------------------
Hsap_PTPRO.AA             NISYWEGKDFRTMLYKDFFKG---------------------------------------
Hsap_PTPRB.AA             TAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYR
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ---------EVESTQVRITWKKPRQPNGIINQYRVKVLVPETGIILENTLLTGNNEYIND
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       YQLIYIEDKEGATSNSEFVDPSDAPLVTLMNLMPGQTYTLILTAVDTLGNRAQIASTTYT
Spur_Spur_PTPRB5.AA       LIYTTTNRNTNSIARPATSTSITIDNLLFGAIYNFRLATIAADGTEMEVANADFVQRWHI
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             LMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAA------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             PMAPEIVNIVEPMVGLYEGSAEMSSDLHSLATFIYNSHPDKNFPARNRAEDQTSPVVTTR
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------GDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLLESI
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       L-----------KPLRPTFTVNRRSPSAVSLLGNLLGGILKFFRIRVTPQVTGAGAGTPI
Spur_Spur_PTPRB5.AA       ITNLVVFHDALCGPLTPSTNISDIKATTALLTFSLREGIFDDYVVMLSSPTDSCGARQPV
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------MPTDVSQTMQTSLPSAQSTALSTDEQPLEVSTLFDGGTDGTPSAFDPV
Dmel_Ptp10D.AA            ------------TVPLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATTRRQS
Dmel_Ptp4E.AA             ------------TVPERVLNVTFDEAYTTSSSFRVRWEPPRTYSEFDAYQVMLSTSRRIF
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------GLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNIT
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       FTLSREACPELLLLDLYPNTMYTAQVFARTGERGLSLPSETTLQNFTTATVVNNEVEISK
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ----------------------------------------NITVDGLEPGCLYAF-----
Hsap_PTPRQ.AA             ----------------------NQYITDIAAEQL------SYVIRRLVPFTEHMISV---
Spur_Spur_PTPRB2.AA       ----------------------------------------RAVFSSLTPAQTYVIEV---
Hsap_PTPRJ.AA             ----------------------GSHEELTQDSRL------QVNISGLKPGVQYNINP---
Cele_dep-1.AA             ----------------------------------------EFYLGNLNSGFDYSVRV---
Spur_Spur_PTPRB3.AA       ----------------------NIDVLIPVEACP------EIELTGLIPNRDYQVTL---
Spur_Spur_PTPRB5.AA       VGTNSLEIIWKTDNVDEYLLHYSGPDGPLMSDIVPYIEINYYTFGELTPGTQYSISVISL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ----------------------SLEATTRLDETF------FDTTEA--GTLPTTTVS---
Dmel_Ptp10D.AA            ----------------------TVPRSNEPVAF-------FDFRDIAEPGKTFNVIV---
Dmel_Ptp4E.AA             ----------------------NVPRAANGDSVY------FDYPDILEPGRTYEVVV---
Hsap_PTPRO.AA             ----------------------------------------KTVFNHWLPGMCYSNITF--
Hsap_PTPRB.AA             ----------------------LSHKGTIKESRVLAPWITETHFKELVPGRLYQVTV---
Aque_Aque_PTPRB-1.AA      ----------------------------------------SFVIENLEKYEQYSVTV---
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             --------SMWVGKNGINSSRETRNATTAHNPVRNL-RVEAQTTSSISLSWEVPDGTDPQ
Hsap_PTPRQ.AA             --------SAFTIMGEGPPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNGK
Spur_Spur_PTPRB2.AA       --------TANAINAGPESPAGCNSIPVVAKPAAVVLQVANFNTTSVSLAWSVPLSVTPD
Hsap_PTPRJ.AA             --------YLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESLVGPV-------
Cele_dep-1.AA             --------IAHKDGMSSRPWISTLTTKP---SPLKEVNINQNAGSCVEVSWQNDEFSGAD
Spur_Spur_PTPRB3.AA       --------QAESGVASSDPQIITFTTPPL--TQQGELSFGEITPSGFTVYWTP-------
Spur_Spur_PTPRB5.AA       INRERQGDALEVMQYTKPDPISNLVLTPQENTINLTWTSPSTMYDGFLICWYSATTEDNK
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       --------PLEVGSIGTIEAVTDLGMTEETNPATDLQEMETDLLTGEEVEGTPPLELWTI
Dmel_Ptp10D.AA            --------KTVSGKVTSWPATGDVTLRPL--PVRNLRSINDDKTNTMIITWEADPASTQD
Dmel_Ptp4E.AA             --------KTIADNVNSWPASGEVTLRPR--PVRSLGGFLDDRSNALHISWEPAETGRQD
Hsap_PTPRO.AA             --------QLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQS
Hsap_PTPRB.AA             --------SCVSGELSAQKMAVGRTFPD---KVANLEANNNGRMRSLVVSWSPPAGDWEQ
Aque_Aque_PTPRB-1.AA      --------VAFTDKGPGASSDVLSVLTDEDLPGPPSNVSTMSTNTSISITWSPPLDPNGL
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------LTFEPDSQEPIRVDYTT-------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       --------RGEGAMTVQARPAERSARVLRAMPVRGMFNATSDMSTGYGLTIQA-------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             -----------------------------------------NSTYCVQCTGDGGRTETRN
Hsap_PTPRQ.AA             --------------------ITHYTIYAMELDTNRAFQITTIDNSFLITGLKKYTKYKMR
Spur_Spur_PTPRB2.AA       ---------------------------------------GYVLTIDILSADADPAPVDIP
Hsap_PTPRJ.AA             -----------------------------------------------------DPSSGQQ
Cele_dep-1.AA             ---------------------------------------FYTIQYSLQSTPNNSTNMTIP
Spur_Spur_PTPRB3.AA       ----------------------------FLGRTSYELSINNQAGLVVPASGDAVQSYVVD
Spur_Spur_PTPRB5.AA       AWLDGDATTYPWVISTPNEEYVVSVATFVGDREGDYVLSNKVTDFITLTETSPLILKDIA
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ---------------------------ETSSEEVTEFDFPNDLSTELMASTEATTTIETP
Dmel_Ptp10D.AA            ---------------------------------------EYRIVYHELETFNGDTSTLTT
Dmel_Ptp4E.AA             -----------------------------------SYRISYHEQTNASEVPAPFPVAAES
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             YRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVP
Aque_Aque_PTPRB-1.AA      -------------------------------------LLSYSINVTLNSTYAQYLSFDVM
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             TTDTR-------------------------------------------------------
Hsap_PTPRQ.AA             VAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTADEIRLKWSPPEKP------
Spur_Spur_PTPRB2.AA       GADTA-------------------------------------------------------
Hsap_PTPRJ.AA             SRDTE-------------------------------------------------------
Cele_dep-1.AA             STESSI------------------------------------------------------
Spur_Spur_PTPRB3.AA       GLSSGTEYTVSLVDGGTGAIRTRPLAPGTPLATQVLDTSIQLQWAQSSDGNVAG------
Spur_Spur_PTPRB5.AA       TDTISVSWVTIPGVVDYTLSYSPPDGNEQATQDIDESSAIAEGLNNIYYVNFTGLTPGRE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       VIPAP-------------------------------------------------------
Dmel_Ptp10D.AA            DRTR--------------------------------------------------------
Dmel_Ptp4E.AA             QITTNLTE----------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             LAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKE--------
Aque_Aque_PTPRB-1.AA      TMSVSQNIFS--------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       YTFTVVWPLAFNYSTDAIRTNPLPIYDPSVTNTTSCNLLYQWCLPDSDFDNISITIVPDV
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       SMRTLSRGNGTGGMCDYQTVYLDGLEPATSYNVSVEVMSGDKSSEVVMVYSTTEPLPVNN
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ---------------------------------------------------VTVDGLGPG
