Difference between revisions of "Phosphatases and Diseases"
From PhosphataseWiki
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== Other diseases == | == Other diseases == | ||
| − | ==== [Phosphatase_Gene_SBF1|SBF1]]: Charcot-Marie-Tooth disease ==== | + | ==== [[Phosphatase_Gene_PDP1|PDP1]]: pyruvate dehydrogenase (PDH) deficiency ==== |
| + | See [http://omim.org/entry/608782 OMIM]. | ||
| + | |||
| + | ==== [[Phosphatase_Gene_SBF1|SBF1]]: Charcot-Marie-Tooth disease ==== | ||
See [http://omim.org/entry/603560 OMIM]. | See [http://omim.org/entry/603560 OMIM]. | ||
| − | ==== [Phosphatase_Gene_PPM1K|PPM1K]]: | + | ==== [[Phosphatase_Gene_PPM1K|PPM1K]]: maple syrup urine disease ==== |
See [http://omim.org/entry/611065 OMIM]. | See [http://omim.org/entry/611065 OMIM]. | ||
Revision as of 04:21, 6 June 2014
Cancer
PTEN
PTPN11 (SHP2)
PTPRC (CD45)
DUSP3 (VHR)
DUSP3 is a negative regulator of ERK and JNK pathways in in vitro studies in several cell lines. Though its role is involved in human cancer, its has contradictory roles since it has been alternatively described as having tumor suppressive and oncogenic properties [1].
DUSP26 (MKP8)
DUSP26 (aka MKP8) is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma [2].
PPM1D (WIP1)
PPM1D as a frequent target of somatic mutation and as a potential therapeutic target in brainstem gliomas [3].
Parkinson's disease
DNAJC6
See OMIM.
Other diseases
PDP1: pyruvate dehydrogenase (PDH) deficiency
See OMIM.
SBF1: Charcot-Marie-Tooth disease
See OMIM.
PPM1K: maple syrup urine disease
See OMIM.
MTMR14: centronuclear myopathy
See OMIM.
PTPRQ: deafness
See OMIM.
References
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Error fetching PMID 24880341:
Error fetching PMID 20562916:
Error fetching PMID 24880341:
- Error fetching PMID 24886454:
- Error fetching PMID 20562916:
- Error fetching PMID 24880341:
