Difference between revisions of "Phosphatase Subfamily PPP5C"
From PhosphataseWiki
(→Domain) |
|||
| Line 6: | Line 6: | ||
=== Domain === | === Domain === | ||
| − | + | PPP5Cs typically have tandem [[Protein_Domain#TPR|tetratricopeptide repeats (TPRs)]] at N-terminal and phosphatase domain at C-terminal. Dictystelium has an additional but partial TPR of ~30 aa residues. | |
=== Functions === | === Functions === | ||
Revision as of 16:40, 18 June 2015
Phosphatase Classification: Fold MTDP: Superfamily MTDP: Family PPP: Subfamily PPP5C
Evolution
The PPP5C subfamily is found throughout eukaryotes, including opisthokonta, amoebazoa, plants and etc. PPP5Cs have tandem tetratricopeptide repeat (TPR) structural motifs at N-terminal, which distinguish them from other PPP subfamilies, and were used to find and classify PPP5C in yeast and dicty in phosphatome.net database.
Domain
PPP5Cs typically have tandem tetratricopeptide repeats (TPRs) at N-terminal and phosphatase domain at C-terminal. Dictystelium has an additional but partial TPR of ~30 aa residues.
Functions
PPP5C is the catalytic subunit of holoenzyme PP5, the function of which is reviewed at [1].