Hsap_PTPRQ.AA             -------------------NGIIIAYEVLYKNIDTLYMKNTSTTD------IILRNLRPH
Spur_Spur_PTPRB2.AA       ---------------------------------------------------YVVPSLLPG
Hsap_PTPRJ.AA             ---------------------------------------------------VLLVGLEPG
Cele_dep-1.AA             ---------------------------------------------------SICDSMLQG
Spur_Spur_PTPRB3.AA       -------------------YEICYSPDDGSSPVYIAGRTTTQ---------YTLEGLDSD
Spur_Spur_PTPRB5.AA       VTLDDSTIFTLTISWENPIDGSFNMFLVEYAPVRSPDSVMALDPINMGTNTAIIPNLQPG
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ----------------------------------------------------CLCDVESD
Dmel_Ptp10D.AA            ---------------------------------------------------FTLESLLPG
Dmel_Ptp4E.AA             ---------------------------------------------------YTLDSLLAG
Hsap_PTPRO.AA             -------------------------------------------------------GNFPE
Hsap_PTPRB.AA             ---------------------------------------------------FTFTDLVPG
Aque_Aque_PTPRB-1.AA      ---------------------------------------------------YTLFDLLPF
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ---------------------------------------------GVNEYSYQVSGLTEG
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ----------------------------------------------------------KY
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             SLYTCSVWVEKDGVNSSVEIVTSA------------------------------------
Hsap_PTPRQ.AA             TLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDS--------------------------
Spur_Spur_PTPRB2.AA       VEYSFTVQAYQNVQSTRAFGETDTVMQR--------------------------------
Hsap_PTPRJ.AA             TRYNATVYSQAANGTEGQPQAIEFRTN---------------------------------
Cele_dep-1.AA             EAYQIIATVQKGGQVSEPLITKFQLR----------------------------------
Spur_Spur_PTPRB3.AA       TTYIISISALTGVPQVKSQKQTIFVTTIADTTIP--------------------------
Spur_Spur_PTPRB5.AA       TLYNIMVYALAGEERSDATEITAMTRQQNSEELRLQTRTSTSISVSWGNTTRPEVTGFVL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       LLSASVCLCNTSLALSNFTYRAHLVRRNHD------------------------------
Dmel_Ptp10D.AA            RNYSLSVQAVSKKMESNETSIFVVTR----------------------------------
Dmel_Ptp4E.AA             RRYLIAVQALSKGVASNASDITRYTR----------------------------------
Hsap_PTPRO.AA             ESFMRSQDTIGKEKLFHFTEETPEIPSGNI------------------------------
Hsap_PTPRB.AA             RKYMATVTSISGDLKNSSSVKGRTVP----------------------------------
Aque_Aque_PTPRB-1.AA      AGYDISLQASTSVGLGTPAIETETTLQ---------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       RNYNFTVVSVSGVGVQDATLK---------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       EHSRVKLMALKGKSETDYINA---------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       RITFQEGDAIDSIKNVSLGDVLGVEFSDLIPGTNYTVYLLVEVEGQLDTAVHSLDVTTLP
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             -APENITYKNISSGEIELSFLPPSSPNGIIQKYTIYLKRSNGNEERTINTTS--------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             -AIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSE--------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       -VASNFAVTNTQAADHVIILEWDVPERASYDYFEVSYTPDVGYPSSPVRLPK--------
Spur_Spur_PTPRB5.AA       GMPGNISCDPTKTTQSLLEIEWGSTQEGNFDGYAISTQTGDGEEIPLESVEKDEQLQATA
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       -NRTHPEVQVHAALISSGSGCWNISVPLGGS-----------------------------
Dmel_Ptp10D.AA            --PSSPIIEDLKSIRMGLNISWKSDVNSKQEQYEVLYSRNGTSDLRTQKTKE--------
Dmel_Ptp4E.AA             --PAAPLIQELRSIDQGLMLSWRSDVNSRQDRYEVHYQRNGTREERTMATNE--------
Hsap_PTPRO.AA             -SSGWPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNS-------------
Hsap_PTPRB.AA             -AQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNESISSET--------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       DYLMDNTIYTFIVRSTLGDLRGEPTTMTCRTDPQNLMVSTSTSPSGGQEVFLDWQDYGAS
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       SYKVEYTPQEGTPSSPIFLDTRQLILRNLSPGTAYHFTLHYTATGSTTGVTFVLAPLPVV
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------LTQNIK
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------PRAVIP
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------AATSLS
Spur_Spur_PTPRB5.AA       QVIIVLRRPTSFTIQITLPRRGRYRFLRLRVRRRSQGLDAGPDGDEFLIPTDACPEYTFN
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            --------------------------------------------------------SRLV
Dmel_Ptp4E.AA             --------------------------------------------------------TSLT
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             --------------------------------------------------------SRYS
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ----------------------------------TAPNPVRNLTV-EAQTNSSIALTWEV
Hsap_PTPRQ.AA             VLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSV-KQLSGVTVKLSWQ-
Spur_Spur_PTPRB2.AA       ----------------------------------TTPVPPENIAI--EVTETTATITYEA
Hsap_PTPRJ.AA             GLRSS--TFYNITVCPVLGDIEGTPGFLQVH---TPPVPVSDFRV-TVVSTTEIGLAWS-
Cele_dep-1.AA             ------------------------------------PLPPIDFRVRADLKRGKYKLLAEL
Spur_Spur_PTPRB3.AA       IMNALADKVYQFSLVSIRGDERTDPPLTTTG---QIAVNNLIVVI-GERTTTSLEILWGA
Spur_Spur_PTPRB5.AA       NLLPDTDYAVDVNTVAEDGRTESSPSTMDVT---TPRMEEGDISF-NEVTTTSISFAWGM
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       -------YKLVVTAEDGLGNLVSTPTAYFYS---GLMPPFLSVKK-VPGAIPSLELYWQI
Dmel_Ptp10D.AA            IKNLQPGAGYELKVFAVSHDLRSEPHAYFQA---VYPNPPRNMTI-ETVRSNSVLVHWSP
Dmel_Ptp4E.AA             IHYLHPGSGYEVKVHAISHGVRSEPHSYFQA---VFPKPPQNLTL-QTVHTNLVVLHWQA
Hsap_PTPRO.AA             ----------------------------------TLSETEKSTSGSFSFFPVQMILTWLP
Hsap_PTPRB.AA             FHSLKSGSLYSVVVTTVSGGISSRQVVVEGR---TVPSSVSGVTVNNSGRNDYLSVSWLL
Aque_Aque_PTPRB-1.AA      ----------------------------------AAPAAPVANPMASPVSSTAVNVSWLP
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ----------------------------------TSEEESVDQ-----------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             PDGP--DPQNSTYGVEYTGDGGRAGTRSTAHTN--------ITVDR--------------
Hsap_PTPRQ.AA             PP-LEPNGIILYYTVYVWNRSSLKTINVTETS---------LELSD--------------
Spur_Spur_PTPRB2.AA       P-----------------------------------------------------------
Hsap_PTPRJ.AA             ------SHDAESFQMHITQEGAGNSRVEITTNQS-------IIIGG--------------
Cele_dep-1.AA             PT----SSKIDKCQITVAGDEAERSVNYANIEQTKSGHKICWFNFA--------------
Spur_Spur_PTPRB3.AA       SA-S---GSVDEYQVSYVGSTPIVVDGSSDRR---------VVIPG--------------
Spur_Spur_PTPRB5.AA       VS-ADTNGPFDFYLLNLKNELSIDVQNVQVNTSETREHTFIGLMPGELYRVELIVNSNRQ
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       PY-P---TYVDDVTIFVSKDDALATELTWMRVGGVRTSGQ-FTFVA--------------
Dmel_Ptp10D.AA            PE----SGEFTEYSIRYRTDSEQQWVRLPSVRSTE------ADITD--------------
