Mbre_mbre_RNGTT.AA               ------------------------------MAAQYNPRAVPERWLPCPRFG-KLIDAGEG
Cele_cel-1.AA                    -------------------------MATRGPTPDKARMGLPDRWLHCPKTG-TLIN---N
Aque_aque_RNGTT-A.AA             MSGQSYTRRSTWPLLDPSHSIIDGMMINPSRRRSVHTQSIPRSWRHCPKEG-SLIA---N
Aque_aque_RNGTT-B.AA             ----------------------------------MHTMSVPPRWRHCPRKG-KVIA---G
Dmel_mRNA-capping-enzyme.AA      -------------------------MALTNRDRERGSGPLPNRWLYCPRKSDTIIA---E
Nvec_nvec_RNGTT.AA               -------------------------------------MAIPPRWLNCPRKS-QVIA---D
Hsap_RNGTT.AA                    ----------------------------------MAHNKIPPRWLNCPRRG-QPVA---G
Spur_spur_RNGTT.AA               ------------------------------------MLAVPERWLNCPRKG-TLIA---G
                                                                        :*  *  **. .   :

Mbre_mbre_RNGTT.AA               HFWPFKTPLGRRYMDDVPIER-AWTPEMAKARYK----DELRFVINLTKTTRYYEAEEFG
Cele_cel-1.AA                    LFFPFKTPLCKMYDNQIAERRYQFHPAEVFSHPHLH-GKKIGLWIDLTNTDRYYFREEVT
Aque_aque_RNGTT-A.AA             KFLPFKTPLSSQYDKDLSEKE-RFPPSVLTSYRDT---YRIGLVIDLTNTSRYYDKREL-
Aque_aque_RNGTT-B.AA             KFFPFKTPLSSEYDKDLAEGN-RFPLSMLIAFTECIPGHRMGLVIDLTKTSRYYDKRELL
Dmel_mRNA-capping-enzyme.AA      RFLAFKTPLSNNFHDKMPIEC-TFQPEMLFEYCKTL-KVKLGLWVDLTNTKRFYDRSAVE
Nvec_nvec_RNGTT.AA               RFFAFKTPLSSRYDDQIPEAN-RFQLPMLCSYFQTL-KVKVGLIIDLTNTNRFYDKNELE
Hsap_RNGTT.AA                    RFLPLKTMLGPRYDSQVAEEN-RFHPSMLSNYLKSL-KVKMGLLVDLTNTSRFYDRNDIE
Spur_spur_RNGTT.AA               KFLPFKTPLGPKYNDSIPEEN-RFDTSMLFAYMNSR-QVKLGWVFDLTNTNRFYDKDEIE
                                  * .:** *   : ..:.     :                :   .:**:* *:*    .

Mbre_mbre_RNGTT.AA               --NDVHTQQIQCAGHGERPTPEQVKVFIHVCKTFWQKQPGCTIGVHCTHGFNRTGFMICC
Cele_cel-1.AA                    E-HECIYHKMKMAGRGVSPTQEDTDNFIKLVQEFHKKYPDRVVGVHCTHGFNRTGFLIAA
Aque_aque_RNGTT-A.AA             ---------LQC-----APDVEKVKEFQMVCGEFFKDHPYGVVGVHCTHGFNRTGFLIVS
Aque_aque_RNGTT-B.AA             K-CGIGHHKITCEGYGAAPNAEQVKEFQTLCVNFFKDHPDDIIGVHCTHGFNRTGFLIVS
Dmel_mRNA-capping-enzyme.AA      E-LGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFDVIAVHCTHGFNRTGFLIVC
Nvec_nvec_RNGTT.AA               RLTGIKHVKLQCRGHGETPSPDQTQLFINICCRYWDKNPGELIGVHCTHGFNRTGFLIIS
Hsap_RNGTT.AA                    K-EGIKYIKLQCKGHGECPTTENTETFIRLCERFNERNPPELIGVHCTHGFNRTGFLICA
Spur_spur_RNGTT.AA               K-NGARHIKLPCRGRGECPSKEQTSLFIQMCST-NCKNPDQIIGVHCTHGYNRTGFLICA
                                          :        *  :..  *  :        *   :.******:*****:* .

