Difference between revisions of "Phosphatase Subfamily PAPL"
From PhosphataseWiki
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PAPL subfamily is found in [[Phosphatase_Glossary#Holozoa|holozoa]] but lost from most arthropods. Humans have a single member, PAPL, but many invertebrates have multiple members | PAPL subfamily is found in [[Phosphatase_Glossary#Holozoa|holozoa]] but lost from most arthropods. Humans have a single member, PAPL, but many invertebrates have multiple members | ||
| − | === Domain === | + | === Domain Structure === |
| − | PAPL has a phosphatase domain and a signal peptide cleavage site on N-terminus. | + | PAPL has a phosphatase domain and a signal peptide cleavage site on N-terminus. Though predicted to be secreted, human PAPL is found mostly in the cytoplasm (http://www.proteinatlas.org/ENSG00000183760-PAPL/tissue). |
=== Function === | === Function === | ||
Unclear. | Unclear. | ||
Revision as of 22:44, 7 April 2015
Phosphatase Classification: Fold MTDP:Superfamily MTDP: Family PAP: PAPL
Evolution
PAPL subfamily is found in holozoa but lost from most arthropods. Humans have a single member, PAPL, but many invertebrates have multiple members
Domain Structure
PAPL has a phosphatase domain and a signal peptide cleavage site on N-terminus. Though predicted to be secreted, human PAPL is found mostly in the cytoplasm (http://www.proteinatlas.org/ENSG00000183760-PAPL/tissue).
Function
Unclear.