Dmel_Ptp4E.AA             PE----GSDFSEYVVRYRTDASPWQRISGLHENE-------ARIKD--------------
Hsap_PTPRO.AA             PKPP---TAFDGFHIHIEREENFTEYLMVDEEAH-------EFVAE--------------
Hsap_PTPRB.AA             AP-----GDVDNYEVTLSHDGKVVQSLVIAKSVRE------CSFSS--------------
Aque_Aque_PTPRB-1.AA      PNLSNWNGLITNYTIEYRTNDEY-------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       -----------------------------------------NYIPG--------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       RSAPMYTRPDKPTDIMLSDLTTTSLTIDWKAPLTSYQGFRLCWAYGETNSLELGPAVMER
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ----LEPGCLYVFSVWVGKNGINSSRETRNA-----------------------------
Hsap_PTPRQ.AA             ----LDYNVEYSAYVTASTRFGDGKTRSNIISFQTPE-----------------------
Spur_Spur_PTPRB2.AA       ----LGFHSNFTHTLLDDGGNE--------------------------------------
Hsap_PTPRJ.AA             ----LFPGTKYCFEIVPKGPNGTEGASRTVCN----------------------------
Cele_dep-1.AA             ----LSPGERFDFSISSMANESASQKLQKSI-----------------------------
Spur_Spur_PTPRB3.AA       ----LSPGTEYTVTVQAINAGAAVGDSMETASTLHEINGLSAMVTDQASSMIHLTITPPF
Spur_Spur_PTPRB5.AA       TLSDLEAGAEYLVSLAAVVGTGANQITSEKFTTIVTLFPPAELHVNITSFNTTAVSIVWG
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ----SGLGSKYSVAVVIASGAKSVTSNYDTV-----------------------------
Dmel_Ptp10D.AA            ----MTKGEKYTIQVNTVSFGVESPVPQEVN-----------------------------
Dmel_Ptp4E.AA             ----MHYGERYLVQVNTVSFGVESPHPLELN-----------------------------
Hsap_PTPRO.AA             ----LKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWI--------------
Hsap_PTPRB.AA             ----LTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATG
Aque_Aque_PTPRB-1.AA      ----IRPSIEVTATLSSFANSDDPRA----------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       EDPMRYDGYNVRVRLGGVSSPVVQPVIPVAKSACPEIWIKKLEAATMYEIDIEWYSGLDI
Spur_Spur_PTPRB5.AA       TDIPLLDVSSYVVSYWETANNGSVQDISVDDPSQTDYTIDGLVPGTRYSFMVDALGTVQA
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             DFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNG--
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             --------TTAPNPVRNLHMETQ--TNSSIALCW--------------------------
Hsap_PTPRQ.AA             --------GAPSDPPKDVYYANL--SSSSIILFWTPPSKPNGIIQYYSVYYRNTSGTFMQ
Spur_Spur_PTPRB2.AA       --------VRGPDGSNEFSVEYM-------------------------------------
Hsap_PTPRJ.AA             --------RTVPSAVFDIHVVYV--TTTEMWLDW--------------------------
Cele_dep-1.AA             --------VLTPAFDFNAFGLTLQESNGGIELIW--------------------------
Spur_Spur_PTPRB3.AA       SEAFRVQTSTVAAAPLDITLDEL--ETDSMKVSW---QEGTGSFSNYLVTYSPVGSTQTP
Spur_Spur_PTPRB5.AA       VTSIGATQYTNPETVAEIRVIPS--ITCSVRLEW---DRPEGNLDSYIFHYNVTRGTIVG
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       --------VIAPQHPHTVRVASI--SSELLTMQWPHDPSSCTAACSYLVRYQ--------
Dmel_Ptp10D.AA            --------TTVPPNPVSNIIQLV--DSRNITLEW---PKPEGRVESYILKWWPSDNPGRV
Dmel_Ptp4E.AA             --------VTMPPQPVSNVVPLV--DSRNLTLEW---PRPDGHVDFYTLKWWPTDEEDRV
Hsap_PTPRO.AA             --------EELTEKPQHVSVHVL--SSTTALMSWTSSQ----------------------
Hsap_PTPRB.AA             --------RTIPEPVKDLTLRNR--STEDLHVTW---SGANGDVDQYEIQLLFNDMKVFP
Aque_Aque_PTPRB-1.AA      --------ATTPLQLESIIIPSL-------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ----------MPAYITAIDIPYP-------------------------------------
Spur_Spur_PTPRB9.AA       --------RTVPATPSDLSIVP---GQRELNLVW--------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       --------FNSPREYIACQGPLPETTNDMWRMIW--------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             NFTLHEVTNDFDNMTVSTI-----------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       MLVAKGEPRVLDLSGLVPGTAYTIMVQQQGQTPAQETHVQLTLPEAINIDSLSVTRSKNA
Spur_Spur_PTPRB5.AA       APLQLDVAINDTAETLTYLLEGLEKDSSSDFVSLEVGVTTVAGAGEDQVESLQQVVKDLD
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            QTKNVSENKSADDLSTVRVL----------------------------------------
Dmel_Ptp4E.AA             EFKNVTQLEDLSSPSVRIP---IEDL----------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             -----------------EVPDGPYPQDYTYW----------------------VEYTGDG
Hsap_PTPRQ.AA             ------------IDKLTIFSYYTFWLTASTS----------------------VGNGNKS
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             -------------KSPDGASEYVYHLVIESK----------------------HGSNHTS
Cele_dep-1.AA             -----------------PKSEVFMTRVKDIW----------------------NKVVGAE
Spur_Spur_PTPRB3.AA       LDATWSAPS---TGNYDGYRVCHYPRGTQNS----------------------PFTSGTT
Spur_Spur_PTPRB5.AA       VNVVTITILGRDQNSIQAEVNSSVSNVESIT----------------------TGLYNDE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------QTSPYNYNSNPVTELPVRC----------------------PGLLAAQ
Dmel_Ptp10D.AA            ------------IGELMPGVQYKFDIQTTSY-----------------------GILSGI
Dmel_Ptp4E.AA             ----------------SPGRQYRFEVQASSN-----------------------GIRSGT
Hsap_PTPRO.AA             ----------------ENYNSTIVSVVSLTC----------------------QKQKESQ
Hsap_PTPRB.AA             SLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGS
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       -----------------EKKSTIIVMMTQTV----------------------EGGK---
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             GGTETR------------------------------------------------------
Hsap_PTPRQ.AA             SDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTPRH--
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             T-----------------------------------------------------------
Cele_dep-1.AA             SLLNMRITPIGNNDETDKTLKFE-------------------------------------
Spur_Spur_PTPRB3.AA       PSINLPGLNSLTYYLVTVSSSEESTYSEPTTITQQTLIGDPGDINIALEDVDTNSVRITW
Spur_Spur_PTPRB5.AA       MVTSSTTRNCSTTDCESFTVDFDTLNSGTLYTLYAGVVQSSGREVVPLLAKAATIPESAV
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       PARSTS------------------------------------------------------
Dmel_Ptp10D.AA            TSLYPRTMPLIQSDVVVAN-GEKEDERDTITLSYTPTPQSSSKFDIYRFSLGDAEIRD--
Dmel_Ptp4E.AA             THLSTRTMPLIQSDVFIANAGHEQGQDETITLSYTPTPADSTRFDIYRFSMGDPTIKD--
Hsap_PTPRO.AA             RLEKQY------------------------------------------------------
Hsap_PTPRB.AA             LKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRN--
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       VAINSITR----------------------------------------------------
Spur_Spur_PTPRB5.AA       DLQFTSIGRNYVVLTWDNPAGMIDSYNISYYPVNDITKLMFEVVQAAAESNVLRVDDLNE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       GMNYSFTVVSLLEVEADLQEMGAPVEVFAVVGVLGSLNITAFDETTISIEWEQVDVEEYI
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ----------------NTTNTSVTAERLEPGTLYTFSVWAEKNGARGSRQNVSISTV---
Hsap_PTPRQ.AA             -----------VRPPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEE
Spur_Spur_PTPRB2.AA       --------------------------DLTAGTMYTYRVLSNAGSATSEAVLQTFTSR---
