Phosphatase Gene PPM1F

Phosphatase Classification: Superfamily PPM (PP2C): Family PPM (PP2C): Gene PPM1F

PPM1F is also known as POXP2, CAMKP, FEM-2, hFEM-2, CaMKPase). It as well as Gene PPM1E dephosphorylates and regulates multifunctional Ca(2+)/calmodulin-dependent protein kinases (CaMKs) [1]. PPM1E is localized in the nucleus, but PPM1F is localized in the cytosol [2].

References

1. Ishida A, Tada Y, Nimura T, Sueyoshi N, Katoh T, Takeuchi M, Fujisawa H, Taniguchi T, and Kameshita I. Identification of major Ca(2+)/calmodulin-dependent protein kinase phosphatase-binding proteins in brain: biochemical analysis of the interaction. Arch Biochem Biophys. 2005 Mar 1;435(1):134-46. DOI:10.1016/j.abb.2004.11.022 |
2. Takeuchi M, Taniguchi T, and Fujisawa H. Identification and characterization of nuclear localization signals of CaMKP-N. J Biochem. 2004 Aug;136(2):183-8. DOI:10.1093/jb/mvh109 |