Mbre_mbre_RNGTT.AA               YLIEEMDCAVEDALQLFAKSRDPGIYKYGKATFFFFFSFFQLRPSLFLMTCHANFTLPFD
Cele_cel-1.AA                    YLFQVEEYGLDAAIGEFAENRQKGIYK---------------------------------
Aque_aque_RNGTT-A.AA             YLIDVECWDLEAAVATFSVARPPGIYK---------------------------------
Aque_aque_RNGTT-B.AA             YLIDVECWDLESAVATFSMARPPGIYK---------------------------------
Dmel_mRNA-capping-enzyme.AA      YLVERLDCSVSAALAIFASARPPGIYK---------------------------------
Nvec_nvec_RNGTT.AA               YLVEKEDWSIEAAVECFTKCRPPGIYK---------------------------------
Hsap_RNGTT.AA                    FLVEKMDWSIEAAVATFAQARPPGIYK---------------------------------
Spur_spur_RNGTT.AA               YLVETLDWSVDAAVSLFAQGRPPGIYK---------------------------------
                                 :*.:     :. *:  *:  *  ****

Mbre_mbre_RNGTT.AA               PQLRRPDYVEDLLQRY-HGDAPELIPRT-RPAWCAPNGPARAALQDAIDALHLKNAADIT
Cele_cel-1.AA                    -----QDYIDDLFARY-DPTEDDKILAPEKPDWEREMS--------------------IG
Aque_aque_RNGTT-A.AA             -----EHYLHELAGRYADGDIGSIITPP-LPDWC--------------------------
Aque_aque_RNGTT-B.AA             -----EHYLHELAGRYADGDIGSIVAPP-LPEWCFEED----------------------
Dmel_mRNA-capping-enzyme.AA      -----QDYINELYKRY--EDTNAAPAAPEQPNWCLDYDDGNGDGFVQDNSSSTSQQAGEQ
Nvec_nvec_RNGTT.AA               -----QEYLNELSRRY--GDSADPPSAPELPDWCYEDE-------------------GIS
Hsap_RNGTT.AA                    -----GDYLKELFRRY--GDIEEAPPPPLLPDWCFEDD----------------------
Spur_spur_RNGTT.AA               -----GDYIQELFDRY--GDVSEAPPPPDLPDWCVGAD----------------------
                                        *: :*  **           .  * *

Mbre_mbre_RNGTT.AA               PEVVQAVNEGCLRALEENKISEEPLPLEPALEKLNFADSFVKISDPQTVVEALKQVLADA
Cele_cel-1.AA                    MS---------------------------------------------------TQIDNGR
Aque_aque_RNGTT-A.AA             -----------------------------------------------------DDVEREK
Aque_aque_RNGTT-B.AA             -----------------------------------------------------EVDSGGE
Dmel_mRNA-capping-enzyme.AA      DD---------------------------------------------------DAEEVEG
Nvec_nvec_RNGTT.AA               DK---------------------------------------------------DEEDGEE
Hsap_RNGTT.AA                    -----------------------------------------------------EDEDEDE
Spur_spur_RNGTT.AA               -----------------------------------------------------DRDDDEI


Mbre_mbre_RNGTT.AA               PAAESPSAAEPPDHTASNDESEQALPSPCQFSLS--AVATTVVSA-PHLGPLRRKVRTLV
Cele_cel-1.AA                    PSTSQQIPATNGNNNQNGNQLSGGGDNSKLFMDGL-IRGVKVCEDEGKKSMLQAKIKNLC
Aque_aque_RNGTT-A.AA             E-------------------------KSAQFAVP--LHGVELVLG-PTREEVQIACQEAL
Aque_aque_RNGTT-B.AA             EGGGGK--GEEGQDRKGKKRKIEQNNDSAQFAVP--LHGVELVLG-STREEVQIACQEAL
Dmel_mRNA-capping-enzyme.AA      EDAGGDCDASTSDGQPRKKRRREMIIKNATFMAG--VPGVRQVSDQPRLGDLQRKVQDWC
Nvec_nvec_RNGTT.AA               EDSNN---AGPGNRRKKRRKAPGFPLKAAKFVDG--VDGVEVVPS-PKCEEIQDMCQEMC
Hsap_RNGTT.AA                    DGKKE---SEPGSSASFGKRRKERLKLGAIFLEGVTVKGVTQVTTQPKLGEVQQKCHQFC
Spur_spur_RNGTT.AA               AASSKKQGGGGGRNKNQQDK---------QFVEG--VKGVTVVTDFQKANHLRRKVEQMV
                                                               *       ..           :.

Mbre_mbre_RNGTT.AA               GAQEGTAFPGSQPVSLNRDSLLDLSRADYMISWKSDGTRYLMLLAD-QKVYFVGRDNNYF
Cele_cel-1.AA                    KY-NKQGFPGLQPVSLSRGNINLLEQESYMVSWKADGMRYIIYIND-GDVYAFDRDNEVF
Aque_aque_RNGTT-A.AA             DW-EESGFPGSQPVSMDVQNIRFLNEKPYRVSWKADGTRYMLYIKGKGQIYLIDRDNSVF
Aque_aque_RNGTT-B.AA             DW-EESGFPGSQPVSMDVQNIRFLNEKPYRVSWKADGTRYMLYIKDKGHIYLIDRDNSVF
Dmel_mRNA-capping-enzyme.AA      DW-KKNGFPGAQPVSMDRENIKRLSEIPYRVSWKADGTRYMMLIDGRDEVYFFDRNHSCF
Nvec_nvec_RNGTT.AA               KF-ELNGFPGSQPVSMDRQNIRFLHEKDYRVSWKADGTRYMMLVVGEGQVYLIDRDNAVF
Hsap_RNGTT.AA                    GW-EGSGFPGAQPVSMDKQNIKLLDLKPYKVSWKADGTRYMMLIDGTNEVFMIDRDNSVF
Spur_spur_RNGTT.AA               GW-KRQEFPGSQPVSMDRNNINFLKKNYYWVSWKADGIRYMMLIDGPGEVYLFDRDHVVF
                                    :   *** ****:.  .:  *    * :***:** **:: : .   :: ..*::  *

Mbre_mbre_RNGTT.AA               CVAGKVRFPNQDLKSVH-QNTLLDGEMVYDCWKDPATKKKQYRARFYIFDMIACNG-ESF
Cele_cel-1.AA                    EIE-NLDFVTKNGAP--LMETLVDTEVIID--KVEINGAMCDQPRMLIYDIMRFNS-VNV
Aque_aque_RNGTT-A.AA             NSP-NITFLSRKREGEHLRDCVADSELVLD----KVDGAV--RPRLLIYDIMMFEGSKDV
Aque_aque_RNGTT-B.AA             NSP-NITFLSRKREGEHLRDCVADSELVLD----KVDGAV--RPRLLIYDIMMFEGSKDV
Dmel_mRNA-capping-enzyme.AA      QVE-NVTFVESRNLNEHLDGTLVDGEMVLD----KIGETV--TPRYLIYDIVRLSN-RDV
Nvec_nvec_RNGTT.AA               SAP-QFRFPQRKNPREHIFDTLIDGEMVFD----KEGDKI--HPRYLAYDIIKFQ--VPG
Hsap_RNGTT.AA                    HVS-NLEFPFRKDLRMHLSNTLLDGEMIID----RVNGQA--VPRYLIYDIIKFNS-QPV
Spur_spur_RNGTT.AA               SAP-HLSFPNRKGPH---RDTLVDGEMIID----TVDGKS--VARYLIYDIIKYWG-KPV
                                     :. *             : * *:: *             .*   :*::

Mbre_mbre_RNGTT.AA               RHKPY-NERLEAVQTHILNPRLKQSTWPGYKEKYAQEPFSVRLKPFLPLADFQSDQWRKM
Cele_cel-1.AA                    MKEPF-YKRFEIIKTEIIDMRTAAFK-TGRLKH-ENQIMSVRRKDFYDLEATAKLFGPKF
Aque_aque_RNGTT-A.AA             ARCDH-QRRMLCIDRELIMPREEAAK-RGIIDK-IREPFSVRAKQFWDVSESRMILE-KY
Aque_aque_RNGTT-B.AA             AKCDH-QRRMLCIDRELIMPREEAAK-RGIIDK-IREPFSVRAKQFWDVSESRMILE-SY
Dmel_mRNA-capping-enzyme.AA      RDEPFYPNRLDYIKTEVIGPRILGMK-HGIINQ-RLQAFSVRGKDFWDIWMSARLLGEKF
Nvec_nvec_RNGTT.AA               KIVPGHAPCATCFDVQ-----------QGLLNK-TQEPFSIRAKQFFPLEKTAWILE-HW
Hsap_RNGTT.AA                    GDCDF-NVRLQCIEREIISPRHEKMK-TGLIDK-TQEPFSVRNKPFFDICTSRKLLEGNF
Spur_spur_RNGTT.AA               GGCDF-GWRRRCIQDEIIAPREVELQ-KGSIDR-MREPFGIREKPFWDITSSKKILDGSF
                                             ..              *  ..   : :.:* * *  :

Mbre_mbre_RNGTT.AA               RSQVQHKDDGLLLVRVAHEYKAGSCKALLKWKPAHLNTIDFRLKVEDIG-----DRTVGT
Cele_cel-1.AA                    VQHVGHEIDGLIFQPKKTKYETGRCDKVLKWKPPSHNSVDFLLKVEKKCKEGMLPEWIGY
Aque_aque_RNGTT-A.AA             APTLTHENDGLIYNPTNEPYKPGQCKDLLIWKPPKVN---FHLNIITEKKFGMLEEKKAQ
Aque_aque_RNGTT-B.AA             VPKLTHENDGLIYNPTNQPYKPGQCQDLLKWKPPELNTVDFRLNIISEQKVGMLQEKKAQ
Dmel_mRNA-capping-enzyme.AA      SRTLAHEPDGLIFQPSKQPYTAGTCSDVFKWKPHELNSVDFRLKIITERGEGLLTKKVGF
Nvec_nvec_RNGTT.AA               VPKLTHENDGLIFNPAEDPYLPGRQASVLKWKPHTLNSVDFILKIATVKQEGCLPRSVGY
Hsap_RNGTT.AA                    AKEVSHEMDGLIFQPTGK-YKPGRCDDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGL
Spur_spur_RNGTT.AA               SQELMHETDGLIFQPHKDPYIPGRCDLILKWKPPSLNSVDFRIKVTVVKREGCIPETLGL
                                    : *: ***:       * .*    :: ***   *   * :::             .

Mbre_mbre_RNGTT.AA               LYVQDVRGRGSERPEVKFTGMGSPELNTFVPQERQQLWAYDGKIVECNWLSDLNR----W
Cele_cel-1.AA                    LFV----QNLSD----PFGTM----------KATATLKKYHNKIIECTLLVDNQGRPKEW
Aque_aque_RNGTT-A.AA             LLV----GSERCEKIFSYLDL----------QVNKDAKKHSKKIIECSF-VN-NK----W
Aque_aque_RNGTT-B.AA             LLV----GSGRHTVLFSYLDL----------HVNKEAKAHNNKIIECSF-VD-KK----W
Dmel_mRNA-capping-enzyme.AA      LYV----GGHDA----PYGRM---------QRLTKETRELDNRIVECTM-NQFGN----W
Nvec_nvec_RNGTT.AA               LMV----GGFDR----PFAEI----------KVTKELKAYNNRVIECTW-DN-KE----W
Hsap_RNGTT.AA                    LYV----GGYER----PFAQI----------KVTKELKQYDNKIIECKF-EN-NS----W
Spur_spur_RNGTT.AA               LFV----GGQQQ----PFGQM----------KITKDLKQYDNKIIECSY-NNKKG----W
                                 * *              :  :          .     .    .::**.   :       *

Mbre_mbre_RNGTT.AA               NILLERKDKTHPNAFHTAINVVGSIRDGIELRELEDVADRKRQERA-----------KRG
Cele_cel-1.AA                    KFMRERTDKSLPNGLRTAENVVETMVNPVTETYLIEYVNHALRVLKRA-------AAAHR
Aque_aque_RNGTT-A.AA             KFLRVRTDKGFPDSIETAKSIC---IDSVNEDKLLEVCEKHRRGIDK--------GRANK
Aque_aque_RNGTT-B.AA             KFLRVRTDKSFPNSFETARSVCMSISQPVTKQWLLEVCEKYRWGIDK--------GRANK
Dmel_mRNA-capping-enzyme.AA      DFMRERTDKKNPNSYNTARSVVDSIKHPVTKEYLLNFIASSGYRNDHVMMPPPINSHNQN
Nvec_nvec_RNGTT.AA               KFLRVREDKSHANAYTTAQGVCESIRNPVTKEWLLEVIEKYRFRKD---------NHHHR
Hsap_RNGTT.AA                    VFMRQRTDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCTAASQ---------GQKRK
Spur_spur_RNGTT.AA               QFMRERTDKSFPNGYKTAVAVCQSIQNPVTKDFLMNFIDKEAIKPSSNKRPADNSSSSSS
                                  ::  * **  .:.  **  :       :    * :

Mbre_mbre_RNGTT.AA               HVQVHH---------------QQAGMPAKRSKPDGSA----
Cele_cel-1.AA                    HHQIHQ---------------QQLHEGEPEARRQKL-----
Aque_aque_RNGTT-A.AA             HALEEP---------------NGSMLPPSKARRHASTST--
Aque_aque_RNGTT-B.AA             HPLEEP---------------HGSMLPPTKAPRHTATQA--
Dmel_mRNA-capping-enzyme.AA      HNHNHF---------------YPHGHGQHQRRPCVNPTLGN
Nvec_nvec_RNGTT.AA               PHQHHQ---------------QQHHHSQQQHRPHPAQAPS-
Hsap_RNGTT.AA                    HHLDPD---------------TELMPPPPPKRPRPLT----
Spur_spur_RNGTT.AA               SPRPPPAKQQRTDSHPPSSLASGPGRPSSSLMPPPPAPLHH