Hsap_PTPRJ.AA             ------------------YDKAITLQGLIPGTLYNITISPEVDHVWGDPNSTAQYTR---
Cele_dep-1.AA             --------------TSPKNIDPVFAKNLVKGACYRVQLFTVTKTGIISETRHNETIR---
Spur_Spur_PTPRB3.AA       YTVGGGTGASQTVTVNSPEEAEYTFTNLVPGTSYTFFVTP-----LGTQRREREQYT---
Spur_Spur_PTPRB5.AA       LSYDALEGGSGNVTVQSTDPNSYTFTGLTPGTQYTIGVQPGIYAALEKTQSTV-------
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       --------------PNAMNTCTEYLRDLIPGALYDIDVYASSYGVLSVTAAQLRQRT---
Dmel_Ptp10D.AA            -----------KEKLANDTDRKVTFTGLVPGRLYNITVWTVSGGVASLPIQRQDRLY---
Dmel_Ptp4E.AA             -----------KEKLANDTERKLSFSGLTPGKLYNVTVWTVSGGVASLPVQRLYRLH---
Hsap_PTPRO.AA             --------------CTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAI---
Hsap_PTPRB.AA             -------------TSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTV---
Aque_Aque_PTPRB-1.AA      ------------------------------HEFVNYSFIITLSNSIGQISSLPVHIVTLE
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       --------------------------NKMKREVIQLQFTSWPDHGVPEQTKPMLDFV---
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ---PNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTD--
Hsap_PTPRQ.AA             DVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFITSDNY----
Spur_Spur_PTPRB2.AA       ---PNPPGIPEPTFVDETTITIQWAHN-SGERDEYEVSYSPNGTSFTPQTPQYVIENR--
Hsap_PTPRJ.AA             ---PSNVSNIDVST-NTTAATLSWQNF-DDASPTYSYCLLIEKAGNSSNATQVVTDIGIT
Cele_dep-1.AA             --MSSPAVNVSLESVTRSSATLRIVFSTHHDSTSISNCQMHIVVRDMNGKSVFDKRMQLT
Spur_Spur_PTPRB3.AA       --RPDMPRNLLFNTITTNSISIGWEKPLTGGVDSYRVTYSPSSDGSPASPHTITDNGQIT
Spur_Spur_PTPRB5.AA       ---PNPPTNLRTTMVAAQSITVSWDPPSEGGSDTYNITYNVTGGQPPSPHTVSTSETS--
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       --PPTPPQNVTVTNVTEQSITIAWTPGAGYRTRYHLHAYATSYSEEVGVVHGDVTD----
Dmel_Ptp10D.AA            ---PEPITQLHATNITDTEISLRWDLP-KGEYNDFDIAYLTADNLLAQNMTTRNE-----
Dmel_Ptp4E.AA             ---PLPISDLKAIQVAAREITLHWTAP-AGEYTDFELQYLSADEEAPQLLQNVTKNTE--
Hsap_PTPRO.AA             --VPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAAT
Hsap_PTPRB.AA             ---PAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS---
Aque_Aque_PTPRB-1.AA      STPSGPPLDVSVIVDSPSTARISWSPPMYIDRNGIIVNYTVRIITTVRGTIRETNISNVS
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ----------------------------AYQGDADNFTITVTPNQGIAMFNGDFNDPA--
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ----KNVREHIRKKCVIKPVVVHCSAGVGRTGTYIALDRLTQHMEDNDFVDVC-------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------ITLKELEAGSLYHLTVWAERNEVRGYN---------------------------
Hsap_PTPRQ.AA             ------IILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSD
Spur_Spur_PTPRB2.AA       ------FVLTGLDPYTTIQFDVRTVVNSVTSTP---------------------------
Hsap_PTPRJ.AA             D-----ATVTELIPGSSYTVEIFAQVGDGIKSL---------------------------
Cele_dep-1.AA             ATFAPLLNLDGLSPFHKYTVNTQIICGSGSSET---------------------------
Spur_Spur_PTPRB3.AA       QT----LTVTNLLPGTTYTFNVYALVAELVSEP----VTRGSGTTIGMDIGAGYTSTQFT
Spur_Spur_PTPRB5.AA       ------VTFSNLTPLTEYFFTIVNIWKSLPSRS--ELTRATTSAQTLSLAVTPEDNTEFT
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------FTFHNLLAGTRYIITIRASANDTDGDM---------------------------
Dmel_Ptp10D.AA            ------ITISDLRPHRNYTFTVVVRSGTESSVL---------------------------
Dmel_Ptp4E.AA             ------ITLQGLRPYHNYTFTVVVRSGSIQGTD---------------------------
Hsap_PTPRO.AA             VSLTASVRIANLLPAWYYNFRVTMVTWGDPELS---------------------------
Hsap_PTPRB.AA             ------FSFQNLLQGRMYKMVIVTHSGELSNES----FIFGRTVPASVSHLRGSNRNTTD
Aque_Aque_PTPRB-1.AA      GNY---YDASDLPQFASFNVTVAAATSVGLGPY---------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------AEVTGLTPGTMYDIAIVTASGDERSEP---------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------GVVCEMRMHRNYLVQTEVDSSRAGSHS---------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             FVWLKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSA
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       VVWNVPTSGDFNQFQVTYDPYDPTNAQESPRIISLSSLNGAQEGSLLIYGLEPGQLYNVY
Spur_Spur_PTPRB5.AA       VSWEDLDTEAFEQYCVMYEPYEAQENRQQESF--PVARNIRSARFYGLDPGQEYTVYVTS
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             SLWFNWSPASGDFDFYELILYNPNGTKKE-------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             FTKVGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKANGIITQYMVTV
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       VQTMLNGLQTDDGFGRISFRTPPLPVTGVVITQRTPYSLSLDWSDVISADIQYRITYAPL
Spur_Spur_PTPRB5.AA       CSSVSDPTSHANERISFRLDPAAIAEIRIMDGSLGPRAVMLEWDQPEGIRGLYEVTLDPA
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ERNSTKVSPQDHMYTFIKLLANTSYVFKVRASTSAGEGDESTCHVSTLPETVPSVPTNIA
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       EGALFPNNEDSAQVLSSNQVSESQISARSLAPGKEYVFTISPVSGDPSSFEQVGEPETVV
Spur_Spur_PTPRB5.AA       DEGSVDVDGDELPVNITGVMTSIKILNLAAGKG-------YTVGITAISGDKRSENTTFL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             FSDVQSTSATLTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLT
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       TYTQPLSPQNLVVSDVGVEEVSLSWNLPAEVNFPIAYYEIDLVPNEPTFPIRINGTRDKW
Spur_Spur_PTPRB5.AA       FYTLPDPPQNLVISEIGEDTATLSWADPAEMNFDILEVVMTTMPATKTTILKLNTNTVEL
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             -------------------------------------------------------NWKDK
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ---------------------------------STLTAATAPNEVTDLQ-----------
Hsap_PTPRQ.AA             EETVYGLKKFRWYRFQVAASTNAGYGNASNWISTKTLPGPPDGPPENVH-----------
Spur_Spur_PTPRB2.AA       ------------------------------TTWRQRTFAARPNMIENL------------
Hsap_PTPRJ.AA             -------------------------------EPGRKSFCTDPASMASFD-----------
Cele_dep-1.AA             --------------------PQCPAATRTMRQLSFSTRQDKPAAVQDLK-----------
Spur_Spur_PTPRB3.AA       EIHDGLVSGGEYQAVMRSVINDVNGQVIYSEPLQSAFFLLEPTQPQRLSTPYVTTTELRV
Spur_Spur_PTPRB5.AA       TNLVPGQTYTVQLASVIRPDDALNQPEVIGEPQVSSPFLMKPASPSDIS-----------
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------VPVGETTLPTKPGPVDRLR-----------
Dmel_Ptp10D.AA            -------------------------RSSSPLSASFTTNEAVPGRVERFH-----------
Dmel_Ptp4E.AA             ----------FADVSVSTLMRSSAP-----ISASYQTLTAPPGKVDYFQ-----------
Hsap_PTPRO.AA             -----------------------------CCDSSTISFITAPVAPEITS-----------
Hsap_PTPRB.AA             DLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMSFAD-----------
Aque_Aque_PTPRB-1.AA      -----------------------------SPSVSNMTFEGVPSAPDPVI-----------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------ITQTNRTLPDKPSPVGNPQ-----------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       EWTLGNSNFTTFQVSFSKDSATILTTDTTEQSLLLTNLTVATVYDISIRTVVEGPQTNMI
