Difference between revisions of "Phosphatase Sequence AqueP003 AA"
From PhosphataseWiki
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[http://metazoa.ensembl.org/Amphimedon_queenslandica/Transcript/Sequence_Protein?db=core;g=Aqu1.222977;r=Contig13453:17825-19152;t=PAC:15721505 Ensembl Genomes] | [http://metazoa.ensembl.org/Amphimedon_queenslandica/Transcript/Sequence_Protein?db=core;g=Aqu1.222977;r=Contig13453:17825-19152;t=PAC:15721505 Ensembl Genomes] | ||
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Latest revision as of 02:12, 25 June 2015
Sequence version 1.1
The 1.1 version removes the two additional domains at C-terminal. The domain combination of three domains is not found in other genes, even the closest organisms to sponge, by BLASTing the full sequence of 1.0 version against NR database. Thus, it is more possible that the two domains belong to another one or two genes.
The original gene model has a better match (lower E-value), covering the DSPc profile from 1-132. The sequence version 1.0 covers from 39-132. Thus, the original gene model is used as version 1.1.
MPINNQELLKQVHFTGEADCQEFHPHPLRPSLCTDCNKLFSKHEPGAIPNDEALLQALAHSTKAEKTPDRILTTSSGGGLYLGGFRGVINTQFLREANVTHIVNTAKGLEIFGPKYLTAVQEARDILKINFLELNWEDTETWLIPDSDIRTLCNYIQTGLDMQGQSVFVHCAQGKSRSSTAVVAYVMVAKGLSLKESLGLVQSLHKMAEPNPHFMKRLEEFEKSELLQELRQAIRI
Sequence version 1.0
The 1.0 version updates the original gene model with an insertion and two additional domains to the C-terminal: an Adenosine/AMP deaminase domain and a possible lysine decarboxylase.
MPINNQELLKQVHFTGEADCQEFHPHPLRPSLCTDCNKLFSKHEPGAIPNDEALLQALAHSTKAEKTPDRILTTSSGGGLYLGGFRGVINTQFLREANVTHIVNTAKGLEIFGPKYLVGKVYTVSANEIICYDCMISSSQTAVQEARDILKINFLELNWEDTETWLIPDSDIRTLCNYIQTGLDMQGQSVFVHCAQGKSRSSTAVVAYVMVAKGLSLKESLGLVQSLHKMAEPNPHFMKRLEEFENNKMADPTQSLLYYIEDIPKAELHIHIEGTLEPELMFKLAERNGIKLEGTVSSHKDRRQTFKNLQDFLDLYYEACSVLKEEEDFFDLMNAYLQKAAHDSVLVAEIFFDPQTHTERGVPFETVINGLHRGLCHGYQHYNIKGSLILCFLRHLSEDEAIKTLKEAMPHLDKIIGVGLDSGEVGNPPEKFEKVFSMARDLGLQVVAHAGEEGGPEYITGALDCLKAKRIDHGVQCLSSDELVSSLVARKIPLTVCPLSNIKLQVASRYFNGASPVKQLLDKGLLVTINSDDPAYFGGYINANFVQAVKDCKLTAKDVFNICRNAFNATFLPLVEKEYYLSCLNRFNVESGFAAPPKSVAIFGSRQPAPGTPQYEMARKLAGMFASRGYQVASGGYNGIMKAASHGANDEGGLSLGVLSPRTFRSRNPIGNEYVSKTMLSLSFSSRTSDLIETSEYLIAFPGKMGTFTEIIVSWSHWVGRSERNYPAKKLYIYREPLGTLFQDVVKRLGVSDAEIEHVILFDSLDEVLEGVERDFEERKKKAVF
Original gene model
MPINNQELLKQVHFTGEADCQEFHPHPLRPSLCTDCNKLFSKHEPGAIPNDEALLQALAHSTKAEKTPDRILTTSSGGGLYLGGFRGVINTQFLREANVTHIVNTAKGLEIFGPKYLTAVQEARDILKINFLELNWEDTETWLIPDSDIRTLCNYIQTGLDMQGQSVFVHCAQGKSRSSTAVVAYVMVAKGLSLKESLGLVQSLHKMAEPNPHFMKRLEEFEKSELLQELRQAIRI