Spur_Spur_PTPRB5.AA       ------------------------------------------------------------
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ----------------------NETQTKNSVMLWWKAPG---------------------
Hsap_PTPRQ.AA             ---------------------VVA-TSPFSISISWSEPAVITGPTCYLIDVKSVDNDEFN
Spur_Spur_PTPRB2.AA       ---------------------MIVTTSASSVNVVFNVPT---------------------
Hsap_PTPRJ.AA             ---------------------CEVVPKEPALVLKWTCPP---------------------
Cele_dep-1.AA             ----------------------VEPLNSYSVMLTWLPPA---------------------
Spur_Spur_PTPRB3.AA       KTSAAALIMAVTTKSKPPQNLMQDEVTSDSITVSWGAPLNVVNMYHIIVKDEDGADVADA
Spur_Spur_PTPRB5.AA       ----------------------VSNNELTRVTVTWQPSEGVVARYSYTYGLPGSTVTASE
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ---------------------LEPQIDHRQIRLAFLAPM---------------------
Dmel_Ptp10D.AA            ----------------------PTDVQPSEINFEWSLPS---------------------
Dmel_Ptp4E.AA             ---------------------PSD-VQPGEVTFEWSLEP---------------------
Hsap_PTPRO.AA             -----------------------VEYFNSLLYISWTYGD---------------------
Hsap_PTPRB.AA             -------------------------IANTSLAITWKGPP---------------------
Aque_Aque_PTPRB-1.AA      ----------------------VKRRNDTAIQVNWTRPA---------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ---------------------AEA-VDKNTITLTYESPL---------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       --------------------------MNYGILLEIA------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ISFIKSNEENKTIEIKDLEIFTRYSVVITAFTGN--------ISAAYVEGKSSAEMIVTT
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       TVPSSETSYTIENLNPYTKYIITVAARFNGLDSD--------AIEIEQTTFQGKPSVVRD
Spur_Spur_PTPRB5.AA       TTTTTDTSIQLSNLTPSTRYEFRLWAESDQTEGSETSSSDVVTVNIVTTVFFNVPSDPVS
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ----DWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWK
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             -----------------------------------DPHSQLYVYWVQWASKGHPRR--GQ
Hsap_PTPRQ.AA             LESAPKDPPNNMTFQ---KIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIH
Spur_Spur_PTPRB2.AA       -----------------------------------KPNGLITGYLISYNGMRNTAT---S
Hsap_PTPRJ.AA             --------------------------------------GANAGFELEVSSGAWNNA----
Cele_dep-1.AA             -----------------------------------LPNGILTHYAVNVTKIGSDET----
Spur_Spur_PTPRB3.AA       PVVAINSPNSVF----------------LTWTPPDSPNGILTGFVVEITGEDLTSR--KR
Spur_Spur_PTPRB5.AA       ALPVTTLPSMPSAVGGLTITKTGIVDAEVSWSSPLLPNGVIANYSLTIHISHDNGT-LSP
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       -----------------------------------LPNGVLEGYRVEYVGKRNGSR----
Dmel_Ptp10D.AA            ----------------------------------SEANGVIRQFSIAYTNINNLTD----
Dmel_Ptp4E.AA             ----------------------------------AEQHGPIDYFRITCQNADDAAD----
Hsap_PTPRO.AA             -------------------------------DTTDLSHSRMLHWMVVAEGKKKIKK----
Hsap_PTPRB.AA             TYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEV----
Aque_Aque_PTPRB-1.AA      -----------------------------------EPNGIILGYLIYYIGTKNNTGTEYS
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       -----------------------------------EPNGDITGYRISYIGTRD-------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       -----------------------------------ERHFVLVAFLILVRRVRVSTMLRHR
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             DPQANWVNQTSRTNETWYKVEALEPGTLYNFTVWAERNDVASS-----------------
Hsap_PTPRQ.AA             NLSIIQKTNTF----VIAMLEGLKGGHTYNISVYAVNSAGAGP--KVPMRITMDIKAPAR
Spur_Spur_PTPRB2.AA       SGNQFFSDIHPNDVRVEVPIASLDPGYVYQFSVQAVNGEGTSD--AVIGEVTLVAGGNGI
Hsap_PTPRJ.AA             --THLESCSSENGTEYRTEVTYLNFSTSYNISITTVSCGKMAA--PTRNTCTTGITDPPP
Cele_dep-1.AA             RTIDVGVSSNRSDHTVQVVIDELFGGHTYSFSVRAVTEAGFGENSPVVPTVSMPLMAPPV
Spur_Spur_PTPRB3.AA       REAGFTRTETYGVTVFSATIENLPTGCSYTFSIKAANSADQSD--AVIAGPLDLPHSAPP
Spur_Spur_PTPRB5.AA       YGDTVTISAVAEQTEYSQDVIGLAAGQYYVFSVYATNQVASSN--QRSTTRTLFAETAPP
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       --TCSSGQKYLPVVETSVIIEGLKGGCYYTFTVKARNEVGLGP--GASDSVLTAIGIPQV
Dmel_Ptp10D.AA            -----AGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFGP--EREYRQTMPILAPPR
Dmel_Ptp4E.AA             -----VSSYEFPVNATQGKIDGLVPGNHYIFRIQAKSALGYGA--EREHIQTMPILAPPV
Hsap_PTPRO.AA             ----------SVTRNVMTAILSLPPGDIYNLSVTACTERGSNT------SMLRLVKLEPA
Hsap_PTPRB.AA             -----EFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSE--VVEDSTITMIDRPPP
Aque_Aque_PTPRB-1.AA      NINVLIIINVTDPNTLSYLITNLLADTQYFINVTAYTSAGLGAVGDGDSILLPTGRPPTV
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       --------------------------------IIAVNDGGFES-DPALTEPVETPQEEPS
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       NQAPLQGEDEAPKTTPSPIIARYVSKEYAPLPL---------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ---------------------------TQSLCASTYPDTVTITSCVSTSAGYGVNLIWSC
Hsap_PTPRQ.AA             PKTKPTPIYDAT-GKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKW
Spur_Spur_PTPRB2.AA       NAQGATAS---------SSATTITIVINDNLFSDVNGAVIALQVFVAEEHASNTDRTISD
Hsap_PTPRJ.AA             PDGSPNIT----------SVSHNSVKVKFSGFEASHGPIKAYAVILTTGEAGHPSADVLK
Cele_dep-1.AA             PTVAPMIM------KESVGSHNMIVRFPTTMFDNRNGEIKQFAIIVSETTADESINRWIE
Spur_Spur_PTPRB3.AA       TPPADRVV-----RLVSHTGTTMSVSFDSSIFSDVYGPVTRYALLVAQSSPDTIPSTPSD
Spur_Spur_PTPRB5.AA       SPPRGATP------SLVSRGSTITITF-FNLFDTAFGRIVRFAIIVQERVDGGTVVITAK
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       PDARPLPP-----PSKTIRSRNFVVNFDPSIFDDVNGEITHVIVIVAQSSDTRRKRSVAA
Dmel_Ptp10D.AA            PATQVVPT------EVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMP
Dmel_Ptp4E.AA             PEPSVTPL------EVSRTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDVGKNASGLEMP
Hsap_PTPRO.AA             PPKSLFAV--------------NKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEP
Hsap_PTPRB.AA             PPPHIRVN----EKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQ
Aque_Aque_PTPRB-1.AA      PPNVTIGTPPTGGTSDPTTATTIRIEVTIPEELNANGPLTRIRILIRIFLSRNDTISTWY
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       PVPEDYPYEANT-VFSETSTTSFAVVLPDDLFSHENGELLTFAVIITIDDNDPTVSSTEL
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       -------------LEVFIYAAFIITVFSRAFFAVYEASKEYKDVLYSFNFEEGWYIFWHK
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------PQGGYEAFELEVGGQRGSQDRSSC
Hsap_PTPRQ.AA             ------YDAYFNKARPYFTNEGFPNP-P----CTEGKTKFSGNEEIYIIGADNACMIPGN
Spur_Spur_PTPRB2.AA       PPRRYQQVRDLLFRTAYVTSPLFAPTPF----GGRRKRQIADTLTSYTIGSEREC---VS
Hsap_PTPRJ.AA             ------YTYEDFKKGASDTYVTYLIR-T----EEKGRSQSLSEVLKYEIDVGNES----T
Cele_dep-1.AA             ---SDNGTYTWQQVQRFDVWPSYVAKLQ----DIQKVKQDVDVSIFEELGEDETC-LEVR
Spur_Spur_PTPRB3.AA       ----------PAINWQVGSGQPYQTT-L----LTYAPFTNGNTRGFYTVGANNSC--TQD
Spur_Spur_PTPRB5.AA       --RQTTSSLTWAEARRTRPVPSYQTT-P----DDYNPFADGAGVTTFRVGSQSCD--PDD
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------TTPTTPTITKIDIGTEECS--YET
Dmel_Ptp10D.AA            SWLDVQSYSVWLPYQAIDPYYPFENR----------------SVEDFTIGTENCD---NH
Dmel_Ptp4E.AA             SWQDVQAYTVWLPYQAIEPYNPFLTS--------NGSRKSSLEAEHFTIGTANCD---KH
Hsap_PTPRO.AA             --------------------------------------------------------VAVS
Hsap_PTPRB.AA             HPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLG-GKCD---PT
Aque_Aque_PTPRB-1.AA      ----------ESQKFPNSVAPPWQATQLPLNQGNRRKRQAGGETVAETIGTNNSC---GP
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ----------------------YPPS-F----GSNRKRRATEPSATVVIGNGTCA---GS
Spur_Spur_PTPRB9.AA       ---TYAARAENAYITAIEIPYPYSPS-F----GSNRRRRATDPPGTVVIGDGTCA---GS
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ----------------------------------------DKDIGDFEWT-------HWR
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             GEAVSVLGLGPARSYPATITTIWD------------GMKVVSH-----SVVCHTESAGVI
Hsap_PTPRQ.AA             EDKICNGPLKPKKQYLFKFRATNI-----MGQ----FTDSDYSDPVKTLGEGLSERTVEI
Spur_Spur_PTPRB2.AA       EDSICNGPLEPLTSYRVLVRAYT------DGG----FADSPWS-----EPISTRALDSWF
Hsap_PTPRJ.AA             TLGYYNGKLEPLGSYRACVAGFTNITFHPQNKGLIDGAESYVSFSRYSDAVSLPQDPGVI
Cele_dep-1.AA             ADRICNGPLRSASKYRVRIRLFTSPTL---------FTDSPPSQVMTTGSATPAIPLLTV
Spur_Spur_PTPRB3.AA       SVGYCNGPVVPLTDYRFALRAYGS-----DGK----FTDSAWS-----PLYNSGINTTWY
Spur_Spur_PTPRB5.AA       LTAYCNGALYPGTSYRFAIRAYGV-----DGK----FVDTEFS-----SPFRTDPDRGIF
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       KNVYCNGPLIQGRSYVYRFRGIS------PGG----YADTKNS-----LPVSLPMSPHGV
Dmel_Ptp10D.AA            KIGYCNGPLKSGTTYRVKVRAFTG-----ADK----FTDTAYS-----FPIQTDQDNTSL
Dmel_Ptp4E.AA             QAGYCNGPLRAGTTYRIKIRAFTD-----EDK----FTDTVYS-----SPITTERSDTVI
Hsap_PTPRO.AA             SHVVTISSLLPATAYNCSVTSFS-------------HDSPSVPTFIAVSTMVTEMNPNVV
Hsap_PTPRB.AA             QQKFCDGPLKPHTAYRISIRAFTQLFDEDLKE----FTKPLYSDTFFSLPITTESEPLFG
Aque_Aque_PTPRB-1.AA      NDIVCNGPLKPGTQYQFKYRVYNSDDDDS-------YVESQYSGPIRTDPIAEENNTGTT
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       PKEYCNRGLDDDTEYYYAFRAYNG-----MGN----VTSSTFG-----------------
Spur_Spur_PTPRB9.AA       QNEYCNGDLDDNTEYYYAFRAYNG-----MGN----VTSSTFG------PVKTVKDNTAG
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       NIFFSPGVLVVMVLHAALGRIVG-------------YVYPKYR-------------TSFL
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             AGAFVGILLFLILVGLLIFFLKR-------------------------------------
Hsap_PTPRQ.AA             ILSVTLCILSIILLGTAIFAFAR------------------------------------I
Spur_Spur_PTPRB2.AA       TIPIISYGVVIFFILIFLLLCCL-------------------------------------
Hsap_PTPRJ.AA             CGAVFGCIFGALVIVTVGGFIFW-------------------------------------
Cele_dep-1.AA             VAVLIVIAFVGIVGTIFLFFWNRTKKARLAAAAFKNGPSKEKESQWEALKMMMAERAADC
Spur_Spur_PTPRB3.AA       AAAVVSIIIITLVLLLVMLLISR------------------------------------Q
Spur_Spur_PTPRB5.AA       VIPAIVLAIMVVIILIIFMAMGF------------------------------------G
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       IIGISTALFSLLVVVIILSIVII-------------------------------------
Dmel_Ptp10D.AA            IVAITVPLTIILVLLVTLLFYKR-------------------------------------
Dmel_Ptp4E.AA             VAATVSAVLLVAMVLVVVYCQHR------------------------------------C
Hsap_PTPRO.AA             VISVLAILSTLLIGLLLVTLIIL-------------------------------------
Hsap_PTPRB.AA             AIEGVSAGLFLIGMLVAVVALLI------------------------------------C
Aque_Aque_PTPRB-1.AA      IVIAVVVVLLVIILLIAILVIVV-------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       IAAGVSVSLIIIIVAVVVVVVFL------------------------------------K
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       LCFAVVSIYLFVGLRLLLYFLC--------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             RQKQKEGGTYSPQDAEIIDTKLKLD-----------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             LAKLGLDATTPPPSSTTSSNSPTSTSTTMTDCGSNPHLGAPNAGGHRRTRSLRERTGVEH
Spur_Spur_PTPRB3.AA       CCGEARSSALYERGNGQHLPLVNAAYPSAHNQDSMHKTPLPEDAFIRMGPIPVRENA---
Spur_Spur_PTPRB5.AA       CCGKPDDGMYSDDSNGYGNDYSNGNGYSNGNGNGIMKRALINDGVNTYAYQQPQIMEHSF
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            -----------------------------------------------------------R
Dmel_Ptp4E.AA             QL----------------------------------------------------------
Hsap_PTPRO.AA             ------------RKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLW
Hsap_PTPRB.AA             RQKVSHGRERPSA-----------------------------------------------
Aque_Aque_PTPRB-1.AA      ----------------IIVLKRRKRKAYSFAASFNGKEELITAGEGKGATLSKAIQLTPT
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       RRQPKEPSPRPSLEGRENQG----------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             --------RNKKKQQKPELRDLVFSSPGDIPAEDFADHVRKNERDSN----CGFADKYQQ
Hsap_PTPRQ.AA             --QLITVADLELKDERLTRLLSYRKSIKPISKKSFLQHVEELCTNNN----LKFQEEFSE
Spur_Spur_PTPRB2.AA       --------SSGRHGRKKVKSSPGPRKARGFHSPQQESRFNDNHNNSS----NRHPRHSKA
Hsap_PTPRJ.AA             -----RKKRKDAKNNEVSFSQIKPKKSKLIRVENFEAYFKKQQADSN----CGFAEEYED
Cele_dep-1.AA             RLERLSSGPVHRTPLYTVVTGANTNKSRPVRIEDFADHVRLMSADSD----FRFSEEYDM
Spur_Spur_PTPRB3.AA       --YVSMRDDRPKAPLPATLPRSAPPLTNPVQMRKFPDHVNRMSAGNN----TGFVEEYNS
Spur_Spur_PTPRB5.AA       TNIPDYSTIPPNRGTTAQVHQPSTTHTRPTKKNMFAQHVAKMSARNN----AGFSDEYNN
Spur_Spur_PTPRB7.AA       -----------------------------------------MSARNN----DGFSDEYNS
Spur_Spur_PTPRB8.AA       --------------------------VRKFRLDGRGRYLPANMKDVE----LT-----RA
Dmel_Ptp10D.AA            RNNCRKTTKDSRANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSD----FRFSEEFEE
Dmel_Ptp4E.AA             --IRRASKLARMQDELAALPEGYITPNRPVHVKDFSEHYRIMSADSD----FRFSEEFEE
Hsap_PTPRO.AA             TDYLLAFYINPWSKN----GLKKRKLTNPVQLDDFDAYIKDMAKDSD----YKFSLQFEE
Hsap_PTPRB.AA             --RLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSN----YLLSKEYEE
Aque_Aque_PTPRB-1.AA      DPTIVPLTENTIVNPTATASVKATPNSRKVYLRDFPSYVEDMLNDAG----FKFSEEYEK
Aque_Aque_PTPRB-2.AA      -----------------------------------------------------------K
Spur_Spur_PTPRB6.AA       ----------------------------PVK----------------------TVLKAEK
Spur_Spur_PTPRB9.AA       --YDGPDHEMRPTRRKTGGSMHRKSHSKPIVLNKFEGHYGRMKADSD----FRFTEEYDE
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       --HSLLMYTVTCTASMSTVWCIVLMQIASINLDFFLRFQRYIFTDEDDLNMMVFTLAMCT
Spur_Spur_PTPRB4.AA       ---------------------------RPVLLANIETHYDWLKADSE----HRLMEEYDD


Hsap_PTPRH.AA             LSLVG-HSQSQMVASA-SENNAKN--RYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPG
Hsap_PTPRQ.AA             LPKFL-QDLSSTDADL-PWNRAKN--RFPNIKPYNNNRVKLIADASVPGSDYINASYISG
Spur_Spur_PTPRB2.AA       PPLI--LSRPILSSQF-PL-------HYNEMVADKQHKFTME---------------FDG
Hsap_PTPRJ.AA             LKLVG-ISQPKYAAEL-AENRGKN--RYNNVLPYDISRVKL-SVQTHSTDDYINANYMPG
Cele_dep-1.AA             MRNVG-VGQSVAASEL-PINRPKN--RFTNIPSYDHSRVKLSNPNNIEGGDYINANYVPG
Spur_Spur_PTPRB3.AA       LSNVG-RDKSTDASRL-AVNATKN--RYRNILPFDETAVHLQDLEEGQTSDYINANYIQG
Spur_Spur_PTPRB5.AA       LPAME-KTRAVTAARQ-ARNDDKN--RYRNILPYDYTRVQL---KGVAGTDYINASYIKD
Spur_Spur_PTPRB7.AA       LPAME-KIRAVTVARN-ARNDDKN--RFRNILPYDYNRVQL---KGEVGNDYINASYIAD
Spur_Spur_PTPRB8.AA       IRKVG-RKMTTNTAVS-PANVGKN--RYTNILPYDRTRVKLSPVDDEEGSDYINSNYIPG
Dmel_Ptp10D.AA            LKHVG-RDQPCTFADL-PCNRPKN--RFTNILPYDHSRFKLQPVDDDEGSDYINANYVPG
Dmel_Ptp4E.AA             LKHVG-RDQACSFANL-PCNRPKN--RFTNILPYDHSRFKLQPVDDDDGSDYINANYMPG
Hsap_PTPRO.AA             LKLIG-LDIPHFAADL-PLNRCKN--RYTNILPYDFSRVRLVSMNEEEGADYINANYIPG
Hsap_PTPRB.AA             LKDVG-RNQSCDIALL-PENRGKN--RYNNILPYDATRVKLSNVDDDPCSDYINASYIPG
Aque_Aque_PTPRB-1.AA      VSAVG-LDHSKDASLL-PENRAKN--RYTNILAYDHSRVKLESIDDEPGSDYINANYIPG
Aque_Aque_PTPRB-2.AA      VSAVG-LDHSKDASLL-PENRAKN--RYTNILAYDHSRVKLESIDDEPGSDYINANYIPG
Spur_Spur_PTPRB6.AA       IKAMMDLIMKCDQHEEKPAAQCTG-----KVILNEHSRVKLAALADDSDTDYINANYIPG
Spur_Spur_PTPRB9.AA       IRLVG-KDQAIVSALE-MVNRAKN--RFTNILPYEHSRVKLAALADDSDTDYINANYIPG
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       LRHISFAYEFCHFHST-PVARRPNEKQYWGILDFLLYIYYLPLFFGGPVLTY--------
Spur_Spur_PTPRB4.AA       IQAVGSIVRMDQATNA-EVNKTKN--RFNKILPYEHSRVKLMALKGKSETDYINANYIPG


Hsap_PTPRH.AA             LWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP-LDSQPC-
Hsap_PTPRQ.AA             YLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWP-EDNKPVT
Spur_Spur_PTPRB2.AA       FNKPQEYIATQGPMSNTVHEFWRMVWEKECPAIVMLVRCIEGGKEKCDKYWP-INSDPT-
Hsap_PTPRJ.AA             YHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWP--SKQAQ-
Cele_dep-1.AA             FSSRREFIAAQGPLPTTRDHFWQMTWEQQCPAIIALTKCVEKGRDKCHQYWPDHENVPV-
Spur_Spur_PTPRB3.AA       LHSMKEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWP-DDDTPV-
Spur_Spur_PTPRB5.AA       DHGQKKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWP-AGEEPQ-
Spur_Spur_PTPRB7.AA       DQGNRKYIATQGPLPNTIDHFWEMVWETKASTIVMMTALVEGGKTKCEHYWP-TGQKPH-
Spur_Spur_PTPRB8.AA       FTSPREYIACQGPLPGTTDDMWRMIWEQNVTTVVMVTQLVEKGKVKCDQYWP-DDHMPV-
Dmel_Ptp10D.AA            HNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-NDTVPV-
Dmel_Ptp4E.AA             HNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-VDRVAM-
Hsap_PTPRO.AA             YNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPI-
Hsap_PTPRB.AA             NNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWP-ADQDSL-
Aque_Aque_PTPRB-1.AA      YRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWP--GAQPE-
Aque_Aque_PTPRB-2.AA      YRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWP--GAQPE-
Spur_Spur_PTPRB6.AA       YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR--------------
Spur_Spur_PTPRB9.AA       YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWP-ADYNPV-
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       DKFSRQWKHILKELFRYI--FWAMFIETVLHFL----------------YFPAFHQRPF-
Spur_Spur_PTPRB4.AA       FNSPREYIACQGPLPETTNDMWRMIWEKKSTIIVMMTKTVEGGKDKCHQYWPKKKGRSDT


Hsap_PTPRH.AA             THGHLRVTLVGEEVMENWTVRELLLLQVEEQKT---------------------------
Hsap_PTPRQ.AA             VFGDIVITKLMEDVQIDWTIRDLKIERHGD----C-------------------------
Spur_Spur_PTPRB2.AA       VFGKVIVTKLAEHTHDTWAVRDFRLKVGSEE-----------------------------
Hsap_PTPRJ.AA             DYGDITVAMTSEIVLPEWTIRDFTVKNIQTSES---------------------------
Cele_dep-1.AA             LYGDIEVTIVAEKEFDEFVIRDIRLEKSGPDGRVT-------------------------
Spur_Spur_PTPRB3.AA       NYGSVTVTMTHTQEMEQWTVRSFLLEKGMQ----Q-------------------------
Spur_Spur_PTPRB5.AA       LHGNVTVTLVGSNQTDNFIERTLLLEKEGT----E-------------------------
Spur_Spur_PTPRB7.AA       LHGNVTVTLVGSKQTEHFIQRTLLIGKKGT----E-------------------------
Spur_Spur_PTPRB8.AA       LYGDIQVTMNQTFEENDWNIKEFAVQLRDQ----R-------------------------
Dmel_Ptp10D.AA            FYGDIKVQILNDSHYADWVMTEFMLCRGSEQ-----------------------------
Dmel_Ptp4E.AA             FYGDIKVQLIIDTHYHDWSISEFMVSRNCES-----------------------------
Hsap_PTPRO.AA             AYGDITVEMISEEEQDDWACRHFRINYADEM-----------------------------
Hsap_PTPRB.AA             YYGDLILQMLSESVLPEWTIREFKICGEEQLDAH--------------------------
Aque_Aque_PTPRB-1.AA      VYGEINVDMLSETEKSDWIVRKFKITKEKRS-----------------------------
Aque_Aque_PTPRB-2.AA      VYGEINVDMLSETEKSDWIVRKFKITKEKRS-----------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       TYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRT
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       LLNSMSL----------WAVGGLALCQ---------------------------------
Spur_Spur_PTPRB4.AA       YGGSLEVSLQSELDYEHWITRTFMLQKNKM----K-------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       ------------------------------------------------------------
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             ------------------------------------------------------------
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       VREAIQKTASDRPIVAHCSAGAIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFS
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             -------LSVRQFHYQAWPDHGVP--SSPDTLLAFWRMLRQWLDQT-MEGGPPIVHCSAG
Hsap_PTPRQ.AA             -------MTVRQCNFTAWPEHGVP--ENSAPLIHFVKLVRASRAHD---TTPMIVHCSAG
Spur_Spur_PTPRB2.AA       -------RLIRQYHFISWPTHSTP--RVSRPTLNFVKNIREELESP-KLSGPLVVHCGAG
Hsap_PTPRJ.AA             -------HPLRQFHFTSWPDHGVP--DTTDLLINFRYLVRDYMKQS-PPESPILVHCSAG
Cele_dep-1.AA             -------RFVRHWHYMAWPDFGAP--SHPNGIIQFSRMFRHHLPHS-PHNAPTIVHCSAG
Spur_Spur_PTPRB3.AA       -------FETHQYAFKGWVDHDVP--NNARPMIEFIRTIDVAHDAN---LGPITVHCSAG
Spur_Spur_PTPRB5.AA       -------RTVTHYQYLAWTDHGVP--ESTAPLVGLLRQVKVTNQEDGAATGPIVVHCSAG
Spur_Spur_PTPRB7.AA       -------LTVTHYQYLAWTDHGVP--ASTAPLVALLYQVKMTSQEDGALTGPIIVHCSAG
Spur_Spur_PTPRB8.AA       -------RYVRHWNFLSWPDHGVP--ESSQALLAFIRRIRSTKPPS---SAPVAVHC---
Dmel_Ptp10D.AA            -------RILRHFHFTTWPDFGVP--NPPQTLVRFVRAFRDRIGAE---QRPIVVHCSAG
Dmel_Ptp4E.AA             -------RIMRHFHFTTWPDFGVP--EPPQSLVRFVRAFRDVIGTD---MRPIIVHCSAG
Hsap_PTPRO.AA             -------QDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKS---KGPMIIHCSAG
Hsap_PTPRB.AA             -------RLIRHFHYTVWPDHGVP--ETTQSLIQFVRTVRDYINRS-PGAGPTVVHCSAG
Aque_Aque_PTPRB-1.AA      -------RTITHYQFVSWPDHGVP--DEAGPALDFVREVHEVASSA---FGPVIVHCSAG
Aque_Aque_PTPRB-2.AA      -------RTITHYQFVSWPDHGVP--DEAGPALDFVREVHEVASSA---FGPVIVHCSAG
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ISQGDEIRKLTQYHFMSWPDHGVP--DKTWTMLDFVRTVREAIQKT-ASDRPIVAHCSAG
Spur_Spur_PTPRB10.AA      ----------------------------------------------------------AG
Spur_Spur_PTPRB1.AA       -------LLFFQMKYTVM--YGLP-------------RVHAMFDHI---NAPLPPVCILG
Spur_Spur_PTPRB4.AA       -------REVIQLQFTSWPDHGVP--EQTKPMLDFVKNVRERIRNK-CVIKPVIVHCSAG


Hsap_PTPRH.AA             VGRTGTLIALDVLLRQLQSE---GLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
Hsap_PTPRQ.AA             VGRTGVFIALDHLTQHINDH---DFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLL
Spur_Spur_PTPRB2.AA       IGRTGVFIALDILLQELKAD--ERTVDVFAVVAKMRRERCSLVQSLVQYIFLHRALADFL
Hsap_PTPRJ.AA             VGRTGTFIAIDRLIYQIENE---NTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIV
Cele_dep-1.AA             VGRSGTFISIDRLLQSSSFG---DPIDVFGTVCEMRYERCQMVQNEQQYIFIHYCILQVL
Spur_Spur_PTPRB3.AA       IGRTGVFIALHKLIKQVETSKPNDYIDVCGTVARMREQRFNMVQTVKQYMFIHQCLLLLM
Spur_Spur_PTPRB5.AA       VGRTGTFIAADMLMDAIQRSTATDYIDVAGTIAKIREQRALLVQTLYQYIYLHRTVLSLI
Spur_Spur_PTPRB7.AA       IGRTGTFIAADMLMNAIQRSTATDYIDIAGTVAKLREQRTSLVQTLVRDK----------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            VGRSGTFITLDRILQQINTS---DYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVL
Dmel_Ptp4E.AA             VGRSGTFIALDRILQHIHKS---DYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
Hsap_PTPRO.AA             VGRTGTFIALDRLLQHIRDH---EFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMW
Hsap_PTPRB.AA             VGRTGTFIALDRILQQLDSK---DSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL
Aque_Aque_PTPRB-1.AA      VGRTGTFIALGTLLQHIKDH---DWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC
Aque_Aque_PTPRB-2.AA      VGRTGTFIALGTLLQHIKDH---DWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       VGRTGTYIALDRLMQAMQEN---DYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
Spur_Spur_PTPRB10.AA      VGRTGTFIVLDNILQHMEQY---DFVDVMGVVCGMRMHRNFMVQTEQQYVFIHRCLMDVI
Spur_Spur_PTPRB1.AA       M----------YLFQDFWRY------------FDRGLHSLLVSKYGKDFM----CNKFYY
Spur_Spur_PTPRB4.AA       VGRTGTYIALDRLTQHMEDN---DFVDVCGVVCEMRMHRNYLVQTETQYIFIHDCLMDYF


Hsap_PTPRH.AA             QQSAQAPAEKEVPYEDVE------------------------------------------
Hsap_PTPRQ.AA             SNKGSNQPICFVNYSALQ------------------------------------------
Spur_Spur_PTPRB2.AA       QGQGHGVEVSSIERSDAG------------------------------------------
Hsap_PTPRJ.AA             RSQKDSKVDLIYQNTTAM------------------------------------------
Cele_dep-1.AA             QGSSPSPTSTSTGAHHNA------------------------------------------
Spur_Spur_PTPRB3.AA       R-----------------------------------------------------------
Spur_Spur_PTPRB5.AA       EEQ---------------------------------------------------------
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            EGKENIVGPAREMHDNEG------------------------------------------
Dmel_Ptp4E.AA             EGKEHLLADSLELHANDGYEVTKIYLERQPQTKMGTLPIRASLAMAEKLDADLMTNKDED
Hsap_PTPRO.AA             MKKKQQFCISDVIYENVSKS----------------------------------------
Hsap_PTPRB.AA             RARKLRSEQENPLFPIYE------------------------------------------
Aque_Aque_PTPRB-1.AA      KSSMSKFGGGIKVLPSFP------------------------------------------
Aque_Aque_PTPRB-2.AA      KSSMSKFGGGIKVLPSFP------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       RRGEEEDTGESIYVNLPS------------------------------------------
Spur_Spur_PTPRB10.AA      EERGLAPVPMMSGSLP--------------------------------------------
Spur_Spur_PTPRB1.AA       RT----------------------------------------------------------
Spur_Spur_PTPRB4.AA       CSGVAP------------------------------------------------------


Hsap_PTPRH.AA             ------------------------------------------------------------
Hsap_PTPRQ.AA             ------------------------------------------------------------
Spur_Spur_PTPRB2.AA       ------------------------------------------------------------
Hsap_PTPRJ.AA             ------------------------------------------------------------
Cele_dep-1.AA             ------------------------------------------------------------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       ------------------------------------------------------------
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            ------------------------------------------------------------
Dmel_Ptp4E.AA             EDQEQQQQQQLQLATEVKPKGSNDDEEDEEDDDDDDDDQQPLNNETTATLSSASCSSSTH
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------------------------
Aque_Aque_PTPRB-1.AA      ------------------------------------------------------------
Aque_Aque_PTPRB-2.AA      ------------------------------------------------------------
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       ------------------------------------------------------------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             ---------------------------------------------NLIYENVAAIQAHKL
Hsap_PTPRQ.AA             --------------------------------KMDSLDAMEGDVELEWEETTM-------
Spur_Spur_PTPRB2.AA       --------------------------------------SIQSDEIEQMSNTSL-------
Hsap_PTPRJ.AA             ------------------------------------------TIYENLAPVTTFGKTNGY
Cele_dep-1.AA             ---------------------------------------GFVQDGQMIVESGF-------
Spur_Spur_PTPRB3.AA       ------------------------------------------------------------
Spur_Spur_PTPRB5.AA       ------------------------------------------------------------
Spur_Spur_PTPRB7.AA       ------------------------------------------------------------
Spur_Spur_PTPRB8.AA       ------------------------------------------------------------
Dmel_Ptp10D.AA            -----------------------------------------YEDDEGIAESGM-------
Dmel_Ptp4E.AA             DVHVVLQEAIEKPKQEQERICAGTQSHADTESDNTDSDDDDEDGDGKVAKDGAVADEDGW
Hsap_PTPRO.AA             ------------------------------------------------------------
Hsap_PTPRB.AA             ------------------------------------------NVNPEYHRDPVYSRH---
Aque_Aque_PTPRB-1.AA      --------------------IYSNIGPASQLSDFYGDMLSEEASYQYQKTSGNGKTYDES
Aque_Aque_PTPRB-2.AA      --------------------IYSNFGPASQLSDFYGDMLSEEASYQYQKTSGNGKTYDES
Spur_Spur_PTPRB6.AA       ------------------------------------------------------------
Spur_Spur_PTPRB9.AA       -----------------------------------NGFKDPDDVNKNLLDQAV-------
Spur_Spur_PTPRB10.AA      ------------------------------------------------------------
Spur_Spur_PTPRB1.AA       ------------------------------------------------------------
Spur_Spur_PTPRB4.AA       ------------------------------------------------------------


Hsap_PTPRH.AA             EV
Hsap_PTPRQ.AA             --
Spur_Spur_PTPRB2.AA       --
Hsap_PTPRJ.AA             IA
Cele_dep-1.AA             --
Spur_Spur_PTPRB3.AA       --
Spur_Spur_PTPRB5.AA       --
Spur_Spur_PTPRB7.AA       --
Spur_Spur_PTPRB8.AA       --
Dmel_Ptp10D.AA            --
Dmel_Ptp4E.AA             WY
Hsap_PTPRO.AA             --
Hsap_PTPRB.AA             --
Aque_Aque_PTPRB-1.AA      TF
Aque_Aque_PTPRB-2.AA      TF
Spur_Spur_PTPRB6.AA       --
Spur_Spur_PTPRB9.AA       --
Spur_Spur_PTPRB10.AA      --
Spur_Spur_PTPRB1.AA       --
Spur_Spur_PTPRB4.AA